Jesus M. Eraso

Jesus M. Eraso, PhD

Assistant Research Professor of Pathology & Genomic Medicine, Academic Institute
Assistant Research Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Publications

Genome-Wide Transposon Mutagenesis Screens Identify Group A Streptococcus Genes Affecting Susceptibility to ß-Lactam Antibiotics
Zhu, L, Eraso, JM, Mangham, RE, Saavedra, MO, Olsen, RJ, Beres, SB & Musser, JM 2022, , Journal of bacteriology, vol. 204, no. 12. https://doi.org/10.1128/jb.00287-22

Genome-wide transposon mutagenesis screens identify group A streptococcus genes affecting susceptibility to beta-lactam antibiotics
Zhu, L, Eraso, JM, Mangham, R, Ojeda Saavedra, M, Olsen, RJ, Beres, SB & Musser, JM 2022, , Journal of bacteriology.

Polymorphisms in RocA Contribute to the Molecular Pathogenesis of Serotype M28 Group A Streptococcus
Bernard, PE, Kachroo, P, Eraso, JM, Zhu, L, Madry, JE, Linson, SE, Saavedra, MO, Cantu, CC, Musser, JM & Olsen, RJ 2020, , FASEB Journal, vol. 34 (S1), no. 1-1. https://doi.org/10.1096/fasebj.2020.34.s1.03097

New pathogenesis mechanisms and translational leads identified by multidimensional analysis of necrotizing myositis in primates
Kachroo, P, Eraso, JM, Olsen, RJ, Zhu, L, Kubiak, SL, Pruitt, L, Yerramilli, P, Cantu, CC, Saavedra, MO, Pensar, J, Corander, J, Jenkins, L, Kao, L, Granillo, A, Porter, AR, Deleo, FR & Musser, JM 2020, , mBio, vol. 11, no. 1, e03363-19. https://doi.org/10.1128/mBio.03363-19

Genetic heterogeneity of the Spy1336/R28—Spy1337 virulence axis in Streptococcus pyogenes and effect on gene transcript levels and pathogenesis
Eraso, JM, Kachroo, P, Olsen, RJ, Beres, SB, Zhu, L, Badu, T, Shannon, S, Cantu, CC, Saavedra, MO, Kubiak, SL, Porter, AR, DeLeo, FR & Musser, JM 2020, , PLoS ONE, vol. 15, no. 3, e0229064. https://doi.org/10.1371/journal.pone.0229064

Polymorphisms in Regulator of Cov Contribute to the Molecular Pathogenesis of Serotype M28 Group A Streptococcus
Bernard, PE, Kachroo, P, Eraso, JM, Zhu, L, Madry, JE, Linson, SE, Ojeda Saavedra, M, Cantu, C, Musser, JM & Olsen, RJ 2019, , American Journal of Pathology, vol. 189, no. 10, pp. 2002-2018. https://doi.org/10.1016/j.ajpath.2019.06.009

Integrated analysis of population genomics, transcriptomics and virulence provides novel insights into Streptococcus pyogenes pathogenesis
Kachroo, P, Eraso, JM, Beres, SB, Olsen, RJ, Zhu, L, Nasser, W, Bernard, PE, Cantu, CC, Saavedra, MO, Arredondo, MJ, Strope, B, Do, H, Kumaraswami, M, Vuopio, J, Gröndahl-Yli-Hannuksela, K, Kristinsson, KG, Gottfredsson, M, Pesonen, M, Pensar, J, Davenport, ER, Clark, AG, Corander, J, Caugant, DA, Gaini, S, Magnussen, MD, Kubiak, SL, Nguyen, HAT, Long, SW, Porter, AR, DeLeo, FR & Musser, JM 2019, , Nature Genetics, vol. 51, no. 3, pp. 548-559. https://doi.org/10.1038/s41588-018-0343-1

Gene fitness landscape of group A streptococcus during necrotizing myositis
Zhu, L, Olsen, RJ, Beres, SB, Eraso, JM, Saavedra, MO, Kubiak, SL, Cantu, CC, Jenkins, L, Charbonneau, ARL, Waller, AS & Musser, JM 2019, , The Journal of clinical investigation, vol. 129, no. 2, pp. 887-901. https://doi.org/10.1172/JCI124994

