Miguel Valderrábano, MD, FACC

Lois and Carl Davis Centennial Chair, DeBakey Heart & Vascular Center
Professor of Cardiology, Academic Institute
Associate Member, Research Institute
Houston Methodist
Weill Cornell Medical College

Research Lab


Dr. Valderrábano came to Houston from Los Angeles where he was director of the Implanted Devices Clinic at the UCLA Cardiac Arrhythmia Center and assistant professor of medicine at UCLA Medical Center.

Dr. Valderrábano received his medical degree from Universidad Autónoma de Madrid (UAM) School of Medicine in Madrid, Spain, and internal medicine training at UCLA. He completed his cardiology and electrophysiology training at Cedars-Sinai Medical Center in Los Angeles, where he was chief cardiology fellow. He then joined the faculty at the David Geffen School of Medicine at UCLA.

Description of Research

Dr. Valderrábano’s research and clinical interests focus on finding new and more effective treatments for atrial fibrillation, including epicardial mapping and ablation. His research has been funded by grants from the American Heart Association and the National Institutes of Health (NIH).

Areas Of Expertise

Atrial fibrillation Epicardial mapping Ablation
Education & Training

Research Fellowship, Cedar-Sinai Medical Center and UCLA SCOR Group
Clinical Fellowship, Cedars-Sinai Medical Center
Internship, UCLA - West Los Angeles VA Medical Center
MD, Universidad Autónoma de Madrid
Active Clinical Trials




NS5806 Induces Electromechanically Discordant Alternans and Arrhythmogenic Voltage-Calcium Dynamics in the Isolated Intact Rabbit Heart
Wang, S, Rodríguez-Mañero, M, Ibarra-Cortez, SH, Kreidieh, B, Valderrábano, L, Hemam, M, Tavares, L, Blanco, E & Valderrábano, M 2019, Frontiers in Physiology, vol. 10, 1509. https://doi.org/10.3389/fphys.2019.01509

Vein of Marshall ethanol infusion for persistent atrial fibrillation: VENUS and MARS clinical trial design
Valderrábano, M, Peterson, LE, Bunge, R, Prystash, M, Dave, A, Nagueh, S & Kleiman, N 2019, American Heart Journal, vol. 215, pp. 52-61. https://doi.org/10.1016/j.ahj.2019.04.022

Clinical impact of ethanol infusion into the vein of Marshall on the mitral isthmus area evaluated by atrial electrograms recorded inside the coronary sinus
Kawaguchi, N, Okishige, K, Yamauchi, Y, Kurabayashi, M, Nakamura, T, Keida, T, Sasano, T, Hirao, K & Valderrábano, M 2019, Heart Rhythm, vol. 16, no. 7, pp. 1030-1038. https://doi.org/10.1016/j.hrthm.2019.01.031

Evidence of relevant electrical connection between the left atrial appendage and the great cardiac vein during catheter ablation of atrial fibrillation
Di Biase, L, Romero, J, Briceno, D, Valderrábano, M, Sanchez, JE, Della Rocca, DG, Mohanty, P, Horton, R, Gallinghouse, GJ, Mohanty, S, Trivedi, C, Beheiry, S, Gianni, C, Elayi, CS, Burkhardt, JD & Natale, A 2019, Heart Rhythm, vol. 16, no. 7, pp. 1039-1046. https://doi.org/10.1016/j.hrthm.2019.02.009

Cardiac Afferent Denervation Abolishes Ganglionated Plexi and Sympathetic Responses to Apnea
Tavares, L, Rodríguez-Mañero, M, Kreidieh, B, Ibarra-Cortez, SH, Chen, J, Wang, S, Markovits, J, Barrios, R & Valderrábano, M 2019, Circulation. Arrhythmia and electrophysiology, vol. 12, no. 6, pp. e006942. https://doi.org/10.1161/CIRCEP.118.006942

