Uterine, or Endometrial, Cancer

Uterine Cancer, also known as endometrial cancer, is abnormal cell growth in the lining of the uterus.

Causes and Risk Factors

  • Hormone fluctuations in estrogen and progesterone balance
  • Starting menstruation early — before age 12 — or beginning menopause later increases risk
  • Never getting pregnant
  • Age
  • Obesity
  • Hormone therapy for breast cancer
  • An inherited colon cancer syndrome — Hereditary nonpolyposis colorectal cancer (HNPCC) — increases the risk of colon cancer and other cancers


  • Vaginal bleeding after menopause
  • Bleeding between periods
  • An abnormal, watery or blood-tinged vaginal discharge
  • Pelvic pain


  • Pelvic exam
  • Ultrasound
  • Hysteroscopy – a thin, lighted tube (hysteroscope) is inserted through the vagina and cervix into the uterus
  • Biopsy
  • Surgery – dilation and curettage (D&C). Tissue is scraped from the lining of the uterus for analysis


Clinical Trials

Patients have the unique opportunity to participate in clinical trials that involve medications as well as gene and cell therapy often unavailable outside of research settings. Learn more >

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