Lawrence Rice, MD

Dottie and Jimmy C. Adair Distinguished Chair in Hematology, Department of Medicine
Professor of Medicine, Academic Institute
Full Clinical Member, Research Institute
Houston Methodist
Weill Cornell Medical College


After completing an Internal Medicine Internship, Residency, and Hematology fellowship at Baylor College of Medicine, Dr. Rice was appointed to the faculty and became a Professor of Medicine and Professor of Thrombosis Research. For more than 20 years, he served as the Hematology Program Director and Director of the required medical student Hematology/Oncology course.

In 2007, his primary affiliation changed to Chief of Hematology at Houston Methodist Hospital and Professor of Medicine at Weill Cornell Medical College. He has maintained an active Consultative Hematology practice at Houston Methodist for more than 30 years. This program is distinguished by the depth and breadth of the blood disorders managed, including Congenital TTP, paroxysmal nocturnal hemoglobinuria and Evans' syndrome. Two-thirds of his patients have "benign" hematologic disorders and one-third have hematologic malignancies.

Dr. Rice actively teaches medical students, residents and subspecialty fellows, and has received numerous teaching awards, including induction in the inaugural class of the Baylor Medicine Educator Hall of Fame. In 2009-2010, he received the Edward C. Lynch Outstanding Teacher Award from Houston Methodist Internal Medicine residents, the Houston Methodist GME Teacher of the Year Award, the Hematology Honorary Fellow (Outstanding Teacher) Award from graduating MD Anderson Hematology/Oncology fellows, and the Hematology Educator of the Year from Baylor Hematology/Oncology fellows. Dr. Rice frequently gives lectures and chairs national educational symposia and CME events.

Description of Research

Dr. Rice's research interests include:

-Thrombocytopenic disorders (ITP, TTP and HIT)
-Bleeding, clotting and anticoagulation problems
-Anemias, erythropoietin actions and iron metabolism
Recent clinical studies include participation in pivotal trials of novel platelet-stimulating hormones, anticoagulants, and iron-chelators.

Areas Of Expertise

Hematology Anemias Thrombocytopenias Anticoagulants Erythropoietin
Education & Training

Residency, Baylor College of Medicine
Clinical Fellowship, Baylor College of Medicine
MD, Emory University

Interpreting coagulation mixing study results in the era of direct oral anticoagulants
Kim, MJ, Salazar, E, Philips, B, Rice, L, Castillo, B, Leveque, C & Chen, J 2024, , Blood Coagulation and Fibrinolysis, vol. 35, no. 1, pp. 23-26.

Long-term outcomes in patients with Burkitt lymphoma older than 65 years: an analysis of the Texas Cancer Registry
Burns, EA, Wilson, JJ, Mathur, S, Kieser, R, Gong, Z, Hu, CCA, Tang, CHA, Petkova, J, Yuen, C, Mai, H, Shah, S, Rice, L, Ganguly, S & Pingali, SR 2023, , Annals of Hematology, vol. 102, no. 10, pp. 2753-2763.

Survival After Ruptured Spontaneous Hepatic Subcapsular Hematoma Following Heparin Initiation for Submassive Pulmonary Embolism
Zhang, Y, Raj, R, Hobeika, M, Rahimi, M, Rice, L & Awar, M 2022, , Annals of Internal Medicine Clinical Cases, vol. 1, no. 10, e220907.

Neutrophil production and kinetics: Neutropenia and neutrophilia
Rice, L & Salazar, E 2022, . in Rossis Principles of Transfusion Medicine. Wiley, pp. 188-193.

Recurrent Gastrointestinal Bleeding in a Middle-Aged Man
Gowani, F, Phillips, B, Leveque, C, Castillo, B, Chen, J, Chandler, W, Rice, L & Salazar, E 2022, , Lab Medicine, vol. 53, no. 4, pp. E91-E94.

Sickle cell hepatopathy with spur cell anemia
Rice, L & Schwartz, MR 2021, , Blood, vol. 138, no. 3, pp. 283.

