Fen Wang, PhD

Adjunct Professor of Oncology, Academic Institute
Adjunct Professor of Surgery, Academic Institute
Houston Methodist


Acetyl-CoA carboxylase 1 depletion suppresses de novo fatty acid synthesis and mitochondrial Ăź-oxidation in castration-resistant prostate cancer cells
Liu, S, Lai, J, Feng, Y, Zhuo, Y, Zhang, H, Chen, Y, Li, J, Mei, X, Zeng, Y, Su, J, Deng, Y, Jiang, F, Yang, S, Tan, H, Hon, CT, Wei, S, Han, Z, Wang, F & Zhong, W 2023, , Journal of Biological Chemistry, vol. 299, no. 1, 102720, pp. 102720. https://doi.org/10.1016/j.jbc.2022.102720

Indole supplementation ameliorates MCD-induced NASH in mice
Zhu, B, Li, H, Lu, B, Guo, X, Wu, C, Wang, F, Li, Q, Xie, L, Glaser, S, Francis, H, Alpini, G & Wu, C 2022, , Journal of Nutritional Biochemistry, vol. 107, 109041, pp. 109041. https://doi.org/10.1016/j.jnutbio.2022.109041

Crosstalk of FGFR1 signaling and choline metabolism promotes cell proliferation and survival in prostate cancer cells
Fan, Z, Ma, J, Pan, X, Zhao, L, Wu, Y, Lin, H, Zhao, Y, Jiang, H, Pan, T, Li, X, Wang, F & Wang, C 2022, , International Journal of Cancer, vol. 150, no. 9, pp. 1525-1536. https://doi.org/10.1002/ijc.33922

Steroid-induced fibroblast growth factors drive an epithelial-mesenchymal inflammatory axis in severe asthma
Guidi, R, Xu, D, Choy, DF, Ramalingam, TR, Lee, WP, Modrusan, Z, Liang, Y, Marsters, S, Ashkenazi, A, Huynh, A, Mills, J, Flanagan, S, Hambro, S, Nunez, V, Leong, L, Cook, A, Tran, TH, Austin, CD, Cao, Y, Clarke, C, Panettieri, RA, Koziol-White, C, Jester, WF, Wang, F & Wilson, MS 2022, , Science translational medicine, vol. 14, no. 641, eabl8146, pp. eabl8146. https://doi.org/10.1126/scitranslmed.abl8146

Phase transition specified by a binary code patterns the vertebrate eye cup
Balasubramanian, R, Min, X, Quinn, PMJ, Giudice, QL, Tao, C, Polanco, K, Makrides, N, Peregrin, J, Bouaziz, M, Mao, Y, Wang, Q, da Costa, BL, Buenaventura, D, Wang, F, Ma, L, Tsang, SH, Fabre, PJ & Zhang, X 2021, , Science Advances, vol. 7, no. 46, eabj9846. https://doi.org/10.1126/sciadv.abj9846

Targeted Inhibition of Fibroblast Growth Factor Receptor 1-GLI Through AZD4547 and GANT61 Modulates Breast Cancer Progression
Riaz, SK, Khan, W, Wang, F, Khaliq, T, Malik, A, Razia, ET, Khan, JS, Haque, S, Hashem, AM, Alkhayyat, SS, Azhar, NE, Harakeh, S, Ansari, MJ, Haq, F & Malik, MFA 2021, , Frontiers in Cell and Developmental Biology, vol. 9, 758400. https://doi.org/10.3389/fcell.2021.758400

Structure and function of DEAH-box helicase 32 and its role in cancer (Review)
Wei, Q, Geng, J, Chen, Y, Lin, H, Wang, J, Fang, Z, Wang, F & Zhang, Z 2021, , Oncology Letters, vol. 21, no. 5, 382. https://doi.org/10.3892/OL.2021.12643

Regulation of PD-L1 expression in K-ras-driven cancers through ROS-mediated FGFR1 signaling
Glorieux, C, Xia, X, He, YQ, Hu, Y, Cremer, K, Robert, A, Liu, J, Wang, F, Ling, J, Chiao, PJ & Huang, P 2021, , Redox Biology, vol. 38, 101780. https://doi.org/10.1016/j.redox.2020.101780

Editorial: Resident and Ectopic FGF Signaling in Development and Disease
Wang, F, Li, X & Wang, C 2020, , Frontiers in Cell and Developmental Biology, vol. 8, 720, pp. 720. https://doi.org/10.3389/fcell.2020.00720

