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Susan Xu, PhD

Associate Research Professor of Biostatistics, Institute for Academic Medicine
Associate Research Member, Research Institute
Houston Methodist
Weill Cornell Medical College


sxu@houstonmethodist.org
Biography

After serving as a Research Assistant in the Department of Statistics and Actuarial Science at the University of Waterloo, Dr. Xu received her academic appointment in 2003 as an Assistant Professor in the Center of American Indian Health Research of the College of Public Health at the University of Oklahoma Health Sciences Center in Oklahoma City, Oklahoma. She joined Houston Methodist Research Institute in 2007.

Description of Research

Dr. Xu’s biostatistics work has primarily focused on diabetes, heart disease, and kidney disease in medically underserved populations. She was the biostatistician for the NIH-funded Strong Heart Study, the largest and longest longitudinal study of cardiovascular disease and its risk factors in American Indians.

Dr. Xu’s current biostatistics studies include industry-funded chemotherapy trials for her2neu negative breast cancer patients.

Areas Of Expertise

Diabetes Cardiovascular disease Biostatistics Clinical trial data analysis Survival data analysis Longitudinal data analysis Kidney disease Nutrition
Education & Training

PhD, University of Waterloo, Canada
MS, York University, Toronto, Canada
BSc, Sichuan University
Publications

Interobserver Variability in Applying American Society of Echocardiography/European Association of Cardiovascular Imaging 2016 Guidelines for Estimation of Left Ventricular Filling Pressure
for Diastolic Function Assessment Collaborators 2019, Circulation. Cardiovascular imaging, vol. 12, no. 1, pp. e008122. https://doi.org/10.1161/CIRCIMAGING.118.008122

Overactive Bladder Symptoms After Pelvic Organ Prolapse Repair
Johnson, JR, High, RA, Dziadek, O, Ocon, A, Muir, TW, Xu, J & Antosh, DD 2019, Female Pelvic Medicine and Reconstructive Surgery. https://doi.org/10.1097/SPV.0000000000000700

Role of HPV genotyping in risk assessment among cytology diagnosis categories: Analysis of 4562 cases with cytology-HPV cotesting and follow-up biopsies
Ge, Y, Christensen, P, Luna, E, Armylagos, D, Xu, J, Schwartz, MR & Mody, DR 2019, International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, vol. 29, no. 2, pp. 234-241. https://doi.org/10.1136/ijgc-2018-000024

Age-specific 3-year cumulative risk of cervical cancer and high-grade dysplasia on biopsy in 9434 women who underwent HPV cytology cotesting
Ge, Y, Christensen, PA, Luna, E, Armylagos, D, Xu, S, Hsu, JW, Zhou, H, Schwartz, MR & Mody, DR 2019, Cancer cytopathology. https://doi.org/10.1002/cncy.22192

Myocardial Fibrosis in Patients With Primary Mitral Regurgitation With and Without Prolapse
Kitkungvan, D, Nabi, F, Kim, RJ, Bonow, RO, Khan, MA, Xu, J, Little, SH, Quinones, MA, Lawrie, GM, Zoghbi, WA & Shah, DJ 2018, Journal of the American College of Cardiology, vol. 72, no. 8, pp. 823-834. https://doi.org/10.1016/j.jacc.2018.06.048

Reply: Validation of Predicted Cardiovascular Disease Risk to Guide Intensity of Blood Pressure Treatment
Phillips, RA, Arnold, RM, Xu, J, Diamond, JA & Peterson, LE 2018, Journal of the American College of Cardiology, vol. 72, no. 7, pp. 820-821. https://doi.org/10.1016/j.jacc.2018.06.012

Aptima Human Papillomavirus E6/E7 mRNA Test Results Strongly Associated with Risk for High-Grade Cervical Lesions in Follow-Up Biopsies
Ge, Y, Christensen, P, Luna, E, Armylagos, D, Xu, J, Schwartz, MR & Mody, DR 2018, Journal of Lower Genital Tract Disease, vol. 22, no. 3, pp. 195-200. https://doi.org/10.1097/LGT.0000000000000393

Optimal positioning of self-expanding valves before deployment decreases paravalvular regurgitation following transcatheter aortic valve replacement
Dadu, RT, Xu, J, Rehman, H, von Ballmoos, MW, Barker, CM, Reyes, M, Ramchandani, M, Reul, RM, Reardon, MJ & Kleiman, NS 2018, Catheterization and Cardiovascular Interventions. https://doi.org/10.1002/ccd.27829

Impact of Cardiovascular Risk on the Relative Benefit and Harm of Intensive Treatment of Hypertension
Phillips, RA, Xu, J, Peterson, LE, Arnold, RM, Diamond, JA & Schussheim, AE 2018, Journal of the American College of Cardiology, vol. 71, no. 15, pp. 1601-1610. https://doi.org/10.1016/j.jacc.2018.01.074

