Maria Belen Pascual

Maria Belen Pascual, PhD

Associate Research Professor of Neurology, Academic Institute
Associate Research Member, Research Institute
Co-Director, Neuroimaging, Nantz National Alzheimer Center
Houston Methodist
Weill Cornell Medical College


Neuroimaging Research Lab


Areas Of Expertise

Neuroimaging Neuropsychology Alzheimer's Disease Neuroinflammation Frontotemporal Degeneration Neurodegenerative Diseases Brain Functional Organization Memory Disorders Language Architecture
Publications

Recognition memory and divergent cognitive profiles in prodromal genetic frontotemporal dementia
ALLFTD consortium 2021, , Cortex, vol. 139, pp. 99-115. https://doi.org/10.1016/j.cortex.2021.03.006

Neuroinflammation is highest in areas of disease progression in semantic dementia
Pascual, B, Funk, Q, Zanotti Fregonara, P, Cykowski, MD, Veronese, M, Rockers, E, Bradbury, K, Yu, M, Nakawah, MO, Román, GC, Schulz, PE, Arumanayagam, AS, Beers, D, Faridar, A, Fujita, M, Appel, SH & Masdeu, JC 2021, , Brain, vol. 144, no. 5, pp. 1565-1575. https://doi.org/10.1093/brain/awab057

Neuroinflammation is highest in areas of disease progression in semantic dementia
Pascual, B, Funk, Q, Zanotti-Fregonara, P, Cykowski, MD, Veronese, M, Rockers, E, Bradbury, K, Yu, M, Nakawah, MO, Román, GC, Schulz, PE, Arumanayagam, AS, Beers, D, Faridar, A, Fujita, M, Appel, SH & Masdeu, JC 2021, , Brain, vol. 144, no. 5, pp. 1565-1575. https://doi.org/10.1093/brain/awab057

Parametric Mapping for TSPO PET Imaging with Spectral Analysis Impulsive Response Function
Veronese, M, Tuosto, M, Marques, TR, Howes, O, Pascual, B, Yu, M, Masdeu, JC, Turkheimer, F, Bertoldo, A & Zanotti-Fregonara, P 2021, , Molecular Imaging and Biology, vol. 23, no. 4, pp. 560-571. https://doi.org/10.1007/s11307-020-01575-9

Tremor research group essential tremor rating scale (TETRAS): Assessing impact of different item instructions and procedures
Tremor Research Group 2020, , Tremor and Other Hyperkinetic Movements, vol. 10, 36, pp. 1-5. https://doi.org/10.5334/tohm.64

Anatomy of 18F-GE180, a failed radioligand for the TSPO protein
Zanotti-Fregonara, P, Pascual, B, Rostomily, RC, Rizzo, G, Veronese, M, Masdeu, JC & Turkheimer, F 2020, , European Journal of Nuclear Medicine and Molecular Imaging, vol. 47, no. 10, pp. 2233-2236. https://doi.org/10.1007/s00259-020-04732-y

Posterior primary progressive prosopagnosia: Structural and molecular imaging
Pascual, B, Masdeu, JC, Funk, Q, Zanotti-Fregonara, P, Shyer, M, Rockers, E & Schulz, PE 2020, , Neurology, vol. 94, no. 8, pp. 360-361. https://doi.org/10.1212/WNL.0000000000009001

Multimodal 18F-AV-1451 and MRI findings in nonfluent variant of primary progressive aphasia: Possible insights on nodal propagation of tau protein across the syntactic network
Pascual, B, Funk, Q, Zanotti-Fregonara, P, Pal, N, Rockers, E, Yu, MM, Spann, B, Román, GC, Schulz, PE, Karmonik, C, Appel, SH & Masdeu, JC 2020, , Journal of Nuclear Medicine, vol. 61, no. 2, pp. 263-269. https://doi.org/10.2967/jnumed.118.225508

Letter to the Editor re: Confirmation of Specific Binding of the 18-kDa Translocator Protein (TSPO) Radioligand [18F]GE-180: a Blocking Study Using XBD173 in Multiple Sclerosis Normal Appearing White and Grey Matter
Zanotti-Fregonara, P, Veronese, M, Rizzo, G, Pascual, B, Masdeu, JC & Turkheimer, FE 2020, , Molecular Imaging and Biology, vol. 22, no. 1, pp. 10-12. https://doi.org/10.1007/s11307-019-01433-3