Left atrial appendage closure with the Watchman device using intracardiac vs transesophageal echocardiography: Procedural and cost considerations
Hemam, ME, Kuroki, K, Schurmann, PA, Dave, A, Rodríguez, DA, Sáenz, LC, Reddy, VY & Valderrábano, M 2019, Heart Rhythm, vol. 16, no. 3, pp. 334-342. https://doi.org/10.1016/j.hrthm.2018.12.013

Retrograde venous ethanol ablation for ventricular tachycardia
Tavares, L & Valderrábano, M 2019, Heart Rhythm, vol. 16, no. 3, pp. 478-483. https://doi.org/10.1016/j.hrthm.2018.09.010

Permanent His-bundle pacing from the right atrium in patients with prosthetic tricuspid valve
Fuentes Rojas, SC, Schurmann, PA, Rodríguez-Mañero, M, Lustgarten, D & Valderrábano, M 2019, HeartRhythm Case Reports. https://doi.org/10.1016/j.hrcr.2019.01.009

Improving ablation results in persistent AF: Is ethanol the answer?
Valderrábano, M 2019, Journal of Cardiovascular Electrophysiology. https://doi.org/10.1111/jce.13971

Device-Related Thrombus: A Reason for Concern?
Hannawi, B, Beg, F, Valderrábano, M & Kurrelmeyer, KM 2019, Methodist DeBakey cardiovascular journal, vol. 15, no. 1, pp. 77-80. https://doi.org/10.14797/mdcj-15-1-77

A Fluttering Heart: A Storm is Brewing
Rothstein, P & Valderrábano, M 2019, Methodist DeBakey cardiovascular journal, vol. 15, no. 1, pp. e3.

Left Atrial Appendage Occlusion Device-Related Thrombus: What We Know and What We Need to Know *
Valderrábano, M 2018, JACC: Clinical Electrophysiology, vol. 4, no. 12, pp. 1638-1639. https://doi.org/10.1016/j.jacep.2018.10.018

Validating Left Atrial Low Voltage Areas During Atrial Fibrillation and Atrial Flutter Using Multielectrode Automated Electroanatomic Mapping
Rodríguez-Mañero, M, Valderrábano, M, Baluja, A, Kreidieh, O, Martínez-Sande, JL, García-Seara, J, Saenen, J, Iglesias-Álvarez, D, Bories, W, Villamayor-Blanco, LM, Pereira-Vázquez, M, Lage, R, Álvarez-Escudero, J, Heidbuchel, H, González-Juanatey, JR & Sarkozy, A 2018, JACC: Clinical Electrophysiology, vol. 4, no. 12, pp. 1541-1552. https://doi.org/10.1016/j.jacep.2018.08.015

Loperamide Mimicking Brugada Pattern
Rojas, SF, Oglat, A, Bonilla, HMG, Jeroudi, O, Sharp, W, Valderrábano, M & Schurmann, PA 2018, Methodist DeBakey cardiovascular journal, vol. 14, no. 4. https://doi.org/10.14797/mdcj-14-4-e1

Prospective Multicenter Experience With Cooled Radiofrequency Ablation Using High Impedance Irrigant to Target Deep Myocardial Substrate Refractory to Standard Ablation
Nguyen, DT, Tzou, WS, Sandhu, A, Gianni, C, Anter, E, Tung, R, Valderrábano, M, Hranitzky, P, Soeijma, K, Saenz, L, Garcia, FC, Tedrow, UB, Miller, JM, Gerstenfeld, EP, Burkhardt, JD, Natale, A & Sauer, WH 2018, JACC: Clinical Electrophysiology, vol. 4, no. 9, pp. 1176-1185. https://doi.org/10.1016/j.jacep.2018.06.021