ARNT-dependent CCR8 reprogrammed LDH isoform expression correlates with poor clinical outcomes of prostate cancer
Chen, G, Cai, ZD, Lin, ZY, Wang, C, Liang, YX, Han, ZD, He, HC, Mo, RJ, Lu, JM, Pan, B, Wu, CL, Wang, F & Zhong, WD 2020, , Molecular Carcinogenesis, vol. 59, no. 8, pp. 897-907. https://doi.org/10.1002/mc.23201

Fibroblast growth factors signaling in bone metastasis
Labanca, E, Vazquez, ES, Corn, PG, Roberts, JM, Wang, F, Logothetis, CJ & Navone, NM 2020, , Endocrine-Related Cancer, vol. 27, no. 7, pp. R255-R265. https://doi.org/10.1530/ERC-19-0472

LRPPRC sustains Yap-P27-mediated cell ploidy and P62-HDAC6-mediated autophagy maturation and suppresses genome instability and hepatocellular carcinomas
Li, W, Dai, Y, Shi, B, Yue, F, Zou, J, Xu, G, Jiang, X, Wang, F, Zhou, X & Liu, L 2020, , Oncogene, vol. 39, no. 19, pp. 3879-3892. https://doi.org/10.1038/s41388-020-1257-9

P62 promotes proliferation, apoptosis–resistance and invasion of prostate cancer cells through the Keap1/Nrf2/ARE axis
Jiang, G, Liang, X, Huang, Y, Lan, Z, Zhang, Z, Su, Z, Fang, Z, Lai, Y, Yao, W, Liu, T, Hu, L, Wang, F, Huang, H, Liu, L & Jiang, X 2020, , Oncology Reports, vol. 43, no. 5, pp. 1547-1557. https://doi.org/10.3892/or.2020.7527

Caffeine-Operated Synthetic Modules for Chemogenetic Control of Protein Activities by Life Style
Wang, T, He, L, Jing, J, Lan, TH, Hong, T, Wang, F, Huang, Y, Ma, G & Zhou, Y 2021, , Advanced Science, vol. 8, no. 3, 2002148, pp. 2002148. https://doi.org/10.1002/advs.202002148

Tet inactivation disrupts YY1 binding and long-range chromatin interactions during embryonic heart development
Fang, S, Li, J, Xiao, Y, Lee, M, Guo, L, Han, W, Li, T, Hill, MC, Hong, T, Mo, W, Xu, R, Zhang, P, Wang, F, Chang, J, Zhou, Y, Sun, D, Martin, JF & Huang, Y 2019, , Nature Communications, vol. 10, no. 1, 4297. https://doi.org/10.1038/s41467-019-12325-z

Influence of SHH/GLI1 axis on EMT mediated migration and invasion of breast cancer cells
Riaz, SK, Ke, Y, Wang, F, Kayani, MA & Malik, MFA 2019, , Scientific Reports, vol. 9, no. 1, 6620. https://doi.org/10.1038/s41598-019-43093-x

FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis
Ji, S, Liu, Q, Zhang, S, Chen, Q, Wang, C, Zhang, W, Xiao, C, Li, Y, Nian, C, Li, J, Li, J, Geng, J, Hong, L, Xie, C, He, Y, Chen, X, Li, X, Yin, ZY, You, H, Lin, KH, Wu, Q, Yu, C, Johnson, RL, Wang, L, Chen, L, Wang, F & Zhou, D 2019, , Developmental Cell, vol. 48, no. 4, pp. 460-474.e9. https://doi.org/10.1016/j.devcel.2018.12.021

High serum levels of FGF21 are decreased in bipolar mania patients during psychotropic medication treatment and are associated with increased metabolism disturbance
Hu, Q, Wang, C, Liu, F, He, J, Wang, F, Wang, W & You, P 2019, , Psychiatry Research, vol. 272, pp. 643-648. https://doi.org/10.1016/j.psychres.2018.12.159

Lens differentiation is controlled by the balance between PDGF and FGF signaling
Li, H, Mao, Y, Bouaziz, M, Yu, H, Qu, X, Wang, F, Feng, GS, Shawber, C & Zhang, X 2019, , PLoS biology, vol. 17, no. 2, e3000133. https://doi.org/10.1371/journal.pbio.3000133

Intrinsic FGFR2 and ectopic FGFR1 signaling in the prostate and prostate cancer
Wang, C, Liu, Z, Ke, Y & Wang, F 2019, , Frontiers in Genetics, vol. 10, no. JAN, 12. https://doi.org/10.3389/fgene.2019.00012