Sherif Nagueh, MD

Professor of Cardiology, Institute for Academic Medicine
Full Member, Research Institute
Houston Methodist
Weill Cornell Medical College


In 1996, Dr. Nagueh joined the Section of Cardiology in the Department of Medicine at the Baylor College of Medicine as an Assistant Professor. He was promoted in 2001 to an Associate Professor, and became the T.L.L Temple/William H. Spencer, MD Chair in Clinical Cardiology there in 2004. Dr. Nagueh assumed his positions at Houston Methodist in 2005.

Description of Research

Dr. Nagueh´s research career has been in the field of echocardiography. He has authored or co-authored over 100 manuscripts in peer reviewed journals and four book chapters. His research interest has been in the evaluation of diastolic function with tissue Doppler and its application in hypertrophic cardiomyopathy, particularly in patients undergoing alcohol septal ablation.

Areas Of Expertise

Alcohol septal ablation Echocardiography Diastolic function Doppler
Education & Training

Residency, Baylor College of Medicine
Clinical Fellowship
MD, University of Cairo
Active Clinical Trials

HCMR - Novel



Interobserver Variability in Applying American Society of Echocardiography/European Association of Cardiovascular Imaging 2016 Guidelines for Estimation of Left Ventricular Filling Pressure
for Diastolic Function Assessment Collaborators 2019, Circulation. Cardiovascular imaging, vol. 12, no. 1, pp. e008122.

Vein of Marshall ethanol infusion for persistent atrial fibrillation: VENUS and MARS clinical trial design
Valderrábano, M, Peterson, LE, Bunge, R, Prystash, M, Dave, A, Nagueh, S & Kleiman, N 2019, American Heart Journal, vol. 215, pp. 52-61.

The Author's Reply:
Nagueh, S 2019, JACC: Cardiovascular Imaging, vol. 12, no. 8P1.

Association of left atrial volume index and all-cause mortality in patients referred for routine cardiovascular magnetic resonance: a multicenter study
Khan, MA, Yang, EY, Zhan, Y, Judd, RM, Chan, W, Nabi, F, Heitner, JF, Kim, RJ, Klem, I, Nagueh, S & Shah, DJ 2019, Journal of Cardiovascular Magnetic Resonance, vol. 21, no. 1, 4, pp. 4.

Left Ventricular Diastolic Function: Understanding Pathophysiology, Diagnosis, and Prognosis With Echocardiography
Nagueh, S 2019, JACC: Cardiovascular Imaging.

Left atrial function: an overlooked metrics in clinical routine echocardiography
Badano, LP, Nagueh, S & Muraru, D 2019, European Journal of Heart Failure.

Understanding by General Providers of the Echocardiogram Report
Trang, A, Kampangkaew, J, Fernandes, R, Tiwana, J, Misra, A, Hamzeh, I, Blaustein, A, Aguilar, D, Shah, T, Ballantyne, C, Quiñones, MA, Nagueh, S, Dokanish, H, Virani, SS, Deswal, A, Kirkpatrick, JN & Nambi, V 2019, American Journal of Cardiology.

Impact of High Baseline Left Ventricular Filling Pressure on Transcatheter Aortic Valve Replacement Outcomes in Patients with Significant Mitral Annular Calcification
Truong, VT, Mazur, W, Palmer, C, Egnaczyk, GF, Kereiakes, DJ, Sarembock, IJ, Choo, JK, Shreenivas, S, Nagueh, S & Chung, ES 2019, Journal of the American Society of Echocardiography.

Demonstrating the Value of Outcomes in Echocardiography: Imaging-Based Registries in Improving Patient Care
Strom, JB, Tanguturi, VK, Nagueh, S, Klein, AL & Manning, WJ 2019, Journal of the American Society of Echocardiography.

Imaging for Risk Stratification of Sudden Cardiac Death in Patients With Arrhythmogenic Cardiomyopathy *
Nagueh, SF 2018, JACC: Cardiovascular Imaging, vol. 11, no. 10, pp. 1387-1389.

Cardiac Resynchronization Therapy and Dynamic Changes in Right Ventricular Function
Nagueh, S 2018, Circulation. Cardiovascular imaging, vol. 11, no. 9, pp. e008195.

Coming-of-age: The ImageGuide™ Registry at three
Tilkemeier, PL, Doukky, R, Kirkpatrick, JN, Desai, MY & Nagueh, SF 2018, Journal of Nuclear Cardiology.

Mean Right Atrial Pressure for Estimation of Left Ventricular Filling Pressure in Patients with Normal Left Ventricular Ejection Fraction: Invasive and Noninvasive Validation
Nagueh, S, Smiseth, OA, Dokainish, H, Andersen, OS, Abudiab, MM, Schutt, RC, Kumar, A, Gude, E, Sato, K, Harb, SC & Klein, AL 2018, Journal of the American Society of Echocardiography.

Effect of transcatheter aortic valve replacement on left atrial function
Truong, VT, Chung, E, Nagueh, S, Kereiakes, D, Schaaf, J, Volz, B, Ngo, TNM & Mazur, W 2018, Echocardiography.

Changes in Left Atrial Function After Transcutaneous Mitral Valve Repair
Avenatti, E, Little, SH, Barker, CM & Nagueh, SF 2018, American Journal of Cardiology.

Classification of Left Ventricular Diastolic Dysfunction and Heart Failure Diagnosis and Prognosis
Nagueh, S 2018, Journal of the American Society of Echocardiography.

Hypertrophy regression with N-acetylcysteine in hypertrophic cardiomyopathy (HALT-HCM) a randomized, placebo-controlled, double-blind pilot study
Marian, AJ, Tan, Y, Li, L, Chang, J, Syrris, P, Hessabi, M, Rahbar, MH, Willerson, JT, Cheong, BY, Liu, CY, Kleiman, N, Bluemke, DA & Nagueh, S 2018, Circulation Research, vol. 122, no. 8, pp. 1109-1118.

Reply: Issues With Estimating “Diastolic Function” and Left Ventricular Filling Pressure Using the New Guidelines
Andersen, OS, Smiseth, OA, Dokainish, H, Ha, JW, Klein, AL & Nagueh, S 2017, Journal of the American College of Cardiology, vol. 70, no. 9, pp. 1198-1199.

Detection of an Atrioesophageal Fistula on a Transthoracic Echocardiogram
Angulo, CI, El Tallawi, KC, Avenatti, E, Sukumaran, A, Quinones, M & Nagueh, SF 2017, CASE (Philadelphia, Pa.), vol. 1, no. 4, pp. 128-130.

Cardiac imaging in patients with heart failure and preserved ejection fraction
Nagueh, S, Chang, S-M, Nabi, F, Shah, DJ & Estep, JD 2017, Circulation: Cardiovascular Imaging, vol. 10, no. 9, e006547.

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