Fazle Hussain

Fazle Hussain, PhD


Houston Methodist


Biography

Dr. Fazle Hussain is the Cullen Distinguished Professor and director of the Institute of Fluid Dynamics and Turbulence, in the mechanical engineering department at The University of Houston. Dr. Hussain is a world-renowned scientist in fluid dynamics with over 200 papers in prestigious journals. He has been a visiting scholar at Cambridge six times, the Indian Institute of Science at Bangalore, the Institute of Mechanics at Beijing, the Kavli Institute of Theoretical Physics at UCSB, and is the lifetime Moore Distinguished Scholar at Caltech and an honorary professor at Peking University.

Dr. Hussain currently serves on the board of The Academy of Medicine, Engineering and Science of Texas, as the mechanical engineering chair of the National Academy of Engineering, and as chair of the Academy of Science of the Developing World. He is a Fellow of APS, the American Society of Mechanical Engineers, and the American Institute of Aeronautics and Astronautics.

Dr. Hussain has received awards including the Freeman Scholar Award of ASME in 1984, the Fluid Dynamics Prize of APS in 1998, the Fluids Engineering Award of ASME in 2000, and the Fluid Dynamics Award of AIAA in 2002 for his groundbreaking work in fluid dynamics. Dr. Hussain is a member of the National Academy of Engineering.

At Houston Methodist Research Institute, Dr. Hussain serves as the Dean of Engineering of the Council of Deans. In this capacity, he provides leadership, guidance and counsel for research and education.

Description of Research

The primary theme of Dr. Hussain’s research is the search for order in the disorder of turbulence. That is, underlying the complicated, seemingly random motion of turbulence, there is an organization. Dr. Hussain was one of the pioneers in recognizing that such organized motion is the key to understanding turbulence, and to controlling turbulent flows for technological benefit. For example, to design better engines and turbines, reduce drag and hence saving fuel in aircraft, and reduce the noise from jet engines. For applications like these and more, he has pursued experimental, numerical and theoretical studies of the basic mechanisms of turbulence.

Areas Of Expertise

Fluid mechanics Turbulent flows Vortex dynamics Jets and boundary layers Aeroacoustics Optical measurement techniques Fluidized beds Bio-fluid dynamics
Education & Training

MSc, Stanford University
PhD, Stanford University
Publications

Mitigation of Breast Cancer Cells’ Invasiveness via Down Regulation of ETV7, Hippo, and PI3K/mTOR Pathways by Vitamin D3 Gold-Nanoparticles
Roy, M & Hussain, F 2024, , International journal of molecular sciences, vol. 25, no. 10, 5348. https://doi.org/10.3390/ijms25105348

Karhunen-Loéve decomposition of high Reynolds number turbulent pipe flows: A Voronoi analysis
Massaro, D, Yao, J, Rezaeiravesh, S, Hussain, F & Schlatter, P 2024, , Journal of Physics: Conference Series, vol. 2753, no. 1, 012018. https://doi.org/10.1088/1742-6596/2753/1/012018

Curbing Breast Cancer by Altering V-ATPase Action on F-Actin, Heterochromatin, ETV7 and mTORC2 Signaling
Khan, ZS & Hussain, F 2024, , Cellular Physiology and Biochemistry, vol. 58, no. 3, pp. 250-272. https://doi.org/10.33594/000000706

Vorticity dynamics in transcritical liquid jet breakup
Poblador-Ibanez, J, Sirignano, WA & Hussain, F 2023, , Journal of Fluid Mechanics, vol. 978, A6. https://doi.org/10.1017/jfm.2023.961

Role of internal structures within a vortex in helicity dynamics
Shen, W, Yao, J, Hussain, F & Yang, Y 2023, , Journal of Fluid Mechanics, vol. 970, A26. https://doi.org/10.1017/jfm.2023.620

Coherent structure-turbulence interaction studied via a vortex column embedded in fine-scale turbulence
Stout, E & Hussain, F 2023, , Sadhana - Academy Proceedings in Engineering Sciences, vol. 48, no. 3, 159. https://doi.org/10.1007/s12046-023-02187-z

Study of compressible turbulent plane Couette flows via direct numerical simulation
Yao, J & Hussain, F 2023, , Journal of Fluid Mechanics, vol. 964, A29. https://doi.org/10.1017/jfm.2023.359

