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Haibo Wang, PhD

Instructor in Radiation Oncology, Institute for Academic Medicine
Instructor, Research Institute
Houston Methodist


Publications

New mechanisms of dna repair defects in fused in sarcoma–associated neurodegeneration: Stage set for dna repair-based therapeutics?
Wang, H & Hegde, M 2019, Journal of Experimental Neuroscience, vol. 13. https://doi.org/10.1177/1179069519856358

Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects
Mitra, J, Guerrero, EN, Hegde, PM, Liachko, NF, Wang, H, Vasquez, V, Gao, J, Pandey, A, Paul Taylor, J, Kraemer, BC, Wu, P, Boldogh, I, Garruto, RM, Mitra, S, Rao, KS & Hegde, M 2019, Proceedings of the National Academy of Sciences of the United States of America, vol. 116, no. 10, pp. 4696-4705. https://doi.org/10.1073/pnas.1818415116

Aurora kinase B dependent phosphorylation of 53BP1 is required for resolving merotelic kinetochore-microtubule attachment errors during mitosis
Wang, H, Peng, B, Pandita, RK, Engler, DA, Matsunami, RK, Xu, X, Hegde, PM, Butler, EB, Pandita, TK, Mitra, S, Xu, B & Hegde, ML 2017, Oncotarget, vol. 8, no. 30, pp. 48671-48687. https://doi.org/10.18632/oncotarget.16225

ATM-mediated Mad1 Serine 214 phosphorylation regulates Mad1 dimerization and the spindle assembly checkpoint
Yang, C, Hao, J, Kong, D, Cui, X, Zhang, W, Wang, H, Guo, X, Ma, S, Liu, X, Pu, P & Xu, B 2014, Carcinogenesis, vol. 35, no. 9, bgu087, pp. 2007-2013. https://doi.org/10.1093/carcin/bgu087

New perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseases
Mitra, J, Guerrero, EN, Hegde, PM, Wang, H, Boldogh, I, Rao, KSH, Mitra, S & Hegde, M 2014, Biomolecules, vol. 4, no. 3, pp. 678-703. https://doi.org/10.3390/biom4030678

Speckle-type POZ protein, SPOP, is involved in the DNA damage response
Zhang, D, Wang, H, Sun, M, Yang, J, Zhang, W, Han, S & Xu, B 2014, Carcinogenesis, vol. 35, no. 8, pp. 1691-1697. https://doi.org/10.1093/carcin/bgu022

Activation of the ATM-Snail pathway promotes breast cancer metastasis
Sun, M, Guo, X, Qian, X, Wang, H, Yang, C, Brinkman, KL, Serrano-Gonzalez, M, Jope, RS, Zhou, B, Engler, DA, Zhan, M, Wong, ST, Fu, L & Xu, B 2012, Journal of Molecular Cell Biology, vol. 4, no. 5, pp. 304-315. https://doi.org/10.1093/jmcb/mjs048

Strategies for targeting the DNA damage respones for cancer therapeutics
Zhang, D, Wang, H, Brinkman, KL, Han, SX & Xu, B 2012, Chinese Journal of Cancer, vol. 31, no. 8, pp. 359-363. https://doi.org/10.5732/cjc.012.10087

The kinetochore protein Bub1 participates in the DNA damage response
Yang, C, Wang, H, Xu, Y, Brinkman, KL, Ishiyama, H, Wong, ST & Xu, B 2012, DNA Repair, vol. 11, no. 2, pp. 185-191. https://doi.org/10.1016/j.dnarep.2011.10.018

CDK5RAP2 is required for spindle checkpoint function
Zhang, X, Liu, D, Lv, S, Wang, H, Zhong, X, Liu, B, Wang, B, Liao, J, Li, J, Pfeifer, GP & Xu, X 2009, Cell Cycle, vol. 8, no. 8, pp. 1206-1216.

Human RIF1 encodes an anti-apoptotic factor required for DNA repair
Wang, H, Zhao, A, Chen, L, Zhong, X, Liao, J, Gao, M, Cai, M, Lee, DH, Li, J, Chowdhury, D, Yang, YG, Pfeifer, GP, Yen, Y & Xu, X 2009, Carcinogenesis, vol. 30, no. 8, pp. 1314-1319. https://doi.org/10.1093/carcin/bgp136

Protein phosphatase PP4 is overexpressed in human breast and lung tumors
Wang, B, Zhao, A, Sun, L, Zhong, X, Zhong, J, Wang, H, Cai, M, Li, J, Xu, Y, Liao, J, Sang, J, Chowdhury, D, Pfeifer, GP, Yen, Y & Xu, X 2008, Cell Research, vol. 18, no. 9, pp. 974-977. https://doi.org/10.1038/cr.2008.274

Cloning and molecular characterization of three novel LMW-i glutenin subunit genes from cultivated einkorn (Triticum monococcum L.)
An, X, Zhang, Q, Yan, Y, Li, Q, Zhang, Y, Wang, A, Pei, Y, Tian, J, Wang, H, Hsam, SLK & Zeller, FJ 2006, Theoretical and Applied Genetics, vol. 113, no. 3, pp. 383-395. https://doi.org/10.1007/s00122-006-0299-x

Molecular characterization and phylogenetic analysis of a novel glutenin gene (Dy10.1t) from Aegilops tauschii
Zhang, Y, Li, Q, Yan, Y, Zheng, J, An, X, Xiao, Y, Wang, A, Pei, Y, Wang, H, Hsam, SLK & Zeller, FJ 2006, Genome, vol. 49, no. 7, pp. 735-745. https://doi.org/10.1139/G06-032

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