James C. Major, MD, PhD

Assistant Professor of Clinical Ophthalmology, Academic Institute
Houston Methodist
Weill Cornell Medical College


Education & Training

MD, Baylor College of Medicine
Clinical Fellowship, Bascom Palmer Eye Inst & Hosp
Residency, Bascom Palmer Eye Inst & Hosp
Internship, Carilion Roanoke Memorial Hospital
Publications

THE TEXAS TACO TECHNIQUE FOR INTERNAL LIMITING MEMBRANE FLAP IN LARGE FULL-THICKNESS MACULAR HOLES: A Short-Term Pilot Study
Major, JC, Lampen, SIR, Wykoff, CC, Ou, WC, Brown, DM, Wong, TP & Shah, AR 2020, , Retina (Philadelphia, Pa.), vol. 40, no. 3, pp. 552-556. https://doi.org/10.1097/IAE.0000000000002431

Intravitreal Aflibercept for Retinal Nonperfusion in Proliferative Diabetic Retinopathy: Outcomes from the Randomized RECOVERY Trial
Intravitreal Aflibercept for Retinal Nonperfusion in Proliferative Diabetic Retinopathy Study Group 2019, , Ophthalmology Retina, vol. 3, no. 12, pp. 1076-1086. https://doi.org/10.1016/j.oret.2019.07.011

Randomized Trial of Treat and Extend Ranibizumab With and Without Navigated Laser Versus Monthly Dosing for Diabetic Macular Edema: TREX-DME 2-Year Outcomes
TREX-DME Study Group 2019, , American Journal of Ophthalmology, vol. 202, pp. 91-99. https://doi.org/10.1016/j.ajo.2019.02.005

Fovea-sparing rhegmatogenous retinal detachments: impact of clinical factors including time to surgery on visual and anatomic outcomes
Lee, IT, Lampen, SIR, Wong, TP, Major, JC & Wykoff, CC 2019, , Graefes Archive for Clinical and Experimental Ophthalmology, vol. 257, no. 5, pp. 883-889. https://doi.org/10.1007/s00417-018-04236-4

Developments in fovea-sparing RRD repair: Reconsidering the timing of surgery
Major, JC, Hariprasad, SM & Rusakevich, AM 2019, , Ophthalmic Surgery Lasers and Imaging Retina, vol. 50, no. 7, pp. 408-410. https://doi.org/10.3928/23258160-20190703-01

Progression of Geographic Atrophy in Age-related Macular Degeneration: AREDS2 Report Number 16
AREDS2 Research Group 2018, , Ophthalmology, vol. 125, no. 12, pp. 1913-1928. https://doi.org/10.1016/j.ophtha.2018.05.028

Topographic Correspondence of Macular Atrophy With Choroidal Neovascularization in Ranibizumab-treated Eyes of the TREX-AMD Trial
TREX-AMD Study Group 2018, , American Journal of Ophthalmology, vol. 192, pp. 84-90. https://doi.org/10.1016/j.ajo.2018.05.008

Topographic Correspondence of Macular Atrophy With Choroidal Neovascularization in Ranibizumab-treated Eyes of the TREX-AMD Trial
TREX-AMD Study Group 2018, , American Journal of Ophthalmology, vol. 192, pp. 84-90. https://doi.org/10.1016/j.ajo.2018.05.008

Comparison of monthly vs treat-and-extend regimens for individuals with macular edema who respond well to anti-vascular endothelial growth factor medications: Secondary outcomes from the SCORE2 randomized clinical trial
SCORE2 Investigator Group 2018, , JAMA Ophthalmology, vol. 136, no. 4, pp. 337-345. https://doi.org/10.1001/jamaophthalmol.2017.6843

Natural History of Drusenoid Pigment Epithelial Detachment Associated with Age-Related Macular Degeneration: Age-Related Eye Disease Study 2 Report No. 17
Age-Related Eye Disease Study 2 Research Group 2019, , Ophthalmology, vol. 126, no. 2, pp. 261-273. https://doi.org/10.1016/j.ophtha.2018.08.017

