Zu lab Publications


A novel role of lysophosphatidic acid (LPA) in human myeloma resistance to proteasome inhibitors
Su, P, Xiao, L, Ye, L, Wang, Z, Xiong, W, Wang, Q, Ma, X, Xian, M, Yang, M, Zu, Y, Pingali, SR, Qian, J & Yi, Q 2022, , Journal of Hematology and Oncology, vol. 15, no. 1, 55. https://doi.org/10.1186/s13045-022-01269-5

MYCN-driven fatty acid uptake is a metabolic vulnerability in neuroblastoma
Tao, L, Mohammad, MA, Milazzo, G, Moreno-Smith, M, Patel, TD, Zorman, B, Badachhape, A, Hernandez, BE, Wolf, AB, Zeng, Z, Foster, JH, Aloisi, S, Sumazin, P, Zu, Y, Hicks, J, Ghaghada, KB, Putluri, N, Perini, G, Coarfa, C & Barbieri, E 2022, , Nature Communications, vol. 13, no. 1, 3728. https://doi.org/10.1038/s41467-022-31331-2

Cell-free DNA 5-hydroxymethylcytosine is an emerging marker of acute myeloid leukemia
Shao, J, Wang, S, West-Szymanski, D, Karpus, J, Shah, S, Ganguly, S, Smith, J, Zu, Y, He, C & Li, Z 2022, , Scientific Reports, vol. 12, no. 1, 12410. https://doi.org/10.1038/s41598-022-16685-3

Aptamer–Gemcitabine Conjugates with Enzymatically Cleavable Linker for Targeted Delivery and Intracellular Drug Release in Cancer Cells
Qi, J, Zeng, Z, Chen, Z, Nipper, C, Liu, X, Wan, Q, Chen, J, Tung, CH & Zu, Y 2022, , Pharmaceuticals, vol. 15, no. 5, 558. https://doi.org/10.3390/ph15050558

Genetic Subtyping and Phenotypic Characterization of the Immune Microenvironment and MYC/BCL2 Double Expression Reveal Heterogeneity in Diffuse Large B-cell Lymphoma
Xu-Monette, ZY, Wei, L, Fang, X, Au, Q, Nunns, H, Nagy, M, Tzankov, A, Zhu, F, Visco, C, Bhagat, G, Dybkaer, K, Chiu, A, Tam, W, Zu, Y, Hsi, ED, Hagemeister, FB, Sun, X, Han, X, Go, H, Ponzoni, M, Ferreri, AJM, Møller, MB, Parsons, BM, van Krieken, JH, Piris, MA, Winter, JN, Li, Y, Xu, B, Albitar, M, You, H & Young, KH 2022, , Clinical Cancer Research, vol. 28, no. 5, pp. 972-983. https://doi.org/10.1158/1078-0432.CCR-21-2949

Aptamer Targets Triple-Negative Breast Cancer through Specific Binding to Surface CD49c
Wan, Q, Zeng, Z, Qi, J, Zhao, Y, Liu, X, Chen, Z, Zhou, H & Zu, Y 2022, , Cancers, vol. 14, no. 6, 1570. https://doi.org/10.3390/cancers14061570

Next-Generation Sequencing Revealed a Distinct Immunoglobulin Repertoire with Specific Mutation Hotspots in Acute Myeloid Leukemia
Xia, M, Wu, L, Sun, X, Han, X, Yan, H, Huang, J, Zhang, Y, Hu, Z, Zu, Y, Yin, CC & Qiu, X 2022, , Biology, vol. 11, no. 2, 161. https://doi.org/10.3390/biology11020161

Determining clinical course of diffuse large B-cell lymphoma using targeted transcriptome and machine learning algorithms
Albitar, M, Zhang, H, Goy, A, Xu-Monette, ZY, Bhagat, G, Visco, C, Tzankov, A, Fang, X, Zhu, F, Dybkaer, K, Chiu, A, Tam, W, Zu, Y, Hsi, ED, Hagemeister, FB, Huh, J, Ponzoni, M, Ferreri, AJM, Møller, MB, Parsons, BM, van Krieken, JH, Piris, MA, Winter, JN, Li, Y, Xu, B & Young, KH 2022, , Blood Cancer Journal, vol. 12, no. 2, 25. https://doi.org/10.1038/s41408-022-00617-5

RAR? activation sensitizes human myeloma cells to carfilzomib treatment through the OAS-RNase L innate immune pathway
Wang, Q, Lin, Z, Wang, Z, Ye, L, Xian, M, Xiao, L, Su, P, Bi, E, Huang, YH, Qian, J, Liu, L, Ma, X, Yang, M, Xiong, W, Zu, Y, Pingali, SR, Xu, B & Yi, Q 2022, , Blood, vol. 139, no. 1, pp. 59-72. https://doi.org/10.1182/blood.2020009856

Aptamer-armed nanostructures improve the chemotherapy outcome of triple-negative breast cancer
Wan, Q, Zeng, Z, Qi, J, Chen, Z, Liu, X & Zu, Y 2022, , Molecular Therapy, vol. 30, no. 6, pp. 2242-2256. https://doi.org/10.1016/j.ymthe.2022.02.004

