Zejuan Li lab Publications
Cell-free DNA 5-hydroxymethylcytosine is an emerging marker of acute myeloid leukemia
Shao, J, Wang, S, West-Szymanski, D, Karpus, J, Shah, S, Ganguly, S, Smith, J, Zu, Y, He, C & Li, Z 2022, , Scientific Reports, vol. 12, no. 1, 12410. https://doi.org/10.1038/s41598-022-16685-3
Revision of RUNX1 variant curation rules
the Myeloid Malignancy Variant Curation Expert Panel 2022, , Blood Advances, vol. 6, no. 16, pp. 4726-4730. https://doi.org/10.1182/bloodadvances.2022008017
Exome sequencing identifies PD-L2 as a potential predisposition gene for lymphoma
Shao, J, Gao, L, Leung, ML, Gallinger, B, Inglese, C, Meyn, MS, Del Gaudio, D, Das, S & Li, Z 2022, , Hematological Oncology, vol. 40, no. 3, pp. 475-478. https://doi.org/10.1002/hon.3033
Prognostic value of KIT and other clonal genetic mutations in core-binding factor acute myeloid leukemia
Wu, TM, Xue, SL, Li, Z, Yu, JQ, Wang, J, Wang, BR, Wan, CL, Shen, XD, Qiu, QC, Bao, XB & Wu, DP 2021, , Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, vol. 42, no. 8, pp. 646-653. https://doi.org/10.3760/cma.j.issn.0253-2727.2021.08.006
Prognostic value of KIT and other clonal genetic mutations in core-binding factor acute myeloid leukemia
Wu, TM, Xue, SL, Li, Z, Yu, JQ, Wang, J, Wang, BR, Wan, CL, Shen, XD, Qiu, QC, Bao, XB & Wu, DP 2021, , Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, vol. 42, no. 8, pp. 646-653. https://doi.org/10.3760/cma.j.issn.0253-2727.2021.08.006
R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis
Qing, Y, Dong, L, Gao, L, Li, C, Li, Y, Han, L, Prince, E, Tan, B, Deng, X, Wetzel, C, Shen, C, Gao, M, Chen, Z, Li, W, Zhang, B, Braas, D, ten Hoeve, J, Sanchez, GJ, Chen, H, Chan, LN, Chen, CW, Ann, D, Jiang, L, Müschen, M, Marcucci, G, Plas, DR, Li, Z, Su, R & Chen, J 2021, , Molecular Cell, vol. 81, no. 5, pp. 922-939.e9. https://doi.org/10.1016/j.molcel.2020.12.026
Identifying possible germline variants from tumor-only sequencing of hematological malignancies
Shao, J, Subedi, S, Pepper, K, Badgett, S, Christensen, PA, Hendrickson, HL, Thomas, JS, Olsen, RJ & Li, Z 2021, , Leukemia and Lymphoma, vol. 62, no. 2, pp. 482-485. https://doi.org/10.1080/10428194.2020.1832665
Germline variants drive myelodysplastic syndrome in young adults
Feurstein, S, Churpek, JE, Walsh, T, Keel, S, Hakkarainen, M, Schroeder, T, Germing, U, Geyh, S, Heuser, M, Thol, F, Pohlkamp, C, Haferlach, T, Gao, J, Owen, C, Goehring, G, Schlegelberger, B, Verma, D, Krause, DS, Gao, G, Cronin, T, Gulsuner, S, Lee, M, Pritchard, CC, Subramanian, HP, del Gaudio, D, Li, Z, Das, S, Kilpivaara, O, Wartiovaara-Kautto, U, Wang, ES, Griffiths, EA, Döhner, K, Döhner, H, King, MC & Godley, LA 2021, , Leukemia, vol. 35, no. 8, pp. 2439-2444. https://doi.org/10.1038/s41375-021-01137-0
Telomere biology disorder prevalence and phenotypes in adults with familial hematologic and/or pulmonary presentations
Feurstein, S, Adegunsoye, A, Mojsilovic, D, Vij, R, West DePersia, AH, Rajagopal, PS, Osman, A, Collins, RH, Kim, RH, Gore, SD, Greenberg, P, Godley, LA, Li, Z, Del Gaudio, D, Subramanian, HP, Das, S, Walsh, T, Gulsuner, S, Segal, JP, Husain, AN, Gurbuxani, S, King, MC, Strek, ME & Churpek, JE 2020, , Blood Advances, vol. 4, no. 19, pp. 4883-4886. https://doi.org/10.1182/BLOODADVANCES.2020001721
Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion
Su, R, Dong, L, Li, Y, Gao, M, Han, L, Wunderlich, M, Deng, X, Li, H, Huang, Y, Gao, L, Li, C, Zhao, Z, Robinson, S, Tan, B, Qing, Y, Qin, X, Prince, E, Xie, J, Qin, H, Li, W, Shen, C, Sun, J, Kulkarni, P, Weng, H, Huang, H, Chen, Z, Zhang, B, Wu, X, Olsen, MJ, Müschen, M, Marcucci, G, Salgia, R, Li, L, Fathi, AT, Li, Z, Mulloy, JC, Wei, M, Horne, D & Chen, J 2020, , Cancer Cell, vol. 38, no. 1, pp. 79-96.e11. https://doi.org/10.1016/j.ccell.2020.04.017
Development and validation of Houston Methodist Variant Viewer version 3: Updates to our application for interpretation of next-generation sequencing data
