Emmanuel Yih Chang, MD, PhD

Adjunct Assistant Professor of Ophthalmology, Academic Institute
Assistant Affiliate Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Consensus Guidelines for Ocular Surveillance of von Hippel-Lindau Disease
Daniels, AB, Chang, EY, Chew, EY, Gombos, DS, Gorin, MB, Shields, CL & Wiley, HE 2024, , Ophthalmology, vol. 131, no. 5, pp. 622-633. https://doi.org/10.1016/j.ophtha.2023.12.014

Faricimab Treat-and-Extend for Diabetic Macular Edema: Two-Year Results from the Randomized Phase 3 YOSEMITE and RHINE Trials
YOSEMITE and RHINE Investigators 2024, , Ophthalmology, vol. 131, no. 6, pp. 708-723. https://doi.org/10.1016/j.ophtha.2023.12.026

TENAYA and LUCERNE: Two-Year Results from the Phase 3 Neovascular Age-Related Macular Degeneration Trials of Faricimab with Treat-and-Extend Dosing in Year 2
TENAYA and LUCERNE Investigators 2024, , Ophthalmology. https://doi.org/10.1016/j.ophtha.2024.02.014

Efficacy and safety of avacincaptad pegol in patients with geographic atrophy (GATHER2): 12-month results from a randomised, double-masked, phase 3 trial
GATHER2 trial investigators 2023, , The Lancet, vol. 402, no. 10411, pp. 1449-1458. https://doi.org/10.1016/S0140-6736(23)01583-0

Outcomes in Retinal Detachment Repair and Laser Prophylaxis for Syndromes with Optically Empty Vitreous
Taylor, K, Su, M, Richards, Z, Mamawalla, M, Rao, P & Chang, E 2023, , Ophthalmology Retina, vol. 7, no. 10, pp. 848-856. https://doi.org/10.1016/j.oret.2023.06.012

Efficacy, durability, and safety of faricimab with extended dosing up to every 16 weeks in Japanese patients with diabetic macular edema: 1-year results from the Japan subgroup of the phase 3 YOSEMITE trial
on behalf of the YOSEMITE and RHINE Investigators 2023, , Japanese Journal of Ophthalmology, vol. 67, no. 3, pp. 264-279. https://doi.org/10.1007/s10384-023-00979-8

Typical and atypical clinical presentations of X-Linked retinoschisis: A case series and literature review
Wakabayashi, T, Chang, E, Nudleman, E, El-Rayes, EN & Yonekawa, Y 2023, , Survey of Ophthalmology, vol. 68, no. 3, pp. 347-360. https://doi.org/10.1016/j.survophthal.2023.01.008

The real-world efficacy and safety of faricimab in neovascular age-related macular degeneration: the TRUCKEE study – 6 month results
Khanani, AM, Aziz, AA, Khan, H, Gupta, A, Mojumder, O, Saulebayeva, A, Abbey, AM, Almeida, DRP, Avery, RL, Banda, HK, Barakat, MR, Bhandari, R, Chang, EY, Haug, SJ, London, NJS, Mein, L, Sheth, VS, Wolfe, JD, Singer, MA & Danzig, CJ 2023, , Eye (Basingstoke), vol. 37, no. 17, pp. 3574-3581. https://doi.org/10.1038/s41433-023-02553-5

Shedding light on the rate and timing of cataract extractions for pediatric patients after vitrectomy
Rao, P, Chang, E & Hubbard, GB 2023, , Retina Today, vol. 2023, no. April, pp. 17-18.

The Prevalence of Retinal Disease and Associated CNS Disease in Young Patients with Incontinentia Pigmenti
Danford, ID, Scruggs, BA, Capone, A, Trese, MT, Drenser, KA, Thanos, A, Nudleman, E, Amphornphruet, A, Tipsuriyaporn, B, Hubbard, GB, Ells, A, Harper, CA, Goldstein, J, Calvo, C, Wallace-Carrete, C, Berry, D, Chang, E, Leishman, L, Shapiro, M, Blair, M, Mikhail, M, Shields, CL, Schwendeman, R, Yonekawa, Y, Gupta, MP, Orlin, A, Prakhunhungsit, S, Mukai, S, Berrocal, A, Hartnett, ME & Campbell, JP 2022, , Ophthalmology Retina, vol. 6, no. 12, pp. 1113-1121. https://doi.org/10.1016/j.oret.2022.05.032

Advances in retinopathy of prematurity imaging
Wakabayashi, T, Patel, SN, Campbell, JP, Chang, EY, Nudleman, ED & Yonekawa, Y 2022, , Saudi Journal of Ophthalmology, vol. 36, no. 3, pp. 243-250. https://doi.org/10.4103/sjopt.sjopt_20_22

