Miguel Valderrábano, MD, FACC

Lois and Carl Davis Centennial Chair, DeBakey Heart & Vascular Center
Professor of Cardiology, Academic Institute
Associate Member, Research Institute
Houston Methodist
Weill Cornell Medical College

Research Lab


Dr. Valderrábano came to Houston from Los Angeles where he was director of the Implanted Devices Clinic at the UCLA Cardiac Arrhythmia Center and assistant professor of medicine at UCLA Medical Center.

Dr. Valderrábano received his medical degree from Universidad Autónoma de Madrid (UAM) School of Medicine in Madrid, Spain, and internal medicine training at UCLA. He completed his cardiology and electrophysiology training at Cedars-Sinai Medical Center in Los Angeles, where he was chief cardiology fellow. He then joined the faculty at the David Geffen School of Medicine at UCLA.

Description of Research

Dr. Valderrábano’s research and clinical interests focus on finding new and more effective treatments for atrial fibrillation, including epicardial mapping and ablation. His research has been funded by grants from the American Heart Association and the National Institutes of Health (NIH).

Areas Of Expertise

Atrial fibrillation Epicardial mapping Ablation
Education & Training

Research Fellowship, Cedar-Sinai Medical Center and UCLA SCOR Group
Clinical Fellowship, Cedars-Sinai Medical Center
Internship, UCLA - West Los Angeles VA Medical Center
MD, Universidad Autónoma de Madrid
Active Clinical Trials




Left atrial appendage occlusion using intracardiac echocardiography
Patel, A, Venkataraman, R, Schurmann, P, Dave, A & Valderrábano, M 2021, , Heart Rhythm, vol. 18, no. 2, pp. 313-317. https://doi.org/10.1016/j.hrthm.2020.09.021

Double-balloon technique for retrograde venous ethanol ablation of ventricular arrhythmias in the absence of suitable intramural veins
Da-Wariboko, A, Lador, A, Tavares, L, Dave, AS, Schurmann, PA, Peichl, P, Kautzner, J, Papiashvili, G & Valderrábano, M 2020, , Heart Rhythm, vol. 17, no. 12, pp. 2126-2134. https://doi.org/10.1016/j.hrthm.2020.05.027

Trans–coronary sinus puncture for catheter ablation and left atrial appendage closure device implantation in a patient with dextrocardia and persistent right superior vena cava
Lador, A, Patel, A & Valderrábano, M 2020, , HeartRhythm Case Reports, vol. 6, no. 12, pp. 903-906. https://doi.org/10.1016/j.hrcr.2020.08.013

Effect of Catheter Ablation with Vein of Marshall Ethanol Infusion vs Catheter Ablation Alone on Persistent Atrial Fibrillation: The VENUS Randomized Clinical Trial
Valderrábano, M, Peterson, LE, Swarup, V, Schurmann, PA, Makkar, A, Doshi, RN, Delurgio, D, Athill, CA, Ellenbogen, KA, Natale, A, Koneru, J, Dave, AS, Giorgberidze, I, Afshar, H, Guthrie, ML, Bunge, R, Morillo, CA & Kleiman, NS 2020, , JAMA - Journal of the American Medical Association, vol. 324, no. 16, pp. 1620-1628. https://doi.org/10.1001/jama.2020.16195

Intramural Venous Ethanol Infusion for Refractory Ventricular Arrhythmias: Outcomes of a Multicenter Experience
Tavares, L, Lador, A, Fuentes, S, Da-wariboko, A, Blaszyk, K, Malaczynska-Rajpold, K, Papiashvili, G, Korolev, S, Peichl, P, Kautzner, J, Webber, M, Hooks, D, Rodríguez-Mañero, M, Di Toro, D, Labadet, C, Sasaki, T, Okishige, K, Patel, A, Schurmann, PA, Dave, AS, Rami, TG & Valderrábano, M 2020, , JACC: Clinical Electrophysiology, vol. 6, no. 11, pp. 1420-1431. https://doi.org/10.1016/j.jacep.2020.07.023

Modern mapping and ablation techniques to treat ventricular arrhythmias from the left ventricular summit and interventricular septum
Romero, J, Shivkumar, K, Valderrabano, M, Diaz, JC, Alviz, I, Briceno, D, Natale, A & Di Biase, L 2020, , Heart Rhythm, vol. 17, no. 9, pp. 1609-1620. https://doi.org/10.1016/j.hrthm.2020.04.026

Structure Predicts (Dys)Function: Atrial Fibrosis, Function, and Incident Atrial Fibrillation
Valderrábano, M & Shah, DJ 2020, , JACC: Cardiovascular Imaging, vol. 13, no. 8, pp. 1701-1703. https://doi.org/10.1016/j.jcmg.2020.04.023

Ablation strategies for intramural ventricular arrhythmias
Neira, V, Santangeli, P, Futyma, P, Sapp, J, Valderrabano, M, Garcia, F & Enriquez, A 2020, , Heart Rhythm, vol. 17, no. 7, pp. 1176-1184. https://doi.org/10.1016/j.hrthm.2020.02.010

