Publications



Neuroinflammation co-localizes highly with tau in amnestic mild cognitive impairment
Appleton, J, Funk, Q, Bradbury, K, Yu, M, Faridar, A, Beers, D, Appel, SH, Fujita, M, Masdeu, JC & Pascual, B 2022, , Alzheimers and Dementia, vol. 18, no. S1, e068025. https://doi.org/10.1002/alz.068025

Ex vivo expanded human regulatory T cells modify neuroinflammation in a preclinical model of Alzheimer’s disease
Faridar, A, Vasquez, M, Thome, AD, Yin, Z, Xuan, H, Wang, JH, Wen, S, Li, X, Thonhoff, JR, Zhao, W, Zhao, H, Beers, DR, Wong, ST, Masdeu, JC & Appel, SH 2022, , Acta Neuropathologica Communications, vol. 10, no. 1, 144. https://doi.org/10.1186/s40478-022-01447-z

Imaging Neuroinflammation in Neurodegenerative Disorders
Masdeu, JC, Pascual, B & Fujita, M 2022, , Journal of nuclear medicine : official publication, Society of Nuclear Medicine, vol. 63, no. Suppl 1, pp. 45S-52S. https://doi.org/10.2967/jnumed.121.263200

Imaging Neuroinflammation in Neurodegenerative Disorders
Masdeu, JC, Pascual, B & Fujita, M 2022, , Journal of nuclear medicine : official publication, Society of Nuclear Medicine, vol. 63, no. Suppl 1, pp. 45S-52S. https://doi.org/10.2967/jnumed.121.263200


Comprehensive cross-sectional and longitudinal analyses of plasma neurofilament light across FTD spectrum disorders
Gendron, TF, Heckman, MG, White, LJ, Veire, AM, Pedraza, O, Burch, AR, Bozoki, AC, Dickerson, BC, Domoto-Reilly, K, Foroud, T, Forsberg, LK, Galasko, DR, Ghoshal, N, Graff-Radford, NR, Grossman, M, Heuer, HW, Huey, ED, Hsiung, GYR, Irwin, DJ, Kaufer, DI, Leger, GC, Litvan, I, Masdeu, JC, Mendez, MF, Onyike, CU, Pascual, B, Ritter, A, Roberson, ED, Rojas, JC, Tartaglia, MC, Wszolek, ZK, Rosen, H, Boeve, BF, Boxer, AL & ALLFTD consortium 2022, , Cell Reports Medicine, vol. 3, no. 4, 100607. https://doi.org/10.1016/j.xcrm.2022.100607


Translocator Protein 18 kDa PET Imaging Highlights Asymptomatic Isolated Cerebellar Dysplasia
Pascual, B, Hodics, T, Funk, Q, Cykowski, MD, Nakawah, MO & Masdeu, JC 2022, , Neurology, vol. 98, no. 13, pp. 538-539. https://doi.org/10.1212/WNL.0000000000200221


The PET tracer [11C]MK-6884 quantifies M4 muscarinic receptor in rhesus monkeys and patients with Alzheimer's disease
Li, W, Wang, Y, Lohith, TG, Zeng, Z, Tong, L, Mazzola, R, Riffel, K, Miller, P, Purcell, M, Holahan, M, Haley, H, Gantert, L, Hesk, D, Ren, S, Morrow, J, Uslaner, J, Struyk, A, Wai, JMC, Rudd, MT, Tellers, DM, McAvoy, T, Bormans, G, Koole, M, Van Laere, K, Serdons, K, De Hoon, J, Declercq, R, De Lepeleire, I, Pascual, MB, Zanotti Fregonara, P, Yu, M, Arbones, V, Masdeu, JC, Cheng, A, Hussain, A, Bueters, T, Anderson, MS, Hostetler, ED & Basile, AS 2022, , Science translational medicine, vol. 14, no. 627, eabg3684, pp. eabg3684. https://doi.org/10.1126/scitranslmed.abg3684