Effect of adding dexamethasone to continued ranibizumab treatment in patients with persistent diabetic macular edema: A DRCR network phase 2 randomized clinical trial
Diabetic Retinopathy Clinical Research Network 2018, , JAMA Ophthalmology, vol. 136, no. 1, pp. 29-38. https://doi.org/10.1001/jamaophthalmol.2017.4914

Plasma Vascular Endothelial Growth Factor Concentrations after Intravitreous Anti–Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema
Diabetic Retinopathy Clinical Research Network 2018, , Ophthalmology, vol. 125, no. 7, pp. 1054-1063. https://doi.org/10.1016/j.ophtha.2018.01.019

Macular Atrophy in Neovascular Age-Related Macular Degeneration with Monthly versus Treat-and-Extend Ranibizumab: Findings from the TREX-AMD Trial
Abdelfattah, NS, Al-Sheikh, M, Pitetta, S, Mousa, A, Sadda, SVR, Wykoff, CC, Wykoff, CC, Croft, DE, Brown, DM, Wang, R, Payne, JF, Clark, L, Sadda, SVR, Benz, MS, Chen, E, Fish, RH, Johnson, DL, Kim, RY, Major, JC, OMalley, RE, Schefler, AC, Shah, AR, Vance, SK, Wells, JA & Wong, TP 2017, , Ophthalmology, vol. 124, no. 2, pp. 215-223. https://doi.org/10.1016/j.ophtha.2016.10.002

THE ASSOCIATION OF EPIRETINAL MEMBRANE WITH MACULAR HOLE FORMATION AFTER RHEGMATOGENOUS RETINAL DETACHMENT REPAIR
Khurana, RN, Wykoff, CC, Bansal, AS, Akiyama, K, Palmer, JD, Chen, E, Chang, LK, Major, JC, Wu, C, Wang, R, Croft, DE & Wong, TP 2016, , Retina. https://doi.org/10.1097/IAE.0000000000001307

Diagnostic and therapeutic challenges
Phillis, CA, Bourke, RD & Major, JC 2016, Retina, vol. 36, no. 6, pp. 1234-1236. https://doi.org/10.1097/IAE.0000000000000880

Choroidal Neovascularization Secondary to Alexandrite Laser Exposure
Wang, R, Wykoff, CC, Christie, L, Croft, DE, Major, JC, Fish, RH & Brown, DM 2016, , Retinal Cases and Brief Reports, vol. 10, no. 3, pp. 244-248. https://doi.org/10.1097/ICB.0000000000000241

Endophthalmitis after intravitreal injection: Role of prophylactic topical ophthalmic antibiotics
Li, AL, Wykoff, CC, Wang, R, Chen, E, Benz, MS, Fish, RH, Wong, TP, Major, JC, Brown, DM, Schefler, AC, Kim, RY & Omalley, RE 2016, , Retina, vol. 36, no. 7, pp. 1349-1356. https://doi.org/10.1097/IAE.0000000000000901

Aflibercept for pigment epithelial detachment for previously treated neovascular age-related macular degeneration
Major, JC, Wykoff, CC, Croft, DE, Wang, R, Mariani, AF, Lehmann, AE & Brown, DM 2015, , Canadian Journal of Ophthalmology, vol. 50, no. 5, 715, pp. 373-377. https://doi.org/10.1016/j.jcjo.2014.12.012

5Q with James C. Major Jr, MD, PHD
Major, JC 2015, , Retina Today, vol. 2015, no. September2015, pp. 81-82.

Progressive retinal nonperfusion in ischemic central retinal vein occlusion
Wykoff, CC, Brown, DM, Croft, DE, Major, JC & Wong, TP 2015, , Retina, vol. 35, no. 1, pp. 43-47. https://doi.org/10.1097/IAE.0000000000000277