A High Dose of Calcitriol Inhibits Glycolysis and M2 Macrophage Polarization in the Tumor Microenvironment by Repressing mTOR Activation: in vitro and Molecular Docking Studies
Munir, MT, Halim, SA, Santos, JM, Khan, F, Khan, A, Rahman, MM, Hussain, F, Al-Harrasi, A, Gollahon, LS & Rahman, SM 2023, , Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, vol. 57, no. 2, pp. 105-122. https://doi.org/10.33594/000000618

Direct numerical simulations of turbulent pipe flow up to
Yao, J, Rezaeiravesh, S, Schlatter, P & Hussain, F 2023, , Journal of Fluid Mechanics, vol. 956, A18. https://doi.org/10.1017/jfm.2022.1013

Direct numerical simulation of turbulent open channel flows at moderately high Reynolds numbers
Yao, J, Chen, X & Hussain, F 2022, , Journal of Fluid Mechanics, vol. 953, A19. https://doi.org/10.1017/jfm.2022.942

Experimental characterization of smooth body flow separation topography and topology on a two-dimensional geometry of finite span
Simmons, DJ, Thomas, FO, Corke, TC & Hussain, F 2022, , Journal of Fluid Mechanics, vol. 944, A42. https://doi.org/10.1017/jfm.2022.465

Helicity dynamics in viscous vortex links
Yao, J, Shen, W, Yang, Y & Hussain, F 2022, , Journal of Fluid Mechanics, vol. 944, A41. https://doi.org/10.1017/jfm.2022.532

The United States COVID-19 Forecast Hub dataset
US COVID-19 Forecast Hub Consortium 2022, , Scientific Data, vol. 9, no. 1, 462, pp. 462. https://doi.org/10.1038/s41597-022-01517-w

Modeling the change in European and US COVID-19 death rates
Khan, ZS, Van Bussel, F & Hussain, F 2022, , PLoS ONE, vol. 17, no. 8, e0268332, pp. e0268332. https://doi.org/10.1371/journal.pone.0268332

Topological transition and helicity conversion of vortex knots and links
Shen, W, Yao, J, Hussain, F & Yang, Y 2022, , Journal of Fluid Mechanics, vol. 943, A41. https://doi.org/10.1017/jfm.2022.464

Parthenolide reverses the epithelial to mesenchymal transition process in breast cancer by targeting TGFbeta1: In vitro and in silico studies
Sufian, HB, Santos, JM, Khan, ZS, Halim, SA, Khan, A, Munir, MT, Zahid, MDK, Al-Harrasi, A, Gollahon, LS, Hussain, F & Rahman, SM 2022, , Life sciences, vol. 301, 120610, pp. 120610. https://doi.org/10.1016/j.lfs.2022.120610

Roles of Tidal Cycling, Hyporheic Exchange and Bioirrigation on Metal Release From Estuary Sediments
Liu, Y, Reible, D & Hussain, F 2022, , Water Resources Research, vol. 58, no. 4, e2021WR030790. https://doi.org/10.1029/2021WR030790

Sound generation mechanism of compressible vortex reconnection
Daryan, H, Hussain, F & Hickey, JP 2022, , Journal of Fluid Mechanics, vol. 933, A34. https://doi.org/10.1017/jfm.2021.1088

Strong Scaling of OpenACC enabled Nek5000 on several GPU based HPC systems
Vincent, J, Gong, J, Karp, M, Peplinski, A, Jansson, N, Podobas, A, Jocksch, A, Yao, J, Hussain, F, Markidis, S, Karlsson, M, Pleiter, D, Laure, E & Schlatter, P 2022, . in Proceedings of International Conference on High Performance Computing in Asia-Pacific Region, HPC Asia 2022. ACM International Conference Proceeding Series, Association for Computing Machinery, pp. 94-102, 5th International Conference on High Performance Computing in Asia-Pacific Region, HPC Asia 2022, Virtual, Online, Japan, 1/12/22. https://doi.org/10.1145/3492805.3492818

ESTIMATING UNCERTAINTY OF LOW- AND HIGH-ORDER TURBULENCE STATISTICS IN WALL TURBULENCE
Rezaeiravesh, S, Xavier, D, Vinuesa, R, Yao, J, Hussain, F & Schlatter, P 2022, , Paper presented at 12th International Symposium on Turbulence and Shear Flow Phenomena, TSFP 2022, Osaka, Virtual, Japan, 7/19/22 - 7/22/22.