Sherif Nagueh, MD

Professor of Cardiology, Academic Institute
Full Member, Research Institute
Houston Methodist
Weill Cornell Medical College


In 1996, Dr. Nagueh joined the Section of Cardiology in the Department of Medicine at the Baylor College of Medicine as an Assistant Professor. He was promoted in 2001 to an Associate Professor, and became the T.L.L Temple/William H. Spencer, MD Chair in Clinical Cardiology there in 2004. Dr. Nagueh assumed his positions at Houston Methodist in 2005.

Description of Research

Dr. Nagueh´s research career has been in the field of echocardiography. He has authored or co-authored over 100 manuscripts in peer reviewed journals and four book chapters. His research interest has been in the evaluation of diastolic function with tissue Doppler and its application in hypertrophic cardiomyopathy, particularly in patients undergoing alcohol septal ablation.

Areas Of Expertise

Alcohol septal ablation Echocardiography Diastolic function Doppler
Education & Training

Residency, Baylor College of Medicine
Clinical Fellowship
MD, University of Cairo
Active Clinical Trials

HCMR - Novel



Left atrial dysfunction in sickle cell anemia is associated with diffuse myocardial fibrosis, increased right ventricular pressure and reduced exercise capacity
Alsaied, T, Niss, O, Tretter, JT, Powell, AW, Chin, C, Fleck, RJ, Cnota, JF, Malik, P, Quinn, CT, Nagueh, S, Taylor, MD & Mazur, WM 2020, Scientific reports, vol. 10, no. 1, 1767.

Multimodality Imaging in Hypertrophic Cardiomyopathy for Risk Stratification
Tower-Rader, A, Kramer, CM, Neubauer, S, Nagueh, S & Desai, MY 2020, Circulation. Cardiovascular imaging, vol. 13, no. 2, pp. e009026.

Case-Based Imaging Curriculum
Nagueh, S & Chandrashekhar, Y 2020, JACC: Cardiovascular Imaging, vol. 13, no. 1, pp. 343-344.

The 2016 Diastolic Function Guideline: Is it Already Time to Revisit or Revise Them?
Oh, JK, Miranda, WR, Bird, JG, Kane, GC & Nagueh, S 2020, JACC: Cardiovascular Imaging, vol. 13, no. 1, pp. 327-335.

Noninvasive Imaging for the Evaluation of Diastolic Function: Promises Fulfilled
Nagueh, S & Chandrashekhar, Y 2020, JACC: Cardiovascular Imaging, vol. 13, no. 1, pp. 339-342.

Prognostic Implications of Diffuse Interstitial Fibrosis in Asymptomatic Primary Mitral Regurgitation
Kitkungvan, D, Yang, EY, El Tallawi, KC, Nagueh, S, Nabi, F, Khan, MA, Nguyen, DT, Graviss, EA, Lawrie, GM, Zoghbi, WA, Bonow, RO, Quiñones, MA & Shah, DJ 2019, Circulation, vol. 140, no. 25, pp. 2122-2124.

Myocardial Extracellular Volume Fraction Adds Prognostic Information Beyond Myocardial Replacement Fibrosis
Yang, EY, Ghosn, MG, Khan, MA, Gramze, NL, Brunner, G, Nabi, F, Nambi, V, Nagueh, SF, Nguyen, DT, Graviss, EA, Schelbert, EB, Ballantyne, CM, Zoghbi, WA & Shah, DJ 2019, Circulation. Cardiovascular imaging, vol. 12, no. 12, pp. e009535.

Interobserver Variability in Applying American Society of Echocardiography/European Association of Cardiovascular Imaging 2016 Guidelines for Estimation of Left Ventricular Filling Pressure
for Diastolic Function Assessment Collaborators 2019, Circulation. Cardiovascular imaging, vol. 12, no. 1, pp. e008122.

Multivariable models for the diagnosis of pulmonary hypertension
Nagueh, S 2019, Journal of cardiovascular medicine (Hagerstown, Md.), vol. 20, no. 12, pp. 816-817.

Vein of Marshall ethanol infusion for persistent atrial fibrillation: VENUS and MARS clinical trial design
Valderrábano, M, Peterson, LE, Bunge, R, Prystash, M, Dave, A, Nagueh, S & Kleiman, N 2019, American Heart Journal, vol. 215, pp. 52-61.

The Author's Reply:
Nagueh, S 2019, JACC: Cardiovascular Imaging, vol. 12, no. 8P1.

Association of left atrial volume index and all-cause mortality in patients referred for routine cardiovascular magnetic resonance: a multicenter study
Khan, MA, Yang, EY, Zhan, Y, Judd, RM, Chan, W, Nabi, F, Heitner, JF, Kim, RJ, Klem, I, Nagueh, S & Shah, DJ 2019, Journal of Cardiovascular Magnetic Resonance, vol. 21, no. 1, 4, pp. 4.

Left Ventricular Diastolic Function: Understanding Pathophysiology, Diagnosis, and Prognosis With Echocardiography
Nagueh, S 2019, JACC: Cardiovascular Imaging.

Left atrial function: an overlooked metrics in clinical routine echocardiography
Badano, LP, Nagueh, S & Muraru, D 2019, European Journal of Heart Failure.

Understanding by General Providers of the Echocardiogram Report
Trang, A, Kampangkaew, J, Fernandes, R, Tiwana, J, Misra, A, Hamzeh, I, Blaustein, A, Aguilar, D, Shah, T, Ballantyne, C, Quiñones, MA, Nagueh, S, Dokanish, H, Virani, SS, Deswal, A, Kirkpatrick, JN & Nambi, V 2019, American Journal of Cardiology.

Impact of High Baseline Left Ventricular Filling Pressure on Transcatheter Aortic Valve Replacement Outcomes in Patients with Significant Mitral Annular Calcification
Truong, VT, Mazur, W, Palmer, C, Egnaczyk, GF, Kereiakes, DJ, Sarembock, IJ, Choo, JK, Shreenivas, S, Nagueh, S & Chung, ES 2019, Journal of the American Society of Echocardiography.

Demonstrating the Value of Outcomes in Echocardiography: Imaging-Based Registries in Improving Patient Care
Strom, JB, Tanguturi, VK, Nagueh, S, Klein, AL & Manning, WJ 2019, Journal of the American Society of Echocardiography.

Normal Ranges of Left Ventricular Strain by Three-Dimensional Speckle-Tracking Echocardiography in Adults: A Systematic Review and Meta-Analysis
Truong, VT, Phan, HT, Pham, KNP, Duong, HNH, Ngo, TNM, Palmer, C, Nguyen, TTH, Truong, BH, Vo, MA, Tretter, JT, Nagueh, S, Chung, ES & Mazur, W 2019, Journal of the American Society of Echocardiography.

Imaging for Risk Stratification of Sudden Cardiac Death in Patients With Arrhythmogenic Cardiomyopathy *
Nagueh, SF 2018, JACC: Cardiovascular Imaging, vol. 11, no. 10, pp. 1387-1389.

Cardiac Resynchronization Therapy and Dynamic Changes in Right Ventricular Function
Nagueh, S 2018, Circulation. Cardiovascular imaging, vol. 11, no. 9, pp. e008195.

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