Our gastrointestinal oncology specialists at Houston Methodist Neal Cancer Center are among the best worldwide in screening, diagnosing and treating colorectal cancer . We are committed to ensuring you or your loved one receive expert care in a compassionate, collaborative and innovative environment — care we would provide our own families. As such, we employ a team-based approach to screening, diagnosing and treating your specific type of colorectal cancer, as well as creating personalized treatment plans tailored to your unique needs.

Colorectal Cancer Symptoms

You can have polyps or colon or rectal cancer and not know it. Colorectal cancer rarely causes noticeable symptoms in its earliest stages. As the disease progresses, there may be symptoms. Some are obvious, while others are more subtle.

See your doctor if you experience any new, persistent or unexplained symptoms such as:

 

  • Abdominal pain, gas or cramping
  • Bleeding from the rectum
  • Bloating or a feeling of being full
  • Blood in the stool (black, dark or red color stools)
  • Changes in bowel habits or the texture of the stool (constipation or diarrhea)
  • Feeling weak or tired
  • Nausea or vomiting
  • Unexplained weight loss

 

Learn more about colorectal cancer symptoms ➝

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Types of Colorectal Cancer

Colorectal cancers include cancers of the colon and rectum. Colon cancer is in the colon, which makes up most of your large intestine, where water and the remainder of nutrients are absorbed, and stool is formed. Rectal cancer is in the rectum, the final few inches of your large intestine where waste is stored until excreted during a bowel movement.

 

Adenocarcinomas account for 98% of colorectal tumors. An adenocarcinoma typically begins as a polyp called an adenoma that develops in the mucosal lining of the colon or rectum. Polyps are removed if discovered during a colonoscopy . 

 

The remaining 2% of cancers that develop in the colon or rectum are made up of the following:

 

  • Gastrointestinal carcinoid tumor – This tumor develops in special cells called neuroendocrine cells lining the gastrointestinal tract of the colon and rectum.
  • Gastrointestinal stromal tumor (GIST) – This tumor starts in the stomach, developing in the cells of the nervous system that signal the gastrointestinal tract wall to contract.
  • Primary colorectal lymphoma – This tumor develops in the immune cells of the colon and rectum.
  • Squamous cell carcinoma – This tumor typically affects the anus and sometimes the rectum. 
 

Why Choose Houston Methodist for Colorectal Cancer Care

Our multidisciplinary team of colorectal cancer experts has decades of experience providing innovative care, delivered with compassion. Oncology nurse navigators guide you through every stage of colorectal cancer care — from diagnosis and treatment through recovery.
Personalized Diagnostics & Treatment Plans

Personalized Diagnostics & Treatment Plans

Treating your individual cancer — so you can get back to your life.

Oncologists, gastroenterologists, colorectal surgeons and other specialists work together to develop a personalized treatment plan tailored to your needs. We use advanced diagnostics and treatment options — including minimally invasive robotic surgical techniques, blood conservation techniques and targeted therapies — to treat your cancer as quickly and safely as possible.

 

Cutting-Edge Research & Innovative Technology

Cutting-Edge Research & Innovative Technology

Groundbreaking research and clinical trials lead to new treatment options for your cancer.

Our pioneering research and our many clinical trials  result in new therapies developed to treat and cure cancer. Houston Methodist patients may access clinical trials offering potentially promising treatments not yet available.

Ranked No. 7 in the Nation for Gastroenterology and GI Surgery by U.S. News & World Report

Houston Methodist Hospital is ranked No. 7 in the nation by U.S. News & World Report for gastroenterology and GI surgery. U.S. News & World Report also nationally ranks Houston Methodist for cancer and considers it high performing for colon cancer surgery.


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Colorectal Cancer Diagnosis

Colorectal Cancer Diagnosis

Regular screening of the colon and rectum by colonoscopy can help find colorectal cancer early before symptoms develop, when it is most likely to be curable. Screening can also help prevent colon and rectal cancer by finding and removing polyps that could have turned into cancer.

 

If you experience symptoms of colorectal cancer, your doctor may perform one or more diagnostic tests to confirm a diagnosis and determine the specific type and stage of the cancer. Common diagnostic tests include blood tests, endoscopic procedures, biopsies and imaging tests.

Comprehensive Colorectal Cancer Treatments

The board-certified colorectal surgeons at Houston Methodist are specially trained with expertise in managing the full spectrum of colon and rectal diseases. If you receive a colorectal cancer diagnosis, your oncology care team will tailor your specific treatment plan to the unique characteristics of your type and stage of colorectal cancer. We also consider your individual needs and lifestyle.

 

Our goal is to provide effective treatments while preserving healthy tissue and cells. Your care team may use one or more methods to treat and manage your cancer.

Surgery

If surgery is needed, our experts use minimally invasive and robotic surgical techniques whenever possible. These advanced procedures can result in less pain and fewer complications, so you recover more quickly.

 

A polypectomy is the removal of a polyp (or growth) from an organ. It is used most often for early-stage colorectal cancers. 

 

An Endoscopic Mucosal Resection (EMR) is a minimally invasive procedure that uses suction and saline water injected via a needle to remove a small tumor or an area of abnormal tissues.

