Mouaz Al-Mallah, MD

Beverly B. and Daniel C. Arnold Distinguished Chair, Department of Cardiology
Professor of Cardiology, Academic Institute
Full Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Biography

Dr. Mouaz Al-Mallah received his medical degree from the American University of Beirut, Lebanon.  He completed his training at Henry Ford Hospital, Wayne State University, Brigham and Women’s Hospital-Harvard Medical School, and the University of Michigan, Ann Arbor.  He is the director of cardiovascular PET at the Houston Methodist DeBakey Heart and Vascular Center and the Associate Director of Nuclear Cardiology. He is also the treasurer of the American Society of Nuclear Cardiology (ASNC).

Dr. Al-Mallah recently started the cardiac PET service at Houston Methodist DeBakey Heart and Vascular Center.  This service utilizes the most recent digital PET and performs multiple PET procedures including PET for myocardial perfusion imaging, viability, assessment of inflammatory cardiomyopathy, detection of cardiac infections and cardiac devices related infections as well as vascular graft infections.

He is a member of several American and European cardiovascular councils, while serving as an Associate Editor of Atherosclerosis and Cochrane reviews.  He is also a member of the Editorial Boards of Journal of the American College of Cardiology, and European Heart Journal -Cardiovascular Imaging.

Dr Al-Mallah received many local and international awards including Francis N. Fernandez Fellowship Award, King Abdullah International Medical Research Center award in 2011, Best Teacher award from Henry Ford Hospital, Elite Reviewer for the year 2013 for the Journal of the American College of Cardiology Journals, King Abdullah International Medical Research Center senior researcher award in 2016 and in 2019 was recipient of Best Teacher award from Houston Methodist DeBakey Heart and Vascular Center.  Many of his trainees have established academic careers and received multiple research awards while working under his supervision.

Description of Research

Dr. Al-Mallah’s research is focused on the prognostic value of advanced cardiac imaging procedures and its impact on risk prediction, patient management and outcomes.  He published on the prognostic value of cardiac CT, cardiac PET and nuclear cardiology as well as coronary calcium score. Dr. Al-Mallah has more than 300 published publications and book chapters and received multiple grants from various funding agencies.

Publications

The role of cardiac PET in diagnosis and prognosis of patients with ischemia with no obstructive coronary arteries (INOCA)
Al-Mallah, MH, Nayfeh, M & Alrifai, M 2024, , American Heart Journal Plus: Cardiology Research and Practice, vol. 43, 100399. https://doi.org/10.1016/j.ahjo.2024.100399

Prediction of the development of new coronary atherosclerotic plaques with radiomics
Lee, SE, Hong, Y, Hong, J, Jung, J, Sung, JM, Andreini, D, Al-Mallah, MH, Budoff, MJ, Cademartiri, F, Chinnaiyan, K, Choi, JH, Chun, EJ, Conte, E, Gottlieb, I, Hadamitzky, M, Kim, YJ, Lee, BK, Leipsic, JA, Maffei, E, Marques, H, Gonçalves, PDA, Pontone, G, Shin, S, Stone, PH, Samady, H, Virmani, R, Narula, J, Shaw, LJ, Bax, JJ, Lin, FY, Min, JK & Chang, HJ 2024, , Journal of cardiovascular computed tomography, vol. 18, no. 3, pp. 274-280. https://doi.org/10.1016/j.jcct.2024.02.003

FIT calculator: a multi-risk prediction framework for medical outcomes using cardiorespiratory fitness data
Elshawi, R, Sakr, S, Al-Mallah, MH, Keteyian, SJ, Brawner, CA & Ehrman, JK 2024, , Scientific Reports, vol. 14, no. 1, 8745. https://doi.org/10.1038/s41598-024-59401-z