QT interval prolongation and torsade de pointes induced by left ventricular pacing rescued by His bundle pacing
Lador, A & Valderrábano, M 2020, , HeartRhythm Case Reports, vol. 6, no. 6, pp. 325-328. https://doi.org/10.1016/j.hrcr.2020.02.010

Incessant PVCs and Cardiomyopathy: Think Outside the Box
Senapati, A, Rojas, SF, Kurrelmeyer, K, Kassi, M, Valderrábano, M, Shah, DJ & Al-Mallah, MH 2020, , Methodist DeBakey cardiovascular journal, vol. 16, no. 2, pp. e1. https://doi.org/10.14797/mdcj-16-2-e1

Chemical mapping as a predictor of vein of Marshall ethanol ablative effects
Okishige, K, Shigeta, T, Nishimura, T, Nakamura, RA, Hirao, T, Yoshida, H, Yamauchi, Y, Keida, T, Sasano, T, Hirao, K & Valderrábano, M 2020, , PACE - Pacing and Clinical Electrophysiology, vol. 43, no. 1, pp. 47-53. https://doi.org/10.1111/pace.13839

Device Therapy for Sudden Cardiac Death Prophylaxis After Acute Coronary Syndrome: When and Why?
Beg, F, Valderrabano, M & Schurmann, P 2020, , Current Cardiology Reports, vol. 22, no. 1, 4. https://doi.org/10.1007/s11886-020-1255-0

Comparative study of cryoballoon versus radiofrequency for pulmonary vein isolation when combined with vein of marshall ethanol infusion for paroxysmal atrial fibrillation
Okishige, K, Kawaguchi, N, Iwai, S, Yamauchi, Y, Keida, T, Sasano, T, Hirao, K & Valderrabano, M 2020, , Journal of Atrial Fibrillation, vol. 12, no. 5, pp. 1-8. https://doi.org/10.4022/JAFIB.2253

NS5806 Induces Electromechanically Discordant Alternans and Arrhythmogenic Voltage-Calcium Dynamics in the Isolated Intact Rabbit Heart
Wang, S, Rodríguez-Mañero, M, Ibarra-Cortez, SH, Kreidieh, B, Valderrábano, L, Hemam, M, Tavares, L, Blanco, E & Valderrábano, M 2019, , Frontiers in Physiology, vol. 10, 1509. https://doi.org/10.3389/fphys.2019.01509

Vein of Marshall ethanol infusion for persistent atrial fibrillation: VENUS and MARS clinical trial design
Valderrábano, M, Peterson, LE, Bunge, R, Prystash, M, Dave, AS, Nagueh, S & Kleiman, NS 2019, , American Heart Journal, vol. 215, pp. 52-61. https://doi.org/10.1016/j.ahj.2019.04.022

Clinical impact of ethanol infusion into the vein of Marshall on the mitral isthmus area evaluated by atrial electrograms recorded inside the coronary sinus
Kawaguchi, N, Okishige, K, Yamauchi, Y, Kurabayashi, M, Nakamura, T, Keida, T, Sasano, T, Hirao, K & Valderrábano, M 2019, , Heart Rhythm, vol. 16, no. 7, pp. 1030-1038. https://doi.org/10.1016/j.hrthm.2019.01.031

Evidence of relevant electrical connection between the left atrial appendage and the great cardiac vein during catheter ablation of atrial fibrillation
Di Biase, L, Romero, J, Briceno, D, Valderrabano, M, Sanchez, JE, Della Rocca, DG, Mohanty, P, Horton, R, Gallinghouse, GJ, Mohanty, S, Trivedi, C, Beheiry, S, Gianni, C, Elayi, CS, Burkhardt, JD & Natale, A 2019, , Heart Rhythm, vol. 16, no. 7, pp. 1039-1046. https://doi.org/10.1016/j.hrthm.2019.02.009

Cardiac Afferent Denervation Abolishes Ganglionated Plexi and Sympathetic Responses to Apnea: Implications for Atrial Fibrillation
Tavares, L, Rodríguez-Mañero, M, Kreidieh, B, Ibarra-Cortez, SH, Chen, J, Wang, S, Markovits, J, Barrios, R & Valderrábano, M 2019, , Circulation: Arrhythmia and Electrophysiology, vol. 12, no. 6, e006942. https://doi.org/10.1161/CIRCEP.118.006942

Permanent His-bundle pacing from the right atrium in patients with prosthetic tricuspid valve
Fuentes Rojas, SC, Schurmann, PA, Rodríguez-Mañero, M, Lustgarten, D & Valderrábano, M 2019, , HeartRhythm Case Reports, vol. 5, no. 5, pp. 244-246. https://doi.org/10.1016/j.hrcr.2019.01.009

Retrograde venous ethanol ablation for ventricular tachycardia
Tavares, L & Valderrábano, M 2019, , Heart Rhythm, vol. 16, no. 3, pp. 478-483. https://doi.org/10.1016/j.hrthm.2018.09.010