Khurram Nasir, MD, MPH

Co-director, Center for Outcomes Research
Houston Methodist


Dr. Nasir received his MD from Pakistan, followed by a MPH at John Hopkins University. Dr. Nasir completed his internal medicine residency at Boston Medical Center and cardiology fellowship at Yale University. He also received postdoctoral research training at the division of cardiology at Johns Hopkins Hospital and was recipient of NIH T-32 fellowship in cardiac imaging at Massachusetts General Hospital. He recently earned a Master’s degree in Health Economics and Policy Management from London School of Economics & Political Science.

Dr. Nasir serves as Associate Editor for Circulation: Quality of Care and Outcomes, editorial board member for Circulation as well on the board of directors for American Society of Preventive Cardiology (ASPC). He was honored with the Johns Hopkins Distinguished Alumnus Award in 2013, which acknowledges alumni who have typified Johns Hopkins tradition of excellence and brought credit to the University by their personal accomplishments, professional achievements, or humanitarian service

Dr. Nasir has over 500 peer-reviewed articles which are published in top journals such as Lancet, New England Journal of Medicine, JAMA, Archives of Internal Medicine, Circulation, Journal of American College of Cardiology and European Heart Journal. Dr. Nasir has lectured extensively throughout the world on coronary arthrosclerosis, cardiac imaging and prevention.

Description of Research

Dr. Nasir’s area of expertise in preventive cardiology involves the identification of high-risk individuals — those likely to have a heart attack or stroke. His research helps to identify the at-risk population so that treatments may be targeted to them.


Association of particles of lipoprotein subclasses with arterial stiffness in a high-risk working population: the Baptist Employee Healthy Heart Study (BEHHS)
Aziz, M, Gannarapu, S, Humayun, C, Siddiqui, U, Nasir, K & Aneni, EC 2020, Egyptian Heart Journal, vol. 72, no. 1, 12.

Prevalence, Trends, and Distribution of Nicotine and Marijuana use in E-cigarettes among US adults: The Behavioral Risk Factor Surveillance System 2016–2018
Uddin, SMI, Osei, AD, Obisesan, OH, El-Shahawy, O, Dzaye, O, Cainzos-Achirica, M, Mirbolouk, M, Orimoloye, OA, Stokes, A, Benjamin, EJ, Bhatnagar, A, DeFilippis, AP, Henry, TS, Nasir, K & Blaha, MJ 2020, Preventive Medicine, vol. 139, 106175.

Role of Coronary Artery and Thoracic Aortic Calcium as Risk Modifiers to Guide Antihypertensive Therapy in Stage 1 Hypertension (From the Multiethnic Study of Atherosclerosis)
Elshazly, MB, Abdellatif, A, Dargham, SR, Rifai, MA, Quispe, R, Cainzos Achirica, M, Martin, SS, Yeboah, J, Psaty, BM, Post, WS, Nasir, K, Budoff, MJ, Blumenthal, RS, Blaha, MJ & McEvoy, JW 2020, American Journal of Cardiology, vol. 126, pp. 45-55.

The relationship between cardiorespiratory fitness, cardiovascular risk factors and atherosclerosis
Chu, DJ, Al Rifai, M, Virani, SS, Brawner, CA, Nasir, K & Al-Mallah, M 2020, Atherosclerosis, vol. 304, pp. 44-52.

Recovery of Left Ventricular Systolic Function and Clinical Outcomes in Young Adults With Myocardial Infarction
Wu, WY, Biery, DW, Singh, A, Divakaran, S, Berman, AN, Ayuba, G, DeFilippis, EM, Nasir, K, Januzzi, JL, Di Carli, MF, Bhatt, DL & Blankstein, R 2020, Journal of the American College of Cardiology, vol. 75, no. 22, pp. 2804-2815.

Underuse of statins for secondary prevention of atherosclerotic cardiovascular disease events among ambulatory surgical patients
Schonberger, RB, Vallurupalli, V, Matlin, H, Blitz, D, Nwozuzu, A, Barron, B, Zhang, Y, Dai, F, Jacoby, D, Nasir, K & Bardia, A 2020, Preventive Medicine Reports, vol. 18, 101085.

Cumulative Burden of Financial Hardship From Medical Bills Across the Spectrum of Diabetes Mellitus and Atherosclerotic Cardiovascular Disease Among Non-Elderly Adults in the United States
Mszar, R, Grandhi, GR, Valero-Elizondo, J, Caraballo, C, Khera, R, Desai, N, Virani, SS, Blankstein, R, Blaha, MJ & Nasir, K 2020, Journal of the American Heart Association, vol. 9, no. 10, pp. e015523.

Rural-Urban Differences in Cardiovascular Mortality in the US, 1999-2017
Cross, SH, Mehra, MR, Bhatt, DL, Nasir, K, ODonnell, CJ, Califf, RM & Warraich, HJ 2020, JAMA - Journal of the American Medical Association, vol. 323, no. 18, pp. 1852-1854.

Facility-level variation in cardiac stress test use among patients with diabetes: Findings from the Veterans Affairs National Database
Mahtta, D, Ahmed, ST, Shah, NR, Ramsey, DJ, Akeroyd, JM, Nasir, K, Hamzeh, IR, Elgendy, IY, Waldo, SW, Al-Mallah, M, Jneid, H, Ballantyne, CM, Petersen, LA & Virani, SS 2020, Diabetes care, vol. 43, no. 5, pp. E58-E60.

