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Edward J. Septimus, MD

Adjunct Professor of Medicine, Academic Institute
Houston Methodist


Publications

Improving Sepsis Outcomes in the Era of Pay-for-Performance and Electronic Quality Measures: A Joint IDSA/ACEP/PIDS/SHEA/SHM/SIDP Position Paper
Rhee, C, Strich, JR, Chiotos, K, Classen, DC, Cosgrove, SE, Greeno, R, Heil, EL, Kadri, SS, Kalil, AC, Gilbert, DN, Masur, H, Septimus, EJ, Sweeney, DA, Terry, A, Winslow, DL, Yealy, DM & Klompas, M 2024, , Clinical Infectious Diseases, vol. 78, no. 3, pp. 505-513. https://doi.org/10.1093/cid/ciad447

Use of Real-World EMR Data to Rapidly Evaluate Treatment Effects of Existing Drugs for Emerging Infectious Diseases: Remdesivir for COVID-19 Treatment as an Example
Zhang, C, Nigo, M, Patel, S, Yu, D, Septimus, E & Wu, H 2024, , Statistics in Biosciences. https://doi.org/10.1007/s12561-023-09411-8

Stewardship Prompts to Improve Antibiotic Selection for Pneumonia: The INSPIRE Randomized Clinical Trial
Gohil, SK, Septimus, E, Kleinman, K, Varma, N, Avery, TR, Heim, L, Rahm, R, Cooper, WS, Cooper, M, McLean, LE, Nickolay, NG, Weinstein, RA, Burgess, LH, Coady, MH, Rosen, E, Sljivo, S, Sands, KE, Moody, J, Vigeant, J, Rashid, S, Gilbert, RF, Smith, KN, Carver, B, Poland, RE, Hickok, J, Sturdevant, SG, Calderwood, MS, Weiland, A, Kubiak, DW, Reddy, S, Neuhauser, MM, Srinivasan, A, Jernigan, JA, Hayden, MK, Gowda, A, Eibensteiner, K, Wolf, R, Perlin, JB, Platt, R & Huang, SS 2024, , JAMA: The Journal of the American Medical Association. https://doi.org/10.1001/jama.2024.6248

Stewardship Prompts to Improve Antibiotic Selection for Urinary Tract Infection: The INSPIRE Randomized Clinical Trial
Gohil, SK, Septimus, E, Kleinman, K, Varma, N, Avery, TR, Heim, L, Rahm, R, Cooper, WS, Cooper, M, McLean, LE, Nickolay, NG, Weinstein, RA, Burgess, LH, Coady, MH, Rosen, E, Sljivo, S, Sands, KE, Moody, J, Vigeant, J, Rashid, S, Gilbert, RF, Smith, KN, Carver, B, Poland, RE, Hickok, J, Sturdevant, SG, Calderwood, MS, Weiland, A, Kubiak, DW, Reddy, S, Neuhauser, MM, Srinivasan, A, Jernigan, JA, Hayden, MK, Gowda, A, Eibensteiner, K, Wolf, R, Perlin, JB, Platt, R & Huang, SS 2024, , JAMA: The Journal of the American Medical Association. https://doi.org/10.1001/jama.2024.6259

Risk of Misleading Conclusions in Observational Studies of Time-to-Antibiotics and Mortality in Suspected Sepsis
Pak, TR, Young, J, McKenna, CS, Agan, A, Dellostritto, L, Filbin, MR, Dutta, S, Kadri, SS, Septimus, EJ, Rhee, C & Klompas, M 2023, , Clinical Infectious Diseases, vol. 77, no. 11, pp. 1534-1543. https://doi.org/10.1093/cid/ciad450

Ten golden rules for optimal antibiotic use in hospital settings: the WARNING call to action
Worldwide Antimicrobial Resistance National/International Network Group (WARNING) Collaborators 2023, , World Journal of Emergency Surgery, vol. 18, no. 1, 50. https://doi.org/10.1186/s13017-023-00518-3

