Belen Pascual

Belen Pascual, PhD

Associate Research Professor of Neurology, Academic Institute
Associate Research Member, Research Institute
Co-Director, Neuroimaging, Nantz National Alzheimer Center
Houston Methodist
Weill Cornell Medical College


Neuroimaging Research Lab


Areas Of Expertise

Neuroimaging Neuropsychology Alzheimer's Disease Neuroinflammation Frontotemporal Degeneration Neurodegenerative Diseases Brain Functional Organization Memory Disorders Language Architecture
Publications

The contribution of behavioral features to caregiver burden in FTLD spectrum disorders
the ALLFTD consortium 2022, , Alzheimers and Dementia, vol. 18, no. 9, pp. 1635-1649. https://doi.org/10.1002/alz.12494

Imaging Neuroinflammation in Neurodegenerative Disorders
Masdeu, JC, Pascual, B & Fujita, M 2022, , Journal of nuclear medicine : official publication, Society of Nuclear Medicine, vol. 63, no. Suppl 1, pp. 45S-52S. https://doi.org/10.2967/jnumed.121.263200

Imaging Neuroinflammation in Neurodegenerative Disorders
Masdeu, JC, Pascual, B & Fujita, M 2022, , Journal of nuclear medicine : official publication, Society of Nuclear Medicine, vol. 63, no. Suppl 1, pp. 45S-52S. https://doi.org/10.2967/jnumed.121.263200

Comprehensive cross-sectional and longitudinal analyses of plasma neurofilament light across FTD spectrum disorders
Gendron, TF, Heckman, MG, White, LJ, Veire, AM, Pedraza, O, Burch, AR, Bozoki, AC, Dickerson, BC, Domoto-Reilly, K, Foroud, T, Forsberg, LK, Galasko, DR, Ghoshal, N, Graff-Radford, NR, Grossman, M, Heuer, HW, Huey, ED, Hsiung, GYR, Irwin, DJ, Kaufer, DI, Leger, GC, Litvan, I, Masdeu, JC, Mendez, MF, Onyike, CU, Pascual, B, Ritter, A, Roberson, ED, Rojas, JC, Tartaglia, MC, Wszolek, ZK, Rosen, H, Boeve, BF, Boxer, AL & ALLFTD consortium 2022, , Cell Reports Medicine, vol. 3, no. 4, 100607. https://doi.org/10.1016/j.xcrm.2022.100607

Comprehensive cross-sectional and longitudinal analyses of plasma neurofilament light across FTD spectrum disorders
ALLFTD consortium 2022, , Cell Reports Medicine, vol. 3, no. 4, pp. 100607. https://doi.org/10.1016/j.xcrm.2022.100607

Translocator Protein 18 kDa PET Imaging Highlights Asymptomatic Isolated Cerebellar Dysplasia
Pascual, B, Hodics, T, Funk, Q, Cykowski, MD, Nakawah, MO & Masdeu, JC 2022, , Neurology, vol. 98, no. 13, pp. 538-539. https://doi.org/10.1212/WNL.0000000000200221

Proposed research criteria for prodromal behavioural variant frontotemporal dementia
ALLFTD consortium 2022, , Brain, vol. 145, no. 3, pp. 1079-1097. https://doi.org/10.1093/brain/awab365

The PET tracer [11C]MK-6884 quantifies M4 muscarinic receptor in rhesus monkeys and patients with Alzheimer's disease
Li, W, Wang, Y, Lohith, TG, Zeng, Z, Tong, L, Mazzola, R, Riffel, K, Miller, P, Purcell, M, Holahan, M, Haley, H, Gantert, L, Hesk, D, Ren, S, Morrow, J, Uslaner, J, Struyk, A, Wai, JMC, Rudd, MT, Tellers, DM, McAvoy, T, Bormans, G, Koole, M, Van Laere, K, Serdons, K, De Hoon, J, Declercq, R, De Lepeleire, I, Pascual, MB, Zanotti Fregonara, P, Yu, M, Arbones, V, Masdeu, JC, Cheng, A, Hussain, A, Bueters, T, Anderson, MS, Hostetler, ED & Basile, AS 2022, , Science translational medicine, vol. 14, no. 627, eabg3684, pp. eabg3684. https://doi.org/10.1126/scitranslmed.abg3684

The PET tracer [11C]MK-6884 quantifies M4 muscarinic receptor in rhesus monkeys and patients with Alzheimer's disease
Li, W, Wang, Y, Lohith, TG, Zeng, Z, Tong, L, Mazzola, R, Riffel, K, Miller, P, Purcell, M, Holahan, M, Haley, H, Gantert, L, Hesk, D, Ren, S, Morrow, J, Uslaner, J, Struyk, A, Wai, JMC, Rudd, MT, Tellers, DM, McAvoy, T, Bormans, G, Koole, M, Van Laere, K, Serdons, K, De Hoon, J, Declercq, R, De Lepeleire, I, Pascual, MB, Zanotti-Fregonara, P, Yu, M, Arbones, V, Masdeu, JC, Cheng, A, Hussain, A, Bueters, T, Anderson, MS, Hostetler, ED & Basile, AS 2022, , Science translational medicine, vol. 14, no. 627, eabg3684, pp. eabg3684. https://doi.org/10.1126/scitranslmed.abg3684

