Pedro T. Ramirez, MD, FACOG

Chair, Department of Obstetrics & Gynecology
Houston Methodist


Biography

Dr. Pedro T. Ramirez is Chair of the Department of Obstetrics and Gynecology at Houston Methodist Hospital. He completed his residency training at Columbia Presbyterian Medical Center in New York City. He then completed a Gynecologic Oncology Fellowship at MD Anderson Cancer Center. After completion he remained on faculty there for 25 years. He was also the recipient of the David M. Gershenson Distinguished Professor in Ovarian Cancer Research Endowment and of the Randall Prize for Excellence in Cancer Treatment. 
Dr. Ramirez is also the Editor-in-Chief of the International Journal of Gynecological Cancer. He has published over 300 manuscripts in peer-reviewed journals, including the New England Journal of Medicine and has published a total of 19 book chapters. In addition, he is the Editor for the textbook titled Principles of Gynecologic Oncology Surgery. He is also Co-Editor of a textbook published in 2022 titled The ERAS Society Handbook for Obstetrics & Gynecology. 

Description of Research

Dr. Ramirez was the Principal Investigator in the LACC Trial: A Phase III Randomized Clinical Trial of Laparoscopic or Robotic Radical Hysterectomy versus Abdominal Radical Hysterectomy in Patients with Early Stage Cervical Cancer. This landmark study showed that minimally invasive radical hysterectomy in patients with early-stage cervical cancer was associated with a worse disease-free survival, recurrence rate, progression-free survival, and overall survival when compared to the open approach. These results have been practice changing and all guidelines have changed to the open approach as the standard of care when performing radical hysterectomy. The study was published in The New England Journal of Medicine. Most recently, Dr. Ramirez was made member of the IDEAL Council at Oxford University in England. In this role, he collaborates with leaders in the field of surgical research on developing strategies to integrate innovative surgical tools to the standard of care practice in patients with gynecological cancers.

Publications

Innovation in gynaecological cancer: highlighting global disparities
Kyrgiou, M, Bowden, S, Denny, L, Fagotti, A, Abu-Rustum, NR, Ramirez, PT & Querleu, D 2024, , The Lancet Oncology, vol. 25, no. 4, pp. 425-430. https://doi.org/10.1016/S1470-2045(24)00137-2

ESGO–ESMO–ESP consensus conference recommendations on ovarian cancer: pathology and molecular biology and early, advanced and recurrent disease
Ledermann, JA, Matias-Guiu, X, Amant, F, Concin, N, Davidson, B, Fotopoulou, C, González-Martin, A, Gourley, C, Leary, A, Lorusso, D, Banerjee, S, Chiva, L, Cibula, D, Colombo, N, Croce, S, Eriksson, AG, Falandry, C, Fischerova, D, Harter, P, Joly, F, Lazaro, C, Lok, C, Mahner, S, Marmé, F, Marth, C, McCluggage, WG, McNeish, IA, Morice, P, Nicum, S, Oaknin, A, Pérez-Fidalgo, JA, Pignata, S, Ramirez, PT, Ray-Coquard, I, Romero, I, Scambia, G, Sehouli, J, Shapira-Frommer, R, Sundar, S, Tan, DSP, Taskiran, C, van Driel, WJ, Vergote, I, Planchamp, F, Sessa, C & Fagotti, A 2024, , Annals of Oncology, vol. 35, no. 3, pp. 248-266. https://doi.org/10.1016/j.annonc.2023.11.015

When Less Is More — The Importance of Patient Selection
Ramirez, PT 2024, , New England Journal of Medicine, vol. 390, no. 9, pp. 861-862. https://doi.org/10.1056/NEJMe2400423

