Suzanne Zein-Eldin Powell, MD

Professor of Pathology and Genomic Medicine, Academic Institute
Program Director, Anatomic & Clinical Residency and Neuropathology Fellowship, Department of Pathology & Genomic Medicine
Houston Methodist
Weill Cornell Medical College


Anatomic and Clinical Pathology Residency


Biography

In addition to serving as Professor of Pathology & Genomic Medicine with Weill Medical College of Cornell University and Texas A & M University, Dr. Suzanne Powell directs the Pathology residency program at Houston Methodist Hospital. Her previous teaching experience has included ranks as assistant professorship at the University of Florida and Baylor College of Medicine, where she received the Outstanding Resident Teaching Award in Anatomic Pathology. Active in pathology research, Dr. Powell is the Co-Director (with Greg N. Fuller, MD, PhD, at MD Anderson) of the Houston Methodist/MD Anderson Neuropathology Fellowship Program which also includes activities at Texas Children's Hospital, Ben Taub General Hospital, and Baylor College of Medicine. Dr. J. Clay Goodman serves as the site Director for the BCM activities of the fellowship program. She has served as Chair of PRODS Council and the Residency Review Committee for Pathology of the ACGME, as a member of the working groups for the development of Milestones for Pathology and most recently for Milestones in Neuropathology. She was recently appointed as member of the Neuropathology Test Development Committee of the American Board of Pathology and is a member of the United States and Canadian Academy (USCAP) Board of Directors.

Description of Research

Dr. Powell's area of expertise is neuropathology. Her research interests are clinically based, and focus on dementia and neurodegenerative disease. She serves as the diagnostic neuropathologist for the Baylor College of Medicine Alzheimer´s Disease Center.

Areas Of Expertise

Brain tumors Dementia Alzheimer's Disease
Education & Training

Clinical Fellowship, University of Florida
Residency, University of Florida
MD, West Virginia University School of Medicine
Publications

Anterior insula is more vulnerable than posterior insula to TDP-43 pathology in common dementias and ALS
Lochner, RH, Arumanayagam, AS, Powell, SZ, Masdeu, JC, Pascual, B & Cykowski, MD 2024, , Journal of Neuropathology and Experimental Neurology, vol. 83, no. 5, pp. 307-317. https://doi.org/10.1093/jnen/nlae027

National pilot of entrustable professional activities in pathology residency training
Bryant, BH, Anderson, SR, Brissette, M, Childs, JM, Gratzinger, D, Johnson, K, Powell, DE, Zein-Eldin Powell, S, Timmons, CF, Chute, D, Cummings, TJ, Furlong, MA, Hébert, TM, Reeves, HM, Rush, D, Vitkovski, T & McCloskey, CB 2024, , Academic Pathology, vol. 11, no. 2, 100110, pp. 100110. https://doi.org/10.1016/j.acpath.2024.100110

Leveraging faculty development to support validation of entrustable professional activities assessment tools in anatomic and clinical pathology training
Bryant, BH, Anderson, SR, Brissette, M, Childs, JM, Gratzinger, D, Johnson, K, Powell, DE, Zein-Eldin Powell, S, Timmons, CF & McCloskey, CB 2024, , Academic Pathology, vol. 11, no. 2, 100111. https://doi.org/10.1016/j.acpath.2024.100111

Analysis of gliomas DNA methylation: Assessment of pre-analytical variables
Bomsztyk, K, Mar, D, Denisenko, O, Powell, S, Vishnoi, M, Delegard, J, Patel, A, Ellenbogen, RG, Ramakrishna, R & Rostomily, R 2024, , bioRxiv. https://doi.org/10.1101/2024.03.26.586350

Angiomatoid fibrous histiocytoma: primary intracranial lesion with thoracic spine metastasis and a malignant course. Illustrative case
Demand, A, Barber, S, Powell, S & Britz, G 2024, , Journal of Neurosurgery: Case Lessons, vol. 7, no. 1, CASE23535. https://doi.org/10.3171/CASE23535

Molecular profiling identifies at least 3 distinct types of posttransplant lymphoproliferative disorder involving the CNS
Guney, E, Lucas, CHG, Singh, K, Pekmezci, M, Fernandez-Pol, S, Mirchia, K, Toland, A, Vogel, H, Bannykh, S, Schafernak, KT, Alexandrescu, S, Mobley, BC, Powell, S, Davidson, CJ, Neltner, J, Boué, DR, Hattab, E, Ferris, SP, Ohgami, RS, Rubenstein, JL, Bollen, AW, Tihan, T, Perry, A, Solomon, DA & Wen, KW 2023, , Blood Advances, vol. 7, no. 13, pp. 3307-3311. https://doi.org/10.1182/bloodadvances.2022009521

Primary visual cortex pathology in ALS patients with C9ORF72 expansion
Cykowski, MD, Arumanayagam, AS, Powell, SZ & Appel, SH 2024, , Brain Pathology, vol. 34, no. 5, e13229. https://doi.org/10.1111/bpa.13229

Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target
Abdelfattah, N, Kumar, P, Wang, C, Leu, JS, Flynn, WF, Gao, R, Baskin, DS, Pichumani, K, Ijare, OB, Wood, SL, Powell, SZ, Haviland, DL, Parker Kerrigan, BC, Lang, FF, Prabhu, SS, Huntoon, KM, Jiang, W, Kim, BYS, George, J & Yun, K 2022, , Nature Communications, vol. 13, no. 1, 767, pp. 767. https://doi.org/10.1038/s41467-022-28372-y, https://doi.org/10.1038/s41467-022-28372-y

Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target
Abdelfattah, N, Kumar, P, Wang, C, Leu, JS, Flynn, WF, Gao, R, Baskin, DS, Pichumani, K, Ijare, OB, Wood, SL, Powell, SZ, Haviland, DL, Parker Kerrigan, BC, Lang, FF, Prabhu, SS, Huntoon, KM, Jiang, W, Kim, BYS, George, J & Yun, K 2022, , Nature Communications, vol. 13, no. 1, 767. https://doi.org/10.1038/s41467-022-28372-y

Patterns of amygdala region pathology in LATE-NC: subtypes that differ with regard to TDP-43 histopathology, genetic risk factors, and comorbid pathologies
Cykowski, MD, Arumanayagam, AS, Powell, SZ, Rivera, AL, Abner, EL, Roman, GC, Masdeu, JC & Nelson, PT 2022, , Acta Neuropathologica, vol. 143, no. 5, pp. 531-545. https://doi.org/10.1007/s00401-022-02416-5

Metastatic urothelial carcinoma to the brain, spinal cord and spine: A contemporary multi-institutional clinicopathologic analysis of 24 cases
Ogunbona, OB, Matoso, A, Cheng, L, Shen, S, Powell, SZ & Osunkoya, AO 2021, , Pathology Research and Practice, vol. 224, 153537. https://doi.org/10.1016/j.prp.2021.153537

Fast progression in amyotrophic lateral sclerosis is associated with greater tdp-43 burden in spinal cord
Cathcart, SJ, Appel, SH, Peterson, LE, Greene, EP, Powell, SZ, Arumanayagam, AS, Rivera, AL & Cykowski, MD 2021, , Journal of Neuropathology and Experimental Neurology, vol. 80, no. 8, pp. 754-763. https://doi.org/10.1093/jnen/nlab061

Solitary Leptomeningeal Recurrence From Prostate Adenocarcinoma After Treatment With Cytotoxic Gene Therapy, Radiation Therapy, and Androgen Deprivation Therapy
Chevli, N, Curtis, AE, Powell, S, New, P, Butler, EB & Teh, BS 2021, , Advances in Radiation Oncology, vol. 6, no. 4, 100711. https://doi.org/10.1016/j.adro.2021.100711

Evidence-Based Alignment of Pathology Residency With Practice II: Findings and Implications
Black-Schaffer, WS, Robboy, SJ, Gross, DJ, Crawford, JM, Johnson, K, Austin, M, Karcher, DS, Johnson, RL, Powell, SZ, Sanfrancesco, J & Cohen, MB 2021, , Academic Pathology, vol. 8, pp. 23742895211002816. https://doi.org/10.1177/23742895211002816

Spinal cord and motor neuron TDP-43 pathology in a sporadic inclusion body myositis patient
Cathcart, SJ, Greene, EP, Powell, SZ, Arumanayagam, AS, Rivera, AL, Tawil, R, Appel, SH & Cykowski, MD 2021, , Journal of Neuropathology and Experimental Neurology, vol. 79, no. 10, pp. 1130-1133. https://doi.org/10.1093/JNEN/NLAA066

Pathology Trainee Redeployment and Education During the COVID-19 Pandemic: An Institutional Experience
Monroig-Bosque, PDC, Hsu, JW, Lin, MS, Shehabeldin, AN, Rogers, JT, Kim, CF, Kalsekar, AG, Jin, Z, Cara, LR, Barbieri, AN, El-Zaatari, Z, Eskandari, G, Sheu, TG, Tomsula, JA, Long, SW, Zieske, AW, Leveque, CM, Salazar, E, Mody, DR, Schwartz, MR, Cykowski, MD, Yi, X, Powell, SZ & Thomas, JS 2020, , Academic Pathology, vol. 7. https://doi.org/10.1177/2374289520953548

A 70-Year Old Man with Dystonic and Choreiform Movements
Perez, A, Roman, GC, Powell, SZ-E, Fisher, R, Rivera, AL, Masdeu, JC & Cykowski, MD 2020, , Brain Pathology, vol. 30, no. 2, pp. 415-416. https://doi.org/10.1111/bpa.12819

Entry of Graduates of US Pathology Residency Programs Into the Workforce: Cohort Data Between 2008 and 2016 Remain Positive and Stable
Timmons, CF, Black-Schaffer, WS, Naritoku, WY, Powell, SZ, Johnson, KA, Brissette, MD, Childs, JM, Conran, RM, Dixon, LR, George, MR, Gratzinger, D, McCloskey, CB, Prieto, VG, Roberts, CA, Rojiani, AM, Shyu, I & Hoffman, RD 2020, , Academic Pathology, vol. 7. https://doi.org/10.1177/2374289520901833

OCIAD1 contributes to neurodegeneration in Alzheimer’s disease by inducing mitochondria dysfunction, neuronal vulnerability and synaptic damages
Li, X, Wang, L, Cykowski, MD, He, T, Liu, T, Chakranarayan, J, Rivera, A, Zhao, H, Powell, SZ-E, Xia, W & Wong, ST 2020, , EBioMedicine, vol. 51, 102569. https://doi.org/10.1016/j.ebiom.2019.11.030

Dipeptide repeat (DPR) pathology in the skeletal muscle of ALS patients with C9ORF72 repeat expansion
Cykowski, MD, Dickson, DW, Powell, SZ, Arumanayagam, AS, Rivera, AL & Appel, SH 2019, , Acta Neuropathologica, vol. 138, no. 4, pp. 667-670. https://doi.org/10.1007/s00401-019-02050-8