Musser lab Publications


Transmission history of SARS-CoV-2 in humans and white-tailed deer
Willgert, K, Didelot, X, Surendran-Nair, M, Kuchipudi, SV, Ruden, RM, Yon, M, Nissly, RH, Vandegrift, KJ, Nelli, RK, Li, L, Jayarao, BM, Levine, N, Olsen, RJ, Davis, JJ, Musser, JM, Hudson, PJ, Kapur, V & Conlan, AJK 2022, , Scientific Reports, vol. 12, no. 1, 12094. https://doi.org/10.1038/s41598-022-16071-z

Genome-Wide Transposon Mutagenesis Screens Identify Group A Streptococcus Genes Affecting Susceptibility to ß-Lactam Antibiotics
Zhu, L, Eraso, JM, Mangham, RE, Saavedra, MO, Olsen, RJ, Beres, SB & Musser, JM 2022, , Journal of bacteriology, vol. 204, no. 12. https://doi.org/10.1128/jb.00287-22

A Chimeric Penicillin Binding Protein 2X Significantly Decreases in Vitro Beta-Lactam Susceptibility and Increases in Vivo Fitness of Streptococcus pyogenes
Olsen, RJ, Zhu, L, Mangham, RE, Faili, A, Kayal, S, Beres, SB & Musser, JM 2022, , American Journal of Pathology, vol. 192, no. 10, pp. 1397-1406. https://doi.org/10.1016/j.ajpath.2022.06.011

Human M1 macrophages express unique innate immune response genes after mycobacterial infection to defend against tuberculosis
Khan, A, Zhang, K, Singh, VK, Mishra, A, Kachroo, P, Bing, T, Won, JH, Mani, A, Papanna, R, Mann, LK, Ledezma-Campos, E, Aguillon-Duran, G, Canaday, DH, David, SA, Restrepo, BI, Viet, NN, Phan, H, Graviss, EA, Musser, JM, Kaushal, D, Gauduin, MC & Jagannath, C 2022, , Communications Biology, vol. 5, no. 1, 480. https://doi.org/10.1038/s42003-022-03387-9

Signals of Significantly Increased Vaccine Breakthrough, Decreased Hospitalization Rates, and Less Severe Disease in Patients with Coronavirus Disease 2019 Caused by the Omicron Variant of Severe Acute Respiratory Syndrome Coronavirus 2 in Houston, Texas
Christensen, PA, Olsen, RJ, Long, SW, Snehal, R, Davis, JJ, Ojeda Saavedra, M, Reppond, K, Shyer, MN, Cambric, J, Gadd, R, Thakur, RM, Batajoo, A, Mangham, R, Pena, S, Trinh, T, Kinskey, JC, Williams, G, Olson, R, Gollihar, J & Musser, JM 2022, , American Journal of Pathology, vol. 192, no. 4, pp. 642-652. https://doi.org/10.1016/j.ajpath.2022.01.007

Multiple spillovers from humans and onward transmission of SARS-CoV-2 in white-tailed deer
Kuchipudi, SV, Surendran-Nair, M, Ruden, RM, Yon, M, Nissly, RH, Vandegrift, KJ, Nelli, RK, Li, L, Jayarao, BM, Maranas, CD, Levine, N, Willgert, K, Conlan, AJK, Olsen, RJ, Davis, JJ, Musser, JM, Hudson, PJ & Kapur, V 2022, , Proceedings of the National Academy of Sciences of the United States of America, vol. 119, no. 6, e2121644119. https://doi.org/10.1073/pnas.2121644119

Delta Variants of SARS-CoV-2 Cause Significantly Increased Vaccine Breakthrough COVID-19 Cases in Houston, Texas
Christensen, PA, Olsen, RJ, Long, SW, Subedi, S, Davis, JJ, Hodjat, P, Walley, DR, Kinskey, JC, Ojeda Saavedra, M, Pruitt, L, Reppond, K, Shyer, MN, Cambric, J, Gadd, R, Thakur, RM, Batajoo, A, Mangham, R, Pena, S, Trinh, T, Yerramilli, P, Nguyen, M, Olson, R, Snehal, R, Gollihar, J & Musser, JM 2022, , American Journal of Pathology, vol. 192, no. 2, pp. 320-331. https://doi.org/10.1016/j.ajpath.2021.10.019


Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike protein
Javanmardi, K, Segall-Shapiro, TH, Chou, CW, Boutz, DR, Olsen, RJ, Xie, X, Xia, H, Shi, PY, Johnson, CD, Annapareddy, A, Weaver, S, Musser, JM, Ellington, AD, Finkelstein, IJ & Gollihar, JD 2022, , Cell Host and Microbe, vol. 30, no. 9, pp. 1242-1254.e6. https://doi.org/10.1016/j.chom.2022.07.016

Genome-wide transposon mutagenesis screens identify group A streptococcus genes affecting susceptibility to beta-lactam antibiotics
Zhu, L, Eraso, JM, Mangham, R, Ojeda Saavedra, M, Olsen, RJ, Beres, SB & Musser, JM 2022, , Journal of bacteriology.