Prognostic Interplay Between Exercise Capacity and PET-Derived Myocardial Flow Reserve: FIT-PET Study
Ahmed, AI, Al Rifai, M, Alahdab, F, Alfawara, MS, Han, Y, Nayfeh, M, Mahmarian, JJ, Nabi, F, Soliman, A, Patel, K, Zoghbi, WA & Al-Mallah, MH 2024, , JACC: Cardiovascular Imaging, vol. 17, no. 4, pp. 460-462. https://doi.org/10.1016/j.jcmg.2023.11.002

Epidemiology and Prognostic Implications of Coronary Artery Calcium in Asymptomatic Individuals With Prediabetes: A Multicohort Study
Rifai, MA, Al-Mallah, MH, Blaha, MJ, Patel, J, McEvoy, JW, Nasir, K, Shahid, I, Patel, KV, Sharma, G, Marrugat, J, Tizon-Marcos, H, Erbel, R, Stang, A, Jöckel, KH, Lehmann, N, Schramm, S, Schmidt, B, Blumenthal, RS, Virani, SS, Nambi, V & Cainzos-Achirica, M 2024, , Diabetes care, vol. 47, no. 4, pp. 698-706. https://doi.org/10.2337/dc23-1864

Ejection fraction and ventricular volumes on rubidium positron emission tomography: Validation against cardiovascular magnetic resonance
Han, Y, Ahmed, AI, Saad, JM, Alahdab, F, Al Rifai, MS, Murthy, VL & Al-Mallah, MH 2024, , Journal of Nuclear Cardiology, vol. 32, 101810, pp. 101810. https://doi.org/10.1016/j.nuclcard.2024.101810

Enhancing precision in test choice: Time for a personalized approach
Al-Mallah, MH & Al Rifai, M 2024, , Journal of Nuclear Cardiology, vol. 32, 101792, pp. 101792. https://doi.org/10.1016/j.nuclcard.2023.101792

Best Practices in Nuclear Imaging for the Diagnosis of Transthyretin Amyloid Cardiomyopathy (ATTR-CM) in KSA: The Eagle Eyes of Local Experts
Alqarni, A, Aljizeeri, A, Bakhsh, AM, El-Zeftawy, HAM, Farghaly, HR, Alqadhi, MAM, Algarni, M, Asiri, ZM, Osman, A, Haddadin, H, Alayary, I & Al-Mallah, MH 2024, , Diagnostics, vol. 14, no. 2, 212. https://doi.org/10.3390/diagnostics14020212

Reassessing the Role of Ischemia Imaging: Insights from the ISCHEMIA Trial
Nayfeh, M & Al-Mallah, MH 2024, , Nuclear Medicine and Molecular Imaging. https://doi.org/10.1007/s13139-023-00834-1

Air pollution and acute coronary syndrome: The air we breathe
Khan, SU & Al-Mallah, MH 2024, , Atherosclerosis, vol. 390, 117453, pp. 117453. https://doi.org/10.1016/j.atherosclerosis.2024.117453

Challenges and strategies to enable access to cardiac positron emission tomography in different parts of the world: The North American perspective
Sanghani, R, Al-Mallah, MH & Thompson, R 2024, , Journal of Nuclear Cardiology, vol. 31, 101790, pp. 101790. https://doi.org/10.1016/j.nuclcard.2023.101790

Left Upper Extremity Pain, Right Coronary Artery Culprit: A Puzzling Path to Aneurysm Discovery
Alfawara, MS, Modi, V, Chao, MF, Nayfeh, M, Alahdab, F, Alrifai, M & Al-Mallah, M 2024, , Methodist DeBakey cardiovascular journal, vol. 20, no. 1, pp. 14-17. https://doi.org/10.14797/mdcvj.1287

Development and Validation of a Quantitative Coronary CT Angiography Model for Diagnosis of Vessel-Specific Coronary Ischemia
CREDENCE and PACIFIC-1 Investigators 2024, , JACC: Cardiovascular Imaging. https://doi.org/10.1016/j.jcmg.2024.01.007

