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Susan Xu, PhD

Associate Research Professor of Biostatistics, Institute for Academic Medicine
Associate Research Member, Research Institute
Houston Methodist
Weill Cornell Medical College

After serving as a Research Assistant in the Department of Statistics and Actuarial Science at the University of Waterloo, Dr. Xu received her academic appointment in 2003 as an Assistant Professor in the Center of American Indian Health Research of the College of Public Health at the University of Oklahoma Health Sciences Center in Oklahoma City, Oklahoma. She joined Houston Methodist Research Institute in 2007.

Description of Research

Dr. Xu’s biostatistics work has primarily focused on diabetes, heart disease, and kidney disease in medically underserved populations. She was the biostatistician for the NIH-funded Strong Heart Study, the largest and longest longitudinal study of cardiovascular disease and its risk factors in American Indians.

Dr. Xu’s current biostatistics studies include industry-funded chemotherapy trials for her2neu negative breast cancer patients.

Areas Of Expertise

Diabetes Cardiovascular disease Biostatistics Clinical trial data analysis Survival data analysis Longitudinal data analysis Kidney disease Nutrition
Education & Training

PhD, University of Waterloo, Canada
MS, York University, Toronto, Canada
BSc, Sichuan University

Aptima Human Papillomavirus E6/E7 mRNA Test Results Strongly Associated With Risk for High-Grade Cervical Lesions in Follow-Up Biopsies
Ge, Y, Christensen, P, Luna, E, Armylagos, D, Xu, J, Schwartz, MR & Mody, DR 2018, Journal of Lower Genital Tract Disease. DOI: 10.1097/LGT.0000000000000393

Impact of Cardiovascular Risk on the Relative Benefit and Harm of Intensive Treatment of Hypertension
Phillips, RA, Xu, J, Peterson, LE, Arnold, RM, Diamond, JA & Schussheim, AE 2018, Journal of the American College of Cardiology. DOI: 10.1016/j.jacc.2018.01.074

Estimating Left Ventricular Filling Pressure by Echocardiography
Andersen, OS, Smiseth, OA, Dokainish, H, Abudiab, MM, Schutt, RC, Kumar, A, Sato, K, Harb, S, Gude, E, Remme, EW, Andreassen, AK, Ha, JW, Xu, J, Klein, AL & Nagueh, SF 2017, Journal of the American College of Cardiology, vol 69, no. 15, pp. 1937-1948. DOI: 10.1016/j.jacc.2017.01.058

Shakil, J, Ansari, MZ, Brady, JR, Xu, J & Robbins, RJ 2017, Endocrine Practice, vol 23, no. 2, pp. 163-169. DOI: 10.4158/EP161497.OR

Unrecognized Cognitive Impairment and Its Effect on Heart Failure Readmissions of Elderly Adults
Agarwal, KS, Kazim, R, Xu, J, Borson, S & Taffet, GE 2016, Journal of the American Geriatrics Society, vol 64, no. 11, pp. 2296-2301. DOI: 10.1111/jgs.14471

Clinical performance of the Food and Drug Administration-Approved high-risk HPV test for the detection of high-grade cervicovaginal lesions
Zhou, H, Mody, RR, Luna, E, Armylagos, D, Xu, J, Schwartz, MR, Mody, DR & Ge, Y 2016, Cancer Cytopathology, vol 124, no. 5, pp. 317-323. DOI: 10.1002/cncy.21687

Optimizing evaluation of patients with low-to-intermediate-risk acute chest pain: A randomized study comparing stress myocardial perfusion tomography incorporating stress-only imaging versus cardiac CT
Nabi, F, Kassi, M, Muhyieddeen, K, Chang, SM, Xu, J, Peterson, L, Wray, N, Shirkey, B, Ashton, C & Mahmarian, J 2016, Journal of Nuclear Medicine, vol 57, no. 3, pp. 378-384. DOI: 10.2967/jnumed.115.166595

Multiple Human Papilloma Virus Infections and Their Impact on the Development of High-Risk Cervical Lesions
Salazar, KL, Zhou, HS, Xu, J, Peterson, LE, Schwartz, MR, Mody, DR & Ge, Y 2015, Acta Cytologica, vol 59, no. 5, pp. 391-398. DOI: 10.1159/000442512

Value of CACS compared with ETT and myocardial perfusion imaging for predicting long-term cardiac outcome in asymptomatic and symptomatic patients at low risk for coronary disease: Clinical implications in a multimodality imaging world
Chang, SM, Nabi, F, Xu, J, Pratt, CM, Mahmarian, AC, Frias, ME & Mahmarian, JJ 2015, JACC: Cardiovascular Imaging, vol 8, no. 2, pp. 134-144. DOI: 10.1016/j.jcmg.2014.11.008

