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Junhua Mai, PhD

Assistant Research Professor of Nanomedicine, Academic Institute
Assistant Research Member, Research Institute
Houston Methodist
Weill Cornell Medical College


jmai@houstonmethodist.org
Publications

Injectable Porous Silicon Nanoparticles as a Plasma Cytokine Scavenger for Potentiating Cytokine Storm Syndrome Treatment
Qi, R, Li, S, Li, F, Mai, J, Wang, Y, Zhu, G, Zhang, D, Li, Z, Shen, H, Shen, J & Liu, X 2023, , Advanced NanoBiomed Research, vol. 3, no. 10, 2300037. https://doi.org/10.1002/anbr.202300037

An mRNA vaccine elicits STING-dependent antitumor immune responses
Chen, Z, Meng, C, Mai, J, Liu, Y, Li, H & Shen, H 2023, , Acta Pharmaceutica Sinica B, vol. 13, no. 3, pp. 1274-1286. https://doi.org/10.1016/j.apsb.2022.11.013

Corrigendum to "PTGER3 induces ovary tumorigenesis and confers resistance to cisplatin therapy through up-regulation Ras-MAPK/Erk-ETS1-ELK1/CFTR1 axis" [EBioMedicine 40 (2019) 290-304]
Rodriguez-Aguayo, C, Bayraktar, E, Ivan, C, Aslan, B, Mai, J, He, G, Mangala, LS, Jiang, D, Nagaraja, AS, Ozpolat, B, Chavez-Reyes, A, Ferrari, M, Mitra, R, Siddik, ZH, Shen, H, Yang, X, Sood, AK & Lopez-Berestein, G 2022, , EBioMedicine, vol. 83, 104194, pp. 104194. https://doi.org/10.1016/j.ebiom.2022.104194

Identification of an Aptamer With Binding Specificity to Tumor-Homing Myeloid-Derived Suppressor Cells
Tian, S, Welte, T, Mai, J, Liu, Y, Ramirez, M & Shen, H 2022, , Frontiers in Pharmacology, vol. 12, 752934, pp. 752934. https://doi.org/10.3389/fphar.2021.752934

Antitumor Immunity from Abdominal Flap-Embedded Therapeutic Cancer Vaccine
Liu, X, Mai, J, Meng, C, Spiegel, AJ, Wei, W & Shen, H 2022, , International Journal of Nanomedicine, vol. 17, pp. 203-212. https://doi.org/10.2147/IJN.S341394

A modified porous silicon microparticle potentiates protective systemic and mucosal immunity for SARS-CoV-2 subunit vaccine
Adam, A, Shi, Q, Wang, B, Zou, J, Mai, J, Osman, SR, Wu, W, Xie, X, Aguilar, PV, Bao, X, Shi, PY, Shen, H & Wang, T 2022, , Translational Research, vol. 249, pp. 13-27. https://doi.org/10.1016/j.trsl.2022.06.004

The Sympathetic Nervous System Modulates Cancer Vaccine Activity through Monocyte-Derived Cells
Hinkle, L, Liu, Y, Meng, C, Chen, Z, Mai, J, Zhang, L, Xu, Y, Pan, PY, Chen, SH & Shen, H 2021, , Journal of Immunology, vol. 207, no. 12, pp. 3131-3140. https://doi.org/10.4049/jimmunol.2100719

Rad51 Silencing with siRNA Delivered by Porous Silicon-Based Microparticle Enhances the Anti-Cancer Effect of Doxorubicin in Triple-Negative Breast Cancer
Wu, Z, Zhu, L, Mai, J, Shen, H & Xu, R 2021, , Journal of Biomedical Nanotechnology, vol. 17, no. 12, pp. 2351-2363. https://doi.org/10.1166/jbn.2021.3198

A heparan-sulfate-bearing syndecan-1 glycoform is a distinct surface marker for intra-tumoral myeloid-derived suppressor cells
Welte, T, Mai, J, Zhang, Z, Tian, S, Zhang, G, Xu, Y, Zhang, L, Chen, SS, Wang, T & Shen, H 2021, , iScience, vol. 24, no. 11, 103349, pp. 103349. https://doi.org/10.1016/j.isci.2021.103349

The Sympathetic Nervous System Modulates Cancer Vaccine Activity through Monocyte-Derived Cells
Hinkle, L, Liu, Y, Meng, C, Chen, Z, Mai, J, Zhang, L, Xu, Y, Pan, P-Y, Chen, S-H & Shen, H 2021, , Journal of immunology (Baltimore, Md. : 1950). https://doi.org/10.4049/jimmunol.2100719

