Mouaz Al-Mallah, MD

Beverly B. and Daniel C. Arnold Distinguished Chair, Department of Cardiology
Professor of Cardiology, Academic Institute
Full Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Biography

Dr. Mouaz Al-Mallah received his medical degree from the American University of Beirut, Lebanon.  He completed his training at Henry Ford Hospital, Wayne State University, Brigham and Women’s Hospital-Harvard Medical School, and the University of Michigan, Ann Arbor.  He is the director of cardiovascular PET at the Houston Methodist DeBakey Heart and Vascular Center and the Associate Director of Nuclear Cardiology. He is also the treasurer of the American Society of Nuclear Cardiology (ASNC).

Dr. Al-Mallah recently started the cardiac PET service at Houston Methodist DeBakey Heart and Vascular Center.  This service utilizes the most recent digital PET and performs multiple PET procedures including PET for myocardial perfusion imaging, viability, assessment of inflammatory cardiomyopathy, detection of cardiac infections and cardiac devices related infections as well as vascular graft infections.

He is a member of several American and European cardiovascular councils, while serving as an Associate Editor of Atherosclerosis and Cochrane reviews.  He is also a member of the Editorial Boards of Journal of the American College of Cardiology, and European Heart Journal -Cardiovascular Imaging.

Dr Al-Mallah received many local and international awards including Francis N. Fernandez Fellowship Award, King Abdullah International Medical Research Center award in 2011, Best Teacher award from Henry Ford Hospital, Elite Reviewer for the year 2013 for the Journal of the American College of Cardiology Journals, King Abdullah International Medical Research Center senior researcher award in 2016 and in 2019 was recipient of Best Teacher award from Houston Methodist DeBakey Heart and Vascular Center.  Many of his trainees have established academic careers and received multiple research awards while working under his supervision.

Description of Research

Dr. Al-Mallah’s research is focused on the prognostic value of advanced cardiac imaging procedures and its impact on risk prediction, patient management and outcomes.  He published on the prognostic value of cardiac CT, cardiac PET and nuclear cardiology as well as coronary calcium score. Dr. Al-Mallah has more than 300 published publications and book chapters and received multiple grants from various funding agencies.

Publications

Coronary Artery Calcium and the Age-Specific Competing Risk of Cardiovascular Versus Cancer Mortality: The Coronary Artery Calcium Consortium
Whelton, SP, Rifai, MA, Marshall, CH, Dardari, Z, Shaw, LJ, Al-Mallah, MH, Rozanski, A, Mortensen, MB, Dzaye, O, Bazzano, L, Kelly, TN, Matsushita, K, Rumberger, JA, Berman, DS, Budoff, MJ, Miedema, MD, Nasir, K & Blaha, MJ 2020, , American Journal of Medicine, vol. 133, no. 10, pp. e575-e583. https://doi.org/10.1016/j.amjmed.2020.02.034

The Vulnerable Plaque: Recent Advances in Computed Tomography Imaging to Identify the Vulnerable Patient
Beg, F, Rehman, H & Al-Mallah, M 2020, , Current Atherosclerosis Reports, vol. 22, no. 10, 58. https://doi.org/10.1007/s11883-020-00879-z

Percent atheroma volume: Optimal variable to report whole-heart atherosclerotic plaque burden with coronary CTA, the PARADIGM study
van Rosendael, AR, Lin, FY, Ma, X, van den Hoogen, IJ, Gianni, U, Al Hussein, O, AlAref, SJ, Peña, JM, Andreini, D, Al-Mallah, MH, Budoff, MJ, Cademartiri, F, Chinnaiyan, K, Choi, JH, Conte, E, Marques, H, de Araújo Gonçalves, P, Gottlieb, I, Hadamitzky, M, Leipsic, JA, Maffei, E, Pontone, G, Raff, GL, Shin, S, Kim, YJ, Lee, BK, Chun, EJ, Sung, JM, Lee, SE, Berman, DS, Virmani, R, Samady, H, Stone, PH, Narula, J, Bax, JJ, Shaw, LJ, Min, JK & Chang, HJ 2020, , Journal of cardiovascular computed tomography, vol. 14, no. 5, pp. 400-406. https://doi.org/10.1016/j.jcct.2020.01.012

