Mouaz Al-Mallah, MD

Beverly B. and Daniel C. Arnold Distinguished Chair, Department of Cardiology
Professor of Cardiology, Academic Institute
Full Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Biography

Dr. Mouaz Al-Mallah received his medical degree from the American University of Beirut, Lebanon.  He completed his training at Henry Ford Hospital, Wayne State University, Brigham and Women’s Hospital-Harvard Medical School, and the University of Michigan, Ann Arbor.  He is the director of cardiovascular PET at the Houston Methodist DeBakey Heart and Vascular Center and the Associate Director of Nuclear Cardiology. He is also the treasurer of the American Society of Nuclear Cardiology (ASNC).

Dr. Al-Mallah recently started the cardiac PET service at Houston Methodist DeBakey Heart and Vascular Center.  This service utilizes the most recent digital PET and performs multiple PET procedures including PET for myocardial perfusion imaging, viability, assessment of inflammatory cardiomyopathy, detection of cardiac infections and cardiac devices related infections as well as vascular graft infections.

He is a member of several American and European cardiovascular councils, while serving as an Associate Editor of Atherosclerosis and Cochrane reviews.  He is also a member of the Editorial Boards of Journal of the American College of Cardiology, and European Heart Journal -Cardiovascular Imaging.

Dr Al-Mallah received many local and international awards including Francis N. Fernandez Fellowship Award, King Abdullah International Medical Research Center award in 2011, Best Teacher award from Henry Ford Hospital, Elite Reviewer for the year 2013 for the Journal of the American College of Cardiology Journals, King Abdullah International Medical Research Center senior researcher award in 2016 and in 2019 was recipient of Best Teacher award from Houston Methodist DeBakey Heart and Vascular Center.  Many of his trainees have established academic careers and received multiple research awards while working under his supervision.

Description of Research

Dr. Al-Mallah’s research is focused on the prognostic value of advanced cardiac imaging procedures and its impact on risk prediction, patient management and outcomes.  He published on the prognostic value of cardiac CT, cardiac PET and nuclear cardiology as well as coronary calcium score. Dr. Al-Mallah has more than 300 published publications and book chapters and received multiple grants from various funding agencies.

Publications

Sex differences in machine learning computed tomography-derived fractional flow reserve
Al Rifai, M, Ahmed, AI, Han, Y, Saad, JM, Alnabelsi, T, Nabi, F, Chang, SM, Cocker, M, Schwemmer, C, Ramirez-Giraldo, JC, Zoghbi, WA, Mahmarian, JJ & Al-Mallah, MH 2022, , Scientific Reports, vol. 12, no. 1, 13861. https://doi.org/10.1038/s41598-022-17875-9

Relation of Exercise Capacity to Incident Heart Failure Among Men and Women With Coronary Heart Disease (from the Henry Ford Exercise Testing [FIT] Project)
Gorgis, S, Ehrman, JK, Blaha, MJ, Qureshi, WT, Keteyian, SJ, Al-Mallah, MH & Brawner, CA 2022, , American Journal of Cardiology, vol. 181, pp. 66-70. https://doi.org/10.1016/j.amjcard.2022.07.016

SNMMI/ACR/ASNC/SCMR Joint Credentialing Statement for Cardiac PET/MRI: Endorsed by the American Heart Association
Ruddy, TD, Al-Mallah, M, Arrighi, JA, Bois, JP, Bluemke, DA, Di Carli, MF, Dilsizian, V, Gropler, RJ, Jadvar, H, Malhotra, S, Pelletier-Galarneau, M, Schindler, TH, Woodard, PK & Chareonthaitawee, P 2022, , Circulation: Cardiovascular Imaging, vol. 15, no. 8, pp. E014576. https://doi.org/10.1161/CIRCIMAGING.122.014576

The Impact of Revascularization on Mortality: A Debate on Patient Selection Bias vs Entry Bias
Al-Mallah, MH & Dilsizian, V 2022, , Journal of the American College of Cardiology, vol. 80, no. 3, pp. 216-218. https://doi.org/10.1016/j.jacc.2022.04.051

SNMMI/ACR/ASNC/SCMR joint credentialing statement for cardiac PET/MRI
Ruddy, TD, Al-Mallah, M, Arrighi, JA, Bois, JP, Bluemke, DA, Di Carli, MF, Dilsizian, V, Gropler, RJ, Jadvar, H, Malhotra, S, Pelletier-Galarneau, M, Schindler, TH, Woodard, PK & Chareonthaitawee, P 2022, , Journal of Cardiovascular Magnetic Resonance, vol. 24, no. 1, 43. https://doi.org/10.1186/s12968-022-00867-z