Simplified Approach to Predicting Obstructive Coronary Disease With Integration of Coronary Calcium: Development and External Validation
Miller, RJH, Gransar, H, Rozanski, A, Dey, D, Al-Mallah, M, Chow, BJW, Kaufmann, PA, Cademartiri, F, Maffei, E, Han, D, Slomka, PJ & Berman, DS 2023, , Journal of the American Heart Association, vol. 12, no. 24, e031601. https://doi.org/10.1161/JAHA.123.031601

Prognostic Interplay Between Exercise Capacity and PET-Derived Myocardial Flow Reserve: FIT-PET Study
Ahmed, AI, Al Rifai, M, Alahdab, F, Alfawara, MS, Han, Y, Nayfeh, M, Mahmarian, JJ, Nabi, F, Soliman, A, Patel, K, Zoghbi, WA & Al-Mallah, MH 2024, , JACC. Cardiovascular imaging, vol. 17, no. 4, pp. 460-462. https://doi.org/10.1016/j.jcmg.2023.11.002

Corrigendum to ‘Relation of Gender to Atherosclerotic Plaque Characteristics by Differing Angiographic Stenosis Severity’ The American Journal of Cardiology, Volume 204, 1 October 2023, Pages 276-283 (The American Journal of Cardiology (2023) 204 (276–283), (S0002914923005325), (10.1016/j.amjcard.2023.07.004))
Jonas, R, Patel, T, Crabtree, TR, Jennings, RS, Heo, R, Park, HB, Marques, H, Chang, HJ, Stuijfzand, WJ, Rosendael, ARV, Choi, JH, Doh, JH, Her, AY, Koo, BK, Nam, CW, Shin, SH, Cole, J, Gimelli, A, Khan, MA, Lu, B, Gao, Y, Nabi, F, Al-Mallah, MH, Nakazato, R, Schoepf, UJ, Driessen, RS, Bom, MJ, Thompson, RC, Jang, JJ, Ridner, M, Rowan, C, Avelar, E, Généreux, P, Knaapen, P, de Waard, GA, Pontone, G, Andreini, D, Bax, JJ, Choi, AD, Earls, JP, Hoffmann, U, Min, JK & Villines, TC 2023, , American Journal of Cardiology, vol. 207, pp. 523. https://doi.org/10.1016/j.amjcard.2023.10.010

Prognostic value of global myocardial flow reserve in patients with history of coronary artery bypass grafting
Al Rifai, M, Ahmed, AI, Saad, JM, Alahdab, F, Nabi, F & Al-Mallah, MH 2023, , European Heart Journal Cardiovascular Imaging, vol. 24, no. 11, pp. 1470-1477. https://doi.org/10.1093/ehjci/jead120

Coronary microvascular health in symptomatic patients with prior COVID-19 infection: an updated analysis
Ahmed, AI, Al Rifai, M, Alahdab, F, Saad, JM, Han, Y, Alfawara, MS, Nayfeh, M, Malahfji, M, Nabi, F, Mahmarian, JJ, Cooke, JP, Zoghbi, WA & Al-Mallah, MH 2023, , European Heart Journal Cardiovascular Imaging, vol. 24, no. 11, pp. 1544-1554. https://doi.org/10.1093/ehjci/jead118

Deep neural network for identification of impaired microvascular and vasomotor function from stress electrocardiography
Moody, JB, Poitrasson-Rivière, A, Renaud, JM, Hagio, T, Alahdab, F, Al-Mallah, MH, Vanderver, MD, Ficaro, EP & Murthy, VL 2023, , medRxiv. https://doi.org/10.1101/2023.10.25.23297552

Prognostic value of positron emission tomography derived myocardial flow reserve: A systematic review and meta-analysis
Ahmed, AI, Saad, JM, Alahdab, F, Han, Y, Nayfeh, M, Alfawara, MS, Al-Rifai, M & Al-mallah, M 2023, , Atherosclerosis, vol. 382, 117280, pp. 117280. https://doi.org/10.1016/j.atherosclerosis.2023.117280