Gobardhan Das, PhD

Adjunct Professor of Pathology and Genomic Medicine, Academic Institute
Full Affiliate Member, Research Institute
Houston Methodist


The 1, 2-ethylenediamine SQ109 protects against tuberculosis by promoting M1 macrophage polarization through the p38 MAPK pathway
Singh, M, Kumar, S, Singh, B, Jain, P, Kumari, A, Pahuja, I, Chaturvedi, S, Prasad, DVR, Dwivedi, VP & Das, G 2022, , Communications Biology, vol. 5, no. 1, 759. https://doi.org/10.1038/s42003-022-03693-2

Erratum: Luteolin-mediated Kv1.3 K+channel inhibition augments BCG vaccine efficacy against tuberculosis by promoting central memory T cell responses in mice (PLoS Pathogens (2020) 16:9 (e1008887) DOI: 10.1371/journal.ppat.1008887)
Singh, DK, Dwivedi, VP, Singh, SP, Kumari, A, Sharma, SK, Ranganathan, A, Van Kaer, L & Das, G 2021, , PLoS pathogens, vol. 17, no. 8 August, e1009896. https://doi.org/10.1371/journal.ppat.1009896

Luteolin as a potential host-directed immunotherapy adjunct to isoniazid treatment of tuberculosis
Singh, DK, Tousif, S, Bhaskar, A, Devi, A, Negi, K, Moitra, B, Ranganathan, A, Dwivedi, VP & Das, G 2021, , PLoS pathogens, vol. 17, no. 8, e1009805. https://doi.org/10.1371/journal.ppat.1009805

Intranasal immunization with peptide-based immunogenic complex enhances BCG vaccine efficacy in a murine model of tuberculosis
Kumar, S, Bhaskar, A, Patnaik, G, Sharma, C, Singh, DK, Kaushik, SR, Chaturvedi, S, Das, G & Dwivedi, VP 2021, , JCI insight, vol. 6, no. 4, e145228. https://doi.org/10.1172/jci.insight.145228

Pathogen induced subversion of NAD+ metabolism mediating host cell death: a target for development of chemotherapeutics
Chaurasiya, A, Garg, S, Khanna, A, Narayana, C, Dwivedi, VP, Joshi, N, e Anam, Z, Singh, N, Singhal, J, Kaushik, S, Kaur Kahlon, A, Srivastava, P, Marothia, M, Kumar, M, Kumar, S, Kumari, G, Munjal, A, Gupta, S, Singh, P, Pati, S, Das, G, Sagar, R, Ranganathan, A & Singh, S 2021, , Cell Death Discovery, vol. 7, no. 1, 10. https://doi.org/10.1038/s41420-020-00366-z

Luteolin-mediated kv1.3 k+ channel inhibition augments bcg vaccine efficacy against tuberculosis by promoting central memory t cell responses in mice
Singh, DK, Dwivedi, VP, Singh, SP, Kumari, A, Sharma, SK, Ranganathan, A, Kaer, LV & Das, G 2020, , PLoS pathogens, vol. 16, no. 9, e1008887. https://doi.org/10.1371/journal.ppat.1008887

BCG vaccination policy and preventive chloroquine usage: do they have an impact on COVID-19 pandemic?
Sharma, A, Kumar Sharma, S, Shi, Y, Bucci, E, Carafoli, E, Melino, G, Bhattacherjee, A & Das, G 2020, , Cell Death and Disease, vol. 11, no. 7, 516. https://doi.org/10.1038/s41419-020-2720-9

Tuberculosis vaccine: A journey from BCG to present
Fatima, S, Kumari, A, Das, G & Dwivedi, VP 2020, , Life sciences, vol. 252. https://doi.org/10.1016/j.lfs.2020.117594

Clofazimine enhances the efficacy of BCG revaccination via stem cell-like memory T cells
Ahmad, S, Bhattacharya, D, Gupta, N, Rawat, V, Tousif, S, van Kaer, L & Das, G 2020, , PLoS pathogens, vol. 16, no. 5, e1008356. https://doi.org/10.1371/journal.ppat.1008356

