Zejuan Li lab Publications


Prognostic value of KIT and other clonal genetic mutations in core-binding factor acute myeloid leukemia
Wu, TM, Xue, SL, Li, Z, Yu, JQ, Wang, J, Wang, BR, Wan, CL, Shen, XD, Qiu, QC, Bao, XB & Wu, DP 2021, , Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, vol. 42, no. 8, pp. 646-653. https://doi.org/10.3760/cma.j.issn.0253-2727.2021.08.006

R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis
Qing, Y, Dong, L, Gao, L, Li, C, Li, Y, Han, L, Prince, E, Tan, B, Deng, X, Wetzel, C, Shen, C, Gao, M, Chen, Z, Li, W, Zhang, B, Braas, D, ten Hoeve, J, Sanchez, GJ, Chen, H, Chan, LN, Chen, CW, Ann, D, Jiang, L, Müschen, M, Marcucci, G, Plas, DR, Li, Z, Su, R & Chen, J 2021, , Molecular Cell, vol. 81, no. 5, pp. 922-939.e9. https://doi.org/10.1016/j.molcel.2020.12.026

Identifying possible germline variants from tumor-only sequencing of hematological malignancies
Shao, J, Subedi, S, Pepper, K, Badgett, S, Christensen, PA, Hendrickson, HL, Thomas, JS, Olsen, RJ & Li, Z 2021, , Leukemia and Lymphoma, vol. 62, no. 2, pp. 482-485. https://doi.org/10.1080/10428194.2020.1832665

Germline variants drive myelodysplastic syndrome in young adults
Feurstein, S, Churpek, JE, Walsh, T, Keel, S, Hakkarainen, M, Schroeder, T, Germing, U, Geyh, S, Heuser, M, Thol, F, Pohlkamp, C, Haferlach, T, Gao, J, Owen, C, Goehring, G, Schlegelberger, B, Verma, D, Krause, DS, Gao, G, Cronin, T, Gulsuner, S, Lee, M, Pritchard, CC, Subramanian, HP, del Gaudio, D, Li, Z, Das, S, Kilpivaara, O, Wartiovaara-Kautto, U, Wang, ES, Griffiths, EA, Döhner, K, Döhner, H, King, MC & Godley, LA 2021, , Leukemia, vol. 35, no. 8, pp. 2439-2444. https://doi.org/10.1038/s41375-021-01137-0

Telomere biology disorder prevalence and phenotypes in adults with familial hematologic and/or pulmonary presentations
Feurstein, S, Adegunsoye, A, Mojsilovic, D, Vij, R, West DePersia, AH, Rajagopal, PS, Osman, A, Collins, RH, Kim, RH, Gore, SD, Greenberg, P, Godley, LA, Li, Z, Del Gaudio, D, Subramanian, HP, Das, S, Walsh, T, Gulsuner, S, Segal, JP, Husain, AN, Gurbuxani, S, King, MC, Strek, ME & Churpek, JE 2020, , Blood Advances, vol. 4, no. 19, pp. 4883-4886. https://doi.org/10.1182/BLOODADVANCES.2020001721

Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion
Su, R, Dong, L, Li, Y, Gao, M, Han, L, Wunderlich, M, Deng, X, Li, H, Huang, Y, Gao, L, Li, C, Zhao, Z, Robinson, S, Tan, B, Qing, Y, Qin, X, Prince, E, Xie, J, Qin, H, Li, W, Shen, C, Sun, J, Kulkarni, P, Weng, H, Huang, H, Chen, Z, Zhang, B, Wu, X, Olsen, MJ, Müschen, M, Marcucci, G, Salgia, R, Li, L, Fathi, AT, Li, Z, Mulloy, JC, Wei, M, Horne, D & Chen, J 2020, , Cancer Cell, vol. 38, no. 1, pp. 79-96.e11. https://doi.org/10.1016/j.ccell.2020.04.017