Combinatorial effect of plk1 inhibition with temozolomide and radiation in glioblastoma
Pandey, A, Tripathi, SC, Mai, J, Hanash, SM, Shen, H, Mitra, S & Rostomily, RC 2021, , Cancers, vol. 13, no. 20, 5114. https://doi.org/10.3390/cancers13205114

Seed-and soil-dependent differences in murine breas tumor microenvironments dictate anti-PD-L1 IgG delivery and therapeutic efficacy
Liu, YT, Goel, S, Kai, M, Guerrero, JAM, Nguyen, T, Mai, J, Shen, H, Ziemys, A & Yokoi, K 2021, , Pharmaceutics, vol. 13, no. 4, 530. https://doi.org/10.3390/pharmaceutics13040530

Synergistic Activation of Antitumor Immunity by a Particulate Therapeutic Vaccine
Mai, J, Li, Z, Xia, X, Zhang, J, Li, J, Liu, H, Shen, J, Ramirez, M, Li, F, Li, Z, Yokoi, K, Liu, X, Mittendorf, EA, Ferrari, M & Shen, H 2021, , Advanced Science, vol. 8, no. 12, 2100166. https://doi.org/10.1002/advs.202100166

Virus-Mimic mRNA Vaccine for Cancer Treatment
Meng, C, Chen, Z, Mai, J, Shi, Q, Tian, S, Hinkle, L, Li, J, Zhang, Z, Ramirez, M, Zhang, L, Xu, Y, Zhang, J, Pan, PY, Chen, SH, Li, H & Shen, H 2021, , advanced therapeutics, vol. 4, no. 11, 2100144. https://doi.org/10.1002/adtp.202100144

Tumor derived UBR5 promotes ovarian cancer growth and metastasis through inducing immunosuppressive macrophages
Song, M, Yeku, OO, Rafiq, S, Purdon, T, Dong, X, Zhu, L, Zhang, T, Wang, H, Yu, Z, Mai, J, Shen, H, Nixon, B, Li, M, Brentjens, RJ & Ma, X 2020, , Nature Communications, vol. 11, no. 1, 6298. https://doi.org/10.1038/s41467-020-20140-0

Reimaging biological barriers affecting distribution and extravasation of PEG/peptide- modified liposomes in xenograft SMMC7721 tumor
Tang, H, Rui, M, Mai, J, Guo, W & Xu, Y 2020, , Acta Pharmaceutica Sinica B, vol. 10, no. 3, pp. 546-556. https://doi.org/10.1016/j.apsb.2019.06.011

Systematic comparison of methods for determining the in vivo biodistribution of porous nanostructured injectable inorganic particles
Nizzero, S, Li, F, Zhang, G, Venuta, A, Borsoi, C, Mai, J, Shen, H, Wolfram, J, Li, Z, Blanco, E & Ferrari, M 2019, , Acta Biomaterialia, vol. 97, pp. 501-512. https://doi.org/10.1016/j.actbio.2019.08.002

Investigation of parameters that determine Nano-DC vaccine transport
Zhang, J, Mai, J, Li, F, Shen, J, Zhang, G, Li, J, Hinkle, LE, Lin, D, Liu, X, Li, Z, Wang, RF, Mittendorf, EA, Ferrari, M & Shen, H 2019, , Biomedical Microdevices, vol. 21, no. 2, 39. https://doi.org/10.1007/s10544-019-0397-6

Tracking biodistribution of myeloid-derived cells in murine models of breast cancer
Li, J, Mai, J, Hinkle, L, Lin, D, Zhang, J, Liu, X, Ramirez, MR, Zu, Y, Lokesh, GL, Volk, DE & Shen, H 2019, , Genes, vol. 10, no. 4, 297. https://doi.org/10.3390/genes10040297

PTGER3 induces ovary tumorigenesis and confers resistance to cisplatin therapy through up-regulation Ras-MAPK/Erk-ETS1-ELK1/CFTR1 axis
Rodriguez-Aguayo, C, Bayraktar, E, Ivan, C, Aslan, B, Mai, J, He, G, Mangala, LS, Jiang, D, Nagaraja, AS, Ozpolat, B, Chavez-Reyes, A, Ferrari, M, Mitra, R, Siddik, ZH, Shen, H, Yang, X, Sood, AK & Lopez-Berestein, G 2019, , EBioMedicine, vol. 40, pp. 290-304. https://doi.org/10.1016/j.ebiom.2018.11.045

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