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Maria Belen Pascual, PhD

Associate Research Professor of Neurology, Academic Institute
Associate Research Member, Research Institute
Co-Director, Neuroimaging, Nantz National Alzheimer Center
Houston Methodist
Weill Cornell Medical College


Research Lab


Publications

Posterior primary progressive prosopagnosia: Structural and molecular imaging
Pascual, B, Masdeu, JC, Funk, Q, Zanotti-Fregonara, P, Shyer, M, Rockers, E & Schulz, PE 2020, Neurology, vol. 94, no. 8, pp. 360-361. https://doi.org/10.1212/WNL.0000000000009001

Multimodal 18F-AV-1451 and MRI findings in nonfluent variant of primary progressive aphasia: Possible insights on nodal propagation of tau protein across the syntactic network
Pascual, B, Funk, Q, Zanotti-Fregonara, P, Pal, N, Rockers, E, Yu, MM, Spann, B, Román, GC, Schulz, PE, Karmonik, C, Appel, SH & Masdeu, JC 2020, Journal of Nuclear Medicine, vol. 61, no. 2, pp. 263-269. https://doi.org/10.2967/jnumed.118.225508

Anatomy of 18F-GE180, a failed radioligand for the TSPO protein
Zanotti-Fregonara, P, Pascual, B, Rostomily, RC, Rizzo, G, Veronese, M, Masdeu, JC & Turkheimer, F 2020, European Journal of Nuclear Medicine and Molecular Imaging. https://doi.org/10.1007/s00259-020-04732-y

Head-to-head comparison of 11C-PBR28 and 11C-ER176 for quantification of the translocator protein in the human brain
Zanotti Fregonara, P, Pascual, MB, Veronese, M, Yu, MM, Beers, D, Appel, SH & Masdeu, JC 2019, European Journal of Nuclear Medicine and Molecular Imaging, vol. 46, no. 9, pp. 1822-1829. https://doi.org/10.1007/s00259-019-04349-w

Letter to the Editor re: Confirmation of Specific Binding of the 18-kDa Translocator Protein (TSPO) Radioligand [18F]GE-180: a Blocking Study Using XBD173 in Multiple Sclerosis Normal Appearing White and Grey Matter
Zanotti Fregonara, P, Veronese, M, Rizzo, G, Pascual, MB, Masdeu, JC & Turkheimer, FE 2019, Molecular Imaging and Biology. https://doi.org/10.1007/s11307-019-01433-3

The validity of 18F-GE180 as a TSPO imaging agent
Zanotti Fregonara, P, Veronese, M, Pascual, MB, Rostomily, RC, Turkheimer, F & Masdeu, JC 2019, European Journal of Nuclear Medicine and Molecular Imaging. https://doi.org/10.1007/s00259-019-4268-4

“Ears of the lynx” MRI sign is associated with SPG11 and SPG15 hereditary spastic paraplegia
Pascual, MB, De Bot, ST, Daniels, MR, França, MC, Toro, C, Riverol, M, Hedera, P, Bassi, MT, Bresolin, N, Van De Warrenburg, BP, Kremer, B, Nicolai, J, Charles, P, Xu, J, Singh, S, Patronas, NJ, Fung, SH, Gregory, MD & Masdeu, JC 2019, American Journal of Neuroradiology, vol. 40, no. 1, pp. 199-203. https://doi.org/10.3174/ajnr.A5935

Functional alterations of myeloid cells during the course of Alzheimer's disease
Thome, AD, Faridar, A, Beers, DR, Thonhoff, JR, Zhao, W, Wen, S, Pascual, B, Masdeu, JC & Appel, SH 2018, Molecular Neurodegeneration, vol. 13, no. 1, pp. 61. https://doi.org/10.1186/s13024-018-0293-1

Head-to-head comparison of 11C-PBR28 and 18F-GE180 for quantification of the translocator protein in the human brain
Zanotti Fregonara, P, Pascual, MB, Rizzo, G, Yu, MM, Pal, N, Beers, D, Carter, R, Appel, SH, Atassi, N & Masdeu, JC 2018, Journal of Nuclear Medicine, vol. 59, no. 8, pp. 1260-1266. https://doi.org/10.2967/jnumed.117.203109