Development and validation of Houston Methodist Variant Viewer version 3: Updates to our application for interpretation of next-generation sequencing data
Christensen, PA, Subedi, S, Pepper, K, Hendrickson, HL, Li, Z, Thomas, JS, Wesley Long, S & Olsen, RJ 2020, , JAMIA Open, vol. 3, no. 2, pp. 299-305. https://doi.org/10.1093/jamiaopen/ooaa004

ClinGen Myeloid Malignancy Variant Curation Expert Panel recommendations for germline RUNX1 variants
Luo, X, Feurstein, S, Mohan, S, Porter, CC, Jackson, SA, Keel, S, Chicka, M, Brown, AL, Kesserwan, C, Agarwal, A, Luo, M, Li, Z, Ross, JE, Baliakas, P, Pineda-Alvarez, D, DiNardo, CD, Bertuch, AA, Mehta, N, Vulliamy, T, Wang, Y, Nichols, KE, Malcovati, L, Walsh, MF, Rawlings, LH, McWeeney, SK, Soulier, J, Raimbault, A, Routbort, MJ, Zhang, L, Ryan, G, Speck, NA, Plon, SE, Wu, D & Godley, LA 2019, , Blood Advances, vol. 3, no. 20, pp. 2962-2979. https://doi.org/10.1182/bloodadvances.2019000644

Somatic mutation panels: Time to clear their names
Trottier, AM, Cavalcante de Andrade Silva, M, Li, Z & Godley, LA 2019, , Cancer Genetics, vol. 235-236, pp. 84-92. https://doi.org/10.1016/j.cancergen.2019.04.065

Targeted exome analysis identifies the genetic basis of disease in over 50% of patients with a wide range of ataxia-related phenotypes
Sun, M, Johnson, AK, Nelakuditi, V, Guidugli, L, Fischer, D, Arndt, K, Ma, L, Sandford, E, Shakkottai, V, Boycott, K, Chardon, JW, Li, Z, del Gaudio, D, Burmeister, M, Gomez, CM, Waggoner, DJ & Das, S 2019, , Genetics in Medicine, vol. 21, no. 1, pp. 195-206. https://doi.org/10.1038/s41436-018-0007-7

Frequency of germline mutations in cancer susceptibility genes in malignant mesothelioma
Panou, V, Gadiraju, M, Wolin, A, Weipert, CM, Skarda, E, Husain, AN, Patel, JD, Rose, B, Zhang, SR, Weatherly, M, Nelakuditi, V, Johnson, AK, Helgeson, M, Fischer, D, Desai, A, Sulai, N, Ritterhouse, L, Røe, OD, Turaga, KK, Huo, D, Segal, J, Kadri, S, Li, Z, Kindler, HL & Churpek, JE 2018, , Journal of Clinical Oncology, vol. 36, no. 28, pp. 2863-2871. https://doi.org/10.1200/JCO.2018.78.5204

RNA N6-methyladenosine modification in cancers: current status and perspectives
Deng, X, Su, R, Weng, H, Huang, H, Li, Z & Chen, J 2018, , Cell Research, vol. 28, no. 5, pp. 507-517. https://doi.org/10.1038/s41422-018-0034-6

Erratum: Publisher Correction: miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia (Nature communications (2012) 3 (688))
Li, Z, Huang, H, Chen, P, He, M, Li, Y, Arnovitz, S, Jiang, X, He, C, Hyjek, E, Zhang, J, Zhang, Z, Elkahloun, A, Cao, D, Shen, C, Wunderlich, M, Wang, Y, Neilly, MB, Jin, J, Wei, M, Lu, J, Valk, PJM, Delwel, R, Lowenberg, B, Le Beau, MM, Vardiman, J, Mulloy, JC, Zeleznik-Le, NJ, Liu, PP, Zhang, J & Chen, J 2018, , Nature Communications, vol. 9, 16192, pp. 16192. https://doi.org/10.1038/ncomms16192