Risk Factors and Outcomes of Very Young Adults Who Experience Myocardial Infarction: The Partners YOUNG-MI Registry
Yang, J, Biery, DW, Singh, A, Divakaran, S, DeFilippis, EM, Wu, WY, Klein, J, Hainer, J, Ramsis, M, Natarajan, P, Januzzi, JL, Nasir, K, Bhatt, DL, Di Carli, MF & Blankstein, R 2020, American Journal of Medicine, vol. 133, no. 5, pp. 605-612.e1.

Power of zero stronger than “soft” plaque
Budoff, MJ, Blankstein, R, Nasir, K & Blaha, MJ 2020, Journal of cardiovascular computed tomography, vol. 14, no. 3.

Predictors of coronary artery calcium among 20-30-year-olds: The Coronary Artery Calcium Consortium
Osei, AD, Uddin, SMI, Dzaye, O, Cainzos Achirica, M, Dardari, ZA, Obisesan, OH, Kianoush, S, Mirbolouk, M, Orimoloye, OA, Shaw, L, Rumberger, JA, Berman, D, Rozanski, A, Miedema, MD, Budoff, MJ, Vasan, RS, Nasir, K & Blaha, MJ 2020, Atherosclerosis, vol. 301, pp. 65-68.

Interplay of Coronary Artery Calcium and Risk Factors for Predicting CVD/CHD Mortality: The CAC Consortium
Grandhi, GR, Mirbolouk, M, Dardari, ZA, Al-Mallah, M, Rumberger, JA, Shaw, LJ, Blankstein, R, Miedema, MD, Berman, DS, Budoff, MJ, Krumholz, HM, Blaha, MJ & Nasir, K 2020, JACC: Cardiovascular Imaging, vol. 13, no. 5, pp. 1175-1186.

Coronary Artery Calcium as a Synergistic Tool for the Age- and Sex-Specific Risk of Cardiovascular and Cancer Mortality: The Coronary Artery Calcium Consortium
Dzaye, O, Al Rifai, M, Dardari, Z, Shaw, LJ, Al-Mallah, M, Handy Marshall, C, Rozanski, A, Mortensen, MB, Duebgen, M, Matsushita, K, Rumberger, JA, Berman, DS, Budoff, MJ, Miedema, MD, Nasir, K, Blaha, MJ & Whelton, SP 2020, Journal of the American Heart Association, vol. 9, no. 8, pp. e015306.

Incidence of New Coronary Calcification: Time to Conversion From CAC = 0
Dzaye, O, Dardari, ZA, Cainzos Achirica, M, Blankstein, R, Szklo, M, Budoff, MJ, Lima, JAC, Blumenthal, RS, Nasir, K & Blaha, MJ 2020, Journal of the American College of Cardiology, vol. 75, no. 13, pp. 1610-1613.

Leveraging the Electronic Health Records for Population Health: A Case Study of Patients With Markedly Elevated Blood Pressure
Lu, Y, Huang, C, Mahajan, S, Schulz, WL, Nasir, K, Spatz, ES & Krumholz, HM 2020, Journal of the American Heart Association, vol. 9, no. 7, pp. e015033.

Absence of Coronary Artery Calcification in Middle-Aged Familial Hypercholesterolemia Patients Without Atherosclerotic Cardiovascular Disease
Mszar, R, Grandhi, GR, Valero-Elizondo, J, Virani, SS, Blankstein, R, Blaha, M, Mata, P, Miname, MH, Al Rasadi, K, Krumholz, HM, Santos, RD & Nasir, K 2020, JACC. Cardiovascular imaging, vol. 13, no. 4, pp. 1090-1092.

Coronary Artery Calcification, Statin Use and Long-Term Risk of Atherosclerotic Cardiovascular Disease Events (from the Multi-Ethnic Study of Atherosclerosis)
Rifai, MA, Blaha, MJ, Patel, J, Xiaoming, J, Cainzos-Achirica, M, Greenland, P, Budoff, M, Yeboah, J, Nasir, K, Al-Mallah, M & Virani, SS 2020, American Journal of Cardiology, vol. 125, no. 6, pp. 835-839.

Cardiovascular Mortality After Type 1 and Type 2 Myocardial Infarction in Young Adults
Singh, A, Gupta, A, DeFilippis, EM, Qamar, A, Biery, DW, Almarzooq, Z, Collins, B, Fatima, A, Jackson, C, Galazka, P, Ramsis, M, Pipilas, DC, Divakaran, S, Cawley, M, Hainer, J, Klein, J, Jarolim, P, Nasir, K, Januzzi, JL, Di Carli, MF, Bhatt, DL & Blankstein, R 2020, Journal of the American College of Cardiology, vol. 75, no. 9, pp. 1003-1013.

Association between frequency of primary care provider visits and evidence-based statin prescribing and statin adherence: Findings from the Veterans Affairs system
Ahmed, ST, Mahtta, D, Rehman, H, Akeroyd, J, Al Rifai, M, Rodriguez, F, Jneid, H, Nasir, K, Samad, Z, Alam, M, Petersen, LA & Virani, SS 2020, American Heart Journal, vol. 221, pp. 9-18.

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