Olsen lab Publications


Genomic Landscape of Intrahost Variation in Group A Streptococcus: Repeated and Abundant Mutational Inactivation of the fabT Gene Encoding a Regulator of Fatty Acid Synthesis
Eraso, JM, Olsen, RJ, Beres, SB, Kachroo, P, Porter, AR, Nasser, W, Bernard, PE, DeLeo, FR & Musser, JM 2016, Infection and Immunity, vol 84, no. 12, pp. 3268-3281. DOI:

A prospective observational cohort study in primary care practices to identify factors associated with treatment failure in Staphylococcus aureus skin and soft tissue infections
Lee, GC, Hall, RG, Boyd, NK, Dallas, SD, Du, LC, Treviño, LB, Treviño, SB, Retzloff, C, Lawson, KA, Wilson, J, Olsen, RJ, Wang, Y & Frei, CR 2016, Annals of Clinical Microbiology and Antimicrobials, vol 15, no. 1, 58. DOI:

Predictors of community-associated Staphylococcus aureus, methicillin-resistant and methicillin-susceptible Staphylococcus aureus skin and soft tissue infections in primary-care settings
LEE, GC, HALL Hall, RG, BOYD, NK, DALLAS, SD, DU, LC, TREVIÑO, LB, RETZLOFF, C, TREVIÑO, SB, LAWSON, KA, WILSON, JP, OLSEN, RJ, WANG, Y & FREI, CR 2016, Epidemiology and Infection, pp. 1-7. DOI:

Increased use of surgical energy promotes methicillin-resistant Staphylococcus aureus colonization in rabbits following open ventral hernia mesh repair
Fernandez-Moure, JS, van Eps, JL, Peress, L, Cantu, C, Olsen, RJ, Jenkins, L, Cabrera, FJ, Tasciotti, E, Weiner, BK & Dunkin, BJ 2016, Surgical Endoscopy and Other Interventional Techniques, pp. 1-9. DOI:

Next-generation sequencing of matched primary and metastatic rectal adenocarcinomas demonstrates minimal mutation gain and concordance to colonic adenocarcinomas
Crumley, SM, Pepper, KL, Phan, AT, Olsen, RJ, Schwartz, MR & Portier, BP 2016, Archives of Pathology and Laboratory Medicine, vol 140, no. 6, pp. 529-535. DOI:

Intergenic variable-number tandem-repeat polymorphism upstream of rocA alters toxin production and enhances virulence in Streptococcus pyogenes
Zhu, L, Olsen, RJ, Horstmann, N, Shelburne, SA, Fan, J, Hu, T & Musser, JM 2016, Infection and Immunity, vol 84, no. 7, pp. 2086-2093. DOI:

Integrating rapid diagnostics and antimicrobial stewardship in two community hospitals improved process measures and antibiotic adjustment time
Lockwood, AM, Perez, KK, Musick, WL, Ikwuagwu, JO, Attia, E, Fasoranti, OO, Cernoch, PL, Olsen, RJ & Musser, JM 2016, Infection Control and Hospital Epidemiology, vol 37, no. 4, pp. 425-432. DOI:

Structural and functional analysis of RopB: A major virulence regulator in Streptococcus pyogenes
Makthal, N, Gavagan, M, Do, H, Olsen, RJ, Musser, JM & Kumaraswami, M 2016, Molecular Microbiology, vol 99, no. 6, pp. 1119-1133. DOI:

Intergenic variable-number tandem-repeat polymorphism upstream of rocA alters toxin production and enhances virulence in Streptococcus pyogenes
Zhu, L, Olsen, RJ, Horstmann, N, Shelburne, SA, Fan, J, Hu, Y & Musser, JM 2016, Infection and Immunity, vol 84, no. 7, pp. 2086-2093.

Transcriptome remodeling contributes to epidemic disease caused by the human pathogen Streptococcus pyogenes
Beres, SB, Kachroo, P, Nasser, W, Olsen, RJ, Zhu, L, Flores, AR, de la Riva, I, Paez-Mayorga, J, Jimenez, FE, Cantu, C, Vuopio, J, Jalava, J, Kristinsson, KG, Gottfredsson, M, Corander, J, Fittipaldi, N, Di Luca, MC, Petrelli, D, Vitali, LA, Raiford, A, Jenkins, L & Musser, JM 2016, mBio, vol 7, no. 3, e00403-16. DOI:


Adhesin competence repressor (AdcR) from Streptococcus pyogenes controls adaptive responses to zinc limitation and contributes to virulence
Sanson, M, Makthal, N, Flores, AR, Olsen, RJ, Musser, JM & Kumaraswami, M 2015, Nucleic Acids Research, vol 43, no. 1, pp. 418-432. DOI:

A molecular trigger for intercontinental epidemics of group A Streptococcus
Zhu, L, Olsen, RJ, Nasser, W, Beres, SB, Vuopio, J, Kristinsson, KG, Gottfredsson, M, Porter, AR, DeLeo, FR & Musser, JM 2015, The Journal of clinical investigation, vol 125, no. 9, pp. 3545-3559. DOI:

A new ever-evolving paradigm
Cagle, PT , Olsen, RJ, Portier, BP, Takei, H & Bernard, DW 2015, Archives of Pathology and Laboratory Medicine, vol 139, no. 4, pp. 446-447. DOI:

Comparative whole genome sequencing of community-associated methicillin-resistant Staphylococcus aureus sequence type 8 from primary care clinics in a Texas community
Lee, GC, Long, SW, Musser, JM, Beres, SB, Olsen, RJ, Dallas, SD, Nunez, YO & Frei, CR 2015, Pharmacotherapy, vol 35, no. 2, pp. 220-228. DOI:

Improving positive blood culture removal time significantly decreases total processing time
Salazar, E, Divatia, M, Cernoch, PL, Olsen, RJ, Long, SW, Land, GA, Davis, JR & Musser, JM 2015, Archives of Pathology and Laboratory Medicine, vol 139, no. 2, pp. 199-203. DOI:

Trading capsule for increased cytotoxin production: Contribution to virulence of a newly emerged clade of emm89 streptococcus pyogenes
Zhu, L, Olsen, RJ, Nasser, W, De La Riva Morales, I & Mussera, JM 2015, mBio, vol 6, no. 5, e01378-15.

The majority of 9,729 group A streptococcus strains causing disease secrete SpeB cysteine protease: Pathogenesis implications
Olsen, RJ, Raghuram, A, Cantu, C, Hartman, MH, Jimenez, FE, Lee, S, Ngo, A, Rice, KA, Saddington, D, Spillman, H, Valson, C, Flores, AR, Beres, SB, Wesley Long, S, Nasser, W & Musser, JM 2015, Infection and Immunity, vol 83, no. 12, pp. 4750-4758. DOI:

A single amino acid replacement in the sensor kinase lias contributes to a carrier phenotype in group a streptococcus
Flores, AR, Jewell, BE, Yelamanchili, D, Olsen, RJ & Musser, JM 2015, Infection and Immunity, vol 83, no. 11, pp. 4237-4246. DOI:

Precision Medicine Resource Guide
Olsen, R 2015, . College of American Pathologists.