Poor Humoral Response in Solid Organ Transplant Recipients Following Complete mRNA SARS-CoV-2 Vaccination
Cao, J, Liu, X, Muthukumar, A, Gagan, J, Jones, P & Zu, Y 2022, , Clinical Chemistry, vol. 68, no. 1, pp. 251-253. https://doi.org/10.1093/clinchem/hvab149

RAR? activation sensitizes human myeloma cells to carfilzomib treatment through OAS-RNase L innate immune pathway
Wang, Q, Lin, Z, Wang, Z, Ye, L, Xian, M, Xiao, L, Su, P, Bi, E, Huang, Y-H, Qian, J, Liu, L, Ma, X, Yang, M, Xiong, W, Zu, Y, Pingali, SR, Xu, B & Yi, Q 2021, , Blood. https://doi.org/10.1182/blood.2020009856


EpCAM-Targeting Aptamer Radiotracer for Tumor-Specific PET Imaging
Li, F, Zeng, Z, Hamilton, D, Zu, Y & Li, Z 2021, , Bioconjugate chemistry, vol. 32, no. 6, pp. 1139-1145. https://doi.org/10.1021/acs.bioconjchem.1c00188

Author Correction: ALK phosphorylates SMAD4 on tyrosine to disable TGF-ß tumour suppressor functions (Nature Cell Biology, (2019), 21, 2, (179-189), 10.1038/s41556-018-0264-3)
Zhang, Q, Xiao, M, Gu, S, Xu, Y, Liu, T, Li, H, Yu, Y, Qin, L, Zhu, Y, Chen, F, Wang, Y, Ding, C, Wu, H, Ji, H, Chen, Z, Zu, Y, Malkoski, S, Li, Y, Liang, T, Ji, J, Qin, J, Xu, P, Zhao, B, Shen, L, Lin, X & Feng, XH 2021, , Nature Cell Biology, vol. 23, no. 3, pp. 293. https://doi.org/10.1038/s41556-021-00638-5

Aggressive B-cell lymphoma with MYC/TP53 dual alterations displays distinct clinicopathobiological features and response to novel targeted agents
Deng, M, Xu-Monette, ZY, Pham, LV, Wang, X, Tzankov, A, Fang, X, Zhu, F, Visco, C, Bhagat, G, Dybkaer, K, Chiu, A, Tam, W, Zu, Y, Hsi, ED, You, H, Huh, J, Ponzoni, M, Ferreri, AJM, Møller, MB, Parsons, BM, Hagemeister, F, van Krieken, JH, Piris, MA, Winter, JN, Li, Y, Xu, B, Liu, P & Young, KH 2021, , Molecular Cancer Research, vol. 19, no. 2, pp. 249-260. https://doi.org/10.1158/1541-7786.MCR-20-0466

G6PD deficiency and severity of COVID19 pneumonia and acute respiratory distress syndrome: tip of the iceberg?
Youssef, JG, Zahiruddin, F, Youssef, G, Padmanabhan, S, Ensor, J, Pingali, SR, Zu, Y, Sahay, S & Iyer, SP 2021, , Annals of Hematology, vol. 100, no. 3, pp. 667-673. https://doi.org/10.1007/s00277-021-04395-1

Neutralizing Aptamers Block S/RBD-ACE2 Interactions and Prevent Host Cell Infection
Liu, X, Wang, YL, Wu, J, Qi, J, Zeng, Z, Wan, Q, Chen, Z, Manandhar, P, Cavener, VS, Boyle, NR, Fu, X, Salazar, E, Kuchipudi, SV, Kapur, V, Zhang, X, Umetani, M, Sen, M, Willson, RC, Chen, SH & Zu, Y 2021, , Angewandte Chemie - International Edition, vol. 60, no. 18, pp. 10273-10278. https://doi.org/10.1002/anie.202100345

Oligonucleotide aptamers for pathogen detection and infectious disease control
Wan, Q, Liu, X & Zu, Y 2021, , Theranostics, vol. 11, no. 18, pp. 9133-9161. https://doi.org/10.7150/thno.61804

Genomic complexity is associated with epigenetic regulator mutations and poor prognosis in diffuse large B-cell lymphoma
You, H, Xu-Monette, ZY, Wei, L, Nunns, H, Nagy, ML, Bhagat, G, Fang, X, Zhu, F, Visco, C, Tzankov, A, Dybkaer, K, Chiu, A, Tam, W, Zu, Y, Hsi, ED, Hagemeister, FB, Huh, J, Ponzoni, M, Ferreri, AJM, Møller, MB, Parsons, BM, Van Krieken, JH, Piris, MA, Winter, JN, Li, Y, Au, Q, Xu, B, Albitar, M & Young, KH 2021, , OncoImmunology, vol. 10, no. 1, 1928365. https://doi.org/10.1080/2162402X.2021.1928365