High Risk Program

Houston Methodist provides a high-risk program with comprehensive cancer risk assessment for breast cancer, gastrointestinal (GI), as well as uterine and ovarian cancers. In addition to risk assessment, in our specialized programs we offer education in nutrition, genetic counseling and, when appropriate, genetic testing. Patients can receive counseling on options for more intensive surveillance and additional risk reduction.

Learn more about risk factors related to:


Risk Factors for Breast Cancer
The high-risk breast cancer program at Houston Methodist provides a comprehensive breast cancer risk assessment, regular clinical exams, nutrition and genetic counseling and, when appropriate, genetic testing for women who are at higher-than-average risk of developing breast cancer.

The screenings your physician recommends will depend on your risk factors for developing breast cancer. Keep in mind that having one or more risk factors does not mean you will get the disease, and having no risk factors does not mean you cannot get it.

  • Having an inherited mutation in the BRCA1 and BRCA2 genes, or certain other genes (learn more about BRCA1 and BRCA2)
  • Having a family history of breast cancer
  • Family history of other cancers, such as ovarian, endometrial, prostate, pancreatic or colon cancers
  • Having had radiation exposure to the chest (E.g., mantel radiation for lymphoma)
  • Being of Ashkenazi Jewish ancestry

Risk Factors for Gastrointestinal Cancers
The high-risk gastrointestinal cancer program provides a comprehensive colon cancer risk assessment, personalized screening plans, genetic counseling and testing, when appropriate, as well as nutrition guidance.

  • A family history of GI cancer, especially before the age of 50
  • Family history of other types of cancers, such as endometrial, small bowel, pancreatic, breast, and ovarian cancers
  • Several colon polyps
  • A personal or family history of rare cancers
  • Having inherited one of the genes known to be associated with increased risk for colon cancer (E.g., MLH1, MSH2, MSH6, PMS2)

Risk Factors for Uterine and Ovarian Cancers
The high risk gynecology program provides comprehensive risk assessment for ovarian and endometrial cancer, personalized screening plans, genetic counseling and testing, when appropriate, as well as nutrition guidance.

Certain risk factors for ovarian and endometrial cancer are out of our control, such as age of first period, age of first birth, and age of menopause. There are other factors that we may have more control over, such as body weight.


The screenings your physician recommends will depend on your risk factors for developing uterine or ovarian cancer. Keep in mind that having one or more risk factors does not mean you will get the disease, and having no risk factors does not mean you cannot get it.
It is important that you and your doctor are aware of any factors that could increase your risk of developing uterine or ovarian cancer. Studies have linked several factors to the risk for these cancers:

Ovarian

  • Family history of ovarian cancer
  • Family history of other cancers, such as breast, endometrial or colon cancer
  • Being of Ashkenazi Jewish ancestry
  • Having inherited a mutation in BRCA1 or BRCA2, or certain other genes

 Uterine (Endometrial)
  • Family history of endometrial cancer
  • Family history of other cancers, such as ovarian, breast, or colon cancer
  • Having inherited a mutation genes known to be associated with endometrial cancer, such as MLH1, MSH2, MSh6, PMS2

TREATMENT LOCATIONS

Our physicians specialize in managing high risk cancers at the following convenient Houston Methodist Cancer Center locations.