Consensus on surgical technique for sentinel lymph node dissection in cervical cancer
Bizzarri, N, Obermair, A, Hsu, HC, Chacon, E, Collins, A, Tsibulak, I, Mutombo, A, Abu-Rustum, NR, Balaya, V, Buda, A, Cibula, D, Covens, A, Fanfani, F, Ferron, G, Frumovitz, M, Guani, B, Kocian, R, Kohler, C, Leblanc, E, Lecuru, F, Leitao, MM, Mathevet, P, Mueller, MD, Papadia, A, Pareja, R, Plante, M, Querleu, D, Scambia, G, Tanner, E, Zapardiel, I, Garcia, JR & Ramirez, PT 2024, , International Journal of Gynecological Cancer, vol. 34, no. 4, pp. 504-509. https://doi.org/10.1136/ijgc-2023-005151

Response to: Correspondence on “Complications of HIPEC for ovarian cancer surgery: evaluation over two time periods” by Lavoue et al
Santana, BN, Viveros-Carreño, D, Viveros-Carreño, DJ & Ramirez, PT 2024, , International Journal of Gynecological Cancer. https://doi.org/10.1136/ijgc-2024-005431

The IDEAL framework for surgical robotics: development, comparative evaluation and long-term monitoring
Marcus, HJ, Ramirez, PT, Khan, DZ, Layard Horsfall, H, Hanrahan, JG, Williams, SC, Beard, DJ, Bhat, R, Catchpole, K, Cook, A, Hutchison, K, Martin, J, Melvin, T, Stoyanov, D, Rovers, M, Raison, N, Dasgupta, P, Noonan, D, Stocken, D, Sturt, G, Vanhoestenberghe, A, Vasey, B & McCulloch, P 2024, , Nature Medicine. https://doi.org/10.1038/s41591-023-02732-7

Recurrence After Biopsy-Confirmed Cervical High-Grade Intraepithelial Lesion Followed by Negative Conization: A Systematic Review and Meta-analysis
Viveros-Carreño, D, Mora-Soto, N, Rodríguez, J, Rauh-Hain, JA, Ramírez, PT, López Varón, M, Krause, KJ, Grillo-Ardila, CF, Jeronimo, J & Pareja, R 2024, , Journal of Lower Genital Tract Disease, vol. 28, no. 1, pp. 26-31. https://doi.org/10.1097/LGT.0000000000000779

Author Correction: The IDEAL framework for surgical robotics: development, comparative evaluation and long-term monitoring
The IDEAL Robotics Colloquium 2024, , Nature Medicine, vol. 30, pp. 1213. https://doi.org/10.1038/s41591-024-02836-8

Hypertensive Disorders of Pregnancy
Newman, C, Petruzzi, V, Ramirez, PT & Hobday, C 2024, , Methodist DeBakey cardiovascular journal, vol. 20, no. 2, pp. 4-12. https://doi.org/10.14797/mdcvj.1305

Fertility-sparing surgery vs standard surgery for early-stage cervical cancer: difference in 5-year life expectancy by tumor size
Jorgensen, KA, Agusti, N, Wu, CF, Kanbergs, A, Pareja, R, Ramirez, PT, Rauh-Hain, JA & Melamed, A 2024, , American Journal of Obstetrics and Gynecology, vol. 230, no. 6, pp. 663.e1-663.e13. https://doi.org/10.1016/j.ajog.2024.02.012

Sentinel lymph node mapping with indocyanine green using SPY-PHI in open radical hysterectomy or trachelectomy
Fernandez, MA, Clark, HD, Iniesta, MD, Munsell, MF, Frumovitz, M & Ramirez, PT 2023, , International Journal of Gynecological Cancer, vol. 34, no. 1, pp. 28-34. https://doi.org/10.1136/ijgc-2023-004787

Cardiophrenic lymph nodes in advanced ovarian cancer
Agusti, N, Bonaldo, G, Kahn, RM, Rosati, A, Nachira, D, Pan, TL, Mburu, A, Kochiashvili, G, Paredes, P, Hsu, HC, Davies-Oliveira, J & Ramirez, PT 2023, , International Journal of Gynecological Cancer, vol. 34, no. 1, pp. 150-158. https://doi.org/10.1136/ijgc-2023-004963