In Alzheimer-prone brain regions, metabolism and risk-gene expression are strongly correlated
Ye, F, Funk, Q, Rockers, E, Shulman, JM, Masdeu, JC, Pascual, B & Alzheimers Disease Neuroimaging Initiative 2022, , Brain communications, vol. 4, no. 5, pp. fcac216. https://doi.org/10.1093/braincomms/fcac216

The contribution of behavioral features to caregiver burden in FTLD spectrum disorders
ALLFTD consortium 2021, , Alzheimers and Dementia. https://doi.org/10.1002/alz.12494

Recognition memory and divergent cognitive profiles in prodromal genetic frontotemporal dementia
ALLFTD consortium 2021, , Cortex, vol. 139, pp. 99-115. https://doi.org/10.1016/j.cortex.2021.03.006

Neuroinflammation is highest in areas of disease progression in semantic dementia
Pascual, B, Funk, Q, Zanotti Fregonara, P, Cykowski, MD, Veronese, M, Rockers, E, Bradbury, K, Yu, M, Nakawah, MO, Román, GC, Schulz, PE, Arumanayagam, AS, Beers, D, Faridar, A, Fujita, M, Appel, SH & Masdeu, JC 2021, , Brain, vol. 144, no. 5, pp. 1565-1575. https://doi.org/10.1093/brain/awab057

Neuroinflammation is highest in areas of disease progression in semantic dementia
Pascual, B, Funk, Q, Zanotti-Fregonara, P, Cykowski, MD, Veronese, M, Rockers, E, Bradbury, K, Yu, M, Nakawah, MO, Román, GC, Schulz, PE, Arumanayagam, AS, Beers, D, Faridar, A, Fujita, M, Appel, SH & Masdeu, JC 2021, , Brain, vol. 144, no. 5, pp. 1565-1575. https://doi.org/10.1093/brain/awab057

Parametric Mapping for TSPO PET Imaging with Spectral Analysis Impulsive Response Function
Veronese, M, Tuosto, M, Marques, TR, Howes, O, Pascual, B, Yu, M, Masdeu, JC, Turkheimer, F, Bertoldo, A & Zanotti-Fregonara, P 2021, , Molecular Imaging and Biology, vol. 23, no. 4, pp. 560-571. https://doi.org/10.1007/s11307-020-01575-9

Tremor research group essential tremor rating scale (TETRAS): Assessing impact of different item instructions and procedures
Tremor Research Group 2020, , Tremor and Other Hyperkinetic Movements, vol. 10, 36, pp. 1-5. https://doi.org/10.5334/tohm.64

Anatomy of 18F-GE180, a failed radioligand for the TSPO protein
Zanotti-Fregonara, P, Pascual, B, Rostomily, RC, Rizzo, G, Veronese, M, Masdeu, JC & Turkheimer, F 2020, , European Journal of Nuclear Medicine and Molecular Imaging, vol. 47, no. 10, pp. 2233-2236. https://doi.org/10.1007/s00259-020-04732-y

Posterior primary progressive prosopagnosia: Structural and molecular imaging
Pascual, B, Masdeu, JC, Funk, Q, Zanotti-Fregonara, P, Shyer, M, Rockers, E & Schulz, PE 2020, , Neurology, vol. 94, no. 8, pp. 360-361. https://doi.org/10.1212/WNL.0000000000009001

Multimodal 18F-AV-1451 and MRI findings in nonfluent variant of primary progressive aphasia: Possible insights on nodal propagation of tau protein across the syntactic network
Pascual, B, Funk, Q, Zanotti-Fregonara, P, Pal, N, Rockers, E, Yu, MM, Spann, B, Román, GC, Schulz, PE, Karmonik, C, Appel, SH & Masdeu, JC 2020, , Journal of Nuclear Medicine, vol. 61, no. 2, pp. 263-269. https://doi.org/10.2967/jnumed.118.225508

Letter to the Editor re: Confirmation of Specific Binding of the 18-kDa Translocator Protein (TSPO) Radioligand [18F]GE-180: a Blocking Study Using XBD173 in Multiple Sclerosis Normal Appearing White and Grey Matter
Zanotti-Fregonara, P, Veronese, M, Rizzo, G, Pascual, B, Masdeu, JC & Turkheimer, FE 2020, , Molecular Imaging and Biology, vol. 22, no. 1, pp. 10-12. https://doi.org/10.1007/s11307-019-01433-3