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Francesca Taraballi, PhD

Assistant Professor of Orthopedic Surgery, Institute for Academic Medicine
Assistant Member, Research Institute
Houston Methodist


ftaraballi2@houstonmethodist.org
Biography

Dr. Taraballi earned her B.S. in Biological Sciences and her M.S. in Biochemistry at University of Milan - Bicocca, Italy and a Ph.D. in Nanostructures and Nanotechnologies from a joint program of the Materials Science Department of University of Milan - Bicocca with the Lawrence National Berkeley Laboratory (LBNL) in 2009. Her research focused on tissue engineering for different applications (spinal cord injury, cardiovascular, musculoskeletal). In January 2013, she joined the Houston Methodist Research Institute as Research Associate in the Center for Biomimetic Medicine.

Description of Research

Dr. Taraballi's research is focused on
• materials' functionalization to promote cells' survival and differentiation in cartilage repair
• development of smart biomaterials to tune the immunesystems
• synthesis and functionalization of micro and nanoparticles for immunemodulation
• synthesis and functionalization of nanoparticles for targeted cancer drug delivery

Publications

Electrospun Patch Functionalized with Nanoparticles Allows for Spatiotemporal Release of VEGF and PDGF-BB Promoting in Vivo Neovascularization
Tsao, CJ, Pandolfi, L, Wang, X, Minardi, S, Lupo, C, Evangelopoulos, M, Hendrickson, T, Shi, A, Storci, G, Taraballi, F & Tasciotti, E 2018, ACS Applied Materials and Interfaces, vol. 10, no. 51, pp. 44344-44353. https://doi.org/10.1021/acsami.8b19975

Controlled release of small molecules for cardiac differentiation of pluripotent stem cells
Tsao, C, Taraballi, F, Pandolfi, L, Velasquez-Mao, AJ, Ruano, R, Tasciotti, E & Jacot, JG 2018, Tissue Engineering - Part A, vol. 24, no. 23-24, pp. 1798-1807. https://doi.org/10.1089/ten.TEA.2018.0054, https://doi.org/10.1089/ten.tea.2018.0054

Corrigendum: Heparan sulfate: A potential candidate for the development of biomimetic immunomodulatory membranes [Front. Bioeng. Biotechnol, 5, (2017), (54)] DOI:10.3389/fbioe.2017.00054
Corradetti, B, Taraballi, F, Giretti, I, Bauza, G, Pistillo, RS, Niclot, FB, Pandolfi, L, Demarchi, D & Tasciotti, E 2018, Frontiers in Bioengineering and Biotechnology, vol. 5, no. JAN, 86. https://doi.org/10.3389/fbioe.2017.00086

Biomimetic Tissue Engineering: Tuning the Immune and Inflammatory Response to Implantable Biomaterials
Taraballi, F, Sushnitha, M, Tsao, C, Bauza, G, Liverani, C, Shi, A & Tasciotti, E 2018, Advanced Healthcare Materials. https://doi.org/10.1002/adhm.201800490

Design and Development of Biomimetic Nanovesicles Using a Microfluidic Approach
Molinaro, R, Evangelopoulos, M, Hoffman, JR, Corbo, C, Taraballi, F, Martinez, JO, Hartman, KA, Cosco, D, Costa, G, Romeo, I, Sherman, M, Paolino, D, Alcaro, S & Tasciotti, E 2018, Advanced Materials. https://doi.org/10.1002/adma.201702749

Concise Review: Biomimetic Functionalization of Biomaterials to Stimulate the Endogenous Healing Process of Cartilage and Bone Tissue
Taraballi, F, Bauza, G, McCulloch, P, Harris, J & Tasciotti, E 2017, Stem Cells Translational Medicine, vol. 6, no. 12, pp. 2186-2196. https://doi.org/10.1002/sctm.17-0181

Immune tuning scaffold for the local induction of a pro-regenerative environment
Corradetti, B, Taraballi, F, Corbo, C, Cabrera, F, Pandolfi, L, Minardi, S, Wang, X, Van Eps, J, Bauza, G, Weiner, B & Tasciotti, E 2017, Scientific Reports, vol. 7, no. 1, 17030. https://doi.org/10.1038/s41598-017-16895-0

Hyaluronic acid coatings as a simple and efficient approach to improve MSC homing toward the site of inflammation
Corradetti, B, Taraballi, F, Martinez, JO, Minardi, S, Basu, N, Bauza, G, Evangelopoulos, M, Powell, S, Corbo, C & Tasciotti, E 2017, Scientific Reports, vol. 7, no. 1, 7991, pp. 7991. https://doi.org/10.1038/s41598-017-08687-3

