Jing Yang

Jing Yang, PhD

Associate Professor of Oncology, Academic Institute
Associate Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Yang lab


Publications

Induction of m6A methylation in adipocyte exosomal LncRNAs mediates myeloma drug resistance
Wang, Z, He, J, Bach, DH, Huang, YH, Li, Z, Liu, H, Lin, P & Yang, J 2022, , Journal of Experimental and Clinical Cancer Research, vol. 41, no. 1, 4, pp. 4. https://doi.org/10.1186/s13046-021-02209-w

Promotion of Bone Lesions Through the Myeloma Integrin a6-Mediated Osteolytic Signaling
Liu, H, Wang, Z, He, J, Li, Z, Gao, JY, Liu, R, Lin, P & Yang, J 2021, , Frontiers in Oncology, vol. 11, 692190. https://doi.org/10.3389/fonc.2021.692190

Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma
Li, Z, Liu, H, He, J, Wang, Z, Yin, Z, You, G, Wang, Z, Davis, RE, Lin, P, Bergsagel, PL, Manasanch, EE, Wong, STC, Esnaola, NF, Chang, JC, Orlowski, RZ, Yi, Q & Yang, J 2021, , Cell Metabolism, vol. 33, no. 1, pp. 78-93.e7. https://doi.org/10.1016/j.cmet.2020.12.011

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1: Autophagy
Autophagy Guidelines Group 2021, , Autophagy, vol. 17, no. 1, pp. 1-382. https://doi.org/10.1080/15548627.2020.1797280

Myeloma cells shift osteoblastogenesis to adipogenesis by inhibiting the ubiquitin ligase MURF1 in mesenchymal stem cells
Liu, Z, Liu, H, He, J, Lin, P, Tong, Q & Yang, J 2020, , Science signaling, vol. 13, no. 633, eaay8203. https://doi.org/10.1126/scisignal.aba3176

Reprogrammed marrow adipocytes contribute to myeloma-induced bone disease
Liu, H, He, J, Koh, SP, Zhong, Y, Liu, Z, Wang, Z, Zhang, Y, Li, Z, Tam, BT, Lin, P, Xiao, M, Young, KH, Amini, B, Starbuck, MW, Lee, HC, Navone, NM, Davis, RE, Tong, Q, Bergsagel, PL, Hou, J, Yi, Q, Orlowski, RZ, Gagel, RF & Yang, J 2019, , Science translational medicine, vol. 11, no. 494, eaau9087. https://doi.org/10.1126/scitranslmed.aau9087

The Imipridone ONC201 Induces Apoptosis and Overcomes Chemotherapy Resistance by Up-Regulation of Bim in Multiple Myeloma
Tu, YS, He, J, Liu, H, Lee, HC, Wang, H, Ishizawa, J, Allen, JE, Andreeff, M, Orlowski, RZ, Davis, RE & Yang, J 2017, , Neoplasia (United States), vol. 19, no. 10, pp. 772-780. https://doi.org/10.1016/j.neo.2017.07.009

Resistin induces multidrug resistance in myeloma by inhibiting cell death and upregulating ABC transporter expression
Pang, J, Shi, Q, Liu, Z, He, J, Liu, H, Lin, P, Cui, J & Yang, J 2017, , Haematologica, vol. 102, no. 7, pp. 1273-1280. https://doi.org/10.3324/haematol.2016.154062

RNA Polymerase I Inhibition with CX-5461 as a Novel Therapeutic Strategy to Target MYC in Multiple Myeloma
Lee, HC, Wang, H, Baladandayuthapani, V, Lin, H, He, J, Jones, RJ, Kuiatse, I, Gu, D, Wang, Z, Ma, W, Lim, J, OBrien, S, Keats, J, Yang, J, Davis, RE & Orlowski, RZ 2017, , British Journal of Haematology, vol. 177, no. 1, pp. 80-94. https://doi.org/10.1111/bjh.14525

Role of myeloma-derived MIF in myeloma cell adhesion to bone marrow and chemotherapy response
Yuhuan, Z, Qiang, W, Li, T, Qian, J, Lu, Y, Li, Y, Bi, E, Reu, F, Qin, Y, Drazba, J, Hsi, E, Jing, Y, Cai, Z & Yi, Q 2016, , Journal of the National Cancer Institute, vol. 108, no. 11. https://doi.org/10.1093/jnci/djw131