The PET tracer [11C]MK-6884 quantifies M4 muscarinic receptor in rhesus monkeys and patients with Alzheimer's disease
Li, W, Wang, Y, Lohith, TG, Zeng, Z, Tong, L, Mazzola, R, Riffel, K, Miller, P, Purcell, M, Holahan, M, Haley, H, Gantert, L, Hesk, D, Ren, S, Morrow, J, Uslaner, J, Struyk, A, Wai, JMC, Rudd, MT, Tellers, DM, McAvoy, T, Bormans, G, Koole, M, Van Laere, K, Serdons, K, De Hoon, J, Declercq, R, De Lepeleire, I, Pascual, MB, Zanotti Fregonara, P, Yu, M, Arbones, V, Masdeu, JC, Cheng, A, Hussain, A, Bueters, T, Anderson, MS, Hostetler, ED & Basile, AS 2022, , Science translational medicine, vol. 14, no. 627, eabg3684. https://doi.org/10.1126/scitranslmed.abg3684

The PET tracer [11C]MK-6884 quantifies M4 muscarinic receptor in rhesus monkeys and patients with Alzheimer's disease
Li, W, Wang, Y, Lohith, TG, Zeng, Z, Tong, L, Mazzola, R, Riffel, K, Miller, P, Purcell, M, Holahan, M, Haley, H, Gantert, L, Hesk, D, Ren, S, Morrow, J, Uslaner, J, Struyk, A, Wai, JMC, Rudd, MT, Tellers, DM, McAvoy, T, Bormans, G, Koole, M, Van Laere, K, Serdons, K, De Hoon, J, Declercq, R, De Lepeleire, I, Pascual, MB, Zanotti-Fregonara, P, Yu, M, Arbones, V, Masdeu, JC, Cheng, A, Hussain, A, Bueters, T, Anderson, MS, Hostetler, ED & Basile, AS 2022, , Science translational medicine, vol. 14, no. 627, eabg3684, pp. eabg3684. https://doi.org/10.1126/scitranslmed.abg3684

Alterations in brain synaptic proteins and mRNAs in mood disorders: a systematic review and meta-analysis of postmortem brain studies
Leung, E, Lau, EW, Liang, A, de Dios, C, Suchting, R, Östlundh, L, Masdeu, JC, Fujita, M, Sanches, M, Soares, JC & Selvaraj, S 2022, , Molecular Psychiatry, vol. 27, no. 3, pp. 1362-1372. https://doi.org/10.1038/s41380-021-01410-9

Patterns of amygdala region pathology in LATE-NC: subtypes that differ with regard to TDP-43 histopathology, genetic risk factors, and comorbid pathologies
Cykowski, MD, Arumanayagam, AS, Powell, SZ, Rivera, AL, Abner, EL, Roman, GC, Masdeu, JC & Nelson, PT 2022, , Acta Neuropathologica, vol. 143, no. 5, pp. 531-545. https://doi.org/10.1007/s00401-022-02416-5

In Alzheimer-prone brain regions, metabolism and risk-gene expression are strongly correlated
Ye, F, Funk, Q, Rockers, E, Shulman, JM, Masdeu, JC, Pascual, B & Alzheimers Disease Neuroimaging Initiative 2022, , Brain communications, vol. 4, no. 5, pp. fcac216. https://doi.org/10.1093/braincomms/fcac216

In Alzheimer-prone brain regions, metabolism and risk-gene expression are strongly correlated
Ye, F, Funk, Q, Rockers, E, Shulman, JM, Masdeu, JC & Pascual, B 2022, , Brain Communications, vol. 4, no. 5, fcac216. https://doi.org/10.1093/braincomms/fcac216

Higher CSF sTNFR1-related proteins associate with better prognosis in very early Alzheimer’s disease
Alzheimers Disease Neuroimaging Initiative 2021, , Nature Communications, vol. 12, no. 1, 4001. https://doi.org/10.1038/s41467-021-24220-7

Plasma phosphorylated-tau181 as a predictive biomarker for Alzheimer’s amyloid, tau and FDG PET status
Alzheimers Disease Neuroimaging Initiative 2021, , Translational Psychiatry, vol. 11, no. 1, 585. https://doi.org/10.1038/s41398-021-01709-9

Staging tau pathology with tau PET in Alzheimer’s disease: a longitudinal study
for the Alzheimer’s Disease Neuroimaging Initiative 2021, , Translational Psychiatry, vol. 11, no. 1, 483. https://doi.org/10.1038/s41398-021-01602-5