Christensen, PA, Subedi, S, Pepper, K, Hendrickson, HL, Li, Z, Thomas, JS, Wesley Long, S & Olsen, RJ 2020, , JAMIA Open, vol. 3, no. 2, pp. 299-305. https://doi.org/10.1093/jamiaopen/ooaa004
ClinGen Myeloid Malignancy Variant Curation Expert Panel recommendations for germline RUNX1 variants
Luo, X, Feurstein, S, Mohan, S, Porter, CC, Jackson, SA, Keel, S, Chicka, M, Brown, AL, Kesserwan, C, Agarwal, A, Luo, M, Li, Z, Ross, JE, Baliakas, P, Pineda-Alvarez, D, DiNardo, CD, Bertuch, AA, Mehta, N, Vulliamy, T, Wang, Y, Nichols, KE, Malcovati, L, Walsh, MF, Rawlings, LH, McWeeney, SK, Soulier, J, Raimbault, A, Routbort, MJ, Zhang, L, Ryan, G, Speck, NA, Plon, SE, Wu, D & Godley, LA 2019, , Blood Advances, vol. 3, no. 20, pp. 2962-2979. https://doi.org/10.1182/bloodadvances.2019000644
Somatic mutation panels: Time to clear their names
Trottier, AM, Cavalcante de Andrade Silva, M, Li, Z & Godley, LA 2019, , Cancer Genetics, vol. 235-236, pp. 84-92. https://doi.org/10.1016/j.cancergen.2019.04.065
Targeted exome analysis identifies the genetic basis of disease in over 50% of patients with a wide range of ataxia-related phenotypes
Sun, M, Johnson, AK, Nelakuditi, V, Guidugli, L, Fischer, D, Arndt, K, Ma, L, Sandford, E, Shakkottai, V, Boycott, K, Chardon, JW, Li, Z, del Gaudio, D, Burmeister, M, Gomez, CM, Waggoner, DJ & Das, S 2019, , Genetics in Medicine, vol. 21, no. 1, pp. 195-206. https://doi.org/10.1038/s41436-018-0007-7
Frequency of germline mutations in cancer susceptibility genes in malignant mesothelioma
Panou, V, Gadiraju, M, Wolin, A, Weipert, CM, Skarda, E, Husain, AN, Patel, JD, Rose, B, Zhang, SR, Weatherly, M, Nelakuditi, V, Johnson, AK, Helgeson, M, Fischer, D, Desai, A, Sulai, N, Ritterhouse, L, Røe, OD, Turaga, KK, Huo, D, Segal, J, Kadri, S, Li, Z, Kindler, HL & Churpek, JE 2018, , Journal of Clinical Oncology, vol. 36, no. 28, pp. 2863-2871. https://doi.org/10.1200/JCO.2018.78.5204
RNA N6-methyladenosine modification in cancers: current status and perspectives
Deng, X, Su, R, Weng, H, Huang, H, Li, Z & Chen, J 2018, , Cell Research, vol. 28, no. 5, pp. 507-517. https://doi.org/10.1038/s41422-018-0034-6
Erratum: Publisher Correction: miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia (Nature communications (2012) 3 (688))
Li, Z, Huang, H, Chen, P, He, M, Li, Y, Arnovitz, S, Jiang, X, He, C, Hyjek, E, Zhang, J, Zhang, Z, Elkahloun, A, Cao, D, Shen, C, Wunderlich, M, Wang, Y, Neilly, MB, Jin, J, Wei, M, Lu, J, Valk, PJM, Delwel, R, Lowenberg, B, Le Beau, MM, Vardiman, J, Mulloy, JC, Zeleznik-Le, NJ, Liu, PP, Zhang, J & Chen, J 2018, , Nature Communications, vol. 9, 16192, pp. 16192. https://doi.org/10.1038/ncomms16192
Molecular characterization of HDAC8 deletions in individuals with atypical Cornelia de Lange syndrome
Helgeson, M, Keller-Ramey, J, Knight Johnson, A, Lee, JA, Magner, DB, Deml, B, Deml, J, Hu, YY, Li, Z, Donato, K, Das, S, Laframboise, R, Tremblay, S, Krantz, I, Noon, S, Hoganson, G, Burton, J, Schaaf, CP & Del Gaudio, D 2018, , Journal of Human Genetics, vol. 63, no. 3, pp. 349-356. https://doi.org/10.1038/s10038-017-0387-6
Prognostic tumor sequencing panels frequently identify germ line variants associated with hereditary hematopoietic malignancies
Drazer, MW, Kadri, S, Sukhanova, M, Patil, SA, West, AH, Feurstein, S, Calderon, DA, Jones, MF, Weipert, CM, Daugherty, CK, Ceballos-Lopez, AA, Raca, G, Lingen, MW, Li, Z, Segal, JP, Churpek, JE & Godley, LA 2018, , Blood Advances, vol. 2, no. 2, pp. 146-150. https://doi.org/10.1182/bloodadvances.2017013037
Heterozygous RTEL1 variants in bone marrow failure and myeloid neoplasms
Marsh, JW, Gutierrez-Rodrigues, F, Cooper, J, Jiang, J, Gandhi, S, Kajigaya, S, Feng, X, Ibanez, MF, Donaires, FS, Da Silva, JPL, Li, Z, Das, S, Ibenez, M, Smith, AE, Lea, N, Best, S, Ireland, R, Kulasekararaj, AG, McLornan, DP, Pagliuca, A, Callebaut, I, Young, NS, Calado, RT, Townsley, DM & Mufti, GJ 2018, , Blood Advances, vol. 2, no. 1, pp. 36-48. https://doi.org/10.1182/bloodadvances.2017008110