Dr. Kristopher Brannan is an Assistant Professor and CPRIT Scholar in the Center for RNA Therapeutics and Houston Methodist Cancer Center at the Houston Methodist Research Institute. He received his B.A. degree in molecular, cellular and developmental biology at the University of Colorado Boulder, and his Ph.D. in molecular biology at the University of Colorado School of Medicine. He was a postdoctoral fellow at the University of California San Diego and joined the faculty at the Houston Methodist Research Institute in 2021. His work is focused on RNA-protein interactions that regulate gene expression programs disrupted in cancer and neurological disease.
We utilize innovative molecular and computational approaches to:
-Explore the functional RNA binding activity of the nucleocytoplasmic transport (NCT) machinery disrupted in neurodegeneration.
-Map the RNA-protein interaction networks that drive breast cancer progression and plasticity.
-Evaluate RNA-based therapeutics in cell-line models, animal models, and patient tissues.