Estimating Left Ventricular Filling Pressure by Echocardiography
Andersen, OS, Smiseth, OA, Dokainish, H, Abudiab, MM, Schutt, RC, Kumar, A, Sato, K, Harb, S, Gude, E, Remme, EW, Andreassen, AK, Ha, JW, Xu, J, Klein, AL & Nagueh, SF 2017, Journal of the American College of Cardiology, vol. 69, no. 15, pp. 1937-1948. https://doi.org/10.1016/j.jacc.2017.01.058

LOWER RATES OF RESIDUAL/RECURRENT DISEASE IN PATIENTS WITH INCIDENTALLY DISCOVERED THYROID CARCINOMA
Shakil, J, Ansari, MZ, Brady, JR, Xu, J & Robbins, RJ 2017, Endocrine Practice, vol. 23, no. 2, pp. 163-169. https://doi.org/10.4158/EP161497.OR

Unrecognized Cognitive Impairment and Its Effect on Heart Failure Readmissions of Elderly Adults
Agarwal, KS, Kazim, R, Xu, S, Borson, S & Taffet, G 2016, Journal of the American Geriatrics Society, vol. 64, no. 11, pp. 2296-2301. https://doi.org/10.1111/jgs.14471

Clinical performance of the Food and Drug Administration-Approved high-risk HPV test for the detection of high-grade cervicovaginal lesions
Zhou, H, Mody, RR, Luna, E, Armylagos, D, Xu, S, Schwartz, MR, Mody, DR & Ge, Y 2016, Cancer Cytopathology, vol. 124, no. 5, pp. 317-323. https://doi.org/10.1002/cncy.21687

Optimizing evaluation of patients with low-to-intermediate-risk acute chest pain: A randomized study comparing stress myocardial perfusion tomography incorporating stress-only imaging versus cardiac CT
Nabi, F, Kassi, M, Muhyieddeen, K, Chang, SM, Xu, J, Peterson, L, Wray, N, Shirkey, B, Ashton, C & Mahmarian, J 2016, Journal of Nuclear Medicine, vol. 57, no. 3, pp. 378-384. https://doi.org/10.2967/jnumed.115.166595

Multiple Human Papilloma Virus Infections and Their Impact on the Development of High-Risk Cervical Lesions
Salazar, KL, Zhou, HS, Xu, S, Peterson, LE, Schwartz, MR, Mody, DR & Ge, Y 2015, Acta cytologica, vol. 59, no. 5, pp. 391-398. https://doi.org/10.1159/000442512

Value of CACS compared with ETT and myocardial perfusion imaging for predicting long-term cardiac outcome in asymptomatic and symptomatic patients at low risk for coronary disease: Clinical implications in a multimodality imaging world
Chang, S-M, Nabi, F, Xu, S, Pratt, C, Mahmarian, AC, Frias, ME & Mahmarian, JJ 2015, JACC: Cardiovascular Imaging, vol. 8, no. 2, pp. 134-144. https://doi.org/10.1016/j.jcmg.2014.11.008

Regadenoson provides perfusion results comparable to adenosine in heterogeneous patient populations: A quantitative analysis from the ADVANCE MPI trials
Mahmarian, JJ, Peterson, LE, Xu, J, Cerqueira, MD, Iskandrian, AE, Bateman, TM, Thomas, GS & Nabi, F 2014, Journal of Nuclear Cardiology. https://doi.org/10.1007/s12350-014-9981-6

Effects of spironolactone treatment in elderly women with heart failure and preserved left ventricular ejection fraction
Kurrelmeyer, KM, Ashton, Y, Xu, JS, Nagueh, SF, Torre-Amione, G & Deswal, A 2014, Journal of Cardiac Failure, vol. 20, no. 8, pp. 560-568. https://doi.org/10.1016/j.cardfail.2014.05.010

Is regadenoson an appropriate stressor for MPI in patients with left bundle branch block or pacemakers?
Thomas, GS, Kinser, CR, Kristy, R, Xu, S & Mahmarian, JJ 2013, Journal of Nuclear Cardiology, vol. 20, no. 6, pp. 1076-1085. https://doi.org/10.1007/s12350-013-9802-3

Dietary patterns and their association with cardiovascular risk factors in a population undergoing lifestyle changes: The Strong Heart Study
Eilat-Adar, S, Mete, M, Fretts, A, Fabsitz, RR, Handeland, V, Lee, ET, Loria, C, Xu, J, Yeh, J & Howard, BV 2013, Nutrition, Metabolism and Cardiovascular Diseases, vol. 23, no. 6, pp. 528-535. https://doi.org/10.1016/j.numecd.2011.12.005

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