Miguel Valderrábano, MD, FACC

Lois and Carl Davis Centennial Chair, DeBakey Heart & Vascular Center
Professor of Cardiology, Institute for Academic Medicine
Associate Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Research Lab


Biography

Dr. Valderrábano came to Houston from Los Angeles where he was director of the Implanted Devices Clinic at the UCLA Cardiac Arrhythmia Center and assistant professor of medicine at UCLA Medical Center.

Dr. Valderrábano received his medical degree from Universidad Autónoma de Madrid (UAM) School of Medicine in Madrid, Spain, and internal medicine training at UCLA. He completed his cardiology and electrophysiology training at Cedars-Sinai Medical Center in Los Angeles, where he was chief cardiology fellow. He then joined the faculty at the David Geffen School of Medicine at UCLA.

Description of Research

Dr. Valderrábano’s research and clinical interests focus on finding new and more effective treatments for atrial fibrillation, including epicardial mapping and ablation. His research has been funded by grants from the American Heart Association and the National Institutes of Health (NIH).

Areas Of Expertise

Atrial fibrillation Epicardial mapping Ablation
Education & Training

Research Fellowship, Cedar-Sinai Medical Center and UCLA SCOR Group
Clinical Fellowship, Cedars-Sinai Medical Center
Internship, UCLA - West Los Angeles VA Medical Center
Residency
MD, Universidad Autónoma de Madrid
Active Clinical Trials

PREVAIL CAP2

NCT01182441


R01 resubmission- VOM clinical trial

NCT01898221

Publications

Left Atrial Appendage Occlusion Device-Related Thrombus: What We Know and What We Need to Know *
Valderrábano, M 2018, JACC: Clinical Electrophysiology, vol. 4, no. 12, pp. 1638-1639. https://doi.org/10.1016/j.jacep.2018.10.018

Validating Left Atrial Low Voltage Areas During Atrial Fibrillation and Atrial Flutter Using Multielectrode Automated Electroanatomic Mapping
Rodríguez-Mañero, M, Valderrábano, M, Baluja, A, Kreidieh, O, Martínez-Sande, JL, García-Seara, J, Saenen, J, Iglesias-Álvarez, D, Bories, W, Villamayor-Blanco, LM, Pereira-Vázquez, M, Lage, R, Álvarez-Escudero, J, Heidbuchel, H, González-Juanatey, JR & Sarkozy, A 2018, JACC: Clinical Electrophysiology, vol. 4, no. 12, pp. 1541-1552. https://doi.org/10.1016/j.jacep.2018.08.015

Prospective Multicenter Experience With Cooled Radiofrequency Ablation Using High Impedance Irrigant to Target Deep Myocardial Substrate Refractory to Standard Ablation
Nguyen, DT, Tzou, WS, Sandhu, A, Gianni, C, Anter, E, Tung, R, Valderrábano, M, Hranitzky, P, Soeijma, K, Saenz, L, Garcia, FC, Tedrow, UB, Miller, JM, Gerstenfeld, EP, Burkhardt, JD, Natale, A & Sauer, WH 2018, JACC: Clinical Electrophysiology, vol. 4, no. 9, pp. 1176-1185. https://doi.org/10.1016/j.jacep.2018.06.021

Left Atrial Appendage Occlusion Device–Related Thrombus: Certainties and Uncertainties *
Valderrábano, M 2018, Journal of the American College of Cardiology, vol. 71, no. 14, pp. 1537-1539. https://doi.org/10.1016/j.jacc.2018.01.077

Robotically Guided Left Ventricular Biopsy to Diagnose Cardiac Sarcoidosis: A Multidisciplinary Innovation Leading to First-in-Human Case
Bhimaraj, A, Trachtenberg, B & Valderrábano, M 2018, Circulation: Heart Failure, vol. 11, no. 3, pp. e004627. https://doi.org/10.1161/CIRCHEARTFAILURE.117.004627

Ligament of Marshall arrhythmogenesis and vein of Marshall ethanol: A problem with a solution
Valderrábano, M 2018, Heart Rhythm, vol. 15, no. 1, pp. 25-27. https://doi.org/10.1016/j.hrthm.2017.09.013

Ablation of atrial fibrillation in patients with Brugada syndrome: A systematic review of the literature
Rodríguez-Mañero, M, Kreidieh, B, Valderrábano, M, Baluja, A, Martínez-Sande, JL, García-Seara, J, Díaz-Fernández, B, Pereira-Vázquez, M, Lage, R, González-Melchor, L, Fernández-López, XA & González-Juanatey, JR 2018, Journal of Arrhythmia. https://doi.org/10.1002/joa3.12113

Successful ablation of premature ventricular contractions originating from the inferoseptal process of the left ventricle using a coronary sinus approach
Tavares, L, Dave, A & Valderrábano, M 2018, HeartRhythm Case Reports. https://doi.org/10.1016/j.hrcr.2018.05.008