Antiplatelet and anticoagulant agents
Ibrahim, IF & Rice, L 2021, . in Management of Bleeding Patients. Springer International Publishing, pp. 289-301.

Neocytolysis on descending the mountain and ascending into space
Rice, L & Gunga, HC 2021, , Acta Physiologica, vol. 232, no. 3, e13676.

Mycobacterial Infections With Ruxolitinib: A Retrospective Pharmacovigilance Review
Anand, K, Burns, EA, Ensor, J, Rice, L & Pingali, SR 2020, , Clinical Lymphoma, Myeloma and Leukemia, vol. 20, no. 1, pp. 18-23.

Reactive NK cell lymphocytosis with atypical immunophenotype in a chronic HIV-infected patient
Liu, S, Rice, L & Ewton, A 2021, , Cytometry Part B - Clinical Cytometry, vol. 100, no. 2, pp. 240-242.

The risk of major bleeding in patients with suspected heparin-induced thrombocytopenia
Pishko, AM, Lefler, DS, Gimotty, P, Paydary, K, Fardin, S, Arepally, GM, Crowther, M, Rice, L, Vega, R, Cines, DB, Guevara, JP & Cuker, A 2019, , Journal of Thrombosis and Haemostasis, vol. 17, no. 11, pp. 1956-1965.

Delayed autologous stem cell transplantation following cardiac transplantation experience in patients with cardiac amyloidosis
Trachtenberg, BH, Kamble, RT, Rice, L, Araujo-Gutierrez, R, Bhimaraj, A, Guha, A, Park, MH, Hussain, I, Bruckner, BA, Suarez, EE, Victor, III, DW, Adrogue, HE, Baker, KR & Estep, JD 2019, , American Journal of Transplantation, vol. 19, no. 10, pp. 2900-2909.

Acute myeloid leukaemia presenting as acute liver failure-a case report and literature review
Sun, K, Reynolds, RJ, Sheu, TG, Tomsula, JA, Colton, L & Rice, L 2019, , ecancermedicalscience, vol. 13, 960.

Prospective comparison of the HEP score and 4Ts score for the diagnosis of heparin-induced thrombocytopenia
Pishko, AM, Fardin, S, Lefler, DS, Paydary, K, Vega, R, Arepally, GM, Crowther, M, Rice, L, Cines, DB & Cuker, A 2018, , Blood Advances, vol. 2, no. 22, pp. 3155-3162.

HITs and misses in 100 years of heparin
Rice, L 2017, , Hematology, vol. 2017, no. 1, pp. 667-673.

Recombinant ADAMTS-13: First-in-human pharmacokinetics and safety in congenital thrombotic thrombocytopenic purpura
Scully, M, Knöbl, P, Kentouche, K, Rice, L, Windyga, J, Schneppenheim, R, Kremer Hovinga, JA, Kajiwara, M, Fujimura, Y, Maggiore, C, Doralt, J, Hibbard, C, Martell, L & Ewenstein, B 2017, , Blood, vol. 130, no. 19, pp. 2055-2063.

Intravenous Immunoglobulin for Heparin-Induced Thrombocytopenia
Ibrahim, IF & Rice, L 2017, , CHEST, vol. 152, no. 4, pp. 906-907.

Neutrophilic Leukocytosis, Neutropenia, Monocytosis, and Monocytopenia
Rice, L & Jung, M 2017, . in Hematology: Basic Principles and Practice. Elsevier, pp. 675-681.

Leukapheresis reduces 4-week mortality in acute myeloid leukemia patients with hyperleukocytosis–a retrospective study from a tertiary center
Nan, X, Qin, Q, Gentille, C, Ensor, J, Leveque, C, Pingali, R, Phan, AT, Rice, L & Iyer, S 2017, , Leukemia and Lymphoma, vol. 58, no. 9, pp. 2110-2117.

Neutrophilic Leukocytosis, Neutropenia, Monocytosis, and Monocytopenia
Rice, L & Jung, M 2017, . in Hematology: Basic Principles and Practice. Elsevier, pp. 675-681.