Incremental prognostic value of spect over CCTA
Javaid, A, Ahmed, AI, Han, Y, Al Rifai, M, Saad, JM, Alfawara, MS, Alahdab, F, El Nihum, L, Jimenez, Y, Newstorm, E & Al-Mallah, MH 2022, , International Journal of Cardiology, vol. 358, pp. 120-127. https://doi.org/10.1016/j.ijcard.2022.04.025

Prognostic Interplay Between Coronary Artery Calcium Scoring and Cardiorespiratory FItness: The CAC-FIT Study
Ahmed, AI, Saad, JM, Han, Y, Alfawara, MS, Soliman, A, Nabi, F, Zoghbi, WA & Al-Mallah, MH 2022, , Mayo Clinic Proceedings, vol. 97, no. 7, pp. 1269-1281. https://doi.org/10.1016/j.mayocp.2022.03.032

Evaluating coronary atherosclerosis progression among South Asians
Al Rifai, M, Ahmed, AI & Al-Mallah, MH 2022, , Atherosclerosis, vol. 353, pp. 30-32. https://doi.org/10.1016/j.atherosclerosis.2022.06.1016

Unbiased COVID-19 Pandemic With Biased Global Recovery
Al-Mallah, M & Naqvi, TZ 2022, , Journal of the American College of Cardiology, vol. 79, no. 20, pp. 2018-2020. https://doi.org/10.1016/j.jacc.2022.03.350

Inflammatory Cardiomyopathies: A Need to Identify Indolent Inflammation
Ali, HJR, Kassi, M, Agrawal, T, Shah, DJ, Alnabelsi, T, El-Tallawi, C, Al-Mallah, M & Bhimaraj, A 2022, , JACC: Case Reports, vol. 4, no. 10, pp. 632-638. https://doi.org/10.1016/j.jaccas.2022.03.020

The effect of scan and patient parameters on the diagnostic performance of AI for detecting coronary stenosis on coronary CT angiography
Jonas, RA, Barkovich, E, Choi, AD, Griffin, WF, Riess, J, Marques, H, Chang, HJ, Choi, JH, Doh, JH, Her, AY, Koo, BK, Nam, CW, Park, HB, Shin, SH, Cole, J, Gimelli, A, Khan, MA, Lu, B, Gao, Y, Nabi, F, Nakazato, R, Schoepf, UJ, Driessen, RS, Bom, MJ, Thompson, RC, Jang, JJ, Ridner, M, Rowan, C, Avelar, E, Généreux, P, Knaapen, P, de Waard, GA, Pontone, G, Andreini, D, Guglielmo, M, Al-Mallah, MH, Jennings, RS, Crabtree, TR & Earls, JP 2022, , Clinical Imaging, vol. 84, pp. 149-158. https://doi.org/10.1016/j.clinimag.2022.01.016

Interoperator reliability of an on-site machine learning-based prototype to estimate CT angiography-derived fractional flow reserve
Han, Y, Ahmed, AI, Schwemmer, C, Cocker, M, Alnabelsi, TS, Saad, JM, Giraldo, JCR & Al-Mallah, MH 2022, , Open Heart, vol. 9, no. 1, e001951. https://doi.org/10.1136/openhrt-2021-001951

Association of Plaque Location and Vessel Geometry Determined by Coronary Computed Tomographic Angiography with Future Acute Coronary Syndrome-Causing Culprit Lesions
Han, D, Lin, A, Kuronuma, K, Tzolos, E, Kwan, AC, Klein, E, Andreini, D, Bax, JJ, Cademartiri, F, Chinnaiyan, K, Chow, BJW, Conte, E, Cury, RC, Feuchtner, G, Hadamitzky, M, Kim, YJ, Leipsic, JA, Maffei, E, Marques, H, Plank, F, Pontone, G, Villines, TC, Al-Mallah, MH, De Araújo Gonçalves, P, Danad, I, Gransar, H, Lu, Y, Lee, JH, Lee, SE, Baskaran, L, AlAref, SJ, Yoon, YE, Van Rosendael, A, Budoff, MJ, Samady, H, Stone, PH, Virmani, R, Achenbach, S, Narula, J, Chang, HJ, Min, JK, Lin, FY, Shaw, LJ, Slomka, PJ, Dey, D & Berman, DS 2022, , JAMA Cardiology, vol. 7, no. 3, pp. 309-319. https://doi.org/10.1001/jamacardio.2021.5705