Molecular characterization of HDAC8 deletions in individuals with atypical Cornelia de Lange syndrome
Helgeson, M, Keller-Ramey, J, Knight Johnson, A, Lee, JA, Magner, DB, Deml, B, Deml, J, Hu, YY, Li, Z, Donato, K, Das, S, Laframboise, R, Tremblay, S, Krantz, I, Noon, S, Hoganson, G, Burton, J, Schaaf, CP & Del Gaudio, D 2018, , Journal of Human Genetics, vol. 63, no. 3, pp. 349-356. https://doi.org/10.1038/s10038-017-0387-6

Prognostic tumor sequencing panels frequently identify germ line variants associated with hereditary hematopoietic malignancies
Drazer, MW, Kadri, S, Sukhanova, M, Patil, SA, West, AH, Feurstein, S, Calderon, DA, Jones, MF, Weipert, CM, Daugherty, CK, Ceballos-Lopez, AA, Raca, G, Lingen, MW, Li, Z, Segal, JP, Churpek, JE & Godley, LA 2018, , Blood Advances, vol. 2, no. 2, pp. 146-150. https://doi.org/10.1182/bloodadvances.2017013037

Heterozygous RTEL1 variants in bone marrow failure and myeloid neoplasms
Marsh, JW, Gutierrez-Rodrigues, F, Cooper, J, Jiang, J, Gandhi, S, Kajigaya, S, Feng, X, Ibanez, MF, Donaires, FS, Da Silva, JPL, Li, Z, Das, S, Ibenez, M, Smith, AE, Lea, N, Best, S, Ireland, R, Kulasekararaj, AG, McLornan, DP, Pagliuca, A, Callebaut, I, Young, NS, Calado, RT, Townsley, DM & Mufti, GJ 2018, , Blood Advances, vol. 2, no. 1, pp. 36-48. https://doi.org/10.1182/bloodadvances.2017008110

Clinical utility of gene panel-based testing for hereditary myelodysplastic syndrome/acute leukemia predisposition syndromes
Guidugli, L, Johnson, AK, Alkorta-Aranburu, G, Nelakuditi, V, Arndt, K, Churpek, JE, Godley, LA, Townsley, D, Young, NS, Fitzpatrick, C, Del Gaudio, D, Das, S & Li, Z 2017, , Leukemia, vol. 31, no. 5, pp. 1226-1229. https://doi.org/10.1038/leu.2017.28

FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N 6 -Methyladenosine RNA Demethylase
Li, Z, Weng, H, Su, R, Weng, X, Zuo, Z, Li, C, Huang, H, Nachtergaele, S, Dong, L, Hu, C, Qin, X, Tang, L, Wang, Y, Hong, GM, Huang, H, Wang, X, Chen, P, Gurbuxani, S, Arnovitz, S, Li, Y, Li, S, Strong, J, Neilly, MB, Larson, RA, Jiang, X, Zhang, P, Jin, J, He, C & Chen, J 2017, , Cancer Cell, vol. 31, no. 1, pp. 127-141. https://doi.org/10.1016/j.ccell.2016.11.017

Eradication of acute myeloid leukemia with FLT3 ligand-targeted miR-150 nanoparticles
Jiang, X, Bugno, J, Hu, C, Yang, Y, Herold, T, Qi, J, Chen, P, Gurbuxani, S, Arnovitz, S, Strong, J, Ferchen, K, Ulrich, B, Weng, H, Wang, Y, Huang, H, Li, S, Neilly, MB, Larson, RA, Le Beau, MM, Bohlander, SK, Jin, J, Li, Z, Bradner, JE, Hong, S & Chen, J 2016, , Cancer research, vol. 76, no. 15, pp. 4470-4480. https://doi.org/10.1158/0008-5472.CAN-15-2949

Improved molecular diagnosis of patients with neonatal diabetes using a combined next-generation sequencing and MS-MLPA approach
Alkorta-Aranburu, G, Sukhanova, M, Carmody, D, Hoffman, T, Wysinger, L, Keller-Ramey, J, Li, Z, Johnson, AK, Kobiernicki, F, Botes, S, Fitzpatrick, C, Das, S & Del Gaudio, D 2016, , Journal of Pediatric Endocrinology and Metabolism, vol. 29, no. 5, pp. 523-531. https://doi.org/10.1515/jpem-2015-0341