 

Some colorectal cancers require removal of part of the colon, which is called a colectomy. During this procedure, the cancerous area of the colon is removed, as well as some healthy tissue. 

 

When complete removal of the colon and rectum is necessary, our surgeons may perform J-pouch surgery. The J-pouch is a small pouch formed from the end of the small intestine into a “J” shape where stool can wait until it is time for a bowel movement.

Reconstructive Procedures & Stents

In more advanced cases, our experts perform reconstructive procedures to spare tissue and preserve function and quality of life by avoiding colostomies whenever possible.

 

Endoluminal stent placement may be used for patients with blockages in the colon or rectum when surgical treatment is not initially possible or recommended for safety reasons. With an endoluminal stent placement, expanding metal stents are inserted using an endoscope (narrow tube) placed through the anus to relieve a bowel obstruction.

 

Chemotherapy

Chemotherapy uses drugs to stop the growth of cancer cells by killing them or halting cell division and growth. This treatment is typically administered orally (by mouth) or intravenously (with an IV).

 

For colorectal cancer treatment, chemotherapy may be used to destroy any cancer cells that remain after surgery. In some cases, chemotherapy may be given before surgery to help shrink tumors to make them easier to remove . Chemotherapy is also used when the cancer is more advanced and surgery is not feasible.

Radiation & Targeted Therapies

Radiation therapy is commonly used before surgery for rectal cancer.  Radiation therapy uses high-energy X-rays or other types of radiation to kill cancer cells or keep them from growing in a targeted, specific area. Radiation works by targeting abnormal cells, damaging their DNA so they are unable to reproduce.

Targeted therapy uses drugs that specifically recognize and target cancer cells to stop their growth without harming normal cells. Targeted therapeutic drugs often pinpoint specific mutations or proteins that are involved in the growth and survival of cancer cells.

Houston Methodist Colorectal Cancer Specialists

At Houston Methodist Neal Cancer Center, our experienced team of colorectal cancer specialists — including medical, surgical and radiation oncologists, oncology-certified nurses, nurse navigators and support staff — is dedicated to stopping your cancer. We provide advanced cancer care at eight locations across the Greater Houston area, allowing you or your loved one to receive treatment close to home or work.

Colorectal Cancer Related Articles, News & Events

On Health Blog — Lifestyle & Wellness
Leading Medicine Blog — For Physicians
In The News — Recent Press
Events — Virtual & In-Person

Colorectal Cancer Education & Awareness

We recognize that the sheer volume of colon and rectal cancer information out there can be overwhelming, so we have streamlined it below to make it easier for you to digest as well as to make sure you understand what you absolutely need to know.
  • Colorectal Cancer Information
  • Colorectal Cancer Risk Factors
  • The Five Stages of Colorectal Cancer
  • Colorectal Cancer Information

    Colorectal Cancer Information

    Colorectal cancer is the fourth most common cancer, making it relatively common compared to other cancers. According to the National Cancer Institute, an estimated 152,810 new cases of colorectal cancer will be diagnosed in the United States in 2024.

    According to the National Cancer Institute, colorectal cancer accounts for 7.6% of all new cancer diagnoses and 8.7% of all cancer deaths.

  • Colorectal Cancer Risk Factors

    Colorectal Cancer Risk Factors

    A risk factor is anything that increases your odds of developing colorectal cancer, including genetic, environmental and lifestyle factors. It is important to be aware of your individual risk factors.

    Risk factors for developing colorectal cancer include advancing age, family history of cancer or lifestyle factors. However, we don’t always know why someone develops cancer.

    Personal and family history risk factors include:

     

    • Family history of colorectal cancer or adenomatous polyps (the most common type of colon polyp)
    • Personal history of colorectal polyps or colorectal cancer
    • Personal history of inflammatory bowel disease
    • Personal or family history of inherited syndromes: the most common are familial adenomatous polyposis (FAP) and hereditary nonpolyposis colon cancer (also called Lynch syndrome)

     

    Health and lifestyle risk factors include:

     

    • Diabetes mellitus
    • Heavy alcohol use
    • High consumption of red meat
    • High-fat diet low in fiber
    • Obesity
    • Sedentary lifestyles
    • Smoking

     

    Learn More About Colorectal Cancer Risk Factors  ➝

  • The Five Stages of Colorectal Cancer

    The Five Stages of Colorectal Cancer

    Our advanced testing methods and technologies offer precise cancer staging. The five stages of colorectal cancer include:

     

    • Stage 0 – Cancer is detected in the thin innermost lining (mucosa) of the colon or rectum. It has not spread.
    • Stage 1 – Cancer has spread beyond the inner layer into the muscular second (submucosa) or third (muscularis propria) layer but remains within the colon or rectum. It has not spread into nearby tissues or lymph nodes.
    • Stage 2 – Cancer has spread to the outer layers of the colon or rectum and into nearby tissues but not into lymph nodes.
    • Stage 3 – Cancer has grown outside the colon or rectum and into one or more lymph nodes. It has not spread into other parts of the body.
    • Stage 4 – Cancer has spread to other parts of the body such as the abdominal wall, liver, lungs or distant lymph nodes.

     

    The stage will be determined by your doctor based off your imaging and pathology results. 

Colorectal Cancer Frequently Asked Questions

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