Pancreatic Cancer Treatment

The gastrointestinal and oncology specialists at Houston Methodist work together in the diagnosis  and treatment of pancreatic cancer. Our highly trained experts provide cancer care at each of our eight locations across the Greater Houston, Texas area, so you can receive advanced care close to home.

Our oncologists work as a team to deliver leading-edge treatments for pancreatic cancer, including pancreatic adenocarcinomas and pancreatic neuroendocrine tumors (PNET). Our surgeons have extensive expertise performing the Whipple procedure, a complex procedure considered the primary surgical treatment for pancreatic cancer. 

We also offer access to innovative clinical trials  that can provide promising new pancreatic cancer treatments not yet available to the public.

 

 

Ranked #18 in the Nation for Cancer Care by U.S. News & World Report

Houston Methodist Hospital is ranked a top hospital in the nation by U.S. News & World Report for cancer. U.S. News & World Report has also named Houston Methodist Hospital one of the nation's best as a nationally ranked Honor Roll hospital.


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The 4 Stages of Pancreatic Cancer

If you receive a pancreatic diagnosis, your oncologist will determine the stage to understand the cancer size, location and metastasis (spread). Cancer staging helps your health care team know what areas of the body are affected and in need of treatment:

 

  • Stage 1 – Cancer is only located in the pancreas. It has not yet spread outside the pancreas.
  • Stage 2 – Cancer has spread outside the pancreas, possibly to nearby lymph nodes. It has not yet moved into a major blood vessel.
  • Stage 3 – Cancer has spread outside the pancreas and into nearby large blood vessels or major nerves.
  • Stage 4 – Cancer has spread into parts of the body far from the pancreas, such as the liver, lungs or inner lining of the abdomen. It is typically at this stage you may notice some symptoms.

Treating Pancreatic Cancer

We are committed to superior outcomes from diagnosis through treatment and recovery. The board-certified pancreatic surgeons at Houston Methodist are specially trained with expertise in managing the full spectrum of diseases of the pancreas.

If you receive a pancreatic cancer diagnosis, your oncology care team tailors your specific treatment plan to the unique characteristics of your type and stage of pancreatic cancer. We also consider your individual needs and lifestyle.

Diseases of the pancreas can cause chronic issues that impact health for years. Our medical professionals strive to provide life-altering interventions. Our goal is to treat your cancer and manage your pain — all while preserving healthy tissue and cells. Your care team may use one or more of the following methods to treat and manage the cancer.

Surgery

The following surgical procedures may be conducted to remove the cancer from the pancreas:

 

  • Whipple procedure (pancreaticoduodenectomy) – This surgery resects (removes) tumors located on the head (right side) of the pancreas. The first part of the small intestine (duodenum), gallbladder, part of the bile duct and nearby lymph nodes are typically removed as well.
  • Removal of the pancreatic body and tail (distal pancreatectomy) – This surgery resects (removes) tumors located on the left side of the pancreas. The spleen may also be removed.
  • Removal of the entire pancreas (pancreatectomy) – This is a total resection (removal) of the pancreas.

Chemotherapy

Chemotherapy uses drugs to stop the growth of cancer cells by killing them or halting cell division and growth. This treatment is typically administered orally (by mouth) or intravenously (with an IV).

If your cancer is localized to the pancreas, chemotherapy may be combined with radiation therapy in a treatment called chemoradiation. This treatment is often administered before surgery to shrink the tumor and help make surgical removal more successful. It may be used after surgery to help ensure no cancer cells remain.

Radiation Therapy

For pancreatic cancer, radiation therapy may be used before or after surgery, or as an alternative treatment if surgery is not an option.

Radiation therapy uses high-energy X-rays or other types of radiation to kill cancer cells or keep them from growing in a targeted, specific area. Radiation works by targeting abnormal cells, damaging their DNA so they are unable to reproduce.

Targeted Therapy

Targeted therapy uses drugs that specifically recognize and target cancer cells to stop their growth without harming normal cells. Targeted therapeutic drugs often pinpoint specific mutations or proteins that are involved in the growth and survival of cancer cells.

Targeted therapy can be taken orally. Your doctor may use targeted therapy as an initial treatment or combined with other treatments.

Pancreatic Cancer Program Outcomes Among World’s Best

Pancreatic Cancer Program Outcomes Among World’s Best

Houston Methodist is a high-volume center with proven pancreatic cancer surgical outcomes — even with a higher risk patient population. Our program's seven experienced pancreatic surgeons provide superior treatment and outcomes.
Pancreatic Cancer Clinical Trials

Pancreatic Cancer Clinical Trials

Houston Methodist researchers conduct groundbreaking clinical trials, resulting in novel therapies to treat pancreatic cancer.


 
Counseling and Support for Pancreatic Cancer Patients and Caregivers

Cancer affects every aspect of your life. We offer access to highly skilled and specialized support professionals who provide compassionate care for you and your caregivers.  Let Us Help You ➝

Pancreatic Ductal Adenocarcinoma Study Unveils Key Molecular Differences Based on Tumor Location

A new study has found that pancreatic cancer cells are different based on their location in the pancreas, providing new information about tumors that could lead to better targeted treatments. About This Study ➝

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