Kristopher W. Brannan

Kristopher W. Brannan, PhD

Assistant Professor of Cardiovascular Sciences, Academic Institute
Assistant Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Brannan Lab


kwbrannan@houstonmethodist.org
Publications

Directed editing of cellular RNA via nuclear delivery of CRISPR/CAS9
Brannan, KW, Yeo, GW, Marina, RJ & Nelles, D Sep. 27 2022, , Patent No. 11453891. <https://patents.justia.com/patent/11453891>

Robust single-cell discovery of RNA targets of RNA-binding proteins and ribosomes
Brannan, KW, Chaim, IA, Marina, RJ, Yee, BA, Kofman, ER, Lorenz, DA, Jagannatha, P, Dong, KD, Madrigal, AA, Underwood, JG & Yeo, GW 2021, , Nature Methods, vol. 18, no. 5, pp. 507-519. https://doi.org/10.1038/s41592-021-01128-0

Evaluation of Engineered CRISPR-Cas-Mediated Systems for Site-Specific RNA Editing
Marina, RJ, Brannan, KW, Dong, KD, Yee, BA & Yeo, GW 2020, , Cell Reports, vol. 33, no. 5, 108350. https://doi.org/10.1016/j.celrep.2020.108350

Control of RNA Pol II Speed by PNUTS-PP1 and Spt5 Dephosphorylation Facilitates Termination by a “Sitting Duck Torpedo” Mechanism
Cortazar, MA, Sheridan, RM, Erickson, B, Fong, N, Glover-Cutter, K, Brannan, K & Bentley, DL 2019, , Molecular Cell, vol. 76, no. 6, pp. 896-908.e4. https://doi.org/10.1016/j.molcel.2019.09.031

From Protein-RNA Predictions toward a Peptide-RNA Code
Brannan, KW & Yeo, GW 2016, , Molecular Cell, vol. 64, no. 3, pp. 437-438. https://doi.org/10.1016/j.molcel.2016.10.023

SONAR Discovers RNA-Binding Proteins from Analysis of Large-Scale Protein-Protein Interactomes
Brannan, KW, Jin, W, Huelga, SC, Banks, CAS, Gilmore, JM, Florens, L, Washburn, MP, Van Nostrand, EL, Pratt, GA, Schwinn, MK, Daniels, DL & Yeo, GW 2016, , Molecular Cell, vol. 64, no. 2, pp. 282-293. https://doi.org/10.1016/j.molcel.2016.09.003

Effects of Transcription Elongation Rate and Xrn2 Exonuclease Activity on RNA Polymerase II Termination Suggest Widespread Kinetic Competition
Fong, N, Brannan, K, Erickson, B, Kim, H, Cortazar, MA, Sheridan, RM, Nguyen, T, Karp, S & Bentley, DL 2015, , Molecular Cell, vol. 60, no. 2, pp. 256-267. https://doi.org/10.1016/j.molcel.2015.09.026

MRNA Decapping Factors and the Exonuclease Xrn2 Function in Widespread Premature Termination of RNA Polymerase II Transcription
Brannan, K, Kim, H, Erickson, B, Glover-Cutter, K, Kim, S, Fong, N, Kiemele, L, Hansen, K, Davis, R, Lykke-Andersen, J & Bentley, DL 2012, , Molecular Cell, vol. 46, no. 3, pp. 311-324. https://doi.org/10.1016/j.molcel.2012.03.006