Haibo Wang, PhD

Instructor in Radiation Oncology, Academic Institute
Instructor, Research Institute
Houston Methodist

Publications

RT2 PCR array screening reveals distinct perturbations in DNA damage response signaling in FUS-associated motor neuron disease

Wang, H, Rangaswamy, S, Kodavati, M, Mitra, J, Guo, W, Guerrero, EN, Van Den Bosch, L & Hegde, M 2019, Molecular Brain, vol. 12, no. 1, 103. https://doi.org/10.1186/s13041-019-0526-4

Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis

Guerrero, EN, Mitra, J, Wang, H, Rangaswamy, S, Hegde, PM, Basu, P, Rao, KS & Hegde, ML 2019, Human Molecular Genetics, vol. 28, no. 18, pp. 3161-3162. https://doi.org/10.1093/hmg/ddz141

New mechanisms of dna repair defects in fused in sarcoma–associated neurodegeneration: Stage set for dna repair-based therapeutics?

Wang, H & Hegde, M 2019, Journal of Experimental Neuroscience, vol. 13. https://doi.org/10.1177/1179069519856358

Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects

Mitra, J, Guerrero, EN, Hegde, PM, Liachko, NF, Wang, H, Vasquez, V, Gao, J, Pandey, A, Paul Taylor, J, Kraemer, BC, Wu, P, Boldogh, I, Garruto, RM, Mitra, S, Rao, KS & Hegde, M 2019, Proceedings of the National Academy of Sciences of the United States of America, vol. 116, no. 10, pp. 4696-4705. https://doi.org/10.1073/pnas.1818415116

Sinomenine hydrochloride sensitizes cervical cancer cells to ionizing radiation by impairing DNA damage response

Zhang, D, Dong, Y, Zhao, Y, Zhou, C, Qian, Y, Hegde, M, Wang, H & Han, S 2018, Oncology reports, vol. 40, no. 5, pp. 2886-2895. https://doi.org/10.3892/or.2018.6693

Aurora kinase B dependent phosphorylation of 53BP1 is required for resolving merotelic kinetochore-microtubule attachment errors during mitosis

Wang, H, Peng, B, Pandita, RK, Engler, DA, Matsunami, RK, Xu, X, Hegde, PM, Butler, EB, Pandita, TK, Mitra, S, Xu, B & Hegde, ML 2017, Oncotarget, vol. 8, no. 30, pp. 48671-48687. https://doi.org/10.18632/oncotarget.16225

Speckle-type POZ protein, SPOP, is involved in the DNA damage response

Zhang, D, Wang, H, Sun, M, Yang, J, Zhang, W, Han, S & Xu, B 2014, Carcinogenesis, vol. 35, no. 8, pp. 1691-1697. https://doi.org/10.1093/carcin/bgu022

ATM-mediated Mad1 Serine 214 phosphorylation regulates Mad1 dimerization and the spindle assembly checkpoint

Yang, C, Hao, J, Kong, D, Cui, X, Zhang, W, Wang, H, Guo, X, Ma, S, Liu, X, Pu, P & Xu, B 2014, Carcinogenesis, vol. 35, no. 9, bgu087, pp. 2007-2013. https://doi.org/10.1093/carcin/bgu087

New perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseases

Mitra, J, Guerrero, EN, Hegde, PM, Wang, H, Boldogh, I, Rao, KSH, Mitra, S & Hegde, M 2014, Biomolecules, vol. 4, no. 3, pp. 678-703. https://doi.org/10.3390/biom4030678

Activation of the ATM-Snail pathway promotes breast cancer metastasis

Sun, M, Guo, X, Qian, X, Wang, H, Yang, C, Brinkman, KL, Serrano-Gonzalez, M, Jope, RS, Zhou, B, Engler, DA, Zhan, M, Wong, ST, Fu, L & Xu, B 2012, Journal of Molecular Cell Biology, vol. 4, no. 5, pp. 304-315. https://doi.org/10.1093/jmcb/mjs048

Strategies for targeting the DNA damage respones for cancer therapeutics

Zhang, D, Wang, H, Brinkman, KL, Han, SX & Xu, B 2012, Chinese Journal of Cancer, vol. 31, no. 8, pp. 359-363. https://doi.org/10.5732/cjc.012.10087

The kinetochore protein Bub1 participates in the DNA damage response

Yang, C, Wang, H, Xu, Y, Brinkman, KL, Ishiyama, H, Wong, ST & Xu, B 2012, DNA Repair, vol. 11, no. 2, pp. 185-191. https://doi.org/10.1016/j.dnarep.2011.10.018

CDK5RAP2 is required for spindle checkpoint function

Zhang, X, Liu, D, Lv, S, Wang, H, Zhong, X, Liu, B, Wang, B, Liao, J, Li, J, Pfeifer, GP & Xu, X 2009, Cell Cycle, vol. 8, no. 8, pp. 1206-1216.

Human RIF1 encodes an anti-apoptotic factor required for DNA repair

Wang, H, Zhao, A, Chen, L, Zhong, X, Liao, J, Gao, M, Cai, M, Lee, DH, Li, J, Chowdhury, D, Yang, YG, Pfeifer, GP, Yen, Y & Xu, X 2009, Carcinogenesis, vol. 30, no. 8, pp. 1314-1319. https://doi.org/10.1093/carcin/bgp136

Protein phosphatase PP4 is overexpressed in human breast and lung tumors

Wang, B, Zhao, A, Sun, L, Zhong, X, Zhong, J, Wang, H, Cai, M, Li, J, Xu, Y, Liao, J, Sang, J, Chowdhury, D, Pfeifer, GP, Yen, Y & Xu, X 2008, Cell Research, vol. 18, no. 9, pp. 974-977. https://doi.org/10.1038/cr.2008.274

Cloning and molecular characterization of three novel LMW-i glutenin subunit genes from cultivated einkorn (Triticum monococcum L.)

An, X, Zhang, Q, Yan, Y, Li, Q, Zhang, Y, Wang, A, Pei, Y, Tian, J, Wang, H, Hsam, SLK & Zeller, FJ 2006, Theoretical and Applied Genetics, vol. 113, no. 3, pp. 383-395. https://doi.org/10.1007/s00122-006-0299-x

Molecular characterization and phylogenetic analysis of a novel glutenin gene (Dy10.1t) from Aegilops tauschii

Zhang, Y, Li, Q, Yan, Y, Zheng, J, An, X, Xiao, Y, Wang, A, Pei, Y, Wang, H, Hsam, SLK & Zeller, FJ 2006, Genome, vol. 49, no. 7, pp. 735-745. https://doi.org/10.1139/G06-032

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