Sudden death in patients with coronary heart disease without severe systolic dysfunction
Chatterjee, NA, Moorthy, MV, Pester, J, Schaecter, A, Panicker, GK, Narula, D, Lee, DC, Goldberger, JJ, Kadish, A, Cook, NR, Albert, CM, Elbert, CM, Mahal, S, Sobolski, J, Danciu, S, Dyke, C, Phang, R, Wolinsky, D, Biederman, R, McLaurin, B, Trichon, B, Serfas, D, Aslam, A, Bugni, W, Hany, A, Jiang, L, Marais, H, Durr, S, Reinoehl, J, Graham, S, Sadler, D, Erenrich, N, Spencer, R, Griffin, JEA, Geohas, C, Treasure, CB, Baki, T, Huneycutt, D, Saliba, W, Svinarich, JT, Whang, W, Jetty, P, Shanes, J, McGarvey, J, Hankins, S, White, LL, DeLurgio, D, Karunaratne, H, Flores, E, Gillespie, E, McKenzie, J, Staniloae, C, Altschuller, A, Schuger, C, Radin, M, Pohost, G, Myers, M, Bunch, TJ, Wickemeyer, W, Mendelson, R, Berger, R, Ross, T, Sumner, A, Arcement, L, Malik, B, Claxton, N, Rohr, K, Weiss, R, Garcia-Rinaldi, R, Kazmierski, J, Rosenbaum, D, Blonder, R, Ramanathan, K, ONeill, G, Cochran, K, Kaufman, E, Costantini, O, Hustead, S, Sahul, Z, Bengston, J, Lader, E, Nora, M, Gornick, C, Adabag, S, Tishler, S, Klein, S, Lamas, G, Baig, M, Ratliff, M, Iwai, S, Johnson, G, Oliver, T, Langer, M, Ahn, J, Silver, KH, Mattson, SE, Schmidt, J, Ramanathan, PK, Heitner, J, Riba, A, Thadani, U, Shah, S, Sandler, D, Bello, D, Mostel, E, Patel, R, Simpson, P, Hack, T, Shoultz, C, Figueredo, R, Atieh, M, Herre, J, Bhasin, M, Gauri, A, Gottlieb, C, Hotvedt, P, Chaudhry, M, Greenberg, S, Tsai, WK, Averbach, M, Cheong, B, Mittal, S, Baker, J, McGrew, F, Kraus, D, Skopicki, H, Lee, S, Gredler, F, Islam, J, Mohiuddin, S, Valderrábano, M, Nasir, Jr. N, Anderson, D, Niebauer, M, Colon-Hernandez, P, Mackall, J, Sandhu, R, Ott, P, Nayak, H, Dunlap, S, Aranda, J, Hsu, S, Owens, S, See, V, Menees, D, Flaker, G, Saba, S, Fong, M, Aktas, M, OBrien, T, Bernstein, V, Saavedra, P, Koshy, M, Whalen, S, Eldadah, Z, Haines, D & Marzo, K 2018, JAMA Cardiology, vol. 3, no. 7, pp. 591-600. https://doi.org/10.1001/jamacardio.2018.1049

Left Atrial Appendage Occlusion Device–Related Thrombus: Certainties and Uncertainties *
Valderrábano, M 2018, Journal of the American College of Cardiology, vol. 71, no. 14, pp. 1537-1539. https://doi.org/10.1016/j.jacc.2018.01.077

Robotically Guided Left Ventricular Biopsy to Diagnose Cardiac Sarcoidosis: A Multidisciplinary Innovation Leading to First-in-Human Case
Bhimaraj, A, Trachtenberg, BH & Valderrábano, M 2018, Circulation: Heart Failure, vol. 11, no. 3, pp. e004627. https://doi.org/10.1161/CIRCHEARTFAILURE.117.004627

Successful ablation of premature ventricular contractions originating from the inferoseptal process of the left ventricle using a coronary sinus approach
Tavares, L, Dave, A & Valderrábano, M 2018, HeartRhythm Case Reports. https://doi.org/10.1016/j.hrcr.2018.05.008

Ligament of Marshall arrhythmogenesis and vein of Marshall ethanol: A problem with a solution
Valderrábano, M 2018, Heart Rhythm, vol. 15, no. 1, pp. 25-27. https://doi.org/10.1016/j.hrthm.2017.09.013

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