Jian Chen

Jian Chen, BM, PhD

Associate Professor of Clinical Pathology and Genomic Medicine, Academic Institute
Associate Clinical Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Interpreting coagulation mixing study results in the era of direct oral anticoagulants
Kim, MJ, Salazar, E, Philips, B, Rice, L, Castillo, B, Leveque, C & Chen, J 2024, , Blood Coagulation and Fibrinolysis, vol. 35, no. 1, pp. 23-26. https://doi.org/10.1097/MBC.0000000000001267

Recurrent Gastrointestinal Bleeding in a Middle-Aged Man
Gowani, F, Phillips, B, Leveque, C, Castillo, B, Chen, J, Chandler, W, Rice, L & Salazar, E 2022, , Lab Medicine, vol. 53, no. 4, pp. E91-E94. https://doi.org/10.1093/labmed/lmab104

Aptamer–Gemcitabine Conjugates with Enzymatically Cleavable Linker for Targeted Delivery and Intracellular Drug Release in Cancer Cells
Qi, J, Zeng, Z, Chen, Z, Nipper, C, Liu, X, Wan, Q, Chen, J, Tung, CH & Zu, Y 2022, , Pharmaceuticals, vol. 15, no. 5, 558. https://doi.org/10.3390/ph15050558

Impact of mobilization regimen on multiday collection of peripheral blood CD34+ cells by large volume leukapheresis
Siddiqui, I, Shmookler, A, Biller, E, Hardy, T, Hartage, R, Losos, M & Chen, J 2022, , Transfusion, vol. 62, no. 4, pp. 857-862. https://doi.org/10.1111/trf.16842

Getting blood out of a stone: Identification and management of patients with poor hematopoietic cell mobilization
Chen, J, Lazarus, HM, Dahi, PB, Avecilla, S & Giralt, SA 2021, , Blood Reviews, vol. 47, 100771. https://doi.org/10.1016/j.blre.2020.100771

Ultrasound-based criteria for adequate peripheral venous access in therapeutic apheresis procedures
Salazar, E, Gowani, F, Segura, F, Passe, H, Seamster, L, Chapman, B, Joubert, F, Hopson, S, Easley, T, Garcia, S, Miguel, R, Medina, C, Musharbash, A, Castillo, B, Chen, J, Ipe, T & Leveque, C 2021, , Journal of Clinical Apheresis, vol. 36, no. 6, pp. 797-801. https://doi.org/10.1002/jca.21930

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1: Autophagy
Autophagy Guidelines Group 2021, , Autophagy, vol. 17, no. 1, pp. 1-382. https://doi.org/10.1080/15548627.2020.1797280

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1: Autophagy
Autophagy Guidelines Group 2021, , Autophagy, vol. 17, no. 1, pp. 1-382. https://doi.org/10.1080/15548627.2020.1797280

Significantly Decreased Mortality in a Large Cohort of Coronavirus Disease 2019 (COVID-19) Patients Transfused Early with Convalescent Plasma Containing High-Titer Anti–Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Protein IgG
Salazar, E, Christensen, PA, Graviss, EA, Nguyen, DT, Castillo, B, Chen, J, Lopez, BV, Eagar, TN, Yi, X, Zhao, P, Rogers, J, Shehabeldin, A, Joseph, D, Masud, F, Leveque, C, Olsen, RJ, Bernard, DW, Gollihar, J & Musser, JM 2021, , American Journal of Pathology, vol. 191, no. 1, pp. 90-107. https://doi.org/10.1016/j.ajpath.2020.10.008, https://doi.org/10.1016/j.ajpath.2020.10.008

Convalescent plasma anti-SARS-CoV-2 spike protein ectodomain and receptor binding domain IgG correlate with virus neutralization
Salazar, E, Kuchipudi, SV, Christensen, PA, Eagar, T, Yi, X, Zhao, P, Jin, Z, Long, SW, Olsen, RJ, Chen, J, Castillo, B, Leveque, C, Towers, D, Lavinder, JJ, Gollihar, J, Cardona, JA, Ippolito, GC, Nissly, RH, Bird, I, Greenawalt, D, Rossi, RM, Gontu, A, Srinivasan, S, Poojary, I, Cattadori, IM, Hudson, P, Josleyn, NM, Prugar, L, Huie, KE, Herbert, AS, Bernard, DW, Dye, JM, Kapur, V & Musser, JM 2020, , The Journal of clinical investigation, vol. 130, no. 12, pp. 6728-6738. https://doi.org/10.1172/JCI141206

Evaluation of peripheral blood mononuclear cell collection by leukapheresis
Chen, J, Goss, C, Avecilla, ST, Hong, H, Walsh, E, Wuest, D, Maslak, P & Pessin, MS 2019, , Transfusion, vol. 59, no. 5, pp. 1765-1772. https://doi.org/10.1111/trf.15186

Irradiation and prolonged storage of red cells are associated with increased adverse events
Chen, J, Biller, E, Losos, M, Li, J, Hamad, D, Blower, L, Grevenow, M & Oakley, J 2018, , Vox Sanguinis, vol. 113, no. 5, pp. 468-475. https://doi.org/10.1111/vox.12660

Prolonged platelet storage associated with increased frequency of transfusion-related adverse events
Losos, M, Biller, E, Li, J, Blower, L, Hamad, D, Patel, G, Scrape, S, Cataland, S & Chen, J 2018, , Vox Sanguinis, vol. 113, no. 2, pp. 170-176. https://doi.org/10.1111/vox.12622

The tipping point: The critical role of therapeutic apheresis in a case of refractory acquired hemophilia
Losos, M, Scrape, S, Joshi, S, Shmookler, A & Chen, J 2017, , Journal of Clinical Apheresis, vol. 32, no. 6, pp. 564-566. https://doi.org/10.1002/jca.21509

Increased complement activation during platelet storage
Chen, J, Losos, M, Yang, S, Li, J, Wu, H & Cataland, S 2017, , Transfusion, vol. 57, no. 9, pp. 2182-2188. https://doi.org/10.1111/trf.14215

Acute hemolytic transfusion reaction caused by a red cell antibody that was missed by pretransfusion testing using tube method
Shmookler, A, Hamad, D, Scrape, S & Chen, J 2017, , Lab Medicine, vol. 48, no. 3, pp. 258-261. https://doi.org/10.1093/labmed/lmx037

Warm Autoimmune Hemolytic Anemia and Direct Antiglobulin Testing with a False-Negative Result in a 53-Year-Old Man: The DAT Will Set You Free
Losos, M, Hamad, D, Joshi, S, Scrape, S & Chen, J 2016, , Laboratory Medicine, vol. 47, no. 3, pp. 227-232. https://doi.org/10.1093/labmed/lmw018

Evaluation of prothrombin time and activated partial thromboplastin time mixing studies using an estimated factor correction method
Chen, J, Phillips, B & Chandler, WL 2016, , Blood Coagulation and Fibrinolysis, vol. 27, no. 1, pp. 90-96. https://doi.org/10.1097/MBC.0000000000000375