RocA has serotype-specific gene regulatory and pathogenesis activities in serotype M28 Group A streptococcus
Bernard, PE, Kachroo, P, Zhu, L, Beres, SB, Eraso, JM, Kajani, Z, Long, SW, Musser, JM & Olsen, RJ 2018, , Infection and Immunity, vol. 86, no. 11, e00467-18. https://doi.org/10.1128/IAI.00467-18

Genomic Landscape of Intrahost Variation in Group A Streptococcus: Repeated and Abundant Mutational Inactivation of the fabT Gene Encoding a Regulator of Fatty Acid Synthesis
Eraso, JM, Olsen, RJ, Beres, SB, Kachroo, P, Porter, AR, Nasser, W, Bernard, PE, DeLeo, FR & Musser, JM 2016, , Infection and Immunity, vol. 84, no. 12, pp. 3268-3281. https://doi.org/10.1128/IAI.00608-16

The highly conserved MraZ protein is a transcriptional regulator in Escherichia coli
Eraso, JM, Markillie, LM, Mitchell, HD, Taylor, RC, Orr, G & Margolin, W 2014, , Journal of bacteriology, vol. 196, no. 11, pp. 2053-2066. https://doi.org/10.1128/JB.01370-13

Transcriptome response to nitrosative stress in Rhodobacter sphaeroides 2.4.1
Arai, H, Hyeob Roh, J, Eraso, JM & Kaplan, S 2013, , Bioscience, Biotechnology and Biochemistry, vol. 77, no. 1, pp. 111-118. https://doi.org/10.1271/bbb.120601

The Early Divisome Protein FtsA Interacts Directly through Its 1c: Subdomain with the Cytoplasmic Domain of the Late Divisome: Protein FtsN
Busiek, KK, Eraso, JM, Wang, Y & Margolin, W 2012, , Journal of bacteriology, vol. 194, no. 8, pp. 1989-2000. https://doi.org/10.1128/JB.06683-11

Bacterial cell wall: Thinking globally, actin locally
Eraso, JM & Margolin, W 2011, , Current Biology, vol. 21, no. 16, pp. R628-R630. https://doi.org/10.1016/j.cub.2011.06.056

Regulation of gene expression by PrrA in Rhodobacter sphaeroides 2.4.1: Role of polyamines and DNA topology
Eraso, JM & Kaplan, S 2009, , Journal of bacteriology, vol. 191, no. 13, pp. 4341-4352. https://doi.org/10.1128/JB.00243-09

Half-site DNA sequence and spacing length contributions to PrrA binding to PrrA site 2 of RSP3361 in Rhodobacter sphaeroides 2.4.1
Eraso, JM & Kaplan, S 2009, , Journal of bacteriology, vol. 191, no. 13, pp. 4353-4364. https://doi.org/10.1128/JB.00244-09

The use of chromatin immunoprecipitation to define PpsR binding activity in rhodobacter sphaeroides 2.4.1
Bruscella, P, Eraso, JM, Jung, HR & Kaplan, S 2008, , Journal of bacteriology, vol. 190, no. 20, pp. 6817-6828. https://doi.org/10.1128/JB.00719-08

Role of the global transcriptional regulator PrrA in Rhodobacter sphaeroides 2.4.1: Combined transcriptome and proteome analysis
Eraso, JM, Jung, HR, Zeng, X, Callister, SJ, Lipton, MS & Kaplan, S 2008, , Journal of bacteriology, vol. 190, no. 14, pp. 4831-4848. https://doi.org/10.1128/JB.00301-08

Postgenomic adventures with Rhodobacter sphaeroides
Mackenzie, C, Eraso, JM, Choudhary, M, Jung, HR, Zeng, X, Bruscella, P, Puskás, Á & Kaplan, S 2007, , Annual Review of Microbiology, vol. 61, pp. 283-307. https://doi.org/10.1146/annurev.micro.61.080706.093402

Combining microarray and genomic data to predict DNA binding motifs
Mao, L, Mackenzie, C, Roh, JH, Eraso, JM, Kaplan, S & Resat, H 2005, , Microbiology, vol. 151, no. 10, pp. 3197-3213. https://doi.org/10.1099/mic.0.28167-0

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