William R. Miller, MD

Assistant Professor of Medicine, Academic Institute
Assistant Clinical Member, Research Institute
Houston Methodist


Publications

Bacterial cell membranes and their role in daptomycin resistance: A review
Nguyen, AH, Hood, K, Mileykovskaya, E, Miller, WR & Tran, C 2022, , Frontiers in Molecular Biosciences. https://doi.org/10.3389/fmolb.2022.1035574

LiaF is required for LiaX mediated protection against daptomycin and LL-37 in Enterococcus faecalis OG1RF
Panesso, D, Singh, KV, Villegas, SG, Khan, A, Supandy, A, Nguyen, AH, Rincon, S, Wood, K, Dinh, A, Research, H, Miller, WR, Shamoo, Y, Tran, C & Arias, CA 2022, . in LiaF is required for LiaX mediated protection against daptomycin and LL-37 in Enterococcus faecalis OG1RF. <https://www.eventscribe.net/2022/IDWeek/searchGlobal.asp>

Unravelling complex transposable elements surrounding blaGES-16 in a Pseudomonas aeruginosa ExoU strain
Streling, AP, Cayô, R, Catan, TA, Jové, T, Santos, FF, Nodari, CS, Hanson, B, Miller, WR, Shropshire, W, Dinh, AQ, Ribeiro, J, Pignatari, ACC, Arias, CA & Gales, AC 2022, , Journal of Global Antimicrobial Resistance, vol. 30, pp. 143-147. https://doi.org/10.1016/j.jgar.2022.04.009

Antimicrobial Susceptibility Testing for Enterococci
Khan, A, Miller, WR, Axell-House, D, Munita, JM & Arias, CA 2022, , Journal of Clinical Microbiology, vol. 60, no. 9. https://doi.org/10.1128/jcm.00843-21

Prevalence and Characterization of the Cefazolin Inoculum Effect in North American Methicillin-Susceptible Staphylococcus aureus Isolates
CLSI Cefazolin High Inoculum Ad-Hoc Working Group 2022, , Journal of Clinical Microbiology, vol. 60, no. 7. https://doi.org/10.1128/jcm.02495-21

Evolution of Enterococcus faecium in Response to a Combination of Daptomycin and Fosfomycin Reveals Distinct and Diverse Adaptive Strategies
Supandy, A, Mehta, HH, Tran, TT, Miller, WR, Zhang, R, Xu, L, Arias, CA & Shamoo, Y 2022, , Antimicrobial Agents and Chemotherapy, vol. 66, no. 6. https://doi.org/10.1128/aac.02333-21

Real-World Performance of Susceptibility Testing for Ceftolozane/Tazobactam against Non-Carbapenemase- Producing Carbapenem-Resistant Pseudomonas aeruginosa
Rivas, L, Alcalde-Rico, M, Martínez, JRW, Moreno, MV, Rojas, P, Wozniak, A, García, P, Olivares-Pacheco, J, Miller, WR, Arias, CA, Khan, A & Munita, JM 2022, , Antimicrobial Agents and Chemotherapy, vol. 66, no. 1, e01657-21. https://doi.org/10.1128/AAC.01657-21

Association of PBP4 Variants and ß-lactam Susceptibility in Enterococcus faecalis
Tran, C, Simar, SR, Egge, S, Atterstrom, R, Dinh, AQ, Hanson, BM, Contreras, GA, Zervos, MJ, Abbo, LM, Shimose, LA, Shelburne, SA, Arias, CA & Miller, WR 2022, , IDWeek 2022, 10/19/22 - 10/23/22.

Evolution of Cefiderocol Non-Susceptibility in Pseudomonas aeruginosa in a Patient Without Previous Exposure to the Antibiotic
Streling, AP, Al Obaidi, MM, Lainhart, WD, Zangeneh, T, Khan, A, Dinh, AQ, Hanson, B, Arias, CA & Miller, WR 2021, , Clinical Infectious Diseases, vol. 73, no. 11, pp. E4472-E4474. https://doi.org/10.1093/cid/ciaa1909

Activation of the Enterococcus faecalis Cell Envelope Stress Response through the Novel MadRS System Is Associated With Increased Size of Cardiac Microlesions
Miller, WR, Singh, KV & Arias, CA 2021, . in Activation of the Enterococcus faecalis Cell Envelope Stress Response through the Novel MadRS System Is Associated With Increased Size of Cardiac Microlesions. vol. 8, PMCID: PMC8644875, Open Forum Infect Dis. USA. https://doi.org/10.1093/ofid/ofab466.1196