Hypothalamic relapse of a cardiac large B-cell lymphoma presenting with memory loss, confabulation, alexia-agraphia, apathy, hypersomnia, appetite disturbances and diabetes insipidus
Ospina-Garciá, N, Roman, GC, Pascual, MB, Schwartz, MR & Preti, HA 2018, BMJ case reports, vol. 2018, 217700. https://doi.org/10.1136/bcr-2016-217700

A biomarker combining imaging and neuropsychological assessment for tracking early Alzheimer’s disease in clinical trials
Alzheimers Disease Neuroimaging Initiative 2018, Current Alzheimer Research, vol. 15, no. 5, pp. 429-442. https://doi.org/10.2174/1567205014666171106150309

Tau, amyloid, and hypometabolism in the logopenic variant of primary progressive aphasia
Pascual, B & Masdeu, JC 2016, Neurology, vol. 86, no. 5, pp. 487-8. https://doi.org/10.1212/WNL.0000000000002340

Genetic and degenerative disorders primarily causing dementia
Masdeu, JC & Pascual, B 2016, . in Handbook of Clinical Neurology. vol. 135, Elsevier, pp. 525-64. https://doi.org/10.1016/B978-0-444-53485-9.00026-X

Quantitative analysis of 3D T1-weighted gadolinium (Gd) DCE-MRI with different repetition times
Rockers, ED, Pascual, MB, Bajaj, S, Masdeu, JC & Xue, Z 2016, . in H Liao, G Zheng, S-L Lee, P Cattin & P Jannin (eds), Medical Imaging and Augmented Reality - 7th International Conference, MIAR 2016, Proceedings. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), vol. 9805 LNCS, Springer-Verlag, pp. 259-268, 7th International Conference on Medical Imaging and Augmented Reality, MIAR 2016, Bern, Switzerland, 8/24/16. https://doi.org/10.1007/978-3-319-43775-0_23

New scoring methodology improves the sensitivity of the Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS-Cog) in clinical trials
Verma, N, Beretvas, SN, Pascual, B, Masdeu, JC, Markey, MK & Alzheimer’s Disease Neuroimaging Initiative 2015, Alzheimers Research and Therapy, vol. 7, no. 1, pp. 64. https://doi.org/10.1186/s13195-015-0151-0

Large-scale brain networks of the human left temporal pole: A functional connectivity MRI study
Pascual, MB, Masdeu, JC, Hollenbeck, M, Makris, N, Insausti, R, Ding, SL & Dickerson, BC 2015, Cerebral Cortex, vol. 25, no. 3, pp. 680-702. https://doi.org/10.1093/cercor/bht260

Contribution of Neuroimaging to the Diagnosis of Alzheimer's Disease and Vascular Dementia
Roman, GC & Pascual, MB 2012, Archives of Medical Research, vol. 43, no. 8, pp. 671-676. https://doi.org/10.1016/j.arcmed.2012.10.018

Decreased carbon-11-flumazenil binding in early Alzheimer's disease
Pascual, B, Prieto, E, Arbizu, J, Marti-Climent, JM, Peñuelas, I, Quincoces, G, Zarauza, R, Pappatà, S & Masdeu, JC 2012, Brain, vol. 135, no. 9, pp. 2817-2825. https://doi.org/10.1093/brain/aws210

Age-Related changes in the thickness of cortical zones in humans
McGinnis, SM, Brickhouse, M, Pascual, MB & Dickerson, BC 2011, Brain Topography, vol. 24, no. 3-4, pp. 279-291. https://doi.org/10.1007/s10548-011-0198-6

Brain glucose metabolism in vascular white matter disease with dementia: Differentiation from Alzheimer disease
Pascual, MB, Prieto, E, Arbizu, J, Marti-Climent, J, Olier, J & Masdeu, JC 2010, Stroke, vol. 41, no. 12, pp. 2889-2893. https://doi.org/10.1161/STROKEAHA.110.591552

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