Omonike Olaleye

Omonike Olaleye, PhD

Assistant Affiliate Member, Research Institute
Houston Methodist


Publications

Anti-Tuberculosis Potential of OJT008 against Active and Multi-Drug-Resistant Mycobacterium Tuberculosis: In Silico and In Vitro Inhibition of Methionine Aminopeptidase
Onyenaka, C, Idowu, KA, Ha, NP, Graviss, EA & Olaleye, OA 2023, , International journal of molecular sciences, vol. 24, no. 24, 17142. https://doi.org/10.3390/ijms242417142

Racial Disparities in Preterm Birth among Pregnant Women with Obesity
Egbejimi, A, Ajewole, V, Dongarwar, D, Kaur, M, Phillips, M, Liang, J, Fadel, M, Lota, L, Simon, J, Otule, M, Taylor, K, Oguibe, GS, Salihu, HM & Olaleye, O 2023, , Southern Medical Journal, vol. 116, no. 6, pp. 471-477. https://doi.org/10.14423/SMJ.0000000000001569

Diabetes in pregnancy and risk of near-miss, maternal mortality and foetal outcomes in the USA: A retrospective cross-sectional analysis
Tavera, G, Dongarwar, D, Salemi, JL, Akindela, O, Osazuwa, I, Akpan, EB, Okolie, U, Johnson, M, Spooner, KK, Akpan, UI, Yusuf, KK, Chukwudum, C, Salihu, HM & Olaleye, OA 2022, , Journal of Public Health (United Kingdom), vol. 44, no. 3, pp. 549-557. https://doi.org/10.1093/pubmed/fdab117

Success of Maternal and Child Health Pipeline Training Programs: Alumni Survey Results
Fernandes, P, Wang, K, Timmerman, J, Reyes, A, Holmes, F, Olaleye, OA, Salihu, HM, Moerchen, VA, Belcher, HME, Copeland-Linder, N, Noble, CA, Vamos, CA, Armstrong, A, Waters, CR, Long-White, D, Brown, C, Reddy, MM & Kuo, A 2022, , Maternal and Child Health Journal, vol. 26, no. Suppl 1, pp. 69-77. https://doi.org/10.1007/s10995-022-03458-7

Inhibitory mechanism of Ambroxol and Bromhexine Hydrochlorides as potent blockers of molecular interaction between SARS-CoV-2 spike protein and human angiotensin-converting Enzyme-2
Kehinde, IA, Egbejimi, A, Kaur, M, Onyenaka, C, Adebusuyi, T & Olaleye, OA 2022, , Journal of Molecular Graphics and Modelling, vol. 114, 108201, pp. 108201. https://doi.org/10.1016/j.jmgm.2022.108201

Micromolar Concentrations of Methionine Aminopeptidase Inhibitor has Little Cytotoxic Effect on Cancerous and Non-Cancerous Mammalian Cells
Croes, A, Clymer, J, Loveless, J, Nguyen, C, Tawfiq, H, Romo, C, Patel, N, Flores, R, Gomez, J, Alvarez, M, Olaleye, O & Rosell, R 2022, , FASEB journal : official publication of the Federation of American Societies for Experimental Biology, vol. 36. https://doi.org/10.1096/fasebj.2022.36.S1.R3000

Metabolite Identification of a Novel Anti-Leishmanial Agent OJT007 in Rat Liver Microsomes Using LC-MS/MS
Nigro, MER, Du, T, Gao, S, Kaur, M, Xie, H, Olaleye, OA & Liang, D 2022, , Molecules, vol. 27, no. 9, 2854. https://doi.org/10.3390/molecules27092854

Inhibitory mechanism of clioquinol and its derivatives at the exopeptidase site of human angiotensin-converting enzyme-2 and receptor binding domain of SARS-CoV-2 viral spike
Kehinde, IA, Egbeyemi, A, Kaur, M, Onyenaka, C, Adebusuyi, T & Olaleye, OA 2023, , Journal of Biomolecular Structure and Dynamics, vol. 41, no. 7, pp. 2992-3001. https://doi.org/10.1080/07391102.2022.2043938

MCH Pipeline Training Program: Connecting with Academia to Build Capacity Through Mentoring
Belcher, HME, Copeland-Linder, N, Stone, J, Waters, CR, Kuo, A, Moerchen, V, Olaleye, O, Salihu, HM, Vamos, C, Brown, C & Reddy, MM 2022, , Maternal and Child Health Journal, vol. 26, no. Suppl 1, pp. 37-43. https://doi.org/10.1007/s10995-022-03397-3

Success of Maternal and Child Health Pipeline Training Programs: Alumni Survey Results
Fernandes, P, Wang, K, Timmerman, J, Reyes, A, Holmes, F, Olaleye, OA, Salihu, HM, Moerchen, VA, Belcher, HME, Copeland-Linder, N, Noble, CA, Vamos, CA, Armstrong, A, Waters, CR, Long-White, D, Brown, C, Reddy, MM & Kuo, A 2022, , Maternal and Child Health Journal, vol. 26, no. 7, pp. 1415-1423. https://doi.org/10.1007/s10995-021-03370-6

