Pancreatic Cancer Screening

If you are at a high risk for pancreatic cancer due to your family history or genetic predisposition, your doctor may order blood work or refer you to a gastroenterologist for annual screening as a preventive measure. Two types of tests commonly used are magnetic resonance imaging (MRI) and endoscopic ultrasound.

MRI – Your doctor will use advanced imaging equipment to take an MRI of your abdomen in order to look at your pancreas and other organs.

Endoscopic ultrasound – An endoscopic ultrasound can detect small pancreatic tumors that could be missed with an MRI. An endoscopic ultrasound is a thin tube with a camera at the end that is passed through the mouth and into the stomach. The ultrasound probe at the end allows imaging of the pancreas, stomach and small intestine.

If necessary, an ultrasound-guided biopsy (tissue sample) from the pancreas is taken. The procedure typically lasts about 15-30 minutes, and you can go home the same day.

Yes, pancreatic cancer can be curable, depending on the type and how soon you receive treatment. Early diagnosis can improve your treatment options and outcomes.

Survival rates vary, depending on your overall health, age and response to treatment. According to the National Cancer Institute, the five-year relative survival rate of pancreatic cancer (percentage of people alive five years after diagnosis) is 12.8%. 

The primary reason for the low survival rate is due to a lack of noticeable symptoms until later stages when the cancer has already spread (metastasized) to other organs and areas in the body.

The exact cause of pancreatic cancer is unknown. In most cases, pancreatic cancer occurs when the cells that line the ducts of the pancreas grow out of control, which is called pancreatic adenocarcinoma. This type accounts for 90% of pancreatic cancer cases.

Cancer can also form in the hormone-producing (neuroendocrine) cells of the pancreas, which is called a pancreatic neuroendocrine tumor (PNET) — although this type is much more rare.

There are ways you can reduce your risk for cancers of the pancreas, including dietary and lifestyle changes, regular screenings and genetic testing.

Know Your Family History

Your family history gives you a lot of information that can help you and your doctor potentially stay ahead of a cancer diagnosis.

According to the American Cancer Society, up to 10% of pancreatic cancers have a genetic cause. One of the most common genetic causes is Lynch syndrome, which is also associated with increased risk of colorectal, endometrial, ovarian, gastric, urinary tract and brain cancers.

Clinical genetic testing can help determine if you have mutated genes, such as the BRCA 2 gene, putting you at a higher risk.

Maintain a Healthy Lifestyle

A healthy lifestyle can help lower your risk of pancreatic cancer. Eat a balanced diet, get regular exercise and maintain a healthy weight. Eat plenty of fiber and reduce your intake of red and processed meats. Avoid smoking and reduce your alcohol and soda intake.

Get Regular Care From Your PCP

A crucial part of cancer prevention includes getting regular care before you notice any symptoms. Work with your primary-care provider (PCP) for your annual checkups, immunizations and any recommended screenings.

Pay Attention to Your Body
You know what's normal for your body and what’s not, so you can notice subtle changes first. Let your doctor know if you experience jaundice or other pancreatic cancer symptoms such as changes in bowel habits, persistent dark urine, indigestion or vomiting, abdominal pain or cramping, or unexplained weight loss.

Schedule an appointment with your physician right away if you have any concerns or questions.