Associate Professor of Nanomedicine, Academic Institute
Associate Member, Research Institute
Houston Methodist
Dr. Xuewu Liu got his Ph.D. in 2002, then undertook a postdoctoral training at the Indiana Center for Biological Microscopy at IUPUI Indianapolis. In 2003, he joined Ohio State University as a senior research associate in nanomedicine. He was appointed assistant professor of nanomedicine and biomedical engineering at the University of Texas Health Science Center in Houston in 2006. In 2010, Dr. Liu joined to The Methodist Hospital Research Institute, to direct the nanoengineering core.
Dr. Xuewu Liu is a leading scientist in silicon nanotechnology. With over 20 years of experience in silicon microfabrication, nanomaterials, microfluidics, and cancer nanotechnology, Dr. Liu has been leading the effort in the research and development of silicon-based nanomedicine platforms, and coordinates a nanoengineering team to support biomedical research at the institute levels. The nanomedicine platforms he developed include porous silicon nanovectors for drug delivery, multifunctional nanoparticles, nanochannel membranes for drug implants, nanostructure enhanced microfluidic devices, injectable nanoparticulate scavengers, and nanoporous assay for diagnostic biomarkers. Dr. Liu had published 150 peer-reviewed journal papers, and issued 10 US patents. He is intensively involved in the researches on targeted cancer therapy, in vitro and in vivo studies of particles-cells interaction, implanted drug delivery, microfluidic analysis of exosomes, and particulate cytokine scavengers for immune regulation. As the director of nanoengineering, he led the cleanroom microfabrication and the development of in-house nanofabrication capabilities in the Houston Methodist cGMP facility. His current active researches focus on microfluidic study of platelet-mediated tumor metastasis, injectable cytokine scavenging for immune modulation, and microfluidic cell manipulation for the study of intracellular interaction at single cell level.
Dr. Liu’s research focus is the development of silicon based nanotechnology platforms for prevention, diagnosis and treatment of human disease. His current interests include microfluidic study of platelet-mediated tumor metastasis, injectable cytokine scavenging for immune modulation, and microfluidic cell manipulation for the study of intracellular interaction at single cell level.