Moonsoo M. Jin

Moonsoo M. Jin, PhD

MD Anderson Foundation Chair in Biomedical Imaging, Department of Radiology
Professor of Biomedical Engineering in Radiology, Academic Institute
Full Member, Research Institute
Vice Chair of Research, Department of Radiology
Director, Translation Imaging Center PET Core, Department of Radiology
Houston Methodist
Weill Cornell Medical College


mjin@houstonmethodist.org
Publications

Low-dose targeted radionuclide therapy synergizes with CAR T cells and enhances tumor response
Yang, Y, Vedvyas, Y, Alcaina, Y, Son, JY, Min, IM & Jin, MM 2024, , Frontiers in immunology, vol. 15, 1355388, pp. 1355388. https://doi.org/10.3389/fimmu.2024.1355388

Chimeric Antigen Receptor T Cell Therapy Targeting Epithelial Cell Adhesion Molecule in Gastric Cancer: Mechanisms of Tumor Resistance
Yang, Y, Louie, R, Puc, J, Vedvyas, Y, Alcaina, Y, Min, IM, Britz, M, Luciani, F & Jin, MM 2023, , Cancers, vol. 15, no. 23, 5552. https://doi.org/10.3390/cancers15235552

Activation of the JAK/STAT Pathway Leads to BRAF Inhibitor Resistance in BRAFV600E Positive Thyroid Carcinoma
Limberg, J, Egan, CE, Gray, KD, Singh, M, Loewenstein, Z, Yang, Y, Riascos, MC, Asadi, HA, Safe, P, Eshaky, SE, Liang, H, Ullmann, TM, Wang, W, Li, W, Zhang, T, Xiang, J, Stefanova, D, Jin, MM, Zarnegar, R, Fahey, TJ & Min, IM 2023, , Molecular Cancer Research, vol. 21, no. 5, pp. 397-410. https://doi.org/10.1158/1541-7786.MCR-21-0832

Inducible expression of interleukin-12 augments the efficacy of affinity-tuned chimeric antigen receptors in murine solid tumor models
Yang, Y, Yang, H, Alcaina, Y, Puc, J, Birt, A, Vedvyas, Y, Gallagher, M, Alla, S, Riascos, MC, McCloskey, JE, Du, K, Gonzalez-Valdivieso, J, Min, I, de Stanchina, E, Britz, M, von Hofe, E & Jin, MM 2023, , Nature Communications, vol. 14, no. 1, 2068, pp. 2068. https://doi.org/10.1038/s41467-023-37646-y, https://doi.org/10.1038/s41467-023-37646-y

Targeted delivery of low-dose radiation alleviates tumor resistance to CAR-T cell therapy
Yang, Y, Alcaina, Y, Vedvyas, Y, Riascos, MC, Fung, EK, Vaughn, B, Cheal, SM, Min, IM, Vanpouille-Box, C & Jin, MM 2023, . in Cancer Research. vol. 83 (7_Supplement): 5084, AACR Annual Meeting 2023, Orlando, United States, 4/14/23. <https://aacrjournals.org/cancerres/article/83/7_Supplement/5084/724191/Abstract-5084-Targeted-delivery-of-low-dose?searchresult=1>

Single cell analysis reveals tumor evolution and CAR T cell dysfunction associated with tumor resistance
Yang, Y, Louie, R, Puc, J, Vedvyas, Y, Alcaina, Y, Min, IM, Britz, M, Luciani, F & Jin, MM 2023, . in Cancer Research. vol. 83(7_Suppl): 912. AACR Annual Meeting 2023, Orlando, United States, 4/14/23. <https://aacrjournals.org/cancerres/article/83/7_Supplement/912/719908/Abstract-912-Single-cell-analysis-reveals-tumor>

Target selection and clinical chimeric antigen receptor T cell activity against solid tumors
von Hofe, E, Yang, Y & Jin, MM 2023, , iLABMED, vol. 1, no. 1, pp. 29-43. https://doi.org/10.1002/ila2.8

SSTR2 as an anatomical imaging marker and a safety switch to monitor and manage CAR T cell toxicity
Alcaina, Y, Yang, Y, Vedvyas, Y, McCloskey, JE & Jin, MM 2022, , Scientific Reports, vol. 12, no. 1, 20932. https://doi.org/10.1038/s41598-022-25224-z, https://doi.org/10.1038/s41598-022-25224-z

Optimized production of a bioactive human recombinant protein from the microalgae Chlamydomonas reinhardtii grown at high density in a fed-batch bioreactor
Torres-Tiji, Y, Fields, FJ, Yang, Y, Heredia, V, Horn, SJ, Keremane, SR, Jin, MM & Mayfield, SP 2022, , Algal Research, vol. 66, 102786. https://doi.org/10.1016/j.algal.2022.102786

SSTR2 as an anatomical imaging marker and a safety switch to monitor and manage CAR T cell toxicity
Alcaina, Y, Yang, Y, Vedvyas, Y, McCloskey, JE & Jin, MM 2022, , Scientific Reports, vol. 12, no. 1. https://doi.org/10.1038/s41598-022-25224-z