Restoring regulatory T-cell dysfunction in Alzheimer's disease through ex vivo expansion
Faridar, A, Thome, AD, Zhao, W, Thonhoff, JR, Beers, DR, Pascual, B, Masdeu, JC & Appel, SH 2020, , Brain communications, vol. 2, no. 2, pp. fcaa112. https://doi.org/10.1093/braincomms/fcaa112

Head-to-head comparison of 11C-PBR28 and 11C-ER176 for quantification of the translocator protein in the human brain
Zanotti-Fregonara, P, Pascual, B, Veronese, M, Yu, M, Beers, D, Appel, SH & Masdeu, JC 2019, , European Journal of Nuclear Medicine and Molecular Imaging, vol. 46, no. 9, pp. 1822-1829. https://doi.org/10.1007/s00259-019-04349-w

The validity of 18 F-GE180 as a TSPO imaging agent
Zanotti-Fregonara, P, Veronese, M, Pascual, B, Rostomily, RC, Turkheimer, F & Masdeu, JC 2019, , European Journal of Nuclear Medicine and Molecular Imaging, vol. 46, no. 6, pp. 1205-1207. https://doi.org/10.1007/s00259-019-4268-4

“Ears of the lynx” MRI sign is associated with SPG11 and SPG15 hereditary spastic paraplegia
Pascual, MB, De Bot, ST, Daniels, MR, França, MC, Toro, C, Riverol, M, Hedera, P, Bassi, MT, Bresolin, N, Van De Warrenburg, BP, Kremer, B, Nicolai, J, Charles, P, Xu, J, Singh, S, Patronas, NJ, Fung, SH, Gregory, MD & Masdeu, JC 2019, , American Journal of Neuroradiology, vol. 40, no. 1, pp. 199-203. https://doi.org/10.3174/ajnr.A5935

Functional alterations of myeloid cells during the course of Alzheimer's disease
Thome, AD, Faridar, A, Beers, DR, Thonhoff, JR, Zhao, W, Wen, S, Pascual, B, Masdeu, JC & Appel, SH 2018, , Molecular Neurodegeneration, vol. 13, no. 1, pp. 61. https://doi.org/10.1186/s13024-018-0293-1

Conversion of L-dopa to Extended Release L-dopa (Rytary®) in Patients with Fluctuating Parkinson's Disease: Predictor's of Dose
Ondo, WG, Coss, P, Christie, M & Pascual, MB 2019, , Journal of Parkinsons disease, vol. 9, no. 1, pp. 153-156. https://doi.org/10.3233/JPD-181427

Head-to-head comparison of 11C-PBR28 and 18F-GE180 for quantification of the translocator protein in the human brain
Zanotti-Fregonara, P, Pascual, B, Rizzo, G, Yu, M, Pal, N, Beers, D, Carter, R, Appel, SH, Atassi, N & Masdeu, JC 2018, , Journal of Nuclear Medicine, vol. 59, no. 8, pp. 1260-1266. https://doi.org/10.2967/jnumed.117.203109

A biomarker combining imaging and neuropsychological assessment for tracking early Alzheimer’s disease in clinical trials
Alzheimers Disease Neuroimaging Initiative 2018, , Current Alzheimer Research, vol. 15, no. 5, pp. 429-442. https://doi.org/10.2174/1567205014666171106150309

Hypothalamic relapse of a cardiac large B-cell lymphoma presenting with memory loss, confabulation, alexia-agraphia, apathy, hypersomnia, appetite disturbances and diabetes insipidus
Ospina-Garciá, N, Román, GC, Pascual, B, Schwartz, MR & Preti, HA 2018, , BMJ Case Reports, vol. 2018, 217700. https://doi.org/10.1136/bcr-2016-217700

Tau, amyloid, and hypometabolism in the logopenic variant of primary progressive aphasia
Pascual, B & Masdeu, JC 2016, , Neurology, vol. 86, no. 5, pp. 487-8. https://doi.org/10.1212/WNL.0000000000002340

Genetic and degenerative disorders primarily causing dementia
Masdeu, JC & Pascual, B 2016, . in Handbook of Clinical Neurology. vol. 135, Elsevier, pp. 525-64. https://doi.org/10.1016/B978-0-444-53485-9.00026-X