Maternal and Child Health Pipeline Training Programs: A Description of Training Across 6 Funded Programs
Moerchen, V, Taylor-DeOliveira, L, Dietrich, M, Armstrong, A, Azeredo, J, Belcher, H, Copeland-Linder, N, Fernandes, P, Kuo, A, Noble, C, Olaleye, O, Salihu, H, Waters, CR, Brown, C & Reddy, MM 2022, , Maternal and Child Health Journal, vol. 26, no. Suppl 1, pp. 137-146. https://doi.org/10.1007/s10995-022-03375-9

HRSA-Funded MCH Pipeline Training Program: Advancing the MCH Pipeline and Workforce Through Research Collaborations
Olaleye, OA, Dongarwar, D, Salihu, HM, Adu-Gyamfi, S, Kaur, M, Egbejimi, A, Moerchen, VA, Belcher, HME, Holmes, F, Kuo, A, Copeland-Linder, N, Noble, CA, Vamos, CA, Waters, CR, Brown, CM & Reddy, MM 2022, , Maternal and Child Health Journal, vol. 26, no. Suppl 1, pp. 147-155. https://doi.org/10.1007/s10995-022-03439-w

A computational evaluation of structural stability of omicron and delta mutations of SARS-CoV-2 spike proteins and human ACE-2 interactions
Idowu, KA, Onyenaka, C & Olaleye, OA 2022, , Informatics in Medicine Unlocked, vol. 33, 101074, pp. 101074. https://doi.org/10.1016/j.imu.2022.101074

Impact of prophylactic antimalarials in pregnant women living with Human Immunodeficiency Virus on birth outcomes in Botswana
Olaleye, OA, Zash, R, Diseko, M, Mayondi, G, Mabuta, J, Lockman, S, Melton, ML, Mmalane, M, Makhema, J & Shapiro, RL 2022, , Tropical Medicine and International Health, vol. 27, no. 11, pp. 990-998. https://doi.org/10.1111/tmi.13823

Racial and Ethnic Disparities in Stillbirth among Pregnant Women with Obesity
Dongarwar, D, Ajewole, V, Spooner, KK, Tran, V, Adebusuyi, T, Onyenaka, C, Bakare, O, Emeh, C, Baines, K, Boua, D, Mossi, Y, Egbejimi, A, Ibrahim, S, Olaleye, O & Salihu, HM 2024, , American Journal of Perinatology, vol. 41, pp. E2138-E2144. https://doi.org/10.1055/a-2099-8494

Development and validation of a sensitive, specific and reproducible uplc-ms/ms method for the quantification of ojt007, a novel anti-leishmanial agent: Application to a pharmacokinetic study
Nigro, MR, Ma, J, Awosemo, OT, Xie, H, Olaleye, OA & Liang, D 2021, , International journal of environmental research and public health, vol. 18, no. 9, 4624. https://doi.org/10.3390/ijerph18094624

Discovery of Clioquinol and analogues as novel inhibitors of Severe Acute Respiratory Syndrome Coronavirus 2 infection, ACE2 and ACE2 - Spike protein interaction in vitro
Olaleye, OA, Kaur, M, Onyenaka, C & Adebusuyi, T 2021, , Heliyon, vol. 7, no. 3, e06426, pp. e06426. https://doi.org/10.1016/j.heliyon.2021.e06426

Temporal trends of gestational malaria in the United States
Alexander, J, Dongarwar, D, Oduguwa, E, Varnado, L, Adenote, A, Bailey, J, Ezeudu, C, Nelson, P, Shavers, A, Telufusi, A, Spooner, KK, Salemi, JL, Olaleye, OA & Salihu, HM 2020, , Parasite Epidemiology and Control, vol. 11, e00191. https://doi.org/10.1016/j.parepi.2020.e00191

Trends and associated characteristics for Chagas disease among women of reproductive age in the United States, 2002 to 2017
Ikedionwu, C, Dongarwar, D, Kaur, M, Nunez, L, Awazi, A, Mallet, J, Kennedy, KS, Cano, M, Dike, C, Okwudi, J, Stewart, J, Igwegbe, D, Estes, FG, Spooner, KK, Salemi, JL, Salihu, HM & Olaleye, OA 2020, , Parasite Epidemiology and Control, vol. 11, e00167. https://doi.org/10.1016/j.parepi.2020.e00167

Opioid Use among HIV-Positive Pregnant Women and the Risk for Maternal-Fetal Complications
Nguyen, NH, Le, EN, Mbah, VO, Welsh, EB, Daas, R, Spooner, KK, Salemi, JL, Olaleye, OA & Salihu, HM 2020, , Southern Medical Journal, vol. 113, no. 6, pp. 292-297. https://doi.org/10.14423/SMJ.0000000000001105

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