Current and Future Applications of Artificial Intelligence in Coronary Artery Disease
Gautam, N, Saluja, P, Malkawi, A, Rabbat, MG, Al-Mallah, MH, Pontone, G, Zhang, Y, Lee, BC & Al’Aref, SJ 2022, , Healthcare (Switzerland), vol. 10, no. 2, 232. https://doi.org/10.3390/healthcare10020232

Prognostic Value of Computed Tomography-Derived Fractional Flow Reserve Comparison With Myocardial Perfusion Imaging
Ahmed, AI, Han, Y, Al Rifai, M, Alnabelsi, T, Nabi, F, Chang, SM, Cocker, M, Schwemmer, C, Ramirez-Giraldo, JC, Kleiman, NS, Zoghbi, WA, Mahmarian, JJ & Al-Mallah, MH 2022, , JACC: Cardiovascular Imaging, vol. 15, no. 2, pp. 284-295. https://doi.org/10.1016/j.jcmg.2021.09.007

Angiotensin Converting Enzyme Inhibitors and Angiotensin Receptor Blockers and the Risk of SARS-CoV-2 Infection or Hospitalization with COVID-19 Disease: A Systematic Review and Meta-Analysis
Tleyjeh, IM, Bin Abdulhak, AA, Tlayjeh, H, Al-Mallah, MH, Sohail, MR, Hassett, LC, Siller-Matula, JM & Kashour, T 2022, , American journal of therapeutics, vol. 29, no. 1, pp. E74-E84. https://doi.org/10.1097/MJT.0000000000001319

Associations between dyspnoea, coronary atherosclerosis, and cardiovascular outcomes: results from the long-term follow-up CONFIRM registry
van Rosendael, AR, Bax, AM, van den Hoogen, IJ, Smit, JM, AlAref, SJ, Achenbach, S, Al-Mallah, MH, Andreini, D, Berman, DS, Budoff, MJ, Cademartiri, F, Callister, TQ, Chang, HJ, Chinnaiyan, K, Chow, BJW, Cury, RC, DeLago, A, Feuchtner, G, Hadamitzky, M, Hausleiter, J, Kaufmann, PA, Kim, YJ, Leipsic, JA, Maffei, E, Marques, H, de Araújo Gonçalves, P, Pontone, G, Raff, GL, Rubinshtein, R, Villines, TC, Gransar, H, Lu, Y, Peña, JM, Lin, FY, Shaw, LJ, Narula, J, Min, JK & Bax, JJ 2022, , European Heart Journal Cardiovascular Imaging, vol. 23, no. 2, pp. 266-274. https://doi.org/10.1093/ehjci/jeaa323

Association of Coronary Artery Calcium Density and Volume With Predicted Atherosclerotic Cardiovascular Disease Risk and Cardiometabolic Risk Factors in South Asians: The Mediators of Atherosclerosis in South Asians Living in America (MASALA) Study
Al Rifai, M, Kanaya, AM, Kandula, NR, Patel, J, Al-Mallah, MH, Budoff, M, Cainzos-Achirica, M, Criqui, MH & Virani, SS 2022, , Current Problems in Cardiology. https://doi.org/10.1016/j.cpcardiol.2022.101105

Added Prognostic Value of Plaque Burden to Computed Tomography Angiography and Myocardial Perfusion Imaging in Patients with Diabetes
Alnabelsi, T, Ahmed, AI, Han, Y, Al Rifai, M, Nabi, F, Cainzos-Achirica, M & Al-Mallah, MH 2022, , American Journal of Medicine, vol. 135, no. 6, pp. 761-768.e7. https://doi.org/10.1016/j.amjmed.2021.12.010

Cardiovascular magnetic resonance for suspected cardiac amyloidosis: where are we now?
Saad, JM, Ahmed, AI, Han, Y, Malahfji, M, Aljizeeri, A & Al-Mallah, MH 2022, , Heart Failure Reviews, vol. 27, no. 5, pp. 1543-1548. https://doi.org/10.1007/s10741-022-10226-w