Jian Chen, MD, PhD

Associate Professor of Clinical Pathology and Genomic Medicine, Academic Institute
Associate Clinical Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Significantly Decreased Mortality in a Large Cohort of Coronavirus Disease 2019 (COVID-19) Patients Transfused Early with Convalescent Plasma Containing High-Titer Anti–Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Protein IgG
Salazar, E, Christensen, PA, Graviss, EA, Nguyen, DT, Castillo, B, Chen, J, Lopez, BV, Eagar, TN, Yi, X, Zhao, P, Rogers, J, Shehabeldin, A, Joseph, D, Masud, F, Leveque, C, Olsen, RJ, Bernard, DW, Gollihar, J & Musser, JM 2021, , American Journal of Pathology, vol. 191, no. 1, pp. 90-107. https://doi.org/10.1016/j.ajpath.2020.10.008, https://doi.org/10.1016/j.ajpath.2020.10.008

Convalescent plasma anti-SARS-CoV-2 spike protein ectodomain and receptor binding domain IgG correlate with virus neutralization
Salazar, E, Kuchipudi, SV, Christensen, PA, Eagar, T, Yi, X, Zhao, P, Jin, Z, Long, SW, Olsen, RJ, Chen, J, Castillo, B, Leveque, C, Towers, D, Lavinder, JJ, Gollihar, J, Cardona, JA, Ippolito, GC, Nissly, RH, Bird, I, Greenawalt, D, Rossi, RM, Gontu, A, Srinivasan, S, Poojary, I, Cattadori, IM, Hudson, P, Josleyn, NM, Prugar, L, Huie, KE, Herbert, AS, Bernard, DW, Dye, JM, Kapur, V & Musser, JM 2020, , The Journal of clinical investigation, vol. 130, no. 12, pp. 6728-6738. https://doi.org/10.1172/JCI141206

Prolonged platelet storage associated with increased frequency of transfusion-related adverse events
Losos, M, Biller, E, Li, J, Blower, L, Hamad, D, Patel, G, Scrape, S, Cataland, S & Chen, J 2018, , Vox Sanguinis, vol. 113, no. 2, pp. 170-176. https://doi.org/10.1111/vox.12622

The tipping point: The critical role of therapeutic apheresis in a case of refractory acquired hemophilia
Losos, M, Scrape, S, Joshi, S, Shmookler, A & Chen, J 2017, , Journal of Clinical Apheresis, vol. 32, no. 6, pp. 564-566. https://doi.org/10.1002/jca.21509

Increased complement activation during platelet storage
Chen, J, Losos, M, Yang, S, Li, J, Wu, H & Cataland, S 2017, , Transfusion, vol. 57, no. 9, pp. 2182-2188. https://doi.org/10.1111/trf.14215

Acute hemolytic transfusion reaction caused by a red cell antibody that was missed by pretransfusion testing using tube method
Shmookler, A, Hamad, D, Scrape, S & Chen, J 2017, , Lab Medicine, vol. 48, no. 3, pp. 258-261. https://doi.org/10.1093/labmed/lmx037

Warm Autoimmune Hemolytic Anemia and Direct Antiglobulin Testing with a False-Negative Result in a 53-Year-Old Man: The DAT Will Set You Free
Losos, M, Hamad, D, Joshi, S, Scrape, S & Chen, J 2016, , Laboratory Medicine, vol. 47, no. 3, pp. 227-232. https://doi.org/10.1093/labmed/lmw018

Evaluation of prothrombin time and activated partial thromboplastin time mixing studies using an estimated factor correction method
Chen, J, Phillips, B & Chandler, WL 2016, , Blood Coagulation and Fibrinolysis, vol. 27, no. 1, pp. 90-96. https://doi.org/10.1097/MBC.0000000000000375