Jerry D. Estep, MD

Associate Professor of Clinical Cardiology, Institute for Academic Medicine
Associate Clinical Member, Research Institute
Program Director, Advanced Heart Failure and Transplant Cardiology Fellowship, Department of Cardiology
Houston Methodist
Weill Cornell Medical College


Dr. Jerry Estep is the Medical Director of the Heart Transplant and LVAD Program at the Methodist DeBakey Heart & Vascular Center and JC Walter Jr. Transplant Center at The Houston Methodist Hospital in Houston, TX. As a staff member he has been actively involved in several multicenter trials including NHLBI (The National Heart, Lung, and Blood Institute) studies for patients with heart failure. His recent original work includes the evaluation of biomarkers and echo indices to facilitate the management and prognostication for patients with decompensated heart failure. Moreover, he is actively involved in research related to multimodality imaging to care for heart failure patients with LVAD’s. He has contributed to several published articles related to advanced heart failure, cardiac transplantation, and advanced treatments for amyloid cardiomyopathy. His recently published manuscripts appear in Circulation, Circulation Heart Failure, JACC, and JACC Imaging. He serves as peer review editor for Circulation, JACC, JASE, Journal of Cardiac Failure and The American Journal Transplantation. He has been recognized for his efforts and contributions and regularly presents at society meetings which include ACC, AHA, ASE, and ISHLT.

Description of Research

Dr. Estep conducts clinical trails of novel therapies and investigational new drugs in patients with decompensated heart failure and mechanical circulatory support/LVADS for heart failure.

Areas Of Expertise

Heart failure Mechanical circulatory support/LVADS for heart failure Investigational new drugs Heart transplant
Education & Training

, University of Texas Southwestern Medical Center
, Baylor College of Medicine

Caregivers of Patients With Left Ventricular Assist Devices: Possible Impacts on Patients' Mortality and Interagency Registry for Mechanically Assisted Circulatory Support-Defined Morbidity Events
Bruce, CR, Minard, CG, Wilhelms, LA, Abraham, M, Amione-Guerra, J, Pham, L, Grogan, SD, Trachtenberg, B, Smith, ML, Bruckner, BA, Estep, JD & Kostick, KM 2017, Circulation: Cardiovascular Quality and Outcomes, vol 10, no. 1. DOI:

Roads, Maps, and Destinations: the Journey of Left Ventricular Assist Device Implantation in Ambulatory Patients with Advanced Heart Failure
Trachtenberg, BH & Estep, JD 2016, Current Cardiology Reports, vol 18, no. 12, 132. DOI:

Role of multimodality imaging in patients with left ventricular assist device
Kassi, M & Estep, JD 2016, Current Opinion in Cardiology, vol 31, no. 5, pp. 510-522. DOI:

Deflation Timing Influences Intra-Aortic Balloon Pump-Mediated Carotid Blood Flow Reversal: A Case Report
Schutt, RC, Bhimiraj, A, Estep, JD, Guha, A, Trachtenberg, BH & Garami, Z 2016, Circulation: Heart Failure, vol 9, no. 9, 003474. DOI:

Deflation Timing Influences Intra-Aortic Balloon Pump-Mediated Carotid Blood Flow Reversal: A Case Report
Schutt, RC, Bhimiraj, A, Estep, JD, Guha, A, Trachtenberg, BH & Garami, Z 2016, Circulation. Heart failure, vol 9, no. 9. DOI:

Temporary Percutaneous Mechanical Circulatory Support in Advanced Heart Failure
Brown, JL & Estep, JD 2016, Heart Failure Clinics, vol 12, no. 3, pp. 385-398. DOI:

Total artificial heart implantation after excision of right ventricular angiosarcoma
Bruckner, BA, Abu Saleh, WK, Al Jabbari, O, Copeland, JG, Estep, JD, Loebe, M & Reardon, MJ 2016, Texas Heart Institute Journal, vol 43, no. 3, pp. 252-254. DOI:

Impact of Cytomegalovirus on Survival after Heart Transplant: Analysis of 20,000 Patients from the UNOS Registry Data
Ashrith, G, Daoud, A, Teeter, LD, Amione-Guerra, J, Cordero-Reyes, AM, Graviss, E, Trachtenberg, BH, Bhimaraj, A, Gaber, A, Scheinin, S, Torre-Amione, G & Estep, JD 2016, Journal of Heart and Lung Transplantation, vol 35, no. 4, pp. S60. DOI:

Development and validation of a patient-centered knowledge scale for left ventricular assist device placement
Kostick, KM, Minard, CG, Wilhelms, LA, Delgado, E, Abraham, M, Bruce, CR, Estep, JD, Loebe, M, Volk, RJ & Blumenthal-Barby, JS 2016, Journal of Heart and Lung Transplantation. DOI:

Full expression of cardiomyopathy is partly dependent on B-cells: A pathway that involves cytokine activation, immunoglobulin deposition, and activation of apoptosis
Cordero-Reyes, AM, Youker, KA, Trevino, AR, Celis, R, Hamilton, DJ, Flores-Arredondo, JH, Orrego, CM, Bhimaraj, A, Estep, JD & Torre-Amione, G 2016, Journal of the American Heart Association, vol 5, no. 1, pp. 1-12. DOI:

LVAD BTT Risk Score Predicts 1-Year Mortality in Patients Bridged to Transplant with a CF-Left Ventricular Assist Device (LVAD)
Guha, A, Nguyen, DTM, Amione-Guerra, J, Trachtenberg, B, Bhimaraj, A, Bruckner, B, Suarez, EE, Gaber, AO, Graviss, E, Park, MH & Estep, J 2016, International Society of Heart lung Transplantation , United States, 4/27/16 - 4/30/16, .

Impact of pre-operative coronary artery disease on cardiovascular events following lung transplantation
Chaikriangkrai, K, Jyothula, S, Jhun, HY, Estep, J, Loebe, M, Scheinin, S & Torre-Amione, G 2016, Journal of Heart and Lung Transplantation, vol 35, no. 1, pp. 115-121. DOI:

Is pump the answer to heart failure with preserved ejection fraction?
Guha, A & Estep, J 2016, JACC: Heart Failure, vol 4, no. 1, pp. 92-93. DOI:

Elevated Pressures on Aortic Valve Leaflets correlate with Orientation of LVAD Outflow Graft
Karmonik, C, Kassi, M, Bhimaraj, A, Estep, J, Loebe, M & Chang, S 2015, Journal of Cardiothoracic Surgery, vol 10 Suppl 1, pp. A356. DOI:

Risk assessment and comparative effectiveness of left ventricular assist device and medical management in ambulatory heart failure patients results from the ROADMAP Study
Estep, JD, Starling, RC, Horstmanshof, DA, Milano, CA, Selzman, CH, Shah, KB, Loebe, M, Moazami, N, Long, JW, Stehlik, J, Kasirajan, V, Haas, DC, OConnell, JB, Boyle, AJ, Farrar, DJ & Rogers, JG 2015, Journal of the American College of Cardiology, vol 66, no. 16, pp. 1747-1761. DOI:

Echocardiographic Identification of Acute Cellular Rejection in Heart Transplant Recipients
Estep, JD 2015, Journal of the American Society of Echocardiography, vol 28, no. 10, pp. 1157-1160. DOI:

Reasons why eligible candidates decline left ventricular assist device placement
Bruce, CR, Kostick, KM, Delgado, ED, Wilhelms, LA, Volk, RJ, Smith, ML, McCurdy, SA, Loebe, M, Estep, JD & Blumenthal-Barby, JS 2015, Journal of Cardiac Failure, vol 21, no. 10, pp. 835-839. DOI:

Assessment of patients' and caregivers' informational and decisional needs for left ventricular assist device placement: Implications for informed consent and shared decision-making
Blumenthal-Barby, JS, Kostick, KM, Delgado, ED, Volk, RJ, Kaplan, HM, Wilhelms, LA, McCurdy, SA, Estep, JD, Loebe, M & Bruce, CR 2015, Journal of Heart and Lung Transplantation, vol 34, no. 9, 6007, pp. 1182-1189. DOI:

Chronic heart failure: What does the horizon look like?
Estep, JD 2015, Current Opinion in Cardiology, vol 30, no. 4, pp. 344-353. DOI:

Echocardiography in the Management of Patients with Left Ventricular Assist Devices: Recommendations from the American Society of Echocardiography
Stainback, RF, Estep, JD, Agler, DA, Birks, EJ, Bremer, M, Hung, J, Kirkpatrick, JN, Rogers, JG & Shah, NR 2015, Journal of the American Society of Echocardiography, vol 28, no. 8, pp. 853-909. DOI: