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Sasha R. Azar, PhD, MS

Assistant Professor of Surgery, Academic Institute
Assistant Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Education & Training

BS, University of California at San Diego
Publications

Potential of Ilhéus virus to emerge
Plante, KS, Plante, JA, Azar, SR, Shinde, DP, Scharton, D, Versiani, AF, Oliveira da Silva, NI, Strange, T, Sacchetto, L, Fokam, EB, Rossi, SL, Weaver, SC, Marques, RE, Nogueira, ML & Vasilakis, N 2024, , Heliyon, vol. 10, no. 6, e27934, pp. e27934. https://doi.org/10.1016/j.heliyon.2024.e27934

Trade-offs shaping transmission of sylvatic dengue and Zika viruses in monkey hosts
Hanley, KA, Cecilia, H, Azar, SR, Moehn, BA, Gass, JT, Oliveira da Silva, NI, Yu, W, Yun, R, Althouse, BM, Vasilakis, N & Rossi, SL 2024, , Nature Communications, vol. 15, no. 1, 2682, pp. 2682. https://doi.org/10.1038/s41467-024-46810-x

Real-time imaging of dynamic tissues
Nichols, JE & Azar, SR 2023, , Nature Methods, vol. 20, no. 11, pp. 1631-1632. https://doi.org/10.1038/s41592-023-02047-y

The anti-immune dengue subgenomic flaviviral RNA is present in vesicles in mosquito saliva and is associated with increased infectivity
Yeh, SC, Strilets, T, Tan, WL, Castillo, D, Medkour, H, Rey-Cadilhac, F, Serrato-Pomar, IM, Rachenne, F, Chowdhury, A, Chuo, V, Azar, SR, Singh, MK, Hamel, R, Missé, D, Kini, RM, Kenney, LJ, Vasilakis, N, Marti-Renom, MA, Nir, G, Pompon, J & Garcia-Blanco, MA 2023, , PLoS pathogens, vol. 19, no. 3, e1011224, pp. e1011224. https://doi.org/10.1371/JOURNAL.PPAT.1011224

Recombinant vesicular stomatitis vaccine against nipah virus has a favorable safety profile: Model for assessment of live vaccines with neurotropic potential
Monath, TP, Nichols, R, Tussey, L, Scappaticci, K, Pullano, TG, Whiteman, MD, Vasilakis, N, Rossi, SL, Campos, RK, Azar, SR, Spratt, HM, Seaton, BL, Archambault, WT, Costecalde, YV, Moore, EH, Hawks, RJ & Fusco, J 2022, , PLoS pathogens, vol. 18, no. 6, e1010658, pp. e1010658. https://doi.org/10.1371/journal.ppat.1010658

Aedes aegypti Shows Increased Susceptibility to Zika Virus via Both In Vitro and In Vivo Models of Type II Diabetes
Azar, SR, Campos, RK, Yun, R, Strange, T, Rossi, SL, Hanley, KA, Vasilakis, N & Weaver, SC 2022, , Viruses, vol. 14, no. 4, 665. https://doi.org/10.3390/v14040665

Venezuelan Equine Encephalitis Virus V3526 Vaccine RNA-Dependent RNA Polymerase Mutants Increase Vaccine Safety Through Restricted Tissue Tropism in a Murine Model
Haines, CA, Campos, RK, Azar, SR, Warmbrod, KL, Kautz, TF, Forrester, NL & Rossi, SL 2022, , Zoonoses (Burlington, Mass.), vol. 2. https://doi.org/10.15212/zoonoses-2021-0016

Venezuelan Equine Encephalitis Virus V3526 Vaccine RNA-Dependent RNA Polymerase Mutants Increase Vaccine Safety Through Restricted Tissue Tropism in a Mouse Model
Haines, CA, Campos, RK, Azar, SR, Warmbrod, KL, Kautz, TF, Forrester, NL & Rossi, SL 2022, , Zoonoses (Ireland), vol. 2, no. 1, 2. https://doi.org/10.15212/ZOONOSES-2021-0016

A single dose of ChAdOx1 Chik vaccine induces neutralizing antibodies against four chikungunya virus lineages in a phase 1 clinical trial
Folegatti, PM, Harrison, K, Preciado-Llanes, L, Lopez, FR, Bittaye, M, Kim, YC, Flaxman, A, Bellamy, D, Makinson, R, Sheridan, J, Azar, SR, Campos, RK, Tilley, M, Tran, N, Jenkin, D, Poulton, I, Lawrie, A, Roberts, R, Berrie, E, Rossi, SL, Hill, A, Ewer, KJ & Reyes-Sandoval, A 2021, , Nature Communications, vol. 12, no. 1, 4636. https://doi.org/10.1038/s41467-021-24906-y