Mesoporous silica nanoparticles trigger mitophagy in endothelial cells and perturb neuronal network activity in a size- and time-dependent manner
Orlando, A, Cazzaniga, EM, Tringali, M, Gullo, F, Becchetti, A, Minniti, S, Taraballi, F, Tasciotti, E & Re, F 2017, International journal of nanomedicine, vol. 12, pp. 3547-3559. https://doi.org/10.2147/IJN.S127663

Enhancing Vascularization through the Controlled Release of Platelet-Derived Growth Factor-BB
Minardi, S, Pandolfi, L, Taraballi, F, Wang, X, De Rosa, E, Mills, ZD, Liu, X, Ferrari, M & Tasciotti, E 2017, ACS Applied Materials and Interfaces, vol. 9, no. 17, pp. 14566-14575. https://doi.org/10.1021/acsami.6b13760

The viral protein gp120 decreases the acetylation of neuronal tubulin: potential mechanism of neurotoxicity
Avdoshina, V, Caragher, SP, Wenzel, ED, Taraballi, F, Mocchetti, I & Harry, GJ 2017, Journal of Neurochemistry, vol. 141, no. 4, pp. 606-613. https://doi.org/10.1111/jnc.14015

Unveiling the in Vivo Protein Corona of Circulating Leukocyte-like Carriers
Corbo, C, Molinaro, R, Taraballi, F, Toledano Furman, NE, Hartman, KA, Sherman, MB, De Rosa, E, Kirui, DK, Salvatore, F & Tasciotti, E 2017, ACS Nano, vol. 11, no. 3, pp. 3262-3273. https://doi.org/10.1021/acsnano.7b00376

Endocytic Trafficking of HIV gp120 is Mediated by Dynamin and Plays a Role in gp120 Neurotoxicity
Wenzel, ED, Bachis, A, Avdoshina, V, Taraballi, F, Tasciotti, E & Mocchetti, I 2017, Journal of Neuroimmune Pharmacology, pp. 1-12. https://doi.org/10.1007/s11481-017-9739-4

A nanofibrous electrospun patch to maintain human mesenchymal cell stemness
Pandolfi, L, Furman, NT, Wang, X, Lupo, C, Martinez, JO, Mohamed, M, Taraballi, F & Tasciotti, E 2017, Journal of Materials Science: Materials in Medicine, vol. 28, no. 3, 44, pp. 44. https://doi.org/10.1007/s10856-017-5856-0

Heparan Sulfate: A Potential Candidate for the Development of Biomimetic Immunomodulatory Membranes
Corradetti, B, Taraballi, F, Giretti, I, Bauza, G, Pistillo, RS, Banche Niclot, F, Pandolfi, L & Tasciotti, E 2017, Frontiers in Bioengineering and Biotechnology, vol. 5, pp. 54. https://doi.org/10.3389/fbioe.2017.00054

Trizonal membranes for periosteum regeneration
Taraballi, F 2017, .

Nanocomposites: Nanocomposite Hydrogels as Platform for Cells Growth, Proliferation, and Chemotaxis (Small 35/2016)
Fiorini, F, Prasetyanto, EA, Taraballi, F, Pandolfi, L, Monroy, F, López-Montero, I, Tasciotti, E & De Cola, L 2016, Small, vol. 12, no. 35, pp. 4910. https://doi.org/10.1002/smll.201670179

Biomimetic collagen/elastin meshes for ventral hernia repair in a rat model
Minardi, S, Taraballi, F, Wang, X, Cabrera, FJ, Van Eps, JL, Robbins, AB, Sandri, M, Moreno, MR, Weiner, BK & Tasciotti, E 2016, Acta Biomaterialia. https://doi.org/10.1016/j.actbio.2016.11.032

Effects of the protein corona on liposome-liposome and liposome-cell interactions
Corbo, C, Molinaro, R, Taraballi, F, Toledano Furman, NE, Sherman, MB, Parodi, A, Salvatore, F & Tasciotti, E 2016, International journal of nanomedicine, vol. 11, pp. 3049-3063. https://doi.org/10.2147/IJN.S109059

“Biomimetic Materials to target inflammation toward regeneration.
Taraballi, F 2016, Biomimetic Materials to target inflammation toward regeneration.