Mycobacterium tuberculosis programs mesenchymal stem cells to establish dormancy and persistence
Fatima, S, Kamble, SS, Dwivedi, VP, Bhattacharya, D, Kumar, S, Ranganathan, A, Van Kaer, L, Mohanty, S & Das, G 2020, , Journal of Clinical Investigation, vol. 130, no. 2, pp. 655-661. https://doi.org/10.1172/JCI128043

Allicin enhances antimicrobial activity of macrophages during Mycobacterium tuberculosis infection
Dwivedi, VP, Bhattacharya, D, Singh, M, Bhaskar, A, Kumar, S, Fatima, S, Sobia, P, Kaer, LV & Das, G 2019, , Journal of Ethnopharmacology, vol. 243, 111634. https://doi.org/10.1016/j.jep.2018.12.008

Mycobacterium indicus pranii therapy induces tumor regression in MyD88- and TLR2-dependent manner
Kumar, P, Das, G & Bhaskar, S 2019, , BMC Research Notes, vol. 12, no. 1, 648. https://doi.org/10.1186/s13104-019-4679-0

The phytochemical bergenin as an adjunct immunotherapy for tuberculosis in mice
Kumar, S, Sharma, C, Kaushik, SR, Kulshreshtha, A, Chaturvedi, S, Nanda, RK, Bhaskar, A, Chattopadhyay, D, Das, G & Dwivedi, VP 2019, , Journal of Biological Chemistry, vol. 294, no. 21, pp. 8555-8563. https://doi.org/10.1074/jbc.RA119.008005

Curcumin nanoparticles enhance mycobacterium bovis BCG vaccine efficacy by modulating host immune responses
Ahmad, S, Bhattacharya, D, Kar, S, Ranganathan, A, Van Kaer, L & Das, G 2019, , Infection and Immunity, vol. 87, no. 11, e00291-19. https://doi.org/10.1128/IAI.00291-19

Cellular architecture of spinal granulomas and the immunological response in tuberculosis patients coinfected with HIV
Bhattacharya, D, Danaviah, S, Muema, DM, Akilimali, NA, Moodley, P, Ndungu, T & Das, G 2017, , Frontiers in immunology, vol. 8, no. SEP, 1120. https://doi.org/10.3389/fimmu.2017.01120

Nanoparticle-formulated curcumin prevents posttherapeutic disease reactivation and reinfection with Mycobacterium tuberculosis following isoniazid therapy
Tousif, S, Singh, DK, Mukherjee, S, Ahmad, S, Arya, R, Nanda, R, Ranganathan, A, Bhattacharyya, M, Kaer, LV, Kar, SK & Das, G 2017, , Frontiers in immunology, vol. 8, no. JUN, 739. https://doi.org/10.3389/fimmu.2017.00739

The phytochemical bergenin enhances T helper 1 responses and anti-mycobacterial immunity by activating the MAP kinase pathway in macrophages
Dwivedi, VP, Bhattacharya, D, Yadav, V, Singh, DK, Kumar, S, Singh, M, Ojha, D, Ranganathan, A, Van Kaer, L, Chattopadhyay, D & Das, G 2017, , Frontiers in cellular and infection microbiology, vol. 7, no. MAY, 149. https://doi.org/10.3389/fcimb.2017.00149

Reply to Levis and Rendini
Singh, DK, Dwivedi, VP, Ranganathan, A, Bishai, WR, Kaer, LV & Das, G 2017, , Journal of Infectious Diseases, vol. 215, no. 9, pp. 1488-1489. https://doi.org/10.1093/infdis/jix084

Blockade of the Kv1.3 K+ Channel Enhances BCG Vaccine Efficacy by Expanding Central Memory T Lymphocytes
Singh, DK, Dwivedi, VP, Ranganathan, A, Bishai, WR, Van Kaer, L & Das, G 2016, , Journal of Infectious Diseases, vol. 214, no. 9, pp. 1456-1464. https://doi.org/10.1093/infdis/jiw395

Strategies to improve BCG vaccine efficacy
Bali, P, Tousif, S, Das, G & Van Kaer, L 2015, , Immunotherapy, vol. 7, no. 9, pp. 945-948. https://doi.org/10.2217/imt.15.60