Not found

Haibo Wang, PhD

Instructor in Radiation Oncology, Academic Institute
Instructor, Research Institute
Houston Methodist


Ligand-induced gene activation is associated with oxidative genome damage whose repair is required for transcription
Sengupta, S, Wang, H, Yang, C, Szczesny, B, Hegde, ML & Mitra, S 2020, , Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 36, pp. 22183-22192.

XRCC1 promotes replication restart, nascent fork degradation and mutagenic DNA repair in BRCA2-deficient cells
Eckelmann, BJ, Bacolla, A, Wang, H, Ye, Z, Guerrero, EN, Jiang, W, El-Zein, R, Hegde, ML, Tomkinson, AE, Tainer, JA & Mitra, S 2020, , NAR cancer, vol. 2, no. 3, pp. zcaa013.

Altered Mitochondrial Dynamics in Motor Neuron Disease: An Emerging Perspective
Kodavati, M, Wang, H & Hegde, M 2020, , Cells, vol. 9, no. 4.

A multi-faceted genotoxic network of alpha-synuclein in the nucleus and mitochondria of dopaminergic neurons in Parkinson's disease: Emerging concepts and challenges
Vasquez, V, Mitra, J, Wang, H, Hegde, PM, Rao, KS & Hegde, ML 2020, , Progress in Neurobiology, vol. 185, 101729.

RT2 PCR array screening reveals distinct perturbations in DNA damage response signaling in FUS-associated motor neuron disease
Wang, H, Rangaswamy, S, Kodavati, M, Mitra, J, Guo, W, Guerrero, EN, Van Den Bosch, L & Hegde, M 2019, Molecular Brain, vol. 12, no. 1, 103.

Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis
Guerrero, EN, Mitra, J, Wang, H, Rangaswamy, S, Hegde, PM, Basu, P, Rao, KS & Hegde, ML 2019, , Human Molecular Genetics, vol. 28, no. 18, pp. 3161-3162.

New mechanisms of dna repair defects in fused in sarcoma–associated neurodegeneration: Stage set for dna repair-based therapeutics?
Wang, H & Hegde, M 2019, , Journal of Experimental Neuroscience, vol. 13.

Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects
Mitra, J, Guerrero, EN, Hegde, PM, Liachko, NF, Wang, H, Vasquez, V, Gao, J, Pandey, A, Paul Taylor, J, Kraemer, BC, Wu, P, Boldogh, I, Garruto, RM, Mitra, S, Rao, KS & Hegde, M 2019, , Proceedings of the National Academy of Sciences of the United States of America, vol. 116, no. 10, pp. 4696-4705.

Sinomenine hydrochloride sensitizes cervical cancer cells to ionizing radiation by impairing DNA damage response
Zhang, D, Dong, Y, Zhao, Y, Zhou, C, Qian, Y, Hegde, ML, Wang, H & Han, S 2018, , Oncology Reports, vol. 40, no. 5, pp. 2886-2895.

Aurora kinase B dependent phosphorylation of 53BP1 is required for resolving merotelic kinetochore-microtubule attachment errors during mitosis
Wang, H, Peng, B, Pandita, RK, Engler, DA, Matsunami, RK, Xu, X, Hegde, PM, Butler, EB, Pandita, TK, Mitra, S, Xu, B & Hegde, ML 2017, , Oncotarget, vol. 8, no. 30, pp. 48671-48687.

New perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseases
Mitra, J, Guerrero, EN, Hegde, PM, Wang, H, Boldogh, I, Rao, KS, Mitra, S & Hegde, ML 2014, , Biomolecules, vol. 4, no. 3, pp. 678-703.

ATM-mediated Mad1 Serine 214 phosphorylation regulates Mad1 dimerization and the spindle assembly checkpoint
Yang, C, Hao, J, Kong, D, Cui, X, Zhang, W, Wang, H, Guo, X, Ma, S, Liu, X, Pu, P & Xu, B 2014, , Carcinogenesis, vol. 35, no. 9, bgu087, pp. 2007-2013.

Speckle-type POZ protein, SPOP, is involved in the DNA damage response
Zhang, D, Wang, H, Sun, M, Yang, J, Zhang, W, Han, S & Xu, B 2014, , Carcinogenesis, vol. 35, no. 8, pp. 1691-1697.

Activation of the ATM-Snail pathway promotes breast cancer metastasis
Sun, M, Guo, X, Qian, X, Wang, H, Yang, C, Brinkman, KL, Serrano-Gonzalez, M, Jope, RS, Zhou, B, Engler, DA, Zhan, M, Wong, STC, Fu, L & Xu, B 2012, , Journal of molecular cell biology, vol. 4, no. 5, pp. 304-315.

Strategies for targeting the DNA damage respones for cancer therapeutics
Zhang, D, Wang, HB, Brinkman, KL, Han, SX & Xu, B 2012, , Chinese journal of cancer, vol. 31, no. 8, pp. 359-363.

The kinetochore protein Bub1 participates in the DNA damage response
Yang, C, Wang, H, Xu, Y, Brinkman, KL, Ishiyama, H, Wong, STC & Xu, B 2012, , DNA Repair, vol. 11, no. 2, pp. 185-191.

CDK5RAP2 is required for spindle checkpoint function
Zhang, X, Liu, D, Lv, S, Wang, H, Zhong, X, Liu, B, Wang, B, Liao, J, Li, J, Pfeifer, GP & Xu, X 2009, , Cell Cycle, vol. 8, no. 8, pp. 1206-1216.

Human RIF1 encodes an anti-apoptotic factor required for DNA repair
Wang, H, Zhao, A, Chen, L, Zhong, X, Liao, J, Gao, M, Cai, M, Lee, DH, Li, J, Chowdhury, D, Yang, YG, Pfeifer, GP, Yen, Y & Xu, X 2009, , Carcinogenesis, vol. 30, no. 8, pp. 1314-1319.

Protein phosphatase PP4 is overexpressed in human breast and lung tumors
Wang, B, Zhao, A, Sun, L, Zhong, X, Zhong, J, Wang, H, Cai, M, Li, J, Xu, Y, Liao, J, Sang, J, Chowdhury, D, Pfeifer, GP, Yen, Y & Xu, X 2008, , Cell Research, vol. 18, no. 9, pp. 974-977.

Cloning and molecular characterization of three novel LMW-i glutenin subunit genes from cultivated einkorn (Triticum monococcum L.)
An, X, Zhang, Q, Yan, Y, Li, Q, Zhang, Y, Wang, A, Pei, Y, Tian, J, Wang, H, Hsam, SLK & Zeller, FJ 2006, , Theoretical and Applied Genetics, vol. 113, no. 3, pp. 383-395.