Pavla Brachova

Pavla Brachova, PhD

Adjunct Assistant Professor of Cardiovascular Sciences, Academic Institute
Assistant Affiliate Member, Research Institute
Houston Methodist


Publications

Loss of Cnot6l impairs inosine RNA modifications in mouse oocytes
Brachova, P, Alvarez, NS & Christenson, LK 2021, , International journal of molecular sciences, vol. 22, no. 3, 1191, pp. 1-17. https://doi.org/10.3390/ijms22031191

Inosine RNA modifications are enriched at the codon wobble position in mouse oocytes and eggs
Brachova, P, Alvarez, NS, Hong, X, Gunewardena, S, Vincent, KA, Latham, KE & Christenson, LK 2019, , Biology of Reproduction, vol. 101, no. 5, pp. 938-949. https://doi.org/10.1093/biolre/ioz130

Cytidine deaminase Apobec3a induction in fallopian epithelium after exposure to follicular fluid
Brachova, P, Alvarez, NS, Van Voorhis, BJ & Christenson, LK 2017, , Gynecologic oncology, vol. 145, no. 3, pp. 577-583. https://doi.org/10.1016/j.ygyno.2017.02.017

TP53 oncomorphic mutations predict resistance to platinum- and taxane-based standard chemotherapy in patients diagnosed with advanced serous ovarian carcinoma
Brachova, P, Mueting, SR, Carlson, MJ, Goodheart, MJ, Button, AM, Mott, SL, Dai, D, Thiel, KW, Devor, EJ & Leslie, KK 2015, , International Journal of Oncology, vol. 46, no. 2, pp. 607-618. https://doi.org/10.3892/ijo.2014.2747

MicroRNA regulation of endocrine 6 functions in the ovary
Brachova, P, Hung, WT, McGinnis, LK & Christenson, LK 2015, . in Post-Transcriptional Mechanisms in Endocrine Regulation. Springer International Publishing, pp. 109-127. https://doi.org/10.1007/978-3-319-25124-0_6

The consequence of oncomorphic TP53 mutations in ovarian cancer
Brachova, P, Thiel, KW & Leslie, KK 2013, , International journal of molecular sciences, vol. 14, no. 9, pp. 19257-19275. https://doi.org/10.3390/ijms140919257

Induction of mitotic cell death by overriding G2/M checkpoint in endometrial cancer cells with non-functional p53
Meng, X, Laidler, LL, Kosmacek, EA, Yang, S, Xiong, Z, Zhu, D, Wang, X, Dai, D, Zhang, Y, Wang, X, Brachova, P, Albitar, L, Liu, D, Ianzini, F, MacKey, MA & Leslie, KK 2013, , Gynecologic oncology, vol. 128, no. 3, pp. 461-469. https://doi.org/10.1016/j.ygyno.2012.11.004

Cytoplasmic metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein
Meng, X, Zhu, D, Yang, S, Wang, X, Xiong, Z, Zhang, Y, Brachova, P & Leslie, KK 2012, , Journal of Biological Chemistry, vol. 287, no. 7, pp. 4485-4491. https://doi.org/10.1074/jbc.C111.291518

Knockdown of mtdh sensitizes endometrial cancer cells to cell death induction by death receptor ligand trail and HDAC inhibitor LBH589 Co-treatment
Meng, X, Brachova, P, Yang, S, Xiong, Z, Zhang, Y, Thiel, KW & Leslie, KK 2011, , PLoS ONE, vol. 6, no. 6, e20920. https://doi.org/10.1371/journal.pone.0020920