Non-obstructive high-risk plaques increase the risk of future culprit lesions comparable to obstructive plaques without high-risk features: the ICONIC study
Ferraro, RA, van Rosendael, AR, Lu, Y, Andreini, D, Al-Mallah, MH, Cademartiri, F, Chinnaiyan, K, Chow, BJW, Conte, E, Cury, RC, Feuchtner, G, de Araújo Gonçalves, P, Hadamitzky, M, Kim, YJ, Leipsic, J, Maffei, E, Marques, H, Plank, F, Pontone, G, Raff, GL, Villines, TC, Lee, SE, AlAref, SJ, Baskaran, L, Cho, I, Danad, I, Gransar, H, Budoff, MJ, Samady, H, Stone, PH, Virmani, R, Narula, J, Berman, DS, Chang, HJ, Bax, JJ, Min, JK, Shaw, LJ & Lin, FY 2020, , European Heart Journal Cardiovascular Imaging, vol. 21, no. 9, pp. 973-980. https://doi.org/10.1093/ehjci/jeaa048

Prognostic significance of subtle coronary calcification in patients with zero coronary artery calcium score: From the CONFIRM registry
Han, D, Klein, E, Friedman, J, Gransar, H, Achenbach, S, Al-Mallah, MH, Budoff, MJ, Cademartiri, F, Maffei, E, Callister, TQ, Chinnaiyan, K, Chow, BJW, DeLago, A, Hadamitzky, M, Hausleiter, J, Kaufmann, PA, Villines, TC, Kim, YJ, Leipsic, J, Feuchtner, G, Cury, RC, Pontone, G, Andreini, D, Marques, H, Rubinshtein, R, Chang, HJ, Lin, FY, Shaw, LJ, Min, JK & Berman, DS 2020, , Atherosclerosis, vol. 309, pp. 33-38. https://doi.org/10.1016/j.atherosclerosis.2020.07.011

Cardiac Imaging in the Post-ISCHEMIA Trial Era: A Multisociety Viewpoint
Shaw, L, Kwong, RY, Nagel, E, Salerno, M, Jaffer, F, Blankstein, R, Dilsizian, V, Flachskampf, F, Grayburn, P, Leipsic, J, Marwick, T, Nieman, K, Raman, S, Sengupta, P, Zoghbi, W, Pellikka, PA, Swaminathan, M, Dorbala, S, Thompson, R, Al-Mallah, M, Calnon, D, Polk, D, Soman, P, Beanlands, R, Garrett, KN, Henry, TD, Rao, SV, Duffy, PL, Cox, D, Grines, C, Mahmud, E, Bucciarelli-Ducci, C, Plein, S, Greenwood, JP, Berry, C, Carr, J, Arai, AE, Murthy, VL, Ruddy, TD & Chandrashekhar, Y 2020, , JACC: Cardiovascular Imaging, vol. 13, no. 8, pp. 1815-1833. https://doi.org/10.1016/j.jcmg.2020.05.001

Myocardial Perfusion Imaging Using Positron Emission Tomography
El-Tallawi, KC, Aljizeeri, A, Nabi, F & Al-Mallah, M 2020, , Methodist DeBakey cardiovascular journal, vol. 16, no. 2, pp. 114-121. https://doi.org/10.14797/mdcj-16-2-114

No pleotropic effects of linagliptin on atherosclerotic plaques: Case closed
Al-Mallah, MH, Hyafil, F & Santulli, G 2020, , Atherosclerosis, vol. 305, pp. 61-63. https://doi.org/10.1016/j.atherosclerosis.2020.05.009

The relationship between cardiorespiratory fitness, cardiovascular risk factors and atherosclerosis
Chu, DJ, Al Rifai, M, Virani, SS, Brawner, CA, Nasir, K & Al-Mallah, M 2020, Atherosclerosis, vol. 304, pp. 44-52. https://doi.org/10.1016/j.atherosclerosis.2020.04.019