Regadenoson provides perfusion results comparable to adenosine in heterogeneous patient populations: A quantitative analysis from the ADVANCE MPI trials
Mahmarian, JJ, Peterson, LE, Xu, J, Cerqueira, MD, Iskandrian, AE, Bateman, TM, Thomas, GS & Nabi, F 2014, Journal of Nuclear Cardiology. DOI: 10.1007/s12350-014-9981-6

Effects of spironolactone treatment in elderly women with heart failure and preserved left ventricular ejection fraction
Kurrelmeyer, KM, Ashton, Y, Xu, JS, Nagueh, SF, Torre-Amione, G & Deswal, A 2014, Journal of Cardiac Failure, vol 20, no. 8, pp. 560-568. DOI: 10.1016/j.cardfail.2014.05.010

Is regadenoson an appropriate stressor for MPI in patients with left bundle branch block or pacemakers?
Thomas, GS, Kinser, CR, Kristy, R, Xu, J & Mahmarian, JJ 2013, Journal of Nuclear Cardiology, vol 20, no. 6, pp. 1076-1085. DOI: 10.1007/s12350-013-9802-3

Dietary patterns and their association with cardiovascular risk factors in a population undergoing lifestyle changes: The Strong Heart Study
Eilat-Adar, S, Mete, M, Fretts, A, Fabsitz, RR, Handeland, V, Lee, ET, Loria, C, Xu, J, Yeh, J & Howard, BV 2013, Nutrition, Metabolism and Cardiovascular Diseases, vol 23, no. 6, pp. 528-535. DOI: 10.1016/j.numecd.2011.12.005

Does quantifying epicardial and intrathoracic fat with noncontrast computed tomography improve risk stratification beyond calcium scoring alone?
Forouzandeh, F, Chang, SM, Muhyieddeen, K, Zaid, RR, Trevino, AR, Xu, J, Nabi, F & Mahmarian, JJ 2013, Circulation: Cardiovascular Imaging, vol 6, no. 1, pp. 58-66. DOI: 10.1161/CIRCIMAGING.112.976316

Differences in risk factors for coronary heart disease among diabetic and nondiabetic individuals from a population with high rates of diabetes: The strong heart study
Xu, J, Lee, ET, Peterson, LE, Devereux, RB, Rhoades, ER, Umans, JG, Best, LG, Howard, WJ, Paranilam, J & Howard, BV 2012, Journal of Clinical Endocrinology and Metabolism, vol 97, no. 10, pp. 3766-3774. DOI: 10.1210/jc.2012-2110

Direct assessment of normal mechanical mitral valve orifice area by real-time 3D echocardiography
Krim, SR, Vivo, RP, Patel, A, Xu, J, Igo, SR, Zoghbi, WA & Little, SH 2012, JACC: Cardiovascular Imaging, vol 5, no. 5, pp. 478-483. DOI: 10.1016/j.jcmg.2011.06.024

Assessing risk in acute chest pain: The value of stress myocardial perfusion imaging in patients admitted through the emergency department
Nabi, F, Chang, SM, Xu, J, Gigliotti, E & Mahmarian, JJ 2012, Journal of Nuclear Cardiology, vol 19, no. 2, pp. 233-243. DOI: 10.1007/s12350-011-9484-7

Initial survival data of kidney transplant patients with pre-transplant monoclonal gammopathy
Soltero, L, Carbajal, H, Xu, J, Mccarthy, J, Suki, WN, Gaber, AO & Adrogué, HE 2012, Clinical Transplantation, vol 26, no. 2, pp. 300-304. DOI: 10.1111/j.1399-0012.2011.01539.x

Flow acceleration time and ratio of acceleration time to ejection time for prosthetic aortic valve function
Ben Zekry, S, Saad, RM, Zkan, M, Al Shahid, MS, Pepi, M, Muratori, M, Xu, J, Little, SH & Zoghbi, WA 2011, JACC: Cardiovascular Imaging, vol 4, no. 11, pp. 1161-1170. DOI: 10.1016/j.jcmg.2011.08.012

Mitral annulus dynamics early after valve repair: Preliminary observations of the effect of resectional versus non-resectional approaches
Ben Zekry, S, Lang, RM, Sugeng, L, McCulloch, ML, Weinert, L, Raman, J, Little, SH, Xu, J, Lawrie, GM & Zoghbi, WA 2011, Journal of the American Society of Echocardiography, vol 24, no. 11, pp. 1233-1242. DOI: 10.1016/j.echo.2011.08.010