Nestor F. Esnaola, MD, MPH, MBA, FACS

Hepatobiliary and Pancreatic Surgery, Surgical Oncology

Houston Methodist Department of Surgery

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Nestor F. Esnaola, MD, MPH, MBA, FACS

Houston Methodist Department of Surgery

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About Me

Although born in Caracas, Venezuela, Dr. Esnaola was raised in Houston, Texas. As a child, his pediatrician inspired him to become a physician. “Dr. Tovar was always thoughtful, kind, and compassionate. I knew from my interactions with him that he was the kind of individual I wanted to become, and that medicine was the career I wanted to pursue: one in which I would have the opportunity to help others and make things better".
As a medical student, Dr. Esnaola was always fascinated by cancer biology, but it wasn't until he spent time in the clinics and operating rooms that he truly understood the disruptive impact of cancer on patients' and families' lives. “Surgical oncologists aren’t simply surgeons that specialize in removing tumors. They have a deep knowledge of cancer that allow them to provide their patients with the best chance for cure and radically change their lives".
Dr. Esnaola's patient care philosophy is simple: "Always treat all your patients as you would like your own family to be treated". He added, “Working with cancer patients is a tremendous privilege. To be truly successful, Surgical Oncologists must collaborate closely with referring physicians and other cancer specialists to ensure that patients receive prompt, personalized, patient-centered, cutting-edge cancer care that addresses all their clinical, emotional, and social needs - from diagnosis to survivorship.”

Clinical Interests

Gastroesophageal Junction Cancer
Gastric Cancer (Stomach Mass)
Pancreatic Cancer (Mass)
Bile Duct Cancer (Stricture)
Gallbladder Cancer (Polyps/ Mass)
Small bowel Tumor (Mass)
Colon Cancer (Mass)
Rectal Cancer (Mass)
Liver tumor (Mass)

