Junji Xing

Junji Xing, PhD

Assistant Research Professor of Immunology in Surgery, Academic Institute
Assistant Research Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Immunobiology & Transplant Science Center


jxing@houstonmethodist.org
Education & Training

PhD, Graduate University of Chinese Academy of Sciences
Publications

Loss of TRIM29 mitigates viral myocarditis by attenuating PERK-driven ER stress response in male mice
Wang, J, Lu, W, Zhang, J, Du, Y, Fang, M, Zhang, A, Sungcad, G, Chon, S & Xing, J 2024, , Nature Communications, vol. 15, no. 1, 3481. https://doi.org/10.1038/s41467-024-44745-x

Loss of TRIM29 mitigates viral myocarditis by attenuating PERK-driven ER stress response in male mice
Wang, J, Lu, W, Zhang, J, Du, Y, Fang, M, Zhang, A, Sungcad, G, Chon, S & Xing, J 2024, , Nature Communications, vol. 15, no. 1, 3481, pp. 3481. https://doi.org/10.1038/s41467-024-44745-x

Editorial: Antiviral innate immune sensing, regulation, and viral immune evasion
Lu, W, Wang, L & Xing, J 2024, , Frontiers in immunology, vol. 14, 1358542, pp. 1358542. https://doi.org/10.3389/fimmu.2023.1358542

Editorial: Community series in antiviral innate immune sensing, regulation, and viral immune evasion: volume II
Wang, L & Xing, J 2023, , Frontiers in immunology, vol. 14, 1341193, pp. 1341193. https://doi.org/10.3389/fimmu.2023.1341193

TRIM29 Causes Pathogenesis of Viral Myocarditis by Inducing PERK-Mediated Endoplasmic Reticulum Stress and Reactive Oxygen Species Responses
Lu, W, Wang, J, Zhang, J, Du, Y, Fang, M, Zhang, A, Sungcad, G, Chon, S & Xing, J 2023, , American Heart Association 2023, 11/11/23 - 11/13/23 pp. Circulation, 148 (Suppl_1), A13301-A13301.

Species-specific cleavage of cGAS by picornavirus protease 3C disrupts mitochondria DNA-mediated immune sensing
Yan, Y, Wu, L, Yuan, Y, Wang, H, Yin, H, Li, M, Chai, L, Liang, R, Liu, Y, Zhao, D, Xing, J, Li, P & Li, X 2023, , PLoS pathogens, vol. 19, no. 9, e1011641, pp. e1011641. https://doi.org/10.1371/journal.ppat.1011641

Trim29 Deficiency Ameliorates Viral Myocarditis By Reducing Perk Mediated Er Stress And Ros Responses
Wang, J, Lu, W, Du, Y, Zhang, J, Minze, L & Xing, J 2023, , Basic Cardiovascular Sciences Scientific Sessions 2023, Boston, United States, 7/31/23 - 8/3/23 pp. Circulation Research, 133 (Suppl_1), AP3083-AP3083. <https://www.ahajournals.org/doi/abs/10.1161/res.133.suppl_1.P3083>

Editorial: Plasticity and metabolic switching in adipose tissue macrophages
Zhang, J & Xing, J 2023, , Frontiers in immunology, vol. 14, pp. 1233791. https://doi.org/10.3389/fimmu.2023.1233791

TRIM56 coiled-coil domain structure provides insights into its E3 ligase functions
Lou, X, Ma, B, Zhuang, Y, Xiao, X, Minze, LJ, Xing, J, Zhang, Z & Li, XC 2023, , Computational and Structural Biotechnology Journal, vol. 21, pp. 2801-2808. https://doi.org/10.1016/j.csbj.2023.04.022

Apex1 controls the systemic lupus erythematosus development
Du, Y, Xing, J, Yuan, R, Fang, M, Lu, W & Zhang, Z 2023, , The 3rd Annual GCC Future of Immunology Symposium, Houston, United States, 3/7/23 - 3/8/23.

Structural studies of the coiled-coil domain of TRIM75 reveal a tetramer architecture facilitating its E3 ligase complex
Lou, X, Ma, B, Zhuang, Y, Xiao, X, Minze, LJ, Xing, J, Zhang, Z & Li, XC 2022, , Computational and Structural Biotechnology Journal, vol. 20, pp. 4921-4929. https://doi.org/10.1016/j.csbj.2022.08.069, https://doi.org/10.1016/j.csbj.2022.08.069

TRIM18 is a critical regulator of viral myocarditis and organ inflammation
Fang, M, Zhang, A, Du, Y, Lu, W, Wang, J, Minze, LJ, Cox, TC, Li, XC, Xing, J & Zhang, Z 2022, , Journal of Biomedical Science, vol. 29, no. 1, 55. https://doi.org/10.1186/s12929-022-00840-z

TRIM18 is a critical regulator of viral myocarditis and organ inflammation
Fang, M, Zhang, A, Du, Y, Lu, W, Wang, J, Minze, LJ, Cox, TC, Li, XC, Xing, J & Zhang, Z 2022, , Journal of Biomedical Science, vol. 29, no. 1, 55, pp. 55. https://doi.org/10.1186/s12929-022-00840-z

Mechanisms involved in controlling RNA virus-induced intestinal inflammation
Zhang, E, Fang, M, Jones, C, Minze, LJ, Xing, J & Zhang, Z 2022, , Cellular and Molecular Life Sciences, vol. 79, no. 6, 313, pp. 313. https://doi.org/10.1007/s00018-022-04332-z, https://doi.org/10.1007/s00018-022-04332-z

Mechanisms involved in controlling RNA virus-induced intestinal inflammation
Zhang, E, Fang, M, Jones, C, Minze, LJ, Xing, J & Zhang, Z 2022, , Cellular and Molecular Life Sciences, vol. 79, no. 6, 313. https://doi.org/10.1007/s00018-022-04332-z

Structural studies of the coiled-coil domain of TRIM75 reveal a tetramer architecture facilitating its E3 ligase complex
Lou, X, Ma, B, Zhuang, Y, Xiao, X, Minze, LJ, Xing, J, Zhang, Z & Li, XC 2022, , Computational and Structural Biotechnology Journal, vol. 20, pp. 4921-4929. https://doi.org/10.1016/j.csbj.2022.08.069

Midline1 is a Critical Regulator of Viral Myocarditis
Xing, J, Fang, M, Lu, W, Wang, J & Zhang, Z 2022, .

IDENTIFICATION OF MIDLINE1 AS A CHECKPOINT REGULATOR IN ANTIVIRAL INNATE IMMUNITY
Xing, J, Fang, M & Zhang, Z 2022, .

Editorial: Sensing DNA in Antiviral Innate Immunity
Lin, R, Xing, J & Zheng, C 2021, , Frontiers in immunology, vol. 12, 644310, pp. 644310. https://doi.org/10.3389/fimmu.2021.644310

DHX15 is required to control RNA virus-induced intestinal inflammation
Xing, J, Zhou, X, Fang, M, Zhang, E, Minze, LJ & Zhang, Z 2021, , Cell Reports, vol. 35, no. 12, 109205, pp. 109205. https://doi.org/10.1016/j.celrep.2021.109205

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