Thymidine phosphorylase exerts complex effects on bone resorption and formation in myeloma
Liu, H, Liu, Z, Du, J, He, J, Lin, P, Amini, B, Starbuck, MW, Novane, N, Shah, JJ, Davis, RE, Hou, J, Gagel, RF & Yang, J 2016, , Science translational medicine, vol. 8, no. 353, 353ra113. https://doi.org/10.1126/scitranslmed.aad8949

Tight Junction Protein 1 Modulates Proteasome Capacity and Proteasome Inhibitor Sensitivity in Multiple Myeloma via EGFR/JAK1/STAT3 Signaling
Zhang, XD, Baladandayuthapani, V, Lin, H, Mulligan, G, Li, B, Esseltine, DLW, Qi, L, Xu, J, Hunziker, W, Barlogie, B, Usmani, SZ, Zhang, Q, Crowley, J, Hoering, A, Shah, JJ, Weber, DM, Manasanch, EE, Thomas, SK, Li, BZ, Wang, HH, Zhang, J, Kuiatse, I, Tang, JL, Wang, H, He, J, Yang, J, Milan, E, Cenci, S, Ma, WC, Wang, ZQ, Davis, RE, Yang, L & Orlowski, RZ 2016, , Cancer Cell, vol. 29, no. 5, pp. 639-652. https://doi.org/10.1016/j.ccell.2016.03.026

Targeting the Pro-Survival Protein MET with Tivantinib (ARQ 197) Inhibits Growth of Multiple Myeloma Cells
Zaman, S, Shentu, S, Yang, J, He, J, Orlowski, RZ, Stellrecht, CM & Gandhi, V 2015, , Neoplasia (United States), vol. 17, no. 3, pp. 289-300. https://doi.org/10.1016/j.neo.2015.01.006

MicroRNA-451 regulates stemness of side population cells via PI3K/Akt/mTOR signaling pathway in multiple myeloma
Du, J, Liu, S, He, J, Liu, X, Qu, Y, Yan, W, Fan, J, Li, R, Xi, H, Fu, W, Zhang, C, Yang, J & Hou, J 2015, , Oncotarget, vol. 6, no. 17, pp. 14993-15007. https://doi.org/10.18632/oncotarget.3802

Mature adipocytes in bone marrow protect myeloma cells against chemotherapy through autophagy activation
Liu, Z, Xu, J, He, J, Liu, H, Lin, P, Wan, X, Navone, NM, Tong, Q, Kwak, LW, Orlowski, RZ & Yang, J 2015, , Oncotarget, vol. 6, no. 33, pp. 34329-34341. https://doi.org/10.18632/oncotarget.6020

MAPK11 in breast cancer cells enhances osteoclastogenesis and bone resorption
He, Z, He, J, Liu, Z, Xu, J, Yi, SF, Liu, H & Yang, J 2014, , Biochimie, vol. 106, pp. 24-32. https://doi.org/10.1016/j.biochi.2014.07.017

A critical role of autocrine sonic hedgehog signaling in human CD138+myeloma cell survival and drug resistance
Liu, Z, Xu, J, He, J, Zheng, Y, Li, H, Lu, Y, Qian, J, Lin, P, Weber, DM, Yang, J & Yi, Q 2014, , Blood, vol. 124, no. 13, pp. 2061-2071. https://doi.org/10.1182/blood-2014-03-557298

Anti-ß2M monoclonal antibodies kill myeloma cells via cell- and complement-mediated cytotoxicity
Zhang, M, Qian, J, Lan, Y, Lu, Y, Li, H, Hong, B, Zheng, Y, He, J, Yang, J & Yi, Q 2014, , International Journal of Cancer, vol. 135, no. 5, pp. 1132-1141. https://doi.org/10.1002/ijc.28745

Murine Th9 cells promote the survival of myeloid dendritic cells in cancer immunotherapy
Park, J, Li, H, Zhang, M, Lu, Y, Hong, B, Zheng, Y, He, J, Yang, J, Qian, J & Yi, Q 2014, , Cancer Immunology, Immunotherapy, vol. 63, no. 8, pp. 835-845. https://doi.org/10.1007/s00262-014-1557-4

P38 MAPK-inhibited dendritic cells induce superior antitumour immune responses and overcome regulatory T-cell-mediated immunosuppression
Lu, Y, Zhang, M, Wang, S, Hong, B, Wang, Z, Li, H, Zheng, Y, Yang, J, Davis, RE, Qian, J, Hou, J & Yi, Q 2014, , Nature Communications, vol. 5, 4229. https://doi.org/10.1038/ncomms5229