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Elvin Blanco, PhD

Assistant Research Professor in Nanomedicine, Institute for Academic Medicine
Assistant Research Member, Research Institute
Houston Methodist


Education & Training

PhD, U.T Southwestern Medical Center
MS, Case Western Reserve University
BS, Case Western Reserve University
Publications

Nanotherapeutics for treatment of pulmonary arterial hypertension
Segura-Ibarra, V, Wu, S, Hassan, N, Moran-Guerrero, JA, Ferrari, M, Guha, A, Karmouty-Quintana, H & Blanco, E 2018, Frontiers in Physiology, vol. 9, no. JUL, 890. DOI: 10.3389/fphys.2018.00890

Nanomedicine, an emerging therapeutic strategy for oral cancer therapy
Marcazzan, S, Varoni, EM, Blanco, E, Lodi, G & Ferrari, M 2018, Oral Oncology, vol. 76, pp. 1-7. DOI: 10.1016/j.oraloncology.2017.11.014

Polymer Functionalization of Isolated Mitochondria for Cellular Transplantation and Metabolic Phenotype Alteration
Wu, S, Zhang, A, Li, S, Chatterjee, S, Qi, R, Segura-Ibarra, V, Ferrari, M, Gupte, A, Blanco, E & Hamilton, DJ 2018, Advanced Science, pp. 1700530-n/a. DOI: 10.1002/advs.201700530

A chloroquine-induced macrophage-preconditioning strategy for improved nanodelivery
Wolfram, J, Nizzero, S, Liu, H, Li, F, Zhang, G, Li, Z, Shen, H, Blanco, E & Ferrari, M 2017, Scientific Reports, vol. 7, no. 1, pp. 13738. DOI: 10.1038/s41598-017-14221-2

Contribution of Kupffer cells to liposome accumulation in the liver
Samuelsson, E, Shen, H, Blanco, E, Ferrari, M & Wolfram, J 2017, Colloids and Surfaces B: Biointerfaces, vol. 158, pp. 356-362. DOI: 10.1016/j.colsurfb.2017.07.014

Nanoparticles administered intrapericardially enhance payload myocardial distribution and retention
Segura-Ibarra, V, Cara, FE, Wu, S, Iruegas-Nunez, DA, Wang, S, Ferrari, M, Ziemys, A, Valderrabano, M & Blanco, E 2017, Journal of Controlled Release, vol. 262, pp. 18-27. DOI: 10.1016/j.jconrel.2017.07.012

Methotraxate-Loaded Hybrid Nanoconstructs Target Vascular Lesions and Inhibit Atherosclerosis Progression in ApoE-/- Mice
Stigliano, C, Ramirez, MR, Singh, JV, Aryal, S, Key, J, Blanco, E & Decuzzi, P 2017, Advanced Healthcare Materials. DOI: 10.1002/adhm.201601286

Rapamycin nanoparticles localize in diseased lung vasculature and prevent pulmonary arterial hypertension
Segura-Ibarra, V, Amione-Guerra, J, Cruz-Solbes, AS, Cara, FE, Iruegas-Nunez, DA, Wu, S, Youker, KA, Bhimaraj, A, Torre-Amione, G, Ferrari, M, Karmouty-Quintana, H, Guha, A & Blanco, E 2017, International Journal of Pharmaceutics, vol. 524, no. 1-2, pp. 257-267. DOI: 10.1016/j.ijpharm.2017.03.069

NESTED PARTICLES AND THE USE THEREOF FOR COORDINATED DELVERY OF ACTIVE AGENTS
Blanco, E 2016, , Patent No. US2016317455, IPC No. A61K 31/ 565 A I.