Systems biology analysis of human genomes points to key pathways conferring spina bifida risk
Aguiar-Pulido, V, Wolujewicz, P, Martinez-Fundichely, A, Elhaik, E, Thareja, G, Aleem, AA, Chalhoub, N, Cuykendall, T, Al-Zamer, J, Lei, Y, El-Bashir, H, Musser, JM, Al-Kaabi, A, Shaw, GM, Khurana, E, Suhre, K, Mason, CE, Elemento, O, Finnell, RH & Elizabeth Ross, M 2021, , Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 51, e2106844118. https://doi.org/10.1073/pnas.2106844118

Analysis of the ARTIC Version 3 and Version 4 SARS-CoV-2 Primers and Their Impact on the Detection of the G142D Amino Acid Substitution in the Spike Protein
Davis, JJ, Wesley Long, S, Christensen, PA, Olsen, RJ, Olson, R, Shukla, M, Subedi, S, Stevens, R & Musser, JM 2021, , Microbiology Spectrum, vol. 9, no. 3, e01803. https://doi.org/10.1128/SPECTRUM.01803-21

Trajectory of Growth of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Variants in Houston, Texas, January through May 2021, Based on 12,476 Genome Sequences
Olsen, RJ, Christensen, PA, Long, SW, Subedi, S, Hodjat, P, Olson, R, Nguyen, M, Davis, JJ, Yerramilli, P, Saavedra, MO, Pruitt, L, Reppond, K, Shyer, MN, Cambric, J, Gadd, R, Thakur, RM, Batajoo, A, Finkelstein, IJ, Gollihar, J & Musser, JM 2021, , American Journal of Pathology, vol. 191, no. 10, pp. 1754-1773. https://doi.org/10.1016/j.ajpath.2021.07.002

Functional insights into the high-molecular-mass penicillin- binding proteins of streptococcus agalactiae revealed by gene deletion and transposon mutagenesis analysis
Zhu, L, Yerramilli, P, Pruitt, L, Mishra, A, Olsen, RJ, Beres, SB, Waller, AS & Musser, JM 2021, , Journal of bacteriology, vol. 203, no. 17, e00234-21. https://doi.org/10.1128/JB.00234-21

The Effect of Convalescent Plasma Therapy on Mortality Among Patients With COVID-19: Systematic Review and Meta-analysis
Klassen, SA, Senefeld, JW, Johnson, PW, Carter, RE, Wiggins, CC, Shoham, S, Grossman, BJ, Henderson, JP, Musser, J, Salazar, E, Hartman, WR, Bouvier, NM, Liu, STH, Pirofski, LA, Baker, SE, van Helmond, N, Wright, RS, Fairweather, DL, Bruno, KA, Wang, Z, Paneth, NS, Casadevall, A & Joyner, MJ 2021, , Mayo Clinic Proceedings, vol. 96, no. 5, pp. 1262-1275. https://doi.org/10.1016/j.mayocp.2021.02.008

Limited window for donation of convalescent plasma with high live-virus neutralizing antibody titers for COVID-19 immunotherapy
Gontu, A, Srinivasan, S, Salazar, E, Nair, MS, Nissly, RH, Greenawalt, D, Bird, IM, Herzog, CM, Ferrari, MJ, Poojary, I, Katani, R, Lindner, SE, Minns, AM, Rossi, R, Christensen, PA, Castillo, B, Chen, J, Eagar, TN, Yi, X, Zhao, P, Leveque, C, Olsen, RJ, Bernard, DW, Gollihar, J, Kuchipudi, SV, Musser, JM & Kapur, V 2021, , Communications Biology, vol. 4, no. 1, 267. https://doi.org/10.1038/s42003-021-01813-y

Significantly Decreased Mortality in a Large Cohort of Coronavirus Disease 2019 (COVID-19) Patients Transfused Early with Convalescent Plasma Containing High-Titer Anti–Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Protein IgG
Salazar, E, Christensen, PA, Graviss, EA, Nguyen, DT, Castillo, B, Chen, J, Lopez, BV, Eagar, TN, Yi, X, Zhao, P, Rogers, J, Shehabeldin, A, Joseph, D, Masud, F, Leveque, C, Olsen, RJ, Bernard, DW, Gollihar, J & Musser, JM 2021, , American Journal of Pathology, vol. 191, no. 1, pp. 90-107. https://doi.org/10.1016/j.ajpath.2020.10.008

Sequence Analysis of 20,453 Severe Acute Respiratory Syndrome Coronavirus 2 Genomes from the Houston Metropolitan Area Identifies the Emergence and Widespread Distribution of Multiple Isolates of All Major Variants of Concern
Long, SW, Olsen, RJ, Christensen, PA, Subedi, S, Olson, R, Davis, JJ, Saavedra, MO, Yerramilli, P, Pruitt, L, Reppond, K, Shyer, MN, Cambric, J, Finkelstein, IJ, Gollihar, J & Musser, JM 2021, , American Journal of Pathology, vol. 191, no. 6, pp. 983-992. https://doi.org/10.1016/j.ajpath.2021.03.004

Real-world Assessment of 2879 COVID-19 Patients Treated With Monoclonal Antibody Therapy: A Propensity Score–Matched Cohort Study
Cooper, MH, Christensen, PA, Salazar, E, Perez, KK, Graviss, EA, Nguyen, D, Musser, JM, Huang, HJ & Liebl, MG 2021, , Open Forum Infectious Diseases, vol. 8, no. 11, ofab512. https://doi.org/10.1093/ofid/ofab512

Genetic basis underlying the hyperhemolytic phenotype of streptococcus agalactiae strain CNCTC10/84
Zhu, L, Beres, SB, Yerramilli, P, Pruitt, L, Cantu, CC, Olsen, RJ & Musser, JM 2020, , Journal of bacteriology, vol. 202, no. 23, e00504-20. https://doi.org/10.1128/JB.00504-20