Masayoshi Takashima, MD, FACS

Professor of Otolaryngology, Academic Institute
Full Clinical Member, Research Institute
Chair, Department of Otolaryngology
Houston Methodist
Weill Cornell Medical College


After obtaining his bachelor’s at Rice University, Dr. Takashima received his medical degree from Baylor College of Medicine where he also served his general surgery internship and residency in otolaryngology—head and neck surgery.

He spent several years in Denver at National Jewish Medical Center, the University of Colorado Health Sciences Center and the Veteran’s Affairs Medical Center and 14 years at Baylor College of Medicine before taking the leadership role of chair in the Department of Otolaryngology at Houston Methodist Hospital. 

Dr. Takashima is double boarded in Otolaryngology – Head and Neck Surgery and Sleep Medicine, and also received advanced training in rhinology, sinus and anterior skull base surgery.

Description of Research

Dr. Takashima specializes in minimally-invasive sinus procedures, sleep apnea surgery, and endoscopic skull base surgery. His research focuses on chronic rhinosinusitis, primarily to identify how alterations in the sinus biome may affect overall sinus health.

As department chair, Dr. Takashima leads a group of otolaryngologists with expertise in facial plastic and reconstructive surgery, head and neck cancers, hearing and balance diseases, anterior and lateral skull base tumors, and voice and swallowing disorders. His focus is to enhance collaboration with clinicians and researchers across the hospital system, as well as improve surgical training and translational research opportunities through technological and digital innovations.


Effect of Radiofrequency Neurolysis on the Symptoms of Chronic Rhinitis: A Randomized Controlled Trial
Stolovitzky, JP, Ow, RA, Silvers, SL, Bikhazi, NB, Johnson, CD & Takashima, M 2021, , OTO Open, vol. 5, no. 3.

Obstructive Sleep Apnea
Lin, K & Takashima, M 2020, . in RD Kellerman & D Rakel (eds), Conn’s Current Therapy 2021. 1 edn, Elsevier.

A Remarkable Response of Granulomatous Hypophysitis to Infliximab in a Patient With a Background of Crohn's Disease—A Case Report
Force, BK, Vogel, TP, Nguyen, DM, Heck, KA, Sebastian, S, Takashima, M, Yoshor, D & Samson, SL 2020, , Frontiers in Endocrinology, vol. 11, 350.

An Effective and Practical Fluid Restriction Protocol to Decrease the Risk of Hyponatremia and Readmissions After Transsphenoidal Surgery
Winograd, D, Staggers, KA, Sebastian, S, Takashima, M, Yoshor, D & Samson, SL 2020, , Neurosurgery, vol. 87, no. 4, pp. 761-769.

Telemedicine in Otolaryngology in the COVID-19 Era: Initial Lessons Learned
Ohlstein, JF, Garner, J & Takashima, M 2020, , Laryngoscope, vol. 130, no. 11, pp. 2568-2573.

Real-time hemodynamic effects of 1:100,000 and 1:200,000 injectable epinephrine and placement of topical 1:1000 epinephrine pledgets in patients undergoing endoscopic sinus and skull-base surgery: a randomized, prospective study
Ahmed, OG, Yu, J, Choi, JS, Yim, MT, Yoshor, D & Takashima, M 2019, , International Forum of Allergy and Rhinology, vol. 10, no. 2, pp. 141-146.

Evaluating real-time effects of topical 1:1000 epinephrine in endoscopic sinus and skull-base surgery on hemodynamic parameters through intraoperative arterial line monitoring
Yim, MT, Ahmed, OG & Takashima, M 2017, , International Forum of Allergy and Rhinology, vol. 7, no. 11, pp. 1065-1069.

In Reference to Hyoid surgery alone for obstructive sleep apnea: A systematic review and meta-analysis
Fox, DP & Takashima, M 2017, , Laryngoscope, vol. 127, no. 1, pp. E53.

Interventional Drug-Induced Sleep Endoscopy: A novel technique to guide surgical planning for obstructive sleep apnea
Victores, AJ, Olson, K & Takashima, M 2017, , Journal of Clinical Sleep Medicine, vol. 13, no. 2, pp. 169-174.

Role of intraoperative ropivacaine in adult post-tonsillectomy pain control: A randomized controlled trial
Yao, WC, Corbitt, CA & Takashima, M 2017, , Ear, Nose and Throat Journal, vol. 96, no. 4-5, pp. E39.

Endoscopic repair technique for traumatic penetrating injuries of the clivus
Liebelt, BD, Boghani, Z, Haider, AS & Takashima, M 2016, , Journal of Clinical Neuroscience, vol. 28, pp. 152-156.

Endoscopic approach to pituitary tumors
Ahmed, OG, Victores, AJ & Takashima, M 2016, , International Ophthalmology Clinics, vol. 56, no. 1, pp. 29-39.

Thyroid eye disease: Optic neuropathy and orbital decompression
Victores, AJ & Takashima, M 2016, , International Ophthalmology Clinics, vol. 56, no. 1, pp. 69-79.

Staining intraoperative topical solutions with fluorescein: Enhancing the safety of sinus surgery
Yao, WC, Regone, RM & Takashima, M 2015, , International Forum of Allergy and Rhinology, vol. 5, no. 9, pp. 870-874.

Electronic health records and resident workflow: A time-motion study of otolaryngology residents
Victores, AJ, Coggins, K & Takashima, M 2015, , Laryngoscope, vol. 125, no. 3, pp. 594-598.

Three-dimensional sinus imaging as an adjunct to two-dimensional imaging to accelerate education and improve spatial orientation
Yao, WC, Regone, RM, Huyhn, N, Butler, EB & Takashima, M 2014, , Laryngoscope, vol. 124, no. 3, pp. 596-601.

Usefulness of sleep endoscopy in predicting positional obstructive sleep apnea
Victores, AJ, Hamblin, J, Gilbert, J, Switzer, C & Takashima, M 2014, , Otolaryngology - Head and Neck Surgery (United States), vol. 150, no. 3, pp. 487-493.

Management of obstructive sleep apnea in the indigent population: A deviation of standard of care?
Hamblin, JS, Sandulache, VC, Alapat, PM & Takashima, M 2014, , Otolaryngology - Head and Neck Surgery (United States), vol. 150, no. 3, pp. 346-347.

Prospective trial of a short hospital stay protocol after endoscopic endonasal pituitary adenoma surgery
Thomas, JG, Gadgil, N, Samson, SL, Takashima, M & Yoshor, D 2014, , World neurosurgery, vol. 81, no. 3-4, pp. 576-583.

A case for the standardized letter of recommendation in otolaryngology residency selection
Messner, A, Teng, M, Shimahara, E, Abaza, M, Franzese, C, Goebel, J, Gray, S, Joe, S, Ruckenstein, M, Takashima, M, Wax, M & Zacharek, M 2014, , Laryngoscope, vol. 124, no. 1, pp. 2-3.