Executive Summary: A Compendium of Strategies to Prevent Healthcare-Associated Infections in Acute-Care Hospitals: 2022 Updates
Yokoe, DS, Advani, SD, Anderson, DJ, Babcock, HM, Bell, M, Berenholtz, SM, Bryant, KA, Buetti, N, Calderwood, MS, Calfee, DP, Dubberke, ER, Ellingson, KD, Fishman, NO, Gerding, DN, Glowicz, J, Hayden, MK, Kaye, KS, Klompas, M, Kociolek, LK, Landon, E, Larson, EL, Malani, AN, Marschall, J, Meddings, J, Mermel, LA, Patel, PK, Perl, TM, Popovich, KJ, Schaffzin, JK, Septimus, E, Trivedi, KK, Weinstein, RA & Maragakis, LL 2023, , Infection Control and Hospital Epidemiology, vol. 44, no. 10, pp. 1540-1554. https://doi.org/10.1017/ice.2023.138

Introduction to A Compendium of Strategies to Prevent Healthcare-Associated Infections In Acute-Care Hospitals: 2022 Updates
Yokoe, DS, Advani, SD, Anderson, DJ, Babcock, HM, Bell, M, Berenholtz, SM, Bryant, KA, Buetti, N, Calderwood, MS, Calfee, DP, Deloney, VM, Dubberke, ER, Ellingson, KD, Fishman, NO, Gerding, DN, Glowicz, J, Hayden, MK, Kaye, KS, Kociolek, LK, Landon, E, Larson, EL, Malani, AN, Marschall, J, Meddings, J, Mermel, LA, Patel, PK, Perl, TM, Popovich, KJ, Schaffzin, JK, Septimus, E, Trivedi, KK, Weinstein, RA & Maragakis, LL 2023, , Infection Control and Hospital Epidemiology, vol. 44, no. 10, pp. 1533-1539. https://doi.org/10.1017/ice.2023.158

Nasal Iodophor Antiseptic vs Nasal Mupirocin Antibiotic in the Setting of Chlorhexidine Bathing to Prevent Infections in Adult ICUs: A Randomized Clinical Trial
Huang, SS, Septimus, EJ, Kleinman, K, Heim, LT, Moody, JA, Avery, TR, McLean, L, Rashid, S, Haffenreffer, K, Shimelman, L, Staub-Juergens, W, Spencer-Smith, C, Sljivo, S, Rosen, E, Poland, RE, Coady, MH, Lee, CH, Blanchard, EJ, Reddish, K, Hayden, MK, Weinstein, RA, Carver, B, Smith, K, Hickok, J, Lolans, K, Khan, N, Sturdevant, SG, Reddy, SC, Jernigan, JA, Sands, KE, Perlin, JB & Platt, R 2023, , JAMA: The Journal of the American Medical Association, vol. 330, no. 14, pp. 1337-1347. https://doi.org/10.1001/jama.2023.17219

Society for Healthcare Epidemiology of America Compendium updates 2022
Septimus, EJ 2023, , Current opinion in infectious diseases, vol. 36, no. 4, pp. 263-269. https://doi.org/10.1097/QCO.0000000000000926

The impact of surgical volume on hospital ranking using the standardized infection ratio
Ye, S, Li, D, Yu, T, Caroff, DA, Guy, J, Poland, RE, Sands, KE, Septimus, EJ, Huang, SS, Platt, R & Wang, R 2023, , Scientific Reports, vol. 13, no. 1, 7624, pp. 7624. https://doi.org/10.1038/s41598-023-33937-y

The accuracy of infection diagnoses among patients meeting Sepsis-3 criteria in the emergency department
Adelman, MW, Septimus, EJ & Arias, CA 2023, , Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol. 77, no. 2, pp. 327. https://doi.org/10.1093/cid/ciad240