Optimized production of a bioactive human recombinant protein from the microalgae Chlamydomonas reinhardtii grown at high density in a fed-batch bioreactor
Torres-Tiji, Y, Fields, FJ, Yang, Y, Heredia, V, Horn, SJ, Keremane, SR, Jin, MM & Mayfield, SP 2022, , Algal Research, vol. 66. https://doi.org/10.1016/j.algal.2022.102786

Yeast Surface Display forIn VitroBiosynthetic Pathway Reconstruction
Luo, B, Jin, MM, Li, X, Makunga, NP & Hu, X 2021, , ACS Synthetic Biology, vol. 10, no. 11, pp. 2938-2946. https://doi.org/10.1021/acssynbio.1c00175

Bispecific CAR T Cells against EpCAM and Inducible ICAM-1 Overcome Antigen Heterogeneity and Generate Superior Antitumor Responses
Yang, Y, McCloskey, JE, Yang, H, Puc, J, Alcaina, Y, Vedvyas, Y, Gomez Gallegos, AA, Ortiz-Sánchez, E, de Stanchina, E, Min, IM, von Hofe, E & Jin, MM 2021, , Cancer immunology research, vol. 9, no. 10, pp. 1158-1174. https://doi.org/10.1158/2326-6066.CIR-21-0062

Bispecific CAR T Cells against EpCAM and Inducible ICAM-1 Overcome Antigen Heterogeneity and Generate Superior Antitumor Responses
Yang, Y, McCloskey, JE, Yang, H, Puc, J, Alcaina, Y, Vedvyas, Y, Gomez Gallegos, AA, Ortiz-Sánchez, E, de Stanchina, E, Min, IM, von Hofe, E & Jin, MM 2021, , Cancer immunology research, vol. 9, no. 10, pp. 1158-1174. https://doi.org/10.1158/2326-6066.CIR-21-0062, https://doi.org/10.1158/2326-6066.CIR-21-0062

CSPG4 Is a Potential Therapeutic Target in Anaplastic Thyroid Cancer
Egan, CE, Stefanova, D, Ahmed, A, Raja, VJ, Thiesmeyer, JW, Chen, KJ, Greenberg, JA, Zhang, T, He, B, Finnerty, BM, Zarnegar, R, Jin, MM, Scognamiglio, T, Dephoure, N, Fahey, T & Min, IM 2021, , Thyroid, vol. 31, no. 10, pp. 1481-1493. https://doi.org/10.1089/thy.2021.0067

Creation of an Anti-Inflammatory, Leptin-Dependent Anti-Obesity Celastrol Mimic with Better Druggability
Zhou, B, Yuan, Y, Shi, L, Hu, S, Wang, D, Yang, Y, Pan, Y, Kong, D, Shikov, AN, Duez, P, Jin, M, Li, X & Hu, X 2021, , Frontiers in Pharmacology, vol. 12, 705252. https://doi.org/10.3389/fphar.2021.705252

Validation of MRI quantitative susceptibility mapping of superparamagnetic iron oxide nanoparticles for hyperthermia applications in live subjects
Deh, K, Zaman, M, Vedvyas, Y, Liu, Z, Gillen, KMC, O’ Malley, P, Bedretdinova, D, Nguyen, T, Lee, R, Spincemaille, P, Kim, J, Wang, Y & Jin, MM 2020, , Scientific Reports, vol. 10, no. 1, 1171. https://doi.org/10.1038/s41598-020-58219-9

Publisher Correction: Manufacturing and preclinical validation of CAR T cells targeting ICAM-1 for advanced thyroid cancer therapy (Scientific Reports, (2019), 9, 1, (10634), 10.1038/s41598-019-46938-7)
Vedvyas, Y, McCloskey, JE, Yang, Y, Min, IM, Fahey, TJ, Zarnegar, R, Hsu, YMS, Hsu, JM, van Basien, K, Gaudet, I, Law, P, Kim, NJ, von Hofe, E & Jin, MM 2020, , Scientific Reports, vol. 10, no. 1, 12733. https://doi.org/10.1038/s41598-020-69586-8

PD1 Blockade Enhances ICAM1-Directed CAR T Therapeutic Efficacy in Advanced Thyroid Cancer
Gray, KD, McCloskey, JE, Vedvyas, Y, Kalloo, OR, Eshaky, SE, Yang, Y, Shevlin, E, Zaman, M, Ullmann, TM, Liang, H, Stefanova, D, Christos, PJ, Scognamiglio, T, Tassler, AB, Zarnegar, R, Fahey, TJ, Jin, MM & Min, IM 2020, , Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 26, no. 22, pp. 6003-6016. https://doi.org/10.1158/1078-0432.CCR-20-1523

PD1 Blockade Enhances ICAM1-Directed CAR T Therapeutic Efficacy in Advanced Thyroid Cancer
Gray, KD, McCloskey, JE, Vedvyas, Y, Kalloo, OR, Eshaky, SE, Yang, Y, Shevlin, E, Zaman, M, Ullmann, TM, Liang, H, Stefanova, D, Christos, PJ, Scognamiglio, T, Tassler, AB, Zarnegar, R, Fahey, TJ, Jin, MM & Min, IM 2020, , Clinical Cancer Research, vol. 26, no. 22, pp. 6003-6016. https://doi.org/10.1158/1078-0432.CCR-20-1523, https://doi.org/10.1158/1078-0432.CCR-20-1523

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