Enzyme-responsive multistage vector for drug delivery to tumor tissue
Mi, Y, Wolfram, J, Mu, C, Liu, X, Blanco, E, Shen, H & Ferrari, M 2016, Pharmacological Research, vol. 113, pp. 92-99. DOI: 10.1016/j.phrs.2016.08.024

Strategies for improving drug delivery: nanocarriers and microenvironmental priming
Khalid, A, Persano, S, Shen, H, Zhao, Y, Blanco, E, Ferrari, M & Wolfram, J 2016, Expert Opinion on Drug Delivery, pp. 1-13. DOI: 10.1080/17425247.2017.1243527

Label-Free Isothermal Amplification Assay for Specific and Highly Sensitive Colorimetric miRNA Detection
Persano, S, Guevara, ML, Wolfram, J, Blanco, E, Shen, H, Ferrari, M & Pompa, PP 2016, ACS Omega, vol. 1, no. 3, pp. 448-455. DOI: 10.1021/acsomega.6b00109

Nucleic Acid Delivery for Endothelial Dysfunction in Cardiovascular Diseases
Deshpande, D, Janero, DR, Segura-Ibarra, V, Blanco, E & Amiji, MM 2016, Methodist DeBakey Cardiovascular Journal, vol. 12, no. 3, pp. 134-140. DOI: 10.14797/mdcj-12-3-134

A pyruvate decarboxylase-mediated therapeutic strategy for mimicking yeast metabolism in cancer cells
Scott, B, Shen, J, Nizzero, S, Boom, K, Persano, S, Mi, Y, Liu, X, Zhao, Y, Blanco, E, Shen, H, Ferrari, M & Wolfram, J 2016, Pharmacological Research, vol. 111, pp. 413-421. DOI: 10.1016/j.phrs.2016.07.005

Nanotechnology toward advancing personalized medicine
Sakamoto, JH, Godin, B, Hu, Y, Blanco, E, van de Ven, AL, Vellaichamy, A, Murphy, MB, La Francesca, S, Schuenemeyer, T, Given, B, Meyn, A & Ferrari, M 2016, . in Handbook of Clinical Nanomedicine: Law, Business, Regulation, Safety, and Risk. vol. 2, Pan Stanford Publishing Pte. Ltd. pp. 1347-1411. DOI: 10.4032/9789814669238

An injectable nanoparticle generator enhances delivery of cancer therapeutics
Xu, R, Zhang, G, Mai, J, Deng, X, Segura-Ibarra, V, Wu, S, Shen, J, Liu, H, Hu, Z, Chen, L, Huang, Y, Koay, E, Huang, Y, Liu, J, Ensor, JE, Blanco, E, Liu, X, Ferrari, M & Shen, H 2016, Nature Biotechnology, vol. 34, no. 4, pp. 414-418. DOI: 10.1038/nbt.3506

A Micro/Nano Composite for Combination Treatment of Melanoma Lung Metastasis
Mi, Y, Mu, C, Wolfram, J, Deng, Z, Hu, T, Liu, X, Blanco, E, Shen, H & Ferrari, M 2016, Advanced Healthcare Materials, vol. 5, no. 8, pp. 936-46. DOI: 10.1002/adhm.201500910

A specifically designed nanoconstruct associates, internalizes, traffics in cardiovascular cells, and accumulates in failing myocardium: A new strategy for heart failure diagnostics and therapeutics
Ruiz-Esparza, GU, Segura-Ibarra, V, Cordero-Reyes, AM, Youker, KA, Serda, RE, Cruz-Solbes, AS, Amione-Guerra, J, Yokoi, K, Kirui, DK, Cara, FE, Paez-Mayorga, J, Flores-Arredondo, JH, Guerrero-Beltrán, CE, Garcia-Rivas, G, Ferrari, M, Blanco, E & Torre-Amione, G 2016, European Journal of Heart Failure, vol. 18, no. 2, pp. 169-178. DOI: 10.1002/ejhf.463

Principles of nanoparticle design for overcoming biological barriers to drug delivery
Blanco, E, Shen, H & Ferrari, M 2015, Nature Biotechnology, vol. 33, no. 9, pp. 941-951. DOI: 10.1038/nbt.3330

Mass partitioning effects in diffusion transport
Kojic, M, Milosevic, M, Wu, S, Blanco, E, Ferrari, M & Ziemys, A 2015, Physical Chemistry Chemical Physics, vol. 17, no. 32, pp. 20630-20635. DOI: 10.1039/c5cp02720a