Cardiorespiratory Fitness and Incident Stroke Types: The FIT (Henry Ford ExercIse Testing) Project
Al Rifai, M, Blaha, MJ, Ahmed, A, Almasoudi, F, Johansen, MC, Qureshi, W, Sakr, S, Virani, SS, Brawner, CA, Ehrman, JK, Keteyian, SJ & Al-Mallah, M 2020, Mayo Clinic Proceedings, vol. 95, no. 7, pp. 1379-1389. https://doi.org/10.1016/j.mayocp.2019.11.027

Guidance and best practices for nuclear cardiology laboratories during the coronavirus disease 2019 (COVID-19) pandemic: An Information Statement from ASNC and SNMMI
Skali, H, Murthy, VL, Al-Mallah, MH, Bateman, TM, Beanlands, R, Better, N, Calnon, DA, Dilsizian, V, Gimelli, A, Pagnanelli, R, Polk, DM, Soman, P, Thompson, RC, Einstein, AJ & Dorbala, S 2020, , Journal of Nuclear Cardiology, vol. 27, no. 3, pp. 1022-1029. https://doi.org/10.1007/s12350-020-02123-2

The role of cardiac imaging in the management of non-ischemic cardiovascular diseases in human immunodeficiency virus infection
Aljizeeri, A, Small, G, Malhotra, S, Buechel, R, Jain, D, Dwivedi, G & Al-Mallah, MH 2020, , Journal of Nuclear Cardiology, vol. 27, no. 3, pp. 801-818. https://doi.org/10.1007/s12350-019-01676-1

Differences in Progression to Obstructive Lesions per High-Risk Plaque Features and Plaque Volumes With CCTA
Lee, SE, Sung, JM, Andreini, D, Al-Mallah, MH, Budoff, MJ, Cademartiri, F, Chinnaiyan, K, Choi, JH, Chun, EJ, Conte, E, Gottlieb, I, Hadamitzky, M, Kim, YJ, Lee, BK, Leipsic, JA, Maffei, E, Marques, H, de Araújo Gonçalves, P, Pontone, G, Raff, GL, Shin, S, Stone, PH, Samady, H, Virmani, R, Narula, J, Berman, DS, Shaw, LJ, Bax, JJ, Lin, FY, Min, JK & Chang, HJ 2020, , JACC: Cardiovascular Imaging, vol. 13, no. 6, pp. 1409-1417. https://doi.org/10.1016/j.jcmg.2019.09.011

T 1 mapping performance and measurement repeatability: Results from the multi-national T 1 mapping standardization phantom program (T1MES)
Captur, G, Bhandari, A, Brühl, R, Ittermann, B, Keenan, KE, Yang, Y, Eames, RJ, Benedetti, G, Torlasco, C, Ricketts, L, Boubertakh, R, Fatih, N, Greenwood, JP, Paulis, LEM, Lawton, CB, Bucciarelli-Ducci, C, Lamb, HJ, Steeds, R, Leung, SW, Berry, C, Valentin, S, Flett, A, De Lange, C, Decobelli, F, Viallon, M, Croisille, P, Higgins, DM, Greiser, A, Pang, W, Hamilton-Craig, C, Strugnell, WE, Dresselaers, T, Barison, A, Dawson, D, Taylor, AJ, Mongeon, FP, Plein, S, Messroghli, D, Al-Mallah, M, Grieve, SM, Lombardi, M, Jang, J, Salerno, M, Chaturvedi, N, Kellman, P, Bluemke, DA, Nezafat, R, Gatehouse, P & Moon, JC 2020, Journal of Cardiovascular Magnetic Resonance, vol. 22, no. 1, 31. https://doi.org/10.1186/s12968-020-00613-3

Facility-level variation in cardiac stress test use among patients with diabetes: Findings from the Veterans Affairs National Database
Mahtta, D, Ahmed, ST, Shah, NR, Ramsey, DJ, Akeroyd, JM, Nasir, K, Hamzeh, IR, Elgendy, IY, Waldo, SW, Al-Mallah, M, Jneid, H, Ballantyne, CM, Petersen, LA & Virani, SS 2020, Diabetes care, vol. 43, no. 5, pp. E58-E60. https://doi.org/10.2337/dc19-2160

