Eugene J. Koay

Eugene J. Koay, MD, PhD

Assistant Affiliate Member, Research Institute
Houston Methodist


Publications

Machine learning identifies prognostic subtypes of the tumor microenvironment of NSCLC
Yu, D, Kane, MJ, Koay, EJ, Wistuba, II & Hobbs, BP 2024, , Scientific Reports, vol. 14, no. 1, 15004. https://doi.org/10.1038/s41598-024-64977-7

Translational modeling-based evidence for enhanced efficacy of standard-of-care drugs in combination with anti-microRNA-155 in non-small-cell lung cancer
Dogra, P, Shinglot, V, Ruiz-Ramírez, J, Cave, J, Butner, JD, Schiavone, C, Duda, DG, Kaseb, AO, Chung, C, Koay, EJ, Cristini, V, Ozpolat, B, Calin, GA & Wang, Z 2024, , Molecular Cancer, vol. 23, no. 1, 156. https://doi.org/10.1186/s12943-024-02060-5

Development and clinical implementation of a digital workflow utilizing 3D-printed oral stents for patients with head and neck cancer receiving radiotherapy
Tino, R, Roach, MA, Fuentes, GD, Agrawal, A, Zaid, M, Cooper, DJ, Bajaj, N, Lin, R, Xiao, L, Mayo, LL, Wiederhold, LR, Shah, SJ, Tate, MK, Chronowski, GM, Reddy, JP, Mezera, M, Mann, JM, Augspurger, M, Otun, AO, Chambers, MS & Koay, EJ 2024, , Oral Oncology, vol. 157, 106944. https://doi.org/10.1016/j.oraloncology.2024.106944

Hybridizing mechanistic modeling and deep learning for personalized survival prediction after immune checkpoint inhibitor immunotherapy
Butner, JD, Dogra, P, Chung, C, Koay, EJ, Welsh, JW, Hong, DS, Cristini, V & Wang, Z 2024, , npj Systems Biology and Applications, vol. 10, no. 1, 88, pp. 88. https://doi.org/10.1038/s41540-024-00415-8

Translational modeling-based evidence for enhanced efficacy of standard-of-care drugs in combination with anti-microRNA-155 in non-small-cell lung cancer
Dogra, P, Shinglot, V, Ruiz-Ramírez, J, Cave, J, Butner, JD, Schiavone, C, Duda, DG, Kaseb, AO, Chung, C, Koay, EJ, Cristini, V, Ozpolat, B, Calin, GA & Wang, Z 2024, , Molecular Cancer, vol. 23, no. 1, pp. 156. https://doi.org/10.1186/s12943-024-02060-5

Clinical Validation of Mathematically Derived Early Tumor Dynamics for Solid Tumors in Response to Durvalumab
Li, Q, Cristini, V, Gupta, A, Achour, I, Barrett, JC & Koay, EJ 2024, , JCO clinical cancer informatics, vol. 8, 00074, pp. e2300254. https://doi.org/10.1200/CCI.23.00254

Development of a Novel Comprehensive Hepatocellular Carcinoma Outcome Prognostic Scoring System With Integration of Imaging Features
Tran Cao, HS, Witt, RG, Elsayes, KM, Baiomy, AA, Xiao, L, Palmquist, S, Lee, SS, Mohamed, YI, Mahvash, A, Tzeng, CWD, Chun, YS, Koay, EJ, Rashid, A, Hassan, MM, Yao, JC, Vauthey, JN & Kaseb, AO 2024, , Oncologist, vol. 29, no. 6, pp. e803-e810. https://doi.org/10.1093/oncolo/oyad329

Escalated-dose radiotherapy for unresected locally advanced pancreatic cancer: Patterns of care and survival in the United States
Shi, C, De, B, Tran Cao, HS, Liu, S, Florez, MA, Kouzy, R, Grippin, AJ, Katz, MHG, Tzeng, CWD, Ikoma, N, Kim, MP, Lee, S, Willis, J, Noticewala, SS, Minsky, BD, Smith, GL, Holliday, EB, Taniguchi, CM, Koong, AC, Das, P, Ludmir, EB & Koay, EJ 2024, , Cancer Medicine, vol. 13, no. 12, e7434, pp. e7434. https://doi.org/10.1002/cam4.7434

Phase i trial of single-photon emission computed tomography-guided liver-directed radiotherapy for patients with low functional liver volume
Chang, E, Wong, FCL, Chasen, BA, Erwin, WD, Das, P, Holliday, EB, Koong, AC, Ludmir, EB, Minsky, BD, Noticewala, SS, Smith, GL, Taniguchi, CM, Rodriguez, MJ, Beddar, S, Martin-Paulpeter, RM, Niedzielski, JS, Sawakuchi, GO, Schueler, E, Perles, LA, Xiao, L, Szklaruk, J, Park, PC, Dasari, AN, Kaseb, AO, Kee, BK, Lee, SS, Overman, MJ, Willis, JA, Wolff, RA, Tzeng, CWD, Vauthey, JN & Koay, EJ 2024, , JNCI Cancer Spectrum, vol. 8, no. 3, pkae037. https://doi.org/10.1093/jncics/pkae037

OSLD nanoDot characterization for carbon radiotherapy dosimetry
Taylor, PA, Hartzell, S, Mirandola, A, Ciocca, M, Magro, G, Alvarez, P, Peterson, CB, Peeler, CR, Koay, EJ, Howell, RM & Kry, SF 2024, , Physics in Medicine and Biology, vol. 69, no. 11, 115001. https://doi.org/10.1088/1361-6560/ad43ac