Combination of hormonal-based therapy in endometrial cancer: ready for prime time
Santía, MC, Vilches, JC & Ramirez, PT 2023, , International Journal of Gynecological Cancer, vol. 33, no. 11, pp. 1682-1683. https://doi.org/10.1136/ijgc-2023-005031

MILACC study: could undetected lymph node micrometastases have impacted recurrence rate in the LACC trial?
Nitecki, R, Ramirez, PT, Dundr, P, Nemejcova, K, Ribeiro, R, Vieira Gomes, MT, Schmidt, RL, Bedoya, L, Isla, DO, Pareja, R, Rendón Pereira, GJ, Lopez, A, Kushner, D & Cibula, D 2023, , International Journal of Gynecological Cancer, vol. 33, no. 11, pp. 1684-1689. https://doi.org/10.1136/ijgc-2023-004711

Gestational choriocarcinoma
Bogani, G, Ray-Coquard, I, Mutch, D, Vergote, I, Ramirez, PT, Prat, J, Concin, N, Li Ngoi, NY, Coleman, RL, Enomoto, T, Takehara, K, Denys, H, Lorusso, D, Takano, M, Sagae, S, Wimberger, P, Segev, Y, Kim, SI, Kim, JW, Herrera, F, Mariani, A, Brooks, RA, Tan, D, Paolini, B, Chiappa, V, Longo, M, Raspagliesi, F, Panici, PB, Donato, VD, Caruso, G, Colombo, N, Pignata, S, Zannoni, G, Scambia, G & Monk, BJ 2023, , International Journal of Gynecological Cancer, vol. 33, no. 10, pp. 1504-1514. https://doi.org/10.1136/ijgc-2023-004704

Diagnostic accuracy of sentinel lymph node frozen section analysis in patients with early-stage cervical cancer: A systematic review and meta-analysis
Agustí, N, Viveros-Carreño, D, Mora-Soto, N, Ramírez, PT, Rauh-Hain, A, Wu, CF, Rodríguez, J, Grillo-Ardila, CF, Salazar, C, Jorgensen, K, Segarra-Vidal, B, Chacón, E, Melamed, A & Pareja, R 2023, , Gynecologic oncology, vol. 177, pp. 157-164. https://doi.org/10.1016/j.ygyno.2023.08.019

Survival after sentinel node biopsy alone in early-stage cervical cancer: A systematic review
Mauro, J, Viveros-Carreño, D, Vizzielli, G, De Ponti, E, Fanfani, F, Ramirez, PT & Buda, A 2023, , International Journal of Gynecological Cancer, vol. 33, no. 9, pp. 1370-1375. https://doi.org/10.1136/ijgc-2023-004692

Isolated nodal recurrence in endometrial cancer: Not so common and very salvageable
Yates, EM & Ramirez, PT 2023, , International Journal of Gynecological Cancer, vol. 33, no. 8, pp. 1179-1180. https://doi.org/10.1136/ijgc-2023-004771

Enhanced Recovery After Surgery (ERAS®) Society Guidelines for Gynecologic Oncology: Addressing Implementation Challenges - 2023 Update
Nelson, G, Fotopoulou, C, Taylor, J, Glaser, G, Bakkum-Gamez, J, Meyer, LA, Stone, R, Mena, G, Elias, KM, Altman, AD, Bisch, SP, Ramirez, PT & Dowdy, SC 2023, , Obstetrical and Gynecological Survey, vol. 78, no. 8, pp. 476-477. https://doi.org/10.1097/01.ogx.0000967024.88312.e0

Definitive pelvic radiotherapy for patients with newly diagnosed stage IVB cervical cancer: A systematic review
Viveros-Carreño, D, Vieira-Serna, S, Grillo - Ardila, CF, Rodriguez, J, Mora-Soto, N, Jhingran, A, Ramirez, PT & Pareja, R 2023, , International Journal of Gynecological Cancer, vol. 33, no. 7, pp. 1057-1062. https://doi.org/10.1136/ijgc-2023-004465