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Omaima Sabek, PhD

Associate Research Professor of Surgery, Academic Institute
Associate Research Member, Research Institute
Houston Methodist
Weill Cornell Medical College


After completion of her postdoctoral training in 2005, Dr. Sabek received dual appointments as an Assistant Professor in the College of Nursing and Department of Surgery at the University of Tennessee in Memphis, Tennessee. She has collaborated on several NIH-funded research grants and published over 30 peer-reviewed papers. Dr. Sabek joined The Methodist Hospital Research Institute in 2007.

Description of Research

Dr. Sabek´s research focuses on islet cell transplantation, and specifically, the surrogate markers for prediction of long-term transplantation outcomes. She also aims to improve transplantation outcomes through the development and validation of improved techniques for islet recovery, isolation, engraftment, and post-transplant functioning/preservation. Dr. Sabek also conducts studies investigating potential biomarkers of allograft rejection.

Areas Of Expertise

Diabetes Islet cell transplantation Functional Genomics Allograft rejection Osteocalcin
Education & Training

Postdoctoral Fellowship, Department of Biochemistry, University of Tennessee, Memphis, TN
PhD, University College London

Serum C-peptide and osteocalcin levels in children with recently diagnosed diabetes
Sabek, OM, Redondo, MJ, Nguyen, DT, Beamish, CA, Fraga, DW, Hampe, CS, Mulukutla, SN, Graviss, EA & Gaber, AO 2020, Endocrinology, diabetes & metabolism, vol. 3, no. 1, pp. e00104.

Cross-sectional evaluation of the relationship between Vitamin D status and supplement use across levels of kidney function in adults
Moore, LW, Suki, WN, Lunsford, KE, Sabek, O, Knight, RJ & Gaber, AO 2019, BMJ open, vol. 9, no. 2, e022471.

Variability in endocrine cell identity in patients with chronic pancreatitis undergoing islet autotransplantation
Beamish, C, Gaber, AO, Afshar, S, Fraga, DW, Hamilton, DJ & Sabek, O 2018, American Journal of Transplantation.

Echocardiography Differentiates Lethally Irradiated Whole-Body From Partial-Body Exposed Rats
Inoue, T, Zawaski, JA, Sheehan, V, Kanne, C, Paikari, A, Kaffes, CC, sarkar, P, Sabek, O & Waleed Gaber, M 2018, Frontiers in cardiovascular medicine, vol. 5, 138, pp. 1-8.

Exercise ameliorates neurocognitive impairments in a translational model of pediatric radiotherapy
Sahnoune, I, Inoue, T, Kesler, SR, Rodgers, SP, Sabek, OM, Pedersen, SE, Zawaski, JA, Nelson, KH, Douglas Ris, M, Leigh Leasure, J & Waleed Gaber, M 2018, Neuro-Oncology, vol. 20, no. 5, pp. 695-704.

A Cross-sectional Evaluation of the Relationship Between Vitamin D Status and Supplement Use Across Levels of Kidney Function in Adults: Vitamin D Status, Supplements, and Kidney function
Moore, LW, Suki, WN, Lunsford, KE, Sabek, O, Knight, RJ & Gaber, AO 2018, BMJ.

Induction of IAPP amyloid deposition and associated diabetic abnormalities by a prion-like mechanism
Mukherjee, A, Morales-Scheihing, D, Salvadores, N, Moreno-Gonzalez, I, Gonzalez, C, Taylor-Presse, K, Mendez, N, Shahnawaz, M, Gaber, AO, Sabek, OM, Fraga, DW & Soto, C 2017, The Journal of experimental medicine.

Induction of IAPP amyloid deposition and associated diabetic abnormalities by a prion-like mechanism
Sabek, O 2017, Journal of Experimental Medicine.

Effect of Brain Tumor Presence During Radiation on Tissue Toxicity: Transcriptomic and Metabolic Changes
Zawaski, JA, Sabek, OM, Voicu, H, Eastwood Leung, H-C & Gaber, MW 2017, International Journal of Radiation Oncology Biology Physics.

Effect of Brain Tumor Presence During Radiation on Tissue Toxicity: Transcriptomic and Metabolic Changes.
Sabek, O 2017, International Journal of Radiation Oncology Biology Physics, pp. 1.

Investigating the Abscopal Effects of Radioablation on Shielded Bone Marrow in Rodent Models Using Multimodality Imaging
Afshar, SF, Zawaski, JA, Inoue, T, Rendon, DA, Zieske, AW, Punia, JN, Sabek, OM & Gaber, MW 2017, Radiation Research, vol. 188, no. 1, pp. 56-65.

Serum undercarboxylated osteocalcin correlates with hemoglobin A1c in children with recently diagnosed pediatric diabetes
Redondo, MJ, Shirkey, BA, Fraga, DW, Gaber, AO & Sabek, OM 2017, Pediatric Diabetes, vol. 18, no. 8, pp. 869-873.

3D Printed Vascularized Device for Subcutaneous Transplantation of Human Islets
Farina, M, Ballerini, A, Fraga, DW, Nicolov, E, Hogan, M, Demarchi, D, Scaglione, F, Sabek, OM, Horner, P, Thekkedath, U, Gaber, OA & Grattoni, A 2017, Biotechnology Journal.

Imaging Radiation-Induced Gastrointestinal, Bone Marrow Injury and Recovery Kinetics Using 18F-FDG PET
Tang, TT, Rendon, DA, Afshar, SF, Kaffes, CK, Sabek, OM & Gaber, MW 2017, PLoS ONE, vol. 12, no. 1, pp. e0169082.

Advancing islet transplantation: from donor to engraftment
Sabek, O 2016, . Springer US.

Sustained zero-order delivery of GC-1 from a nanochannel membrane device alleviates metabolic syndrome
Filgueira, CS, Nicolov, E, Hood, RL, Ballerini, A, Garcia-Huidobro, J, Lin, JZ, Fraga, D, Webb, P, Sabek, O, Gaber, AO, Phillips, KJ & Grattoni, A 2016, International Journal of Obesity.

Three-dimensional printed polymeric system to encapsulate human mesenchymal stem cells differentiated into islet-like insulin-producing aggregates for diabetes treatment
Sabek, O, Farina, M, Fraga, DW, Afshar, S, Ballerini, A, Filgueira, CS, Thekkedath, UR, Grattoni, A & Gaber, AO 2016, Journal of Tissue Engineering, vol. 7.

Mapping radiation injury and recovery in bone marrow using 18F-FLT PET/CT and USPIO MRI in a rat model
Rendon, DA, Kotedia, K, Afshar, SF, Punia, JN, Sabek, OM, Shirkey, BA, Zawaski, JA & Gaber, MW 2016, Journal of Nuclear Medicine, vol. 57, no. 2, pp. 266-271.

Osteocalcin effect on human ß-cells mass and function
Sabek, O, Nishimoto, SK, Fraga, D, Tejpal, N, Ricordi, C & Gaber, AO 2015, Endocrinology, vol. 156, no. 9, pp. 3137-3146.

Effects of glioma presence during radiotherapy on tissue damage
Zawaski, JA, Sabek, O, Wong, K & Gaber, MW 2015, Cancer Research, vol. 75, no. 15, 3321.

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