Coronary atherosclerosis scoring with semiquantitative CCTA risk scores for prediction of major adverse cardiac events: Propensity score-based analysis of diabetic and non-diabetic patients
van den Hoogen, IJ, van Rosendael, AR, Lin, FY, Lu, Y, Dimitriu-Leen, AC, Smit, JM, Scholte, AJHA, Achenbach, S, Al-Mallah, MH, Andreini, D, Berman, DS, Budoff, MJ, Cademartiri, F, Callister, TQ, Chang, HJ, Chinnaiyan, K, Chow, BJW, Cury, RC, DeLago, A, Feuchtner, G, Hadamitzky, M, Hausleiter, J, Kaufmann, PA, Kim, YJ, Leipsic, JA, Maffei, E, Marques, H, de Araújo Gonçalves, P, Pontone, G, Raff, GL, Rubinshtein, R, Villines, TC, Gransar, H, Jones, EC, Peña, JM, Shaw, LJ, Min, JK & Bax, JJ 2020, , Journal of cardiovascular computed tomography, vol. 14, no. 3, pp. 251-257. https://doi.org/10.1016/j.jcct.2019.11.015

Clinical risk factors and atherosclerotic plaque extent to define risk for major events in patients without obstructive coronary artery disease: The long-term coronary computed tomography angiography CONFIRM registry
Van Rosendael, AR, Bax, AM, Smit, JM, Van Den Hoogen, IJ, Ma, X, AlAref, S, Achenbach, S, Al-Mallah, MH, Andreini, D, Berman, DS, Budoff, MJ, Cademartiri, F, Callister, TQ, Chang, HJ, Chinnaiyan, K, Chow, BJW, Cury, RC, Delago, A, Feuchtner, G, Hadamitzky, M, Hausleiter, J, Kaufmann, PA, Kim, YJ, Leipsic, JA, Maffei, E, Marques, H, De Araújo Gonçalves, P, Pontone, G, Raff, GL, Rubinshtein, R, Villines, TC, Gransar, H, Lu, Y, Peña, JM, Lin, FY, Shaw, LJ, Min, JK & Bax, JJ 2020, , European Heart Journal Cardiovascular Imaging, vol. 21, no. 5, pp. 479-488. https://doi.org/10.1093/ehjci/jez322

Interplay of Coronary Artery Calcium and Risk Factors for Predicting CVD/CHD Mortality: The CAC Consortium
Grandhi, GR, Mirbolouk, M, Dardari, ZA, Al-Mallah, MH, Rumberger, JA, Shaw, LJ, Blankstein, R, Miedema, MD, Berman, DS, Budoff, MJ, Krumholz, HM, Blaha, MJ & Nasir, K 2020, , JACC: Cardiovascular Imaging, vol. 13, no. 5, pp. 1175-1186. https://doi.org/10.1016/j.jcmg.2019.08.024

Coronary Artery Calcium as a Synergistic Tool for the Age- and Sex-Specific Risk of Cardiovascular and Cancer Mortality: The Coronary Artery Calcium Consortium
Dzaye, O, Al Rifai, M, Dardari, Z, Shaw, LJ, Al-Mallah, MH, Handy Marshall, C, Rozanski, A, Mortensen, MB, Duebgen, M, Matsushita, K, Rumberger, JA, Berman, DS, Budoff, MJ, Miedema, MD, Nasir, K, Blaha, MJ & Whelton, SP 2020, , Journal of the American Heart Association, vol. 9, no. 8, pp. e015306. https://doi.org/10.1161/JAHA.119.015306

Multimodality imaging: Bird’s eye view from the 2019 American College of Cardiology Scientific Sessions
Phillips, LM, Winchester, D, Saric, M, Lloyd, SG, Blankstein, R & Al-Mallah, M 2020, Journal of Nuclear Cardiology, vol. 27, no. 2, pp. 410-416. https://doi.org/10.1007/s12350-019-02016-z