Coronavirus disease 2019 (COVID-19) infection prevention practices that exceed Centers for Disease Control and Prevention (CDC) guidance: Balancing extra caution against impediments to care
Gohil, SK, Septimus, E, Sands, KE, Blanchard, EJ, Moody, J, De St. Maurice, A, Yokoe, D, Kwon, J, Grein, J, Cohen, S, Uslan, D, Vasudev, M, Mauricio, A, Mabalot, S, Coady, MH, Sljivo, S, Smith, K, Carver, B, Poland, R, Perlin, J, Platt, R & Huang, SS 2023, , Infection Control and Hospital Epidemiology, vol. 44, no. 12, pp. 2074-2077. https://doi.org/10.1017/ice.2023.89

Public Health Interventions Guided by Houston’s Wastewater Surveillance Program During the COVID-19 Pandemic
Hopkins, L, Ensor, KB, Stadler, L, Johnson, CD, Schneider, R, Domakonda, K, McCarthy, JJ, Septimus, EJ, Persse, D & Williams, SL 2023, , Public Health Reports, vol. 138, no. 6, pp. 856-861. https://doi.org/10.1177/00333549231185625

The Impact of Coronavirus Disease 2019 (COVID-19) on Healthcare-Associated Infections
Baker, MA, Sands, KE, Huang, SS, Kleinman, K, Septimus, EJ, Varma, N, Blanchard, J, Poland, RE, Coady, MH, Yokoe, DS, Fraker, S, Froman, A, Moody, J, Goldin, L, Isaacs, A, Kleja, K, Korwek, KM, Stelling, J, Clark, A, Platt, R & Perlin, JB 2022, , Clinical Infectious Diseases, vol. 74, no. 10, pp. 1748-1754. https://doi.org/10.1093/cid/ciab688

Heterogeneity in Clinical Presentations of Sepsis: Challenges and Implications for "one-Size-Fits-All" Time-to-Antibiotic Measures*
Rhee, C & Septimus, EJ 2022, , Critical Care Medicine, vol. 50, no. 5, pp. 886-889. https://doi.org/10.1097/CCM.0000000000005430

National Healthcare Safety Network 2018 Baseline Neonatal Standardized Antimicrobial Administration Ratios
OLeary, EN, Edwards, JR, Srinivasan, A, Neuhauser, MM, Soe, MM, Webb, AK, Edwards, EM, Horbar, JD, Soll, RF, Roberts, J, Hicks, LA, Wu, H, Zayack, D, Braun, D, Cali, S, Edwards, WH, Flannery, DD, Fleming-Dutra, KE, Guzman-Cottrill, JA, Kuzniewicz, M, Lee, GM, Newland, J, Olson, J, Puopolo, KM, Rogers, SP, Schulman, J, Septimus, E & Pollock, DA 2022, , Hospital pediatrics, vol. 12, no. 2, pp. 190-197. https://doi.org/10.1542/hpeds.2021-006253

Recommendations for change in infection prevention programs and practice
Garcia, R, Barnes, S, Boukidjian, R, Goss, LK, Spencer, M, Septimus, EJ, Wright, MO, Munro, S, Reese, SM, Fakih, MG, Edmiston, CE & Levesque, M 2022, , American Journal of Infection Control, vol. 50, no. 12, pp. 1281-1295. https://doi.org/10.1016/j.ajic.2022.04.007

Development of the invasive candidiasis discharge [I Can discharge] model: a mixed methods analysis
Jo, J, Tran, TT, Beyda, ND, Simmons, D, Hendrickson, JA, Almutairi, MS, Alnezary, FS, Gonzales-Luna, AJ, Septimus, EJ & Garey, KW 2022, , European Journal of Clinical Microbiology and Infectious Diseases, vol. 41, no. 10, pp. 1207-1213. https://doi.org/10.1007/s10096-022-04473-w

Universal MRSA/Staphylococcal Decolonization for Hospitalized Patients
Septimus, EJ 2022, . in Infection Prevention: New Perspectives and Controversies: Second Edition. Springer International Publishing, pp. 101-110. https://doi.org/10.1007/978-3-030-98427-4_9