Efficacy, durability, and safety of intravitreal faricimab up to every 16 weeks for neovascular age-related macular degeneration (TENAYA and LUCERNE): two randomised, double-masked, phase 3, non-inferiority trials
TENAYA and LUCERNE Investigators 2022, , The Lancet, vol. 399, no. 10326, pp. 729-740. https://doi.org/10.1016/S0140-6736(22)00010-1

Efficacy, durability, and safety of intravitreal faricimab with extended dosing up to every 16 weeks in patients with diabetic macular oedema (YOSEMITE and RHINE): two randomised, double-masked, phase 3 trials
YOSEMITE and RHINE Investigators 2022, , The Lancet, vol. 399, no. 10326, pp. 741-755. https://doi.org/10.1016/S0140-6736(22)00018-6

Loss of Neuron Navigator 2 Impairs Brain and Cerebellar Development
Accogli, A, Lu, S, Musante, I, Scudieri, P, Rosenfeld, JA, Severino, M, Baldassari, S, Iacomino, M, Riva, A, Balagura, G, Piccolo, G, Minetti, C, Roberto, D, Xia, F, Razak, R, Lawrence, E, Hussein, M, Chang, EYH, Holick, M, Calì, E, Aliberto, E, De-Sarro, R, Gambardella, A, Network, UD, Group, SYNPSS, Emrick, L, McCaffery, PJA, Clagett-Dame, M, Marcogliese, PC, Bellen, HJ, Lalani, SR, Zara, F, Striano, P & Salpietro, V 2023, , Cerebellum, vol. 22, no. 2, pp. 206-222. https://doi.org/10.1007/s12311-022-01379-3

Referable Macular Hemorrhage-A Clinically Meaningful Screening Target in Newborn Infants. Position Statement of the Association of Pediatric Retina Surgeons
Wood, EH, Capone, A, Drenser, KA, Berrocal, A, Hubbard, GB, Callaway, NF, Kychenthal, A, Ells, A, Harper, CA, Besirli, CG, Baumal, CR, Vavvas, DG, Chang, EY, Nudleman, ED, Tsui, I, Sears, J, Vajzovic, L, Hartnett, ME, Shapiro, MJ, Quiram, PA, Ozdek, S, Kusaka, S, Wu, WC & Trese, MT 2022, , Ophthalmic Surgery Lasers and Imaging Retina, vol. 53, no. 1, pp. 3-6. https://doi.org/10.3928/23258160-20211214-01

Comparison in Retreatments between Bevacizumab and Ranibizumab Intravitreal Injections for Retinopathy of Prematurity: A Multicenter Study
Retinopathy of Prematurity Injection Consortium (ROPIC) 2023, , Ophthalmology, vol. 130, no. 4, pp. 373-378. https://doi.org/10.1016/j.ophtha.2022.11.012

Belin, PJ, Mundae, R, Tzu, JH, Chang, E & Parke, DW 2021, , Retina, vol. 41, no. 9, pp. 1828-1832. https://doi.org/10.1097/IAE.0000000000003136

Adult retinopathy of prematurity: Treatment implications, long term sequelae, and management
Chang, E & Rao, P 2021, , Current Opinion in Ophthalmology, vol. 32, no. 5, pp. 489-493. https://doi.org/10.1097/ICU.0000000000000787

Traumatic Retinal Detachment in Patients with Self-Injurious Behavior: An International Multicenter Study
Rossin, EJ, Tsui, I, Wong, SC, Hou, KK, Prakhunhungsit, S, Blair, MP, Shapiro, MJ, Leishman, L, Nagiel, A, Lifton, JA, Quiram, P, Ringeisen, AL, Henderson, RH, Arruti, N, Buzzacco, DM, Kusaka, S, Ferrone, PJ, Belin, PJ, Chang, E, Hubschman, JP, Murray, TG, Leung, EH, Wu, WC, Olsen, KR, Harper, CA, Rahmani, S, Goldstein, J, Lee, T, Nudleman, E, Cernichiaro-Espinosa, LA, Chhablani, J, Berrocal, AM & Yonekawa, Y 2021, , Ophthalmology Retina, vol. 5, no. 8, pp. 805-814. https://doi.org/10.1016/j.oret.2020.11.012

Very late-onset reactivation of retinopathy of prematurity post anti-VEGF bevacizumab treatment for type 1 ROP: a case report
Taylor, K, Ghergherehchi, L, Rao, P, Harper, CA & Chang, E 2021, , Journal of AAPOS, vol. 25, no. 3, pp. 180-184. https://doi.org/10.1016/j.jaapos.2021.02.004