George Taffet, MD

Adjunct Professor of Medicine, Institute for Academic Medicine
Houston Methodist
Weill Cornell Medical College


Education & Training

Residency, Baylor College of Medicine
Clinical Fellowship, Baylor College of Medicine
MD, Brown University Program in Medicine
Publications

Short-Term Global Cardiovascular Disease Risk Prediction in Older Adults
Saeed, A, Nambi, V, Sun, W, Virani, SS, Taffet, GE, Deswal, A, Selvin, E, Matsushita, K, Wagenknecht, LE, Hoogeveen, R, Coresh, J, de Lemos, JA & Ballantyne, CM 2018, Journal of the American College of Cardiology, vol 71, no. 22, pp. 2527-2536. DOI: 10.1016/j.jacc.2018.02.050

Prevalence of Cognitive Impairment Among Elderly Patients Upon Hospital Admission Using Mini-Cog™ Assessments Performed by Advanced Pharmacy Practice Experience Students
Bui, NA, Adeola, M, Azad, R, Swan, JT, Agarwal, KS, Sharma, M, Liebl, MG & Taffet, GE 2018, Journal of Pharmacy Practice. DOI: 10.1177/0897190018780591

Steroid Receptor Coactivator-2 (SRC-2) coordinates cardiomyocyte paracrine signaling to promote pressure overload-induced angiogenesis.
Suh, JH, Lai, L, Nam, D, Kim, J, Jo, J, Taffet, G, Kim, E, Kaelber, J, Lee, H, Entman, ML, Cooke, JP & Reineke, EL 2017, Journal of Biological Chemistry.

Cardiac Resynchronization Therapy in Older Adults with Heart Failure
Lam, PH, Taffet, GE, Ahmed, A & Singh, S 2017, Heart Failure Clinics, vol 13, no. 3, pp. 581-587. DOI: 10.1016/j.hfc.2017.02.011

Dissecting the role of myeloid and mesenchymal fibroblasts in age-dependent cardiac fibrosis
Trial, JA, Heredia, CP, Taffet, GE, Entman, ML & Cieslik, KA 2017, Basic Research in Cardiology, vol 112, no. 4, 34. DOI: 10.1007/s00395-017-0623-4

Murine echocardiography of left atrium, aorta, and pulmonary artery
Granillo, A, Pena, CA, Pham, T, Pandit, LM & Taffet, GE 2017, Journal of Visualized Experiments, vol 2017, no. 120, e55214. DOI: 10.3791/55214

Steroid receptor coactivator-2 (SRC-2) coordinates cardiomyocyte paracrine signaling to promote pressure overload-induced angiogenesis
Suh, JH, Lai, L, Nam, D, Kim, J, Jo, J, Taffet, GE, Kim, E, Kaelber, JT, Lee, HK, Entman, ML, Cooke, JP & Reineke, EL 2017, Journal of Biological Chemistry, vol 292, no. 52, pp. 21643-21652. DOI: 10.1074/jbc.M117.804740

Unrecognized Cognitive Impairment and Its Effect on Heart Failure Readmissions of Elderly Adults
Agarwal, KS, Kazim, R, Xu, J, Borson, S & Taffet, GE 2016, Journal of the American Geriatrics Society, vol 64, no. 11, pp. 2296-2301. DOI: 10.1111/jgs.14471

Left atrial volume and pulmonary artery diameter are noninvasive measures of age-related diastolic dysfunction in mice
Medrano, G, Hermosillo-Rodriguez, J, Pham, T, Granillo, A, Hartley, CJ, Reddy, A, Osuna, PM, Entman, ML & Taffet, GE 2016, Journals of Gerontology - Series A Biological Sciences and Medical Sciences, vol 71, no. 9, pp. 1141-1150. DOI: 10.1093/gerona/glv143

TNF/Ang-II synergy is obligate for fibroinflammatory pathology, but not for changes in cardiorenal function
Mayr, M, Duerrschmid, C, Medrano, G, Taffet, GE, Wang, Y, Entman, ML & Haudek, SB 2016, Physiological Reports, vol 4, no. 8, e12765. DOI: 10.14814/phy2.12765

Measures of healthspan as indices of aging in Mice-A recommendation
Richardson, A, Fischer, KE, Speakman, JR, De Cabo, R, Mitchell, SJ, Peterson, CA, Rabinovitch, P, Chiao, YA, Taffet, G, Miller, RA, Rentería, RC, Bower, J, Ingram, DK, Ladiges, WC, Ikeno, Y, Sierra, F & Austad, SN 2016, Journals of Gerontology - Series A Biological Sciences and Medical Sciences, vol 71, no. 4, pp. 427-430. DOI: 10.1093/gerona/glv080

Plasma Levels of Endothelial Microparticles Bearing Monomeric C-reactive Protein are Increased in Peripheral Artery Disease
Crawford, JR, Trial, J, Nambi, V, Hoogeveen, RC, Taffet, GE & Entman, ML 2016, Journal of Cardiovascular Translational Research, pp. 1-10. DOI: 10.1007/s12265-016-9678-0