Accepted Insurance Plans

Aetna Affordable Health Choices
Aetna Choice POS / Open Choice
Aetna Common Spirit Health KelseyCare
Aetna Common Spirit Minimum Value Plan
Aetna CommonSpirit Health KelseyCare
Aetna EPO
Aetna HMO
Aetna Health Network
Aetna International
Aetna Managed Choice / Elect Choice
Aetna Medicare Advantage HMO
Aetna Medicare Advantage PPO
Aetna Meritain Health
Aetna Open Access
Aetna POS
Aetna PPO
Aetna QPOS
Aetna Select
Aetna Signature Administrators
Aetna Signature Administrators Allied Benefits
Aetna Signature Administrators CoreSource
Aetna Signature Administrators TX Annual Conf of UMC
Aetna Student Health
Aetna Transplant
Aetna Workers' Comp
All Saver/United Healthcare
Amerigroup STAR+PLUS Medicare-Medicaid Plan
Amerivantage Medicare Advantage
Amerivantage Medicare Advantage HMO-D-SNP
Beech Street PPO
Best Doctors International
Blue Choice POS
Blue Choice PPO
Blue Cross Blue Shield EPO
Blue Cross Blue Shield FEP Federal Employee Plan
Blue Cross Blue Shield Medicare Advantage HMO
Blue Cross Blue Shield Medicare Advantage PPO
Blue Cross Blue Shield POS
Blue Cross Blue Shield PPO
Blue Edge
Blue Essentials
Blue Essentials Access
Care Improvement Plus Medicare Advantage
Cigna APWU
Cigna Allegiance Houston Methodist Employee Medical Plan
Cigna Allegiance OAP
Cigna Allegiance PPO
Cigna Choice Fund
Cigna EPO
Cigna Global Health Benefits (International)
Cigna Great West
Cigna HMO
Cigna HealthSpring Medicare Advantage HMO
Cigna HealthSpring Medicare Advantage PPO
Cigna Indemnity
Cigna LocalPlus
Cigna NALC
Cigna Network
Cigna Network Open Access
Cigna Open Access
Cigna Open Access Plus (OAP)
Cigna POS
Cigna PPO
Cigna Qualcare
Cigna Shared Administration OAP
Cigna Shared Administration PPO
Cigna SureFit
Community Health Choice Marketplace-Silver & Gold
Community Health Choice Medicare Advantage HMO DSNP
Coventry PPO
Entrust/90 Degree EDI Payer ID# 36878
Erickson Advantage
Evolutions HealthCare PPO
First Health PPO
Galaxy Health Network PPO
HAA Preferred Partners (International)
HMO Blue
HealthSmart Accel PPO
HealthSmart PPO
HealthSmart Payors Organization
Humana HMO / EPO
Humana Medicare Advantage Choice PPO
Humana Medicare Advantage Gold Plus/Choice
Humana Medicare Advantage HMO
Humana Medicare Advantage PPO
Humana Military TRICARE-East Region
Humana Natl POS Open Access
Humana POS & Preferred POS
Humana PPO & Preferred PPO
Humana/ChoiceCare Network PPO
Humana/ChoiceCare+ Network PPO
Independent Medical Systems PPO (IMS)
Kelsey Seybold Affiliate Network
Medica-UnitedHealthcare Choice Plus
Medicare Railroad
Molina Dual Options StarPlus MMP
Molina Marketplace Exchange
Molina Medicare Complete Care HMO SNP
MultiPlan PPO
National Preferred Provider Network PPO (NPPN)
Olympus Managed Care (International)
Oscar Easy Care Medicare Advantage
PHCS Healthy Directions
ProCare Medicare Advantage
Provider Select PPO
TRS-ActiveCare 2 Group 385002
TRS-ActiveCare Fully Insured Plan-South Texas Region Group 295430
TRS-ActiveCare Fully Insured Plan-West Texas Region Group 295781
TRS-ActiveCare HD Group 385000
TRS-ActiveCare Primary Group 385003
TRS-ActiveCare Primary Plus Group 385001
TRS-Care Medicare Advantage
TRS-Care Standard ALT A I Group 485002
TRS-Care Standard ALT A II Group 485003
TRS-Care Standard ALT B I Group 485005
TRS-Care Standard ALT B II Group 485006
TRS-Care Standard CMED Group 485001
TRS-Care Standard Group 485000
TexanPlus/Wellcare Medicare Advantage
Three Rivers Provider Network
UHC Dual Complete MCR
UHC Medicare Chronic Complete
UHC Medicare Complete
UHC Medicare Solutions
US Family Health Plan
USA Managed Care PPO
United Health Integrated Services
United Healthcare Medicare Advantage
United Healthcare Nexus ACO
United Healthcare Plan of the River Valley
UnitedHealthcare Choice
UnitedHealthcare ChoicePlus
UnitedHealthcare Core
UnitedHealthcare Core Plus
UnitedHealthcare EPO
UnitedHealthcare Golden Rule
UnitedHealthcare HMO
UnitedHealthcare Navigate
UnitedHealthcare Navigate Plus
UnitedHealthcare Options PPO
UnitedHealthcare Oxford
UnitedHealthcare POS
UnitedHealthcare PPO
UnitedHealthcare Select / ERS
UnitedHealthcare Student Resources
UnitedHealthcare West
WellMed AARP Medicare Advantage Plan
WellMed AARP Medicare Complete
WellMed United Healthcare Dual Complete

Insurance plans may change. Please verify your plan is accepted when scheduling an appointment.


Surgical Oncology | University of Texas MD Anderson Cancer Center, Houston, Texas | 2003
General Surgery | American Board of Surgery | 2001
Surgical Oncology | University of Texas MD Anderson Cancer Center, Houston, Texas | 2001
Transplantation Biology | Massachusetts General Hospital | 1997
General Surgery | Brigham and Women’s Hospital / Harvard Medical School, Boston, Massachusetts | 2000
Public Health | Harvard School of Public Health, Boston, Massachusetts | 1998
Johns Hopkins University, Baltimore, Maryland | 1993
Biochemistry, Art & Art History | Rice University, Houston, Texas | 1989
  • Houston Methodist Hospital
  • Houston Methodist Lynda K. & David M. Underwood Center for Digestive Disorders
  • Houston Methodist Dr. Mary and Ron Neal Cancer Center


  • English
  • Spanish
Languages listed are spoken by doctor and/or office staff.

Frequently Asked Questions

  • Can I make an appointment with Dr. Nestor F. Esnaola online?
    Yes, you can schedule an appointment with Dr. Nestor F. Esnaola by visiting this page.
  • What insurance does Dr. Nestor F. Esnaola accept?
    See the insurance that Dr. Nestor F. Esnaola accepts here.
  • Where is Dr. Nestor F. Esnaola located?
    Dr. Nestor F. Esnaola sees patients at the following locations:
    • Smith Tower, 6550 Fannin St., Ste 1501, Houston, TX 77030
  • What languages do Dr. Nestor F. Esnaola and/or staff speak?
    Dr. Nestor F. Esnaola and/or office staff speak English and Spanish