Polymorphisms in Key Regulatory Regions of the bla operon Correlate with the Cefazolin Inoculum Effect in Methicillin-Susceptible Staphylococcus aureus (MSSA)
Gomez-Villegas, SI, Rios, R, Diaz, L, Dinh, A, Panesso, D, Rincon, S, Carvajal, LP, Reyes, MI, Murray, BE, Miller, WR, Singh, KV, Reyes, J & Arias, CA 2021, . https://doi.org/doi: 10.1093/ofid/ofab466.199

Evaluation of susceptibility testing methods for aztreonam and ceftazidime-avibactam combination therapy on extensively drug-resistant gram-negative organisms
Khan, A, Erickson, SG, Pettaway, C, Arias, CA, Miller, WR & Bhatti, MM 2021, , Antimicrobial Agents and Chemotherapy, vol. 65, no. 11, e00846-21. https://doi.org/10.1128/AAC.00846-21

Genomic analysis of carbapenem-resistant Pseudomonas aeruginosa ST143 clone showing susceptibility to broad-spectrum cephalosporins
Streling, AP, Cayô, R, Nodari, CS, Almeida, LGP, Santos, FF, Hanson, B, Dinh, AQ, Vasconcelos, ATR, Miller, WR, Arias, CA & Gales, AC 2021, , Journal of Global Antimicrobial Resistance, vol. 26, pp. 177-179. https://doi.org/10.1016/j.jgar.2021.05.019

Erratum: A multicenter study to evaluate ceftaroline breakpoints: Performance in an area with high prevalence of methicillin-resistant Staphylococcus aureus sequence type 5 lineage (J Clin Microbiol (2019) 57:9 (e00798-19) DOI: 10.1128/JCM.00798-19)
Khan, A, Rivas, LM, Spencer, M, Martinez, R, Lam, M, Rojas, P, Porte, L, Silva, F, Braun, S, Valdivieso, F, M?lhauser, M, Lafourcade, M, Miller, WR, García, P, Arias, CA & Munita, JM 2021, , Journal of Clinical Microbiology, vol. 59, no. 6, e00734-21. https://doi.org/10.1128/JCM.00734-21

A Test for the Rapid Detection of the Cefazolin Inoculum Effect in Methicillin-Susceptible Staphylococcus aureus
Rincon, S, Carvajal, LP, Gomez-Villegas, SI, Echeverri, AM, Rios, R, Dinh, A, Pedroza, C, Ordoñez, KM, Nannini, E, Sun, Z, Fowler, VG, Murray, BE, Miller, WR, Palzkill, T, Diaz, L, Arias, CA & Reyes, J 2021, , Journal of Clinical Microbiology, vol. 59, no. 4, e01938-20. https://doi.org/10.1128/JCM.01938-20

Daptomycin resistance in enterococcus faecium can be delayed by disruption of the LiaFSR stress response pathway
Prater, AG, Mehta, HH, Beabout, K, Supandy, A, Miller, WR, Tran, TT, Arias, CA & Shamoo, Y 2021, , Antimicrobial Agents and Chemotherapy, vol. 65, no. 4, e01317-20. https://doi.org/10.1128/AAC.01317-20

Resistance in Vancomycin-Resistant Enterococci
Miller, WR, Murray, BE, Rice, LB & Arias, CA 2020, , Infectious Disease Clinics of North America, vol. 34, no. 4, pp. 751-771. https://doi.org/10.1016/j.idc.2020.08.004

Whole-genome sequencing of Staphylococcus epidermidis bloodstream isolates from a prospective clinical trial reveals that complicated bacteraemia is caused by a limited number of closely related sequence types
Shelburne, S, Dib, RW, Endres, BT, Reitzel, R, Li, X, Kalia, A, Sahasrabhojane, P, Chaftari, AM, Hachem, R, Vargas-Cruz, NS, Jiang, Y, Garey, K, Fowler, VG, Holland, TL, Gu, J, Miller, W, Sakurai, A, Arias, CA, Aitken, SL, Greenberg, DE, Kim, J, Flores, AR & Raad, I 2020, , Clinical Microbiology and Infection, vol. 26, no. 5, pp. 646.e1-646.e8. https://doi.org/10.1016/j.cmi.2019.10.008

Consider the ‘Hole’ Differential: Pulmonary Malignancy Presenting as a Cavitary Lesion
Kohnke, LQ, Hostetter, LJ, Subramanian, SK & Miller, WR 2020, , American Journal of Medicine, vol. 133, no. 4, pp. 438-440. https://doi.org/10.1016/j.amjmed.2019.08.045

Simultaneous infection with enterobacteriaceae and pseudomonas aeruginosa harboring multiple carbapenemases in a returning traveler colonized with candida auris
Khan, A, Shropshire, WC, Hanson, B, Dinh, AQ, Wanger, A, Ostrosky-Zeichner, L, Arias, CA & Miller, WR 2020, , Antimicrobial Agents and Chemotherapy, vol. 64, no. 2, e01466. https://doi.org/10.1128/AAC.01466-19