Prognostic significance of anaemia in patients with heart failure with preserved and reduced ejection fraction: Results from the MAGGIC individual patient data meta-analysis
Berry, C, Poppe, KK, Gamble, GD, Earle, NJ, Ezekowitz, JA, Squire, IB, McMurray, JJV, McAlister, FA, Komajda, M, Swedberg, K, Maggioni, AP, Ahmed, A, Whalley, GA, Doughty, RN, Tarantini, L, Granger, C, Køber, L, Massie, B, Pocock, S, Somaratne, J, Andersson, B, Bayes-Genis, A, Cowie, M, Cubbon, R, Gonzalez-Juanatey, J, Gorini, M, Gotsman, I, Grigorian-Shamagian, L, Guazzi, M, Kearney, M, Di Lenarda, A, Lenzen, M, Lucci, D, Macín, S, Madsen, B, Martínez-Sellés, M, Oliva, F, Rich, M, Richards, M, Senni, M, Taffet, G, Tribouilloy, C, Troughton, R, Tsutsui, H, Ariti, C, Dobson, J, Hall, C, Lainchbury, J, Hogg, K, Norrie, J, Stevenson, K, Brett, M, Pfeffer, MA, Held, P, Michelson, EL, Olofsson, B, Östergren, J, Yusuf, S, Torp-Pedersen, C, Scholte op Reimer, W, Boersma, E, Vantrimpont, PJMJ, Follath, F, Cleland, J, Zwas, D, Planer, D, Azaz-Livshits, T, Admon, D, Lotan, C, Keren, A, Varela-Roman, A, Mazón-Ramos, P, Rigeiro-Veloso, P, Bandin-Dieguez, MA, Myers, J, Arena, R, Armstrong, PW, Cujec, B, Paterson, I, Wood, DA, Coats, AJS, Thompson, SG, Suresh, V, Poole-Wilson, PA, Sutton, GC, Robles, JAG, Prieto, L, Muñoa, MD, Frades, E, Díaz-Castro, O, Almendral, J, Faggiano, P, Bertoli, D, Porcu, M, Opasich, C, Tavazzi, L, Kirk, V, Bay, M, Parner, J, Krogsgaard, K, Herzog, TM, Boesgaard, S, Hassager, C, Nielsen, OW, Aldershvile, J, Nielsen, H, Kober, L, Perna, ER, Cimbaro Canella, JP, Alvarenga, P, Pantich, R, Ríos, N, Farias, EF, Badaracco, JR, Hansen, JF, Stokholm, KH, Brons, J, Husum, D, Mortensen, LS, Vazquez, R, Puig, T, Fernandez-Palomeque, C, Bardají, A, Pascual-Figal, D, Ordoñez-Llanos, J, Valdes, M, Gabarrus, A, Pavon, R, Pastor, L, Fiol, M, Nieto, V, Macaya, C, Cinca, J, Cygankiewitz, I, Bayes De Luna, A, Newton, JD, Blackledge, HM, Wright, SP, Kerzner, R, Gage, BF, Freedland, KE, Huynh, BC, Rovner, A, Carney, RM, Teasdale, TA, Bleyer, AJ, Kutka, NJ, Luchi, RJ, Rusinaru, D, Mahjoub, H, Soulière, V, Lévy, F, Peltier, M, Tsuchihashi, M, Takeshita, A, MacCarthy, PA, Nolan, J, Lee, AJ, Prescott, RJ, Shah, AM, Brooksby, WP, Fox, KAA, Basante, P, Trillo, R, Garcia-Seara, J, Martinez-Sande, JL & Gude, F 2016, QJM, vol 109, no. 6, pp. 377-382. DOI: 10.1093/qjmed/hcv087

PHD2/3-dependent hydroxylation tunes cardiac response to ß-adrenergic stress via phospholamban
Xie, L, Pi, X, Townley-Tilson, WHD, Li, N, Wehrens, XHT, Entman, ML, Taffet, GE, Mishra, A, Peng, J, Schisler, JC, Meissner, G & Patterson, C 2015, Journal of Clinical Investigation, vol 125, no. 7, pp. 2759-2771. DOI: 10.1172/JCI80369

Heart failure with preserved ejection fraction in the elderly: Scope of the problem
Upadhya, B, Taffet, GE, Cheng, CP & Kitzman, DW 2015, Journal of Molecular and Cellular Cardiology, vol 83, pp. 73-87. DOI: 10.1016/j.yjmcc.2015.02.025

Cardiovascular physiology in the older adults
Dai, X, Hummel, SL, Salazar, JB, Taffet, GE, Zieman, S & Schwartz, JB 2015, Journal of Geriatric Cardiology, vol 12, no. 3, pp. 196-201. DOI: 10.11909/j.issn.1671-5411.2015.03.015

Substance P receptor antagonism: A potential novel treatment option for viral-myocarditis
Robinson, P, Taffet, GE, Engineer, N, Khumbatta, M, Firozgary, B, Reynolds, C, Pham, T, Bulsara, T & Firozgary, G 2015, BioMed Research International, vol 2015, 645153. DOI: 10.1155/2015/645153

High-Sensitivity troponin t and cardiovascular events in systolic blood pressure categories atherosclerosis risk in communities study
Pokharel, Y, Sun, W, De Lemos, JA, Taffet, GE, Virani, SS, Ndumele, CE, Mosley, TH, Hoogeveen, RC, Coresh, J, Wright, JD, Heiss, G, Boerwinkle, EA, Bozkurt, B, Solomon, SD, Ballantyne, CM & Nambi, V 2015, Hypertension, vol 65, no. 1, pp. 78-84. DOI: 10.1161/HYPERTENSIONAHA.114.04206

Hypernatremia in the geriatric population
Shah, MK, Workeneh, B & Taffet, GE 2014, Clinical Interventions in Aging, vol 9, pp. 1987-1992. DOI: 10.2147/CIA.S65214

Vascular and parenchymal amyloid pathology in an Alzheimer disease knock-in mouse model: Interplay with cerebral blood flow
Li, H, Guo, Q, Inoue, T, Polito, VA, Tabuchi, K, Hammer, RE, Pautler, RG, Taffet, GE & Zheng, H 2014, Molecular Neurodegeneration, vol 9, no. 1, 28. DOI: 10.1186/1750-1326-9-28