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Shu Meng, MD, PhD

Assistant Research Professor of Cardiovascular Sciences, Academic Institute
Assistant Research Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Vascular Regeneration in Peripheral Artery Disease
Meng, S & Cooke, JP 2020, , Arteriosclerosis, Thrombosis, and Vascular Biology, pp. 1627-1634.

Reservoir of fibroblasts promotes recovery from limb ischemia
Meng, S, Lv, J, Chanda, PK, Owusu, I, Chen, K & Cooke, JP 2020, , Circulation, pp. 1647-1662.

Dysfunction of iPSC-derived endothelial cells in human Hutchinson–Gilford progeria syndrome
Matrone, G, Thandavarayan, RA, Walther, BK, Meng, S, Mojiri, A & Cooke, JP 2019, , Cell Cycle, vol. 18, no. 19, pp. 2495-2508.

Nuclear S-nitrosylation defines an optimal zone for inducing pluripotency
Chanda, PK, Meng, S, Lee, J, Leung, HE, Chen, K & Cooke, JP 2019, , Circulation, vol. 140, no. 13, pp. 1081-1099.

AIBP-mediated cholesterol efflux instructs hematopoietic stem and progenitor cell fate
Gu, Q, Yang, X, Lv, J, Zhang, J, Xia, B, Kim, JD, Wang, R, Xiong, F, Meng, S, Clements, TP, Tandon, B, Wagner, DS, Diaz, MF, Wenzel, PL, Miller, YI, Traver, D, Cooke, JP, Li, W, Zon, LI, Chen, K, Bai, Y & Fang, L 2019, , Science, pp. eaav1749.

TBX20 Regulates Angiogenesis Through the Prokineticin 2-Prokineticin Receptor 1 Pathway
Meng, S, Gu, Q, Yang, X, Lv, J, Owusu, I, Matrone, G, Chen, K, Cooke, JP & Fang, L 2018, , Circulation, vol. 138, no. 9, pp. 913-928.

Transflammation: How Innate Immune Activation and Free Radicals Drive Nuclear Reprogramming
Meng, S, Chanda, P, Thandavarayan, RA & Cooke, JP 2018, , Antioxidants and Redox Signaling, vol. 29, no. 2, pp. 205-218.

Small molecule disruption of G protein ß? subunit signaling reprograms human macrophage phenotype and prevents autoimmune myocarditis in rats
Karuppagounder, V, Bajpai, A, Meng, S, Arumugam, S, Sreedhar, R, Giridharan, VV, Guha, A, Bhimaraj, A, Youker, KA, Palaniyandi, SS, Karmouty-Quintana, H, Kamal, F, Spiller, KL, Watanabe, K & Thandavarayan, RA 2018, , PLoS ONE, vol. 13, no. 7, e0200697.

Transflammation: Innate immune signaling in nuclear reprogramming
Meng, S, Chanda, P, Thandavarayan, RA & Cooke, JP 2017, , Advanced Drug Delivery Reviews, vol. 120, pp. 133-141.

Lmo2 (LIM-Domain-Only 2) Modulates Sphk1 (Sphingosine Kinase) and Promotes Endothelial Cell Migration
Matrone, G, Meng, S, Gu, Q, Lv, J, Fang, L, Chen, K & Cooke, JP 2017, , Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 37, no. 10, pp. 1860-1868.

AIBP Limits Angiogenesis Through ?-Secretase-Mediated Upregulation of Notch Signaling
Mao, R, Meng, S, Gu, Q, Araujo-Gutierrez, R, Kumar, S, Yan, Q, Almazan, F, Youker, KA, Fu, Y, Pownall, HJ, Cooke, JP, Miller, YI & Fang, L 2017, , Circulation Research, vol. 120, no. 11, pp. 1727-1739.

Discovery of novel determinants of endothelial lineage using chimeric heterokaryons
Wong, J, Matrone, G, Tian, X, Tomoiaga, SA, Au, KF, Meng, S, Yamazoe, S, Sieveking, D, Chen, K, Burns, DM, Chen, JK, Blau, HM & Cooke, JP 2017, , eLife, vol. 6, e23588.

Transdifferentiation Requires iNOS Activation: Role of RING1A S-Nitrosylation
Meng, S, Zhou, G, Gu, Q, Chanda, PK, Ospino, F & Cooke, JP 2016, , Circulation Research, vol. 119, no. 9, pp. e129-e138.

Optimal ROS Signaling Is Critical for Nuclear Reprogramming
Zhou, G, Meng, S, Li, Y, Ghebre, YT & Cooke, JP 2016, , Cell Reports, vol. 15, no. 5, pp. 919-925.

Role of innate immune signaling in nuclear reprogramming
Meng, S, Chanda, P & Cooke, JP 2016, . in Regenerative Medicine - from Protocol to Patient: 1. Biology of Tissue Regeneration: Third Edition. Springer International Publishing, pp. 291-305.

Response to letter regarding article "Transdifferentiation of human fibroblasts to endothelial cells: Role of innate immunity"
Cooke, JP, Meng, S, Wong, WT, Sayed, N, Ospino, F, Lee, J, Jha, A, Dexheimer, P & Aronow, B 2015, , Circulation, vol. 132, no. 15, pp. e197.

Interleukin-35 inhibits endothelial cell activation by suppressing MAPK-AP-1 Pathway
Sha, X, Meng, S, Li, X, Xi, H, Maddaloni, M, Pascual, DW, Shan, H, Jiang, X, Wang, H & Yang, XF 2015, , Journal of Biological Chemistry, vol. 290, no. 31, pp. 19307-19318.

Early Hyperlipidemia Promotes Endothelial Activation via a Caspase-1-Sirtuin 1 Pathway
Yin, Y, Li, X, Sha, X, Xi, H, Li, YF, Shao, Y, Mai, J, Virtue, A, Lopez-Pastrana, J, Meng, S, Tilley, DG, Monroy, MA, Choi, ET, Thomas, CJ, Jiang, X, Wang, H & Yang, XF 2015, , Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 35, no. 4, pp. 804-816.

Methylation and Atherosclerosis
Xiong, XY, Meng, S, Yang, X & Wang, H 2015, . in Atherosclerosis: Risks, Mechanisms, and Therapies. Wiley, pp. 405-421.

Monocytes and Macrophages in Atherosclerosis
Meng, S, Fang, P, Yang, X & Wang, H 2015, . in Atherosclerosis: Risks, Mechanisms, and Therapies. Wiley, pp. 141-153.