Role of mutational reversions and fitness restoration in Zika virus spread to the Americas
Liu, J, Liu, Y, Shan, C, Nunes, BTD, Yun, R, Haller, SL, Rafael, GH, Azar, SR, Andersen, CR, Plante, K, Vasilakis, N, Shi, PY & Weaver, SC 2021, , Nature Communications, vol. 12, no. 1, 595. https://doi.org/10.1038/s41467-020-20747-3

Sars-cov-2 infects hamster testes
Campos, RK, Camargos, VN, Azar, SR, Haines, CA, Eyzaguirre, EJ & Rossi, SL 2021, , Microorganisms, vol. 9, no. 6, 1318. https://doi.org/10.3390/microorganisms9061318

Evolution of resistance to fluoroquinolones by dengue virus serotype 4 provides insight into mechanism of action and consequences for viral fitness
Scroggs, SLP, Gass, JT, Chinnasamy, R, Widen, SG, Azar, SR, Rossi, SL, Arterburn, JB, Vasilakis, N & Hanley, KA 2021, , Virology, vol. 552, pp. 94-106. https://doi.org/10.1016/j.virol.2020.09.004

Adenoviral-Vectored Mayaro and Chikungunya Virus Vaccine Candidates Afford Partial Cross-Protection From Lethal Challenge in A129 Mouse Model
Kroon Campos, R, Preciado-Llanes, L, Azar, SR, Kim, YC, Brandon, O, López-Camacho, C, Reyes-Sandoval, A & Rossi, SL 2020, , Frontiers in immunology, vol. 11, 591885. https://doi.org/10.3389/fimmu.2020.591885

Envelope protein ubiquitination drives entry and pathogenesis of Zika virus
Giraldo, MI, Xia, H, Aguilera-Aguirre, L, Hage, A, van Tol, S, Shan, C, Xie, X, Sturdevant, GL, Robertson, SJ, McNally, KL, Meade-White, K, Azar, SR, Rossi, SL, Maury, W, Woodson, M, Ramage, H, Johnson, JR, Krogan, NJ, Morais, MC, Best, SM, Shi, PY & Rajsbaum, R 2020, , Nature, vol. 585, no. 7825, pp. 414-419. https://doi.org/10.1038/s41586-020-2457-8

Old drugs with new tricks: Efficacy of fluoroquinolones to suppress replication of flaviviruses
Scroggs, SLP, Andrade, CC, Chinnasamy, R, Azar, SR, Schirtzinger, EE, Garcia, EI, Arterburn, JB, Hanley, KA & Rossi, SL 2020, , Viruses, vol. 12, no. 9, 1022. https://doi.org/10.3390/v12091022

Epidemic alphaviruses: Ecology, emergence and outbreaks
Azar, SR, Campos, RK, Bergren, NA, Camargos, VN & Rossi, SL 2020, , Microorganisms, vol. 8, no. 8, 1167, pp. 1-35. https://doi.org/10.3390/microorganisms8081167

A Zika virus envelope mutation preceding the 2015 epidemic enhances virulence and fitness for transmission
Shan, C, Xia, H, Haller, SL, Azar, SR, Liu, Y, Liu, J, Muruato, AE, Chen, R, Rossi, SL, Wakamiya, M, Vasilakis, N, Pei, R, Fontes-Garfias, CR, Singh, SK, Xie, X, Weaver, SC & Shi, PY 2020, , Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 33, pp. 20190-20197. https://doi.org/10.1073/PNAS.2005722117

Identification of mosquito bloodmeals collected in diverse habitats in Malaysian borneo using COI barcoding
Young, KI, Medwid, JT, Azar, SR, Huff, RM, Drumm, H, Coffey, LL, Jason Pitts, R, Buenemann, M, Vasilakis, N, Perera, D & Hanley, KA 2020, , Tropical Medicine and Infectious Disease, vol. 5, no. 2, 51. https://doi.org/10.3390/tropicalmed5020051

Vector competence analyses on aedes aegypti mosquitoes using zika virus
Azar, SR & Weaver, SC 2020, , Journal of Visualized Experiments, vol. 2020, no. 159, e61112, pp. 1-7. https://doi.org/10.3791/61112

Zika Virus (Flaviviridae)
Vasilakis, N, Rossi, SL, Azar, SR, Cisneros, IE, Estofolete, CF & Nogueira, ML 2020, . in Encyclopedia of Virology: Volume 1-5, Fourth Edition. vol. 1-5, Elsevier, pp. 899-909. https://doi.org/10.1016/B978-0-12-814515-9.00026-6

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