Nanoparticles administered intrapericardially enhance payload myocardial distribution and retention
Segura-Ibarra, V, Cara, FE, Wu, S, Iruegas-Nunez, DA, Wang, S, Ferrari, M, Ziemys, A, Valderrábano, M & Blanco, E 2017, Journal of Controlled Release, vol. 262, pp. 18-27. https://doi.org/10.1016/j.jconrel.2017.07.012

Approaches to Left Atrial Appendage Closure: Device Design, Performance, and Limitations
Dave, AS & Valderrábano, M 2017, Methodist DeBakey Cardiovascular Journal, vol. 13, no. 3, pp. 106-113. https://doi.org/10.14797/mdcj-13-3-106

The Human Left Atrial Venous Circulation as a Vascular Route for Atrial Pharmacological Therapies. Effects of Ethanol Infusion
Valderrábano, M, Morales, PF, Rodríguez-Mañero, M, Lloves, C, Schurmann, PA & Dave, A 2017, JACC: Clinical Electrophysiology. https://doi.org/10.1016/j.jacep.2017.02.022

Multipolar electrode spline embolization
Hussain, MA & Valderrábano, M 2017, HeartRhythm Case Reports. https://doi.org/10.1016/j.hrcr.2017.10.014

The Authors Reply:
Kitkungvan, D, Valderrabano, M & Shah, DJ 2016, JACC: Cardiovascular Imaging, vol. 9, no. 12, pp. 1476. https://doi.org/10.1016/j.jcmg.2016.10.002

TCT-26 Long-Term Event Rates for Left Atrial Appendage Closure with WATCHMAN: PROTECT AF 5 Year and PREVAIL 3 Year Follow-up
Reddy, V, Price, M, Valderrabano, M, Sanchez, J, Doshi, S, Gordon, N & Holmes, D 2016, Journal of the American College of Cardiology, vol. 68, no. 18S, pp. B11. DOI: 10.1016/j.jacc.2016.09.046

TCT-615 Do patients with CKD benefit from Left Atrial Appendage Closure (LAAC) with WATCHMAN? Insights from PROTECT AF
Valderrabano, M, Price, M, Reddy, V, Buchbinder, M, Holmes, D, Sievert, H, Turi, Z, Gordon, N, Mullin, C, Sick, P & Best, P 2016, Journal of the American College of Cardiology, vol. 68, no. 18S, pp. B251. DOI: 10.1016/j.jacc.2016.09.756

Position-Dependent Ventricular Tachycardia Related to Peripherally Inserted Central Venous Catheter
Alvarez, P, Schurmann, P, Smith, M, Valderrábano, M & Lin, CH 2016, Methodist DeBakey Cardiovascular Journal, vol. 12, no. 3, pp. 177-178. https://doi.org/10.14797/mdcj-12-3-177

Clinical neurocardiology defining the value of neuroscience-based cardiovascular therapeutics
Shivkumar, K, Ajijola, OA, Anand, I, Armour, JA, Chen, PS, Esler, M, De Ferrari, GM, Fishbein, MC, Goldberger, JJ, Harper, RM, Joyner, MJ, Khalsa, SS, Kumar, R, Lane, R, Mahajan, A, Po, S, Schwartz, PJ, Somers, VK, Valderrabano, M, Vaseghi, M & Zipes, DP 2016, Journal of Physiology, vol. 594, no. 14, pp. 3911-3954. https://doi.org/10.1113/JP271870

Retrograde coronary venous ethanol infusion for ablation of refractory ventricular tachycardia
Kreidieh, B, Rodríguez-Mañero, M, Schurmann, PA, Ibarra-Cortez, SH, Dave, AS & Valderrábano, M 2016, Circulation: Arrhythmia and Electrophysiology, vol. 9, no. 7. https://doi.org/10.1161/CIRCEP.116.004352

Ablation of Inappropriate Sinus Tachycardia. A Systematic Review of the Literature
Rodríguez-Mañero, M, Kreidieh, B, Al Rifai, M, Ibarra-Cortez, S, Schurmann, P, Álvarez, PA, Fernández-López, XA, García-Seara, J, Martínez-Sande, L, González-Juanatey, JR & Valderrábano, M 2016, JACC: Clinical Electrophysiology. https://doi.org/10.1016/j.jacep.2016.09.014

Clinical Implications of Leaks Following Left Atrial Appendage Ligation with the LARIAT Device
Gianni, C, Di Biase, L, Trivedi, C, Mohanty, S, Gökoglan, Y, Günes, MF, Bai, R, Al-Ahmad, A, Burkhardt, JD, Horton, RP, Krumerman, AK, Palma, EC, Valderrábano, M, Gibson, D, Price, MJ & Natale, A 2016, JACC: Cardiovascular Interventions, vol. 9, no. 10, pp. 1051-1057. https://doi.org/10.1016/j.jcin.2016.01.038