Long-Term Patient-Reported Dyspareunia After Definitive Chemoradiation for Anal Cancer: Using the Anterior Vaginal Wall as an Organ-at-Risk to Define an Actionable Dosimetric Goal
Rooney, MK, Niedzielski, JS, Salazar, RM, Arzola, A, Das, P, Koay, EJ, Koong, A, Ludmir, EB, Minsky, BD, Noticewala, S, Smith, GL, Taniguchi, C & Holliday, EB 2024, , Advances in Radiation Oncology, vol. 9, no. 5, 101449, pp. 101449. https://doi.org/10.1016/j.adro.2024.101449

Postprogression therapy and confounding for the estimated treatment effect on overall survival in phase III oncology trials
Sherry, AD, Msaouel, P, Lin, TA, Abi Jaoude, J, Kouzy, R, Beck, EJ, Miller, AM, Passy, AH, Kupferman, GS, Koay, EJ, Fuller, CD, Thomas, CR, McCaw, ZR & Ludmir, EB 2024, , BMJ Oncology, vol. 3, no. 1, e000322. https://doi.org/10.1136/bmjonc-2024-000322

Hybridizing mechanistic mathematical modeling with deep learning methods to predict individual cancer patient survival after immune checkpoint inhibitor therapy
Butner, J, Dogra, P, Chung, C, Koay, E, Welsh, J, Hong, D, Cristini, V & Wang, Z 2024, , Research square. https://doi.org/10.21203/rs.3.rs-4151883/v1

Translational modeling-based evidence for enhanced efficacy of standard-of-care drugs in combination with anti-microRNA-155 in non-small-cell lung cancer
Dogra, P, Shinglot, V, Ruiz-Ramírez, J, Cave, J, Butner, JD, Schiavone, C, Duda, DG, Kaseb, AO, Chung, C, Koay, EJ, Cristini, V, Ozpolat, B, Calin, GA & Wang, Z 2024, , medRxiv. https://doi.org/10.1101/2024.03.14.24304306

Daily Vaginal Dilator Use During Radiation for Women With Squamous Cell Carcinoma of the Anus: Vaginal Wall Dosimetry and Patient-Reported Sexual Function
Arzola, A, Chang, E, Rooney, MK, Corrigan, K, Das, P, Ludmir, EB, Koay, EJ, Minsky, BD, Smith, GL, Messick, C, Morris, VK, Nebgen, D, Crane, CH & Holliday, EB 2024, , Practical Radiation Oncology, vol. 14, no. 2, pp. e105-e116. https://doi.org/10.1016/j.prro.2023.10.002

Defining Minimum Treatment Parameters of Ablative Radiation Therapy in Patients With Hepatocellular Carcinoma: An Expert Consensus
Yanagihara, TK, Tepper, JE, Moon, AM, Barry, A, Molla, M, Seong, J, Torres, F, Apisarnthanarax, S, Buckstein, M, Cardenes, H, Chang, DT, Feng, M, Guha, C, Hallemeier, CL, Hawkins, MA, Hoyer, M, Iwata, H, Jabbour, SK, Kachnic, L, Kharofa, J, Kim, TH, Kirichenko, A, Koay, EJ, Makishima, H, Mases, J, Meyer, JJ, Munoz-Schuffenegger, P, Owen, D, Park, HC, Saez, J, Sanford, NN, Scorsetti, M, Smith, GL, Wo, JY, Yoon, SM, Lawrence, TS, Reig, M & Dawson, LA 2024, , Practical Radiation Oncology, vol. 14, no. 2, pp. 134-145. https://doi.org/10.1016/j.prro.2023.08.016

Fully automated deep learning based auto-contouring of liver segments and spleen on contrast-enhanced CT images
Gupta, AC, Cazoulat, G, Al Taie, M, Yedururi, S, Rigaud, B, Castelo, A, Wood, J, Yu, C, O’Connor, C, Salem, U, Silva, JAM, Jones, AK, McCulloch, M, Odisio, BC, Koay, EJ & Brock, KK 2024, , Scientific Reports, vol. 14, no. 1, 4678, pp. 4678. https://doi.org/10.1038/s41598-024-53997-y

Enhancement Pattern Mapping for Early Detection of Hepatocellular Carcinoma in Patients with Cirrhosis
Nikzad, N, Fuentes, DT, Roach, M, Chowdhury, T, Cagley, M, Badawy, M, Elkhesen, A, Hassan, M, Elsayes, K, Beretta, L, Koay, EJ & Jalal, PK 2024, , Journal of Hepatocellular Carcinoma, vol. 11, pp. 595-606. https://doi.org/10.2147/JHC.S449996

A Multi-Institutional Safety and Feasibility Study Exploring the Use of Hydrogel to Create Spatial Separation between the Pancreas and Duodenum in Patients with Pancreatic Cancer
Narang, AK, Hong, TS, Ding, K, Herman, J, Meyer, J, Thompson, E, Bhutani, MS, Krishnan, K, Casey, B, Shin, EJ & Koay, EJ 2024, , Practical Radiation Oncology, vol. 14, no. 4, pp. e276-e282. https://doi.org/10.1016/j.prro.2023.11.011

Technical note: Radiological clinical equivalence for phantom materials in carbon ion therapy
Taylor, PA, Mirandola, A, Ciocca, M, Hartzell, S, Vai, A, Alvarez, P, Howell, RM, Koay, EJ, Peeler, CR, Peterson, CB & Kry, SF 2024, , Medical Physics, vol. 51, no. 7, pp. 5154-5158. https://doi.org/10.1002/mp.17056