Nourhan Abdelfattah

Nourhan Abdelfattah, PhD

Instructor in Neurology, Academic Institute
Houston Methodist


Publications

Targeting aberrant replication and DNA repair events for treating breast cancers
Rajamanickam, S, Park, JH, Subbarayalu, P, Timilsina, S, Bates, K, Yadav, P, Nirzhor, SSR, Eedunuri, V, Mohammad, TA, Jung, KH, Onyeagucha, B, Abdelfattah, N, Benevides, R, Lee, G, Chen, Y, Vadlamudi, R, Brenner, A, Kaklamani, V, Jatoi, I, Kuhn, J, Hromas, R, Gupta, YK, Kaipparettu, BA, Arbiser, JL & Rao, MK 2022, , Communications Biology, vol. 5, no. 1, 493. https://doi.org/10.1038/s42003-022-03413-w

The antidepressant imipramine inhibits breast cancer growth by targeting estrogen receptor signaling and DNA repair events
Timilsina, S, Rajamanickam, S, Rao, A, Subbarayalu, P, Nirzhor, S, Abdelfattah, N, Viswanadhapalli, S, Chen, Y, Jatoi, I, Brenner, A, Rao, MK, Vadlamudi, R & Kaklamani, V 2022, , Cancer Letters, vol. 540, 215717. https://doi.org/10.1016/j.canlet.2022.215717

Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors
George, J, Chen, Y, Abdelfattah, N, Yamamoto, K, Gallup, TD, Adamson, SI, Rybinski, B, Srivastava, A, Kumar, P, Lee, MG, Baskin, DS, Jiang, W, Choi, JM, Flavahan, W, Chuang, JH, Kim, BYS, Xu, J, Jung, SY & Yun, K 2022, , Cancer research communications, vol. 2, no. 6, pp. 402-416. https://doi.org/10.1158/2767-9764.CRC-22-0124

M6A RNA Methylation Regulates Histone Ubiquitination to Support Cancer Growth and Progression
Yadav, P, Subbarayalu, P, Medina, D, Nirzhor, S, Timilsina, S, Rajamanickam, S, Eedunuri, VK, Gupta, Y, Zheng, S, Abdelfattah, N, Huang, Y, Vadlamudi, R, Hromas, R, Meltzer, P, Houghton, P, Chen, Y & Rao, MK 2022, , Cancer research, vol. 82, no. 10, pp. 1872-1889. https://doi.org/10.1158/0008-5472.CAN-21-2106

MiR-584-5p potentiates vincristine and radiation response by inducing spindle defects and DNA damage in medulloblastoma
Abdelfattah, N, Rajamanickam, S, Panneerdoss, S, Timilsina, S, Yadav, P, Onyeagucha, BC, Garcia, M, Vadlamudi, R, Chen, Y, Brenner, A, Houghton, P & Rao, MK 2018, , Nature Communications, vol. 9, no. 1, 4541. https://doi.org/10.1038/s41467-018-06808-8

Cross-talk among writers, readers, and erasers of m6A regulates cancer growth and progression
Panneerdoss, S, Eedunuri, VK, Yadav, P, Timilsina, S, Rajamanickam, S, Viswanadhapalli, S, Abdelfattah, N, Onyeagucha, BC, Cui, X, Lai, Z, Mohammad, TA, Gupta, YK, Huang, THM, Huang, Y, Chen, Y & Rao, MK 2018, , Science Advances, vol. 4, no. 10, eaar8263. https://doi.org/10.1126/sciadv.aar8263

Cross-talk between miR-471-5p and autophagy component proteins regulates LC3-associated phagocytosis (LAP) of apoptotic germ cells
Panneerdoss, S, Viswanadhapalli, S, Abdelfattah, N, Onyeagucha, BC, Timilsina, S, Mohammad, TA, Chen, Y, Drake, M, Vuori, K, Kumar, TR & Rao, MK 2017, , Nature Communications, vol. 8, no. 1, 598. https://doi.org/10.1038/s41467-017-00590-9

Novel post-transcriptional and post-translational regulation of pro-apoptotic protein BOK and anti-apoptotic protein Mcl-1 determine the fate of breast cancer cells to survive or die
Onyeagucha, B, Subbarayalu, P, Abdelfattah, N, Rajamanickam, S, Timilsina, S, Guzman, R, Zeballos, C, Eedunuri, V, Bansal, S, Mohammad, T, Chen, Y, Vadlamudi, RK & Rao, MK 2017, , Oncotarget, vol. 8, no. 49, pp. 85984-85996. https://doi.org/10.18632/oncotarget.20841