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Guangjun Nie, PhD

Full Affiliate Member, Research Institute
Houston Methodist


Precision combination therapy for triple negative breast cancer via biomimetic polydopamine polymer core-shell nanostructures
Ding, Y, Su, S, Zhang, R, Shao, L, Zhang, Y, Wang, B, Li, Y, Chen, L, Yu, Q, Wu, Y & Nie, G 2017, Biomaterials, vol 113, pp. 243-252. DOI:

The regulation of iron metabolism by hepcidin contributes to unloading-induced bone loss
Xu, Z, Sun, W, Li, Y, Ling, S, Zhao, C, Zhong, G, Zhao, D, Song, J, Song, H, Li, J, You, L, Nie, G, Chang, Y & Li, Y 2017, Bone, vol 94, pp. 152-161. DOI:

Contiguous gene deletion in HFE2 region (1q21.1) and pathogenic HFE2 mutations in a Chinese hereditary hemochromatosis patient
Wang, Y, Du, Y, Liu, G, Guo, S, Yang, N, Hou, B, Jiang, X, Han, B, Chang, Y & Nie, G 2016, Gene Reports, vol 5, pp. 167-170. DOI:

Tie2 expression on macrophages is required for blood vessel reconstruction and tumor relapse after chemotherapy
Chen, L, Li, J, Wang, F, Dai, C, Wu, F, Liu, X, Li, T, Glauben, R, Zhang, Y, Nie, G, He, Y & Qin, Z 2016, Cancer Research, vol 76, no. 23, pp. 6828-6838. DOI:

Identification of novel mutations in HFE, HFE2, TfR2, and SLC40A1 genes in Chinese patients affected by hereditary hemochromatosis
Wang, Y, du, Y, Liu, G, Guo, S, Hou, B, Jiang, X, Han, B, Chang, Y & Nie, G 2016, International Journal of Hematology, pp. 1-5. DOI:

Qureshi, WA, Zhao, R, Wang, H, Ji, T, Ding, Y, Ihsan, A, Mujeeb, A, Nie, G & Zhao, Y 2016, Science Bulletin, pp. 1-10. DOI:

Analytical methods for nano-bio interface interactions
Wang, J, Quershi, WA, Li, Y, Xu, J & Nie, G 2016, Science China Chemistry, pp. 1-12. DOI:

Correlation of serum hepcidin levels with disease progression in hepatitis B virus-related disease assessed by nanopore film based assay
Wang, J, Dong, A, Liu, G, Anderson, GJ, Hu, TY, Shi, J, Hu, Y & Nie, G 2016, Scientific Reports, vol 6, 34252. DOI:

Identification of FECH gene multiple variations in two Chinese patients with erythropoietic protoporphyria and a review
Long, ZB, Wang, YW, Yang, C, Liu, G, Du, YL, Nie, GJ, Chang, YZ & Han, B 2016, Journal of Zhejiang University: Science B, vol 17, no. 10, pp. 813-820. DOI:

Metabolic Characteristics of 16HBE and A549 Cells Exposed to Different Surface Modified Gold Nanorods
Liu, Z, Wang, L, Zhang, L, Wu, X, Nie, G, Chen, C, Tang, H & Wang, Y 2016, Advanced Healthcare Materials, vol 5, no. 18, pp. 2363-2375. DOI:

Inducing enhanced immunogenic cell death with nanocarrier-based drug delivery systems for pancreatic cancer therapy
Zhao, X, Yang, K, Zhao, R, Ji, T, Wang, X, Yang, X, Zhang, Y, Cheng, K, Liu, S, Hao, J, Ren, H, Leong, KW & Nie, G 2016, Biomaterials, vol 102, pp. 187-197. DOI:

Role of cyclic alkyl group in conformational instability of tannase
Nie, G, Zhao, R, Sun, W, Gao, Y, Zhu, X, Zheng, Z & Yue, W 2016, Journal of Molecular Catalysis B: Enzymatic, vol 128, pp. 78-81. DOI:

Cancer cell-derived exosomes induce mitogen-activated protein kinase-dependent monocyte survival by transport of functional receptor tyrosine kinases
Song, X, Ding, Y, Liu, G, Yang, X, Zhao, R, Zhang, Y, Zhao, X, Anderson, GJ & Nie, G 2016, Journal of Biological Chemistry, vol 291, no. 16, pp. 8453-8464. DOI:

An MMP-2 responsive liposome integrating antifibrosis and chemotherapeutic drugs for enhanced drug perfusion and efficacy in pancreatic cancer
Ji, T, Li, S, Zhang, Y, Lang, J, Ding, Y, Zhao, X, Zhao, R, Li, Y, Shi, J, Hao, J, Zhao, Y & Nie, G 2016, ACS Applied Materials and Interfaces, vol 8, no. 5, pp. 3438-3445. DOI:

Aspect ratios of gold nanoshell capsules mediated melanoma ablation by synergistic photothermal therapy and chemotherapy
Wang, H, Zhao, R, Li, Y, Liu, H, Li, F, Zhao, Y & Nie, G 2016, Nanomedicine: Nanotechnology, Biology, and Medicine, vol 12, no. 2, pp. 439-448. DOI:

Integration of photothermal therapy and synergistic chemotherapy by a porphyrin self-assembled micelle confers chemosensitivity in triple-negative breast cancer
Su, S, Ding, Y, Li, Y, Wu, Y & Nie, G 2016, Biomaterials, vol 80, pp. 169-178. DOI:

Transformable peptide nanocarriers for expeditious drug release and effective cancer therapy via cancer-associated fibroblast activation
Zhao, Y, Ji, T, Zhao, Y, Ding, Y, Wang, J, Zhao, R, Lang, J, Qin, H, Liu, X, Shi, J, Tao, N, Qin, Z & Nie, G 2016, Angewandte Chemie - International Edition, vol 55, no. 3, pp. 1050-1055. DOI:

Functional Analysis of GLRX5 Mutants Reveals Distinct Functionalities of GLRX5 Protein
Liu, G, Wang, Y, Anderson, GJ, Camaschella, C, Chang, Y & Nie, G 2016, Journal of Cellular Biochemistry, vol 117, no. 1, pp. 207-217. DOI:

Synthesis and Characterization of Nontoxic Hollow Iron Oxide (Fe2O3) Nanoparticles Using a Simple Hydrothermal Strategy
Riasat, R & Nie, G 2016, Journal of Nanomaterials, vol 2016, 1920475. DOI:

Improvement of the in vitro safety profile and cytoprotective efficacy of amifostine against chemotherapy by PEGylation strategy
Yang, X, Ding, Y, Ji, T, Zhao, X, Wang, H, Zhao, X, Zhao, R, Wei, J, Qi, S & Nie, G 2015, Biochemical Pharmacology. DOI: