Nestor F. Esnaola, MD, MPH, MBA, FACS

Professor of Surgery, Academic Institute
Full Member, Research Institute
Associate Director, Cancer Control and Population Science, Dr. Mary and Ron Neal Cancer Center
Houston Methodist
Weill Cornell Medical College


Biography

Dr. Nestor Esnaola is division head of surgical oncology and gastrointestional surgery, Department of Surgery, Surgical Director, Houston Methodist Cancer Center, Associate Director, Cancer Control and Population Science, Katz Investigator, Houston Methodist Research Institute  

Description of Research

Dr. Esnaola will lead cancer center efforts in the areas of cancer prevention, community outreach and engagement, cancer health disparities, and population science research in accordance with NCI cancer center guidelines.

Publications

A phase II clinical trial of neoadjuvant sasanlimab and stereotactic body radiation therapy as an in situ vaccine for cisplatin-ineligible MIBC: The RAD VACCINE MIBC trial
Satkunasivam, R, Lim, K, Teh, BS, Guzman, J, Zhang, J, Farach, A, Chen, S-H, Wallis, CJD, Efstathiou, E, Esnaola, NF & Sonpavde, GP 2022, , Future Oncology, vol. 18, no. 25, pp. 2771-2781. https://doi.org/10.2217/fon-2022-0380

Early prediction of clinical response to checkpoint inhibitor therapy in human solid tumors through mathematical modeling
Butner, JD, Martin, GV, Wang, Z, Corradetti, B, Ferrari, M, Esnaola, N, Chung, C, Hong, DS, Welsh, JW, Hasegawa, N, Mittendorf, EA, Curley, SA, Chen, S-H, Pan, P-Y, Libutti, SK, Ganesan, S, Sidman, RL, Pasqualini, R, Arap, W, Koay, EJ & Cristini, V 2021, , eLife, vol. 10. https://doi.org/10.7554/eLife.70130

Early prediction of clinical response to checkpoint inhibitor therapy in human solid tumors through mathematical modeling
Butner, JD, Martin, GV, Wang, Z, Corradetti, B, Ferrari, M, Esnaola, N, Chung, C, Hong, DS, Welsh, JW, Hasegawa, N, Mittendorf, EA, Curley, SA, Chen, SH, Pan, PY, Libutti, SK, Ganesan, S, Sidman, RL, Pasqualini, R, Arap, W, Koay, EJ & Cristini, V 2021, , eLife, vol. 10, e70130. https://doi.org/10.7554/eLife.70130

Obesity affects outcomes of pancreatoduodenectomy
Zorbas, KA, Wu, J, Reddy, SS, Esnaola, NF & Karachristos, A 2021, , Pancreatology, vol. 21, no. 4, pp. 824-832. https://doi.org/10.1016/j.pan.2021.02.019

Atherosclerotic Cardiovascular Disease, Cancer, and Financial Toxicity Among Adults in the United States
Valero-Elizondo, J, Chouairi, F, Khera, R, Grandhi, GR, Saxena, A, Warraich, HJ, Virani, SS, Desai, NR, Sasangohar, F, Krumholz, HM, Esnaola, NF & Nasir, K 2021, , JACC: CardioOncology, vol. 3, no. 2, pp. 236-246. https://doi.org/10.1016/j.jaccao.2021.02.006

Effect of neighborhood and individual-level socioeconomic factors on colorectal cancer screening adherence
Mayhand, KN, Handorf, EA, Ortiz, AG, Gonzalez, ET, Devlin, A, Sorice, KA, Esnaola, N, Fisher, S & Lynch, SM 2021, , International journal of environmental research and public health, vol. 18, no. 9, 4398. https://doi.org/10.3390/ijerph18094398

Modified frailty index predicts complications and death after non-bariatric gastrectomies
Zorbas, KA, Velanovich, V, Esnaola, NF & Karachristos, A 2021, , Translational Gastroenterology and Hepatology, vol. 6, 5841. https://doi.org/10.21037/TGH.2020.01.07

Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma
Li, Z, Liu, H, He, J, Wang, Z, Yin, Z, You, G, Wang, Z, Davis, RE, Lin, P, Bergsagel, PL, Manasanch, EE, Wong, STC, Esnaola, NF, Chang, JC, Orlowski, RZ, Yi, Q & Yang, J 2021, , Cell Metabolism, vol. 33, no. 1, pp. 78-93.e7. https://doi.org/10.1016/j.cmet.2020.12.011

Perioperative Outcomes following Combined Versus Isolated Colorectal and Liver Resections: Insights from a Contemporary, National, Propensity Score-Based Analysis
Ward, WH, Hui, J, Davis, CH, Li, T, Goel, N, Handorf, E, Ross, EA, Curley, SA, Karachristos, A & Esnaola, NF 2021, , Annals of surgery. https://doi.org/10.1097/AS9.0000000000000050

Association of Surgeon-Patient Sex Concordance with Postoperative Outcomes
Wallis, CJD, Jerath, A, Coburn, N, Klaassen, Z, Luckenbaugh, AN, Magee, DE, Hird, AE, Armstrong, K, Ravi, B, Esnaola, NF, Guzman, JCA, Bass, B, Detsky, AS & Satkunasivam, R 2022, , JAMA Surgery, vol. 157, no. 2, pp. 146-156. https://doi.org/10.1001/jamasurg.2021.6339

The Effect of Discrimination on Likelihood of Participation in a Clinical Trial
Devlin, A, Gonzalez, E, Ramsey, F, Esnaola, N & Fisher, S 2020, , Journal of Racial and Ethnic Health Disparities, vol. 7, no. 6, pp. 1124-1129. https://doi.org/10.1007/s40615-020-00735-5

Early prediction of clinical response to checkpoint inhibitor therapy in human solid cancers through mathematical modeling
Butner, J, Martin, G, Wang, Z, Corradetti, B, Ferrari, M, Esnaola, NF, Chung, C, Hong, DS, Welsh, J, Mittendorf, EA, Curley, SA, Sidman, RL, Pasqualini, R, Arap, W, Koay, EJ & Cristini, V 2020, , JCO Precision Oncology.

Mathematical prediction of clinical outcomes in advanced cancer patients treated with checkpoint inhibitor immunotherapy
Butner, JD, Elganainy, D, Wang, CX, Wang, Z, Chen, SH, Esnaola, NF, Pasqualini, R, Arap, W, Hong, DS, Welsh, J, Koay, EJ & Cristini, V 2020, , Science advances, vol. 6, no. 18, eaay6298. https://doi.org/10.1126/sciadv.aay6298

Derivation of a cost-saving screening strategy for asymptomatic primary hyperparathyroidism
Nguyen-Lee, JJ, Paciuc, M, Guerra, R, Esnaola, N, Zanocco, KA & Zheng, F 2020, , Surgery (United States), vol. 167, no. 1, pp. 155-159. https://doi.org/10.1016/j.surg.2019.06.044

Preface
Ford, ME, Esnaola, NF & Salley, JD 2020, . in ME Ford, NF Esnaola & JD Salley (eds), Cancer Health Equity Research. Advances in Cancer Research, vol. 146, Academic Press, pp. xv-xx. https://doi.org/10.1016/S0065-230X(20)30030-0

BMI, physical activity, and breast cancer subtype in white, black, and Sea Island breast cancer survivors
Ford, ME, Bauza, CE, Findlay, VJ, Turner, DP, Abraham, LM, Moore, LA, Magwood, G, Alberg, AJ, Gaymon, K, Knight, KD, Hilton, E, Malek, AM, Kramer, RM, Peterson, LL, Gregoski, MJ, Bolick, S, Hurley, D, Mosley, C, Hazelton, TR, Burshell, DR, Nogueira, L, Mack, F, Brown, ET, Salley, JD, Whitfield, KE, Esnaola, NF & Cunningham, JE 2020, . in ME Ford, NF Esnaola & JD Salley (eds), Cancer Health Equity Research. Advances in Cancer Research, vol. 146, Academic Press, pp. 83-102. https://doi.org/10.1016/bs.acr.2020.01.005

Managing change
Uohara, MY, Ward, WH, Goel, N, Atchley, K & Esnaola, NF 2019, . in Quality in Obesity Treatment. Springer International Publishing, pp. 197-205. https://doi.org/10.1007/978-3-030-25173-4_21

US cancer centers of excellence strategies for increased inclusion of racial and ethnic minorities in clinical trials
Regnante, JM, Richie, NA, Fashoyin-Aje, L, Vichnin, M, Ford, M, Roy, UB, Turner, K, Hall, LL, Gonzalez, E, Esnaola, N, Clark, LT, Adams, HC, Alese, OB, Gogineni, K, McNeill, L, Petereit, D, Sargeant, I, Dang, J, Obasaju, C, Highsmith, Q, Lee, SC, Hoover, SC, Williams, EL & Chen, MS 2019, , Journal of oncology practice, vol. 15, no. 7, pp. E289-E299.

Does the Surgical Apgar Score predict serious complications after elective major cancer surgery?
Goel, N, Manstein, SM, Ward, WH, DeMora, L, Smaldone, MC, Farma, JM, Uzzo, RG & Esnaola, NF 2018, , Journal of Surgical Research, vol. 231, pp. 242-247. https://doi.org/10.1016/j.jss.2018.05.037

Concurrent chemoradiation for resected gall bladder cancers and cholangiocarcinomas
Fareed, MM, DeMora, L, Esnaola, NF, Denlinger, CS, Karachristos, A, Ross, EE, Hoffman, J & Meyer, JE 2018, , Journal of Gastrointestinal Oncology, vol. 9, no. 4, pp. 762